• 콘크리트학회논문집
• /
• 제17권5호
• /
• pp.857-868
• /
• 2005

This paper deals with the accumulated damage in concrete structures due to the cyclic freeze-thaw as an environmental load. The cyclic ice body nucleation and growth processes in porous systems are affected by the thermo-physical and mass transport properties, and gradients of temperature and chemical potentials. Furthermore, the diffusivity of deicing chemicals shows significantly higher value under cyclic freeze-thaw conditions. Consequently, the disintegration of concrete structures is aggravated at marine environments, higher altitudes, and northern areas. However, the properties of cyclic freeze-thaw with crack growth and diffusion of chloride ion effects are hard to be identified in tests, and there has been no analytic model for the combined degradations. The main objective is to determine the driving force and evaluate the reduced strength and stiffness by freeze-thaw. For the development of computational model of those coupled deterioration, micro-pore structure characterization, pore pressure based on the thermodynamic equilibrium, time and temperature dependent super-cooling with or without deicing salts, nonlinear-fracture constitutive relation for the evaluation of internal damage, and the effect of entrained air pores (EA) has been modeled numerically. As a result, the amount of ice volume with temperature dependent surface tensions, freezing pressure and resulting deformations, and cycle and temperature dependent pore volume has been calculated and compared with available test results. The developed computational program can be combined with DuCOM, which can calculate the early aged strength, heat of hydration, micro-pore volume, shrinkage, transportation of free water in concrete. Therefore, the developed model can be applied to evaluate those various practical degradation cases as well.

• International Journal of Concrete Structures and Materials
• /
• 제7권1호
• /
• pp.79-93
• /
• 2013

One of the biggest problems affecting bridges is the transverse cracking and deterioration of concrete bridge decks. The causes of early age cracking are primarily attributed to plastic shrinkage, temperature effects, autogenous shrinkage, and drying shrinkage. The cracks can be influenced by material characteristics, casting sequence, formwork, climate conditions, geometry, and time dependent factors. The cracking of bridge decks not only creates unsightly aesthetic condition but also greatly reduces durability. It leads to a loss of functionality, loss of stiffness, and ultimately loss of structural safety. This investigation consists of field, laboratory, and analytical phases. The experimental and field testing investigate the early age transverse cracking of bridge decks and evaluate the use of sealant materials. The research identifies suitable materials, for crack sealing, with an ability to span cracks of various widths and to achieve performance criteria such as penetration depth, bond strength, and elongation. This paper also analytically examines the effect of a wide range of parameters on the development of cracking such as the number of spans, the span length, girder spacing, deck thickness, concrete compressive strength, dead load, hydration, temperature, shrinkage, and creep. The importance of each parameter is identified and then evaluated. Also, the AASHTO Standard Specification limits liveload deflections to L/800 for ordinary bridges and L/1000 for bridges in urban areas that are subject to pedestrian use. The deflection is found to be an important parameter to affect cracking. A set of recommendations to limit the transverse deck cracks in bridge decks is also presented.

• Computers and Concrete
• /
• 제20권5호
• /
• pp.573-582
• /
• 2017

Chloride-induced cover cracking will aggravate the performance deterioration for RC structures under the chlorideladen environment, which may endanger the safety of structures and occupants. Traditional design method cannot ensure that a definite performance is satisfied. To overcome the defects, a study on the performance-based design method was carried out in this paper. Firstly, the limit state functions were established for the corrosion initiation and cover cracking. Thereafter, the uncertainty analysis was performed to study the effects of random factors on the time-dependent performances. Partial factor formulae were deduced through the first-order reliability method for performance verification. Finally, an illustrative example was presented and the sensitivity of cover depth to other parameters was carried out. It is found that the uncertainties of the random variables have great effects on the required cover depth. It is demonstrated that the performance-based design method can ensure that the target performance can be satisfied and support to formulate a rational maintenance and repair strategy for RC structures under the chloride environment.

• 보존과학회지
• /
• 제25권1호
• /
• pp.25-38
• /
• 2009

경주석빙고(보물 제66호)는 조선시대 얼음 저장고로서 주구성암석은 유백색 색조를 띠고 정동이 발달한 중립질의 알칼리화강암이다. 훼손도 평가 결과, 균열(12.5%), 이격(6.7%), 탈락(25.1%), 박락(20.9%), 백화현상(6.5%), 갈색 변색(9.8%), 암흑색 변색(2.0%) 및 생물에 의한 변색(26.5%) 등이 높은 것으로 확인되었다. 전체적인 물리적 훼손율은 43.7%로 홍예틀 1번과 2번에서, 변색에 의한 훼손율은 68.7%로 북벽에서 가장 높아 석빙고의 훼손 상태가 매우 심각한 것으로 평가되었다. 석빙고 내부는 겨울철을 제외하고 연중 90% 이상의 높은 상대습도를 유지하였으며, 내부 미기후는 외부 기후 변화에 의존하나 외부보다 변동이 현저히 적은 일정한 환경을 유지하고 있었다. 상대습도는 봄과 여름에 98~100%에 최빈값을 보였다. 훼손의 근본적인 요인은 강수와 지하수의 유입 및 결로수에 의한 높은 상대습도와 장기적인 수분 유지시간이다. 이 수분은 생물에 의한 변색, 부재의 재질약화, 구조체의 거동, 백화현상 등을 야기하였다. 한편 입구 전면의 사질토양으로 인한 분진과 부유 입자가 내부의 갈색 및 암흑색 변색을 가중시켰다.

• Smart Structures and Systems
• /
• 제21권3호
• /
• pp.305-320
• /
• 2018

The second half of the 20th century was marked with a significant raise in amount of railway bridges in Austria made of reinforced concrete. Today, many of these bridges are slowly approaching the end of their envisaged service life. Current methodology of assessment and evaluation of structural condition is based on visual inspections, which, due to its subjectivity, can lead to delayed interventions, irreparable damages and additional costs. Thus, to support engineers in the process of structural evaluation and prediction of the remaining service life, the Austrian Federal Railways (${\ddot{O}}$ BB) commissioned the formation of a concept for an anticipatory life cycle management of engineering structures. The part concerning concrete bridges consisted of forming a bridge management system (BMS) in a form of a web-based analysis tool, known as the LeCIE_tool. Contrary to most BMSs, where prediction of a condition is based on Markovian models, in the LeCIE_tool, the time-dependent deterioration mechanisms of chloride- and carbonation-induced corrosion are used as the most common deterioration processes in transportation infrastructure. Hence, the main aim of this article is to describe the background of the introduced tool, with a discussion on exposure classes and crucial parameters of chloride ingress and carbonation models. Moreover, the article presents a verification of the generated analysis tool through service life prediction on a dozen of bridges of the Austrian railway network, as well as a case study with a more detailed description and implementation of the concept applied.

• 약학회지
• /
• 제41권2호
• /
• pp.260-267
• /
• 1997

To establish prediabetes in vitro model concerning the etiology of IDDM(Insulin Dependent Diabetes Mellitus) in cellular level we have designed prediabetes in vitro models in pa ncreatic beta cells. HIT-T15, RINm5F and isolated rat islets were chosen as pancreatic beta cells, and streptozotocin (STZ) used as diabetogenic agent. Degree of beta cell destruction to establish prediabetic in vitro model was determined by cell proliferation and insulin release using thymidine uptake and radio immuno assay. When HIT-T15 and RINm5F cells were treated with STZ, the degree of cell deterioration was dependent upon the origin and passage number of beta cells, and in the case of isolated islets STZ showed the more sensitivity than above two beta cell lines. The concentration and exposure time of STZ treatment to establish prediabetes in vitro model in beta cell lines and isolated rat islets were 2 ~ 10mM, 30 min. and 1 ~ 5mM, 30 min., respectively.

• 약학회지
• /
• 제42권4호
• /
• pp.408-413
• /
• 1998

To establish prediabetes in vitro/ model concerning the etiology of Insulin Dependent Diabetes Mellitus (IDDM) in cellular level we have designed experimental prediabefic model in pancreatic beta cells. RINm5F, HIT-T15 and isolated rat islets were chosen as pancreatic beta cells. Since interleukin-$1{\beta}$-induced beta cell cytotoxicity has been implicated in the autoimmune cytotoxicity of IDDM, we used inteleukin-$1{\beta}$ as diabetogenic agent. For establishment of prediabetic in vitro model, the degree of beta cell deterioration was determined by cell proliferation, insulin release and morphological appearance. Cell proliferation, insulin release and morphology were changed dose-dependently in condition that inteleuldn-$1{\beta}$ was exposured to pancreatic beta cells. The concentration and exposure time of interleukin-$1{\beta}$ to set up prediabetic model in beta cell lines and isolated rat islets were 100${\sim}$1000U/ml, 48hr. And 25${\sim}$100U/ml, 48hr, respectively.

• 환경영향평가
• /
• 제20권5호
• /
• pp.705-716
• /
• 2011

For the efficient discovery of knowledge and information from the observed systems, data mining techniques can be an useful tool for the prediction of water quality at intake station in rivers. Deterioration of water quality can be caused at intake station in dry season due to insufficient flow. This demands additional outflow from dam since some extent of deterioration can be attenuated by dam reservoir operation to control outflow considering predicted water quality. A seasonal occurrence of high ammonia nitrogen ($NH_3$-N) concentrations has hampered chemical treatment processes of a water plant in Geum river. Monthly flow allocation from upstream dam is important for downstream $NH_3$-N control. In this study, prediction models of water quality based on multiple regression (MR), artificial neural network and data mining methods were developed to understand water quality variation and to support dam operations through providing predicted $NH_3$-N concentrations at intake station. The models were calibrated with eight years of monthly data and verified with another two years of independent data. In those models, the $NH_3$-N concentration for next time step is dependent on dam outflow, river water quality such as alkalinity, temperature, and $NH_3$-N of previous time step. The model performances are compared and evaluated by error analysis and statistical characteristics like correlation and determination coefficients between the observed and the predicted water quality. It is expected that these data mining techniques can present more efficient data-driven tools in modelling stage and it is found that those models can be applied well to predict water quality in stream river systems.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
• /
• pp.1037-1040
• /
• 2008

해양 환경에 노출된 구조물의 잔존수명을 예측하기 위해서는 부식 개시기까지의 염화물 침투와 콘크리트 피복 균열과 같은 콘크리트 구조물의 열화현상에 대하여 시간과 공간적 요소를 고려한 분석적 접근 방법의 개발이 필요하다. 이를 위하여 본 연구에서는 유한요소해석 기법을 이용하여 염해에 노출되어 있는 콘크리트 구조물의 생애주기를 시뮬레이션하는 것을 목표로 한다. 내구성 예측을 위한 환경적 변수와 재료의 불확실성을 고려하기 위하여 신뢰성에 기반한 잔존수명의 예측을 위한 유한요소해석 모델링에 Monte Carlo Simulation 기법을 도입하였다. 본 논문에서는 콘크리트 구조물의 신뢰성에 기반한 잔존 내구수명에 대한 일반적 개념과 염화물 이온 침투, 부식 생성물의 팽창, 피복 균열 등에 대한 유한요소 모델에 대해 설명하고, 마지막으로 예제를 통하여 염화물 이온의 집중, 부식 생성물의 팽창등이 콘크리트 구조물의 잔존수명에 미치는 영향에 대해 논의하였다.

• Journal of Chest Surgery
• /
• 제33권3호
• /
• pp.213-220
• /
• 2000

Background: Adhesion of leukocytes to myocardium or vascular endothelium has been known as an importation initial step in the ischemia-reperfusion injury which may affect the cardiac function. Therefore, leukocyte-depleted reperfusion may inhibit ischemia-reperfusion induced functional and ultrastructural deterioration. In this study, we quantified the time-dependent expression of the vascular cell adhesion molecule-1(VCMA-1) on piglet myocardium and demonstrated its relation to functional recovery using isolated piglet heart perfusion model. Material and Method: Neonatal(1 to 3 day old) piglet heart was harvested with 4$^{\circ}C$ University of Wisconsin solution (UWS) and presrved in the same solution for 12 hours. Ex vivo model of an isolated working neonatal piglet heart perfusion consisting of membrane oxygenator and roller-pump was used (Fig. 1). Hearts were grouped into leukocyte-non-depleted (group A, n=8) and leukocyte-depleted group(group B, n=8). In group B, hearts were reperfused with leukocyte-depleted blood using a leukocyte filter (Sepacell R, Asahi Medical, Japan). Segments of right atrium were taken before and after 1, 2, 3, and 4 hours of reperfusion for the evaluation of expression of VCAM-1. The intensity of immunohistochyemical satining of the VCAM-1 on the myocardium were graded semiquantitatively (0 to 4). For the evaluation of myocardial stroke work indices were calculated as well at the same time-points. Result: Mean expressins of VCAM-1 on the myocardium at 0, 1, 2, 3, adn 4 hours of reperfusion were 0.63, 1.44, 1.64, 2.65, and 3.34 in group A, while 0.56, 1.40, 1.50, 1.88 and 2.14 in group B (Fig. 3). Mean stroke work indices at 0.5, 1, 2, 3, and 4 hours after reperfusion were 1.35$\times$104, 1.32$\times$104, 1.14$\times$104, 0.81$\times$104, 0.68$\times$104 erg/gm in group A, while 1.40$\times$104, 1.43$\times$104, 1.43$\times$104, 1.28$\times$104, and 1.12$\times$104 erg/em in group B(Fig. 4). Conclusion : In this study, we demonstrated that leukocyte-depletion attenuated the expression of VCAM-1 during reperfusion and the time-dependent functional deterioration of the myocardium was well correlated with the degree of VCAM-1 expression.