• BMB Reports
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• v.43 no.5
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• pp.369-374
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• 2010

The PC12 is the widely used cell line to study neuronal differentiation. We had extensively investigated the details of protein expression in differentiated PC12 cells by proteomic analysis. The cells were incubated at the presence of nerve growth factor. We had analyzed the expression changes in the differentiating PC12 cells by 2-dimensional electrophoresis and the identification of the proteins using MALDI-TOF MS. By comparing expression pattern in the time course, we identified the candidate genes which are associated with neuronal differentiation. Among these genes, we performed real-time PCR analysis to validate $Idh3{\alpha}$ expression by the time course. To identify the function of $Idh3{\alpha}$ in neuronal differentiation stage, the transfection of $Idh3{\alpha}$ to PC12 cells was performed. As a result, we proved that up-regulation of $Idh3{\alpha}$ causes reduction in neural differentiation of PC12 cells. Based on these data, we suggest that $Idh3{\alpha}$ plays a role to the neuronal differentiation.

• Journal of Intelligence and Information Systems
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• v.20 no.2
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• pp.149-162
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• 2014

Course guidance is a mentoring process which is performed before students register for coming classes. The course guidance plays a very important role to students in checking degree audits of students and mentoring classes which will be taken in coming semester. Also, it is intimately involved with a graduation assessment or a completion of ABEEK certification. Currently, course guidance is manually performed by some advisers at most of universities in Korea because they have no electronic systems for the course guidance. By the lack of the systems, the advisers should analyze each degree audit of students and curriculum information of their own departments. This process often causes the human error during the course guidance process due to the complexity of the process. The electronic system thus is essential to avoid the human error for the course guidance. If the relation data model-based system is applied to the mentoring process, then the problems in manual way can be solved. However, the relational data model-based systems have some limitations. Curriculums of a department and certification systems can be changed depending on a new policy of a university or surrounding environments. If the curriculums and the systems are changed, a scheme of the existing system should be changed in accordance with the variations. It is also not sufficient to provide semantic search due to the difficulty of extracting semantic relationships between subjects. In this paper, we model a course mentoring ontology based on the analysis of a curriculum of computer science department, a structure of degree audit, and ABEEK certification. Ontology-based course guidance system is also proposed to overcome the limitation of the existing methods and to provide the effectiveness of course mentoring process for both of advisors and students. In the proposed system, all data of the system consists of ontology instances. To create ontology instances, ontology population module is developed by using JENA framework which is for building semantic web and linked data applications. In the ontology population module, the mapping rules to connect parts of degree audit to certain parts of course mentoring ontology are designed. All ontology instances are generated based on degree audits of students who participate in course mentoring test. The generated instances are saved to JENA TDB as a triple repository after an inference process using JENA inference engine. A user interface for course guidance is implemented by using Java and JENA framework. Once a advisor or a student input student's information such as student name and student number at an information request form in user interface, the proposed system provides mentoring results based on a degree audit of current student and rules to check scores for each part of a curriculum such as special cultural subject, major subject, and MSC subject containing math and basic science. Recall and precision are used to evaluate the performance of the proposed system. The recall is used to check that the proposed system retrieves all relevant subjects. The precision is used to check whether the retrieved subjects are relevant to the mentoring results. An officer of computer science department attends the verification on the results derived from the proposed system. Experimental results using real data of the participating students show that the proposed course guidance system based on course mentoring ontology provides correct course mentoring results to students at all times. Advisors can also reduce their time cost to analyze a degree audit of corresponding student and to calculate each score for the each part. As a result, the proposed system based on ontology techniques solves the difficulty of mentoring methods in manual way and the proposed system derive correct mentoring results as human conduct.

• The Journal of Korean Association of Computer Education
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• v.20 no.1
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• pp.13-26
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• 2017

The programming(algorithm) automated assessment system is to evaluate automatically the accuracy and time/space efficiency of user's solution to the problem which is provided. This system gives the immediate feedback of the solution, real-time ranking. So, in the course of data structure and algorithm, we can apply the knowledge which we have learned to the problem solving. Especially, in the basic course of learning the syntax of the programming language, the novice student can learn in easy and fun by solving the simple problem. The university students can understand in the easy way the meaning of asymptotic analysis of algorithm in data structure & algorithm course.

• Journal of The Geomorphological Association of Korea
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• v.20 no.3
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• pp.65-77
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• 2013

This study investigated and analyzed the topographic landscape resources of Mureung Valley in Donghae-si from the viewpoint of geotourism in order to suggest the tourism contents and tour course. A total of 29 topographic landscapes were observed; these are broadly divided into 4 features including weathering landform, mountainous landform, fluvial landform, and structural landform. Major topographies are fluvial landform (13) and weathering landform (12). At least 19 topographies (14 sites, 19 topographic landscapes) are currently used as tourism resources, with 10 topographies having potential to be developed as new tourism resources. The 10 topographic landscapes are as follows: (1) Jamryong Bawi (Hidden Dragon Rock), (2) Janggipan Bawi (Korean Chessboard Rock), (3) Nurungji Bawi (Parched Rice Rock), (4) Damjang Bawi (Fence Rock), (5) Gyedan Bawi (Stairs Rock), (6) Heundeul Bawi (Rocking Rock), (7) Jeopsi Bawi (Dish Rock), (8) Dol Umul (Stone Well), (9) Jogak Bawi (Carved Rock), and (10) Dubu Bawi (Topu Rock). The topographic tour course can be divided into 3 routes considering accessibility and time. Route 1 is a basic one that anyone can easily use; Route 2 and 3 can be used by visitors who have more time to spare or who are more active.

• Journal of Navigation and Port Research
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• v.31 no.3 s.119
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• pp.165-172
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• 2007

Logistics needs in Asia are surprisingly increasing due to rapid growth of China in Northeast Asia We are endeavoring to make an economic block in opposition to NAFTA and EU by economic revival, political stability, and easing of exclusive parts between countries as increasing of traffic infra such as asian highway, transcontinental railway in the region of Northeast Asia and as considering diversification of transportation mode. Now, Busan is not a final terminal of this business, and it is not a concreted level in considering an undersea tunnel between Korea and Japan as effort to extend to Japan. Therefore, this study performed an effect analysis which be affected to Northeast Asia and Korea in future by analysis and comparison of a cost and time required of marine transportation and railway before and after construction through course analysis and summary of discussed content until now for undersea tunnel between Korea and Japan. This result expects as a accelerative play for study cf undersea tunnel between Korea and Japan in future. In this result, we estimate that it is an effective things in a cost and time required if undersea tunnel between Korea and Japan is constructed, and we simply searched for theirs effects in the aspects of Northeast Asia, national balanced development, regional economic in Busan, and marine logistics.

• Biomolecules & Therapeutics
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• v.8 no.1
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• pp.63-72
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• 2000

We intended to show some basic requirements for spectrum analysis of electroencephalogram (EEG) by visualizing the differences of the results according to different values of some parameters for analysis. Spectrum analysis is the most popular technique applied for the quantitative analysis of the electroen- cephalographic signals. Each step from signal acquisition through spectrum analysis to presentation of parameters was examined with providing some different values of parameters. The steps are:(1) signal acquisition; (2) spectrum analysis; (3) parameter extractions; and (4) presentation of results. In the step of signal acquisition, filtering and amplification of signal should be considered and sampling rate for analog-to-digital conversion is two-time faster than highest frequency component of signal. For the spectrum analysis, the length of signal or epoch size transformed to a function on frequency domain by courier transform is important. Win dowing method applied for the pre-processing before the analysis should be considered for reducing leakage problem. In the step of parameter extraction, data reduction has to be considered so that statistical comparison can be used in appropriate number of parameters. Generally, the log of power of all bands is derived from the spectrum. For good visualization and quantitative evaluation of time course of the parameters are presented in chronospectrogram.

• Korean Journal of Agricultural Science
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• v.38 no.2
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• pp.285-294
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• 2011

Glucosinolate (GSL) contents were investigated (i) at 1~7 days after sowing (DAS) in seed sprouts and (ii) at 3-7 weeks after sowing for the time-course. Moreover, (iii) They were compared with five different cultivars of rocket salad (Eruca sativa). Seventeen GSLs were separated by HPLC analysis, and 10 GSLs among them were identified as glucoraphanin, sinigrin, glucoalyssin, diglucothiobeinin, glucobrassicanapin, glucoerucin, glucobrassicin, dimeric, 4-mercaptobutyl GSL, 4-methoxy glucobrassicin, gluconasturttin by using LC-APCI-MS analysis, but 7 compounds were not identified. (i) The total GSL content in seed sprouts initially increased up to 3 DAS and then decreased according to their seedling growth. In particular, glucoraphanin known as a strong anti-cancer reagent was found the highest level (5.05 ${\mu}mol/g$ dry wt.) at 3 DAS. The most abundant GSL was glucoerucin ranged from 26.0~49.6 ${\mu}mol/g$ dry wt. (ii) In the time-course, the total GSL contents increased dramatically from 3-week (5.91 ${\mu}mol/g$ dry wt.) to 7-week after sowing (32.2 ${\mu}mol/g$ dry wt.). The major GSLs were glucoraphanin, glucoerucin and 4-methoxy glucobrassicin. (iii) By comparing GSL contents with five different cultivars, the total GSL contents increased from 4-week to 6-week after sowing, regardless of cultivar. In 4-week-old, the order with the total GSL content was "Rucola" > "Rocket Herbs" ${\geqq}$ "Odyssey" > "Takii" > "Herb", but in 6-week-old it is changed as "Takii" > "Herb" > "Odyssey" > "Rucola" > "Rocket Herbs" even there was almost no significantly difference between them.

• Korean Institute of Interior Design Journal
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• no.20
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• pp.17-25
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• 1999

The curriculum analysis of lighting design course in the Interior architecture departments in American universities reveals they share a major concern in the basic lighting theories, the sorts of light source and lighting equipment, daylighting, and interior lighting plav. The curriculum is usually composed of two semesters, the first semester being about lighting theory and simple project, while the second one abut more professional fields of design studio. The curriculum of lighting design at the Interior architecture departments in Korean colleges and universities usually consists of introductory courses in the field. Almost every institution allocated only one semester for the courses, and as the courses should cover the broad range within a short time, they were lacked in the required depth and systematic approach. The analysis also reveals the curriculum in Korea puts emphasis on the interior lighting equipment design, while disregarding the importance of daylighting. In comparison, American institutions have their curriculum focused upon the use of daylighting. The curriculum of lighting design courses in Korea, a major part of space rendering methods in the field of Interior Architecture, should be improved without delay. The courses should be included in the required subjects and the educational aims should be changed from offering a general understanding of the concepts to providing professional knowledge and skills, which would contribute to the competitiveness of the departments.

• The Research Journal of the Costume Culture
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• v.13 no.6 s.59
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• pp.896-909
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• 2005

In need of studies on the kinds and structure of thread, the biggest variable factor in knitwear patterns, this study attempts: to examine the physical properties by thread type to basically establish systematic data in order to utilize various mixture and structure of yarn and to contribute to the development of optical patterns by building a systemic and scientific methods to produce knit wear patterns though a statistical analysis of the relation between the variations and physical properties. The results is as follows: with time, a feature of knit, which causes instability making it difficult to maintain the original shape, related to material properties, the weight and expansibility recovery rate have the greatest influence on the variation of wale lengths, though the amount varies by material. The variation of course contraction is closely related to density, the dense fabrics showing the highest values, due to the bust of the human body, the wale length variation of the front is greater than that of the back, by a regression analysis of material properties and the variations is obtained showing the weight, density and expansibility recovery rate have the greatest influence on the wale extension and course contraction of knit.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.2
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• pp.189-197
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• 2011

As a multidisciplinary study encompassing oceanography and history, we have attempted to reanalyze the course of a historical navel battle, Myungryang Naval Battle(September 16th, 1597 according to the lunar calendar) through hindcasting the paleo-tidal currents and -tides(PTC). Firstly, we conducted harmonic analysis using 6-month current data observed at Uldolmok and 1-year elevation data provided by Korea Ocean Research and Development Institute in order to understand their characteristics and to hindcast the PTC. Observation results show that Uldolmok, ~300m wide, relatively narrow channel, is characterized by a flood-dominant mixed mainly semidiurnal tidal regime induced by relatively-strong shallow water constituents, showing closely a standing wave type of tidal current. Further, we hindcasted PTC on the day of Myungryang Naval Battle. Our results were compared and discussed with results(time and speeds of maximum(flood and ebb) currents and high and low water times) of the previous studies estimated from different methods. Lastly, we reconstruct the course of the event of Myungryang Naval Battle recorded in the Admiral Sun-Sin Yi's War Diary(Nangjung Iigi in Korean) based on our hindcasting results.