• 제목/요약/키워드: Time adjustment

검색결과 1,061건 처리시간 0.023초

아버지의 영아 돌봄에 관한 문헌연구 (A Study of father's care giving in infancy)

  • 김영희
    • 부모자녀건강학회지
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    • 제1권
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    • pp.75-87
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    • 1998
  • These days social and economical changes have influence on the structure of family and the role of family members. Working mothers and widowers with children are increasing because of economical difficulties. Support from relatives are decreasing because of the conspicuous trend toward nuclear families. According to these reasons androgynous fathers are required. Today's fathers in Korea socially and culturally have learned about traditional parenting, but they are changing their fathering styles to meet the demands of the times. However they don't have their own fathering models. Therefore nurses who hold an advantageous position to teach and support from clinic have to encourage them to care their infants. The purposes of this study were to define father's care giving in infancy, understand influencing factors on fathering, and the differences between fathering and mothering, then contribute to nursing implementation for supporting fathers. This study was designed to review references about father's care giving. The results were follows: Six aspects of parent participation were direct care. indirect care, play, decision-making concerning the child, amount of time of sole responsibility for the child and overall availability to the child. Direct care involved feeding, bathing, going to child if child awakens. dressing, putting child to bed, taking child to doctor, nurse, or dentist, transporting child to and from sitter, day care, or school, washing child's hair. Indirect care involved cleaning up after child, preparing child's food, fixing child's broken playthings, washing child's clothes, arranging baby-sitting, shopping for child's toys and clothes, transporting baby-sitter to and from your home. Young fathers were gradually participating in direct care like feeding, taking child to doctor. Father's care giving stimulated mothering and promoted parent-infant relationship. Influencing factors of fathering would be divided into father characteristics, surrounding factors, infant attributes. Father characteristics were age, role perception, relationship with parent. Surrounding factors were the opportunity of early contact, support system, spouse's expectation, marital adjustment, feeding type, past experience of care giving. Infant attributes were temperament, behavior, age, sex. The differences between fathering and mothering were reviewed. Fathers were poor at care giving. but their caring was similar to mother's. This subtle difference positively worked upon infant's growth and development. On the basis of these theoretical data, nurses can empower fathers to cooperate with mothers in caring infants.

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Polymorphism in CYP2C9 as a Non-Critical Factor of Warfarin Dosage Adjustment in Korean Patients

  • Lee, Suk-Hyang;Kim, Jae-Moon;Chung, Chin-Sang;Cho, Kyoung-Joo;Kim, Jeong-Hee
    • Archives of Pharmacal Research
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    • 제26권11호
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    • pp.967-973
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    • 2003
  • Cytochrome P4502C9(CYP2C9) is largely responsible for terminating anticoagulant effect by hydroxylation of S-warfarin to inactive metabolites. Mutations in the CYP2C9 gene result in the expression of allelic variants, CYP2C9*2 and CYP2C9*3 with reduced enzyme activity compared to wild type CYP2C9 *1. The aim of this study was to assess relationship between requirement of warfarin dose and polymorphism in CYP2C9 in Korean population. Patients on warfarin therapy for longer than 1 year were included from July 1999 to December 2000 and categorized as one of four groups; regular dose non-bleeding, regular dose bleeding, low dose non-bleeding and low dose bleeding. Low dose was defined as less than 10 mg/week for 3 consecutive monthly follow-ups. Bleeding complications included minor and major bleedings. Blood samples were processed for DNA extraction, genotyping and sequencing to detect polymorphism in CYP2C9. Demographic data, warfarin dose per week, prothrombin time (INR), indications and co-morbid diseases were assessed for each group. Total 90 patients on warfarin were evaluated; The low dose group has taken warfarin 7.6$\pm$1.7 mg/week, which was significantly lower than 31.4$\pm$0.9 mg/week in the regular dose group (p<0.0001). The measured INR in the low dose group was similar to that of the regular dose group (2.3$\pm$0.7 vs. 2.3$\pm$0.6, p=0.9). Even though there was a higher possibility of CYP2C9 variation in the low dose group, no polymorphism in CYP2C9 was detected. All patients were homozygous C416 in exon 3 for CYP2C9*2 and A1061 in exon 7 for CYP2C9*3. The DNA sequencing data confirmed the homozygous C416 and A 1061 alleles. In conclusion, polymorphism in CYP2C9 is not a critical factor for assessing warfarin dose requirement and risk of bleeding complications in a Korean population.

IEEE 802.15.6 WBAN 환경에서 QoS를 고려한 실시간 트래픽 성능향상에 관한 연구 (A Study on Real Time Traffic Performance Improvement Considering QoS in IEEE 802.15.6 WBAN Environments)

  • 노승민;김정호;강철호
    • 대한전자공학회논문지TC
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    • 제48권4호
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    • pp.84-91
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    • 2011
  • 최근 IEEE 802.15.6 을 중심으로 표준화가 진행중인 WBAN (Wireless Body Area Network) 은 인체 내부 혹은 인체로부터 3 미터 이내의 주변에서 일어나는 근거리 무선통신을 목적으로 하는 네트워크이다. 근거리 무선네트워크에서 효과적인 QoS 조절기법과 오디오 및 비디오 데이터를 한정된 대역폭에서의 효율적인 관리는 사용자 뿐 아니라, 통신네트워크의 부하측면에서도 중요한 요소이다. 본 논문에서는 IEEE 802.15.6 고속 WBAN 표준에서, 한정된 데이터에 대해 수퍼프레임의 조정을 통해 효율적인 대역관리를 해주는 동적 할당 알고리즘과 가중치 공평 큐잉(WFQ:Weighted Fair Queueing) 알고리즘을 제안한다. 이것은 Quality of Service (QoS)를 기준으로 한 큐잉 알고리즘을 바탕으로 QoS의 질적인 요소에 대해 robust한 성능을 나타내며 공평성을 유지하고 시스템 성능을 최대화하는 효율적인 알고리즘이다. 제안한 알고리즘에 대한 성능평가 결과, 동적 할당을 적용한 경우 전송대역폭은 최대 5배가 확장되었으며, 가중치 공평큐잉을 적용한 경우 throughput은 최대 24.3%가 개선되고, delay bound 문제가 해결됨을 확인할 수 있었다.

떫은감 경영 표준진단표의 개발 및 현지 적용 (The Development and Application of Standard Diagnostic Table for Astringent Persimmon Management)

  • 전준헌;이성연;이정민;지동현;오찬진
    • 한국산림과학회지
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    • 제104권3호
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    • pp.488-494
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    • 2015
  • 경영 표준진단표를 통해 재배자 스스로 경영 진단을 할 수 있도록 하고 이를 참고하여 임가 경영 개선에 도움이 되고자 떫은감 경영 표준진단표를 개발하여 주산단지의 임가를 대상으로 적용하였다. 떫은감 경영 표준진단표는 임가 일반 현황과 경영 성과 지표, 그리고 경영 진단을 위한 3개의 대분류 항목과 18개의 중분류 항목으로 구성되어 있다. 떫은감 경영 표준진단표 작성을 위해 떫은감 주산단지 10개 시 군 241임가의 경영 실태 조사를 실시하였으며 경영수준 진단을 위해서 18개 중분류 항목의 점수를 합산하여 총점을 산출하였다. 조사 결과 241임가의 평균 점수는 57.4점이었으며 전체 임가의 62%가 40점 이상 60점 미만에 해당하는 것으로 나타났다. 세부 진단항목 결과를 살펴보면 경영기반 지표에서는 나무높이 항목의 점수가 충남 지역에서만 평균 점수보다 현저히 낮은 점수를 나타냈는데 이는 조사 지역의 나무가 30년 이상 된 고령목들이 많아 영향을 준 것으로 생각된다. 생산기술 지표에서 결실조절 항목의 전국 평균 점수는 1.96점으로 상당히 낮은데 떫은감은 단감과 달리 적뢰 적과를 거의 하지 않고 자연 낙과를 통해 스스로 조절하는 경우가 많기 때문이다. 경영 및 판매능력 지표의 자재구입 항목에서는 전국 평균 점수가 2.01점으로 조사 임가의 60% 이상이 대부분의 자재를 개별적으로 선택하고 협상하여 구입한다고 응답하였다. 공동으로 구입한다고 응답한 임가들은 대부분 작목반 단체로 구입하는 경우인 것으로 나타났다.

Parathyroid Hormone Gene rs6256 and Calcium Sensing Receptor Gene rs1801725 Variants are not Associated with Susceptibility to Colorectal Cancer in Iran

  • Mahmoudi, Touraj;Karimi, Khatoon;Arkani, Maral;Farahani, Hamid;Nobakht, Hossein;Dabiri, Reza;Asadi, Asadollah;Zali, Mohammad Reza
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권15호
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    • pp.6035-6039
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    • 2014
  • Background: Substantial evidence from epidemiological studies has suggested that increased levels of calcium may play a protective role against colorectal cancer (CRC). Given the vital role of calcium sensing receptor (CaSR) and parathyroid hormone (PTH) in the maintenance of calcium homeostasis, we explored whether the rs1801725 (A986S) variant located in exon 7 of the CaSR gene and the rs6256 variant located in exon 3 of PTH gene might be associated with CRC risk. Materials and Methods: In this study 860 subjects including 350 cases with CRC and 510 controls were enrolled and genotyped using PCR-RFLP methods. Results: We observed no significant difference in genotype or allele frequencies between the cases with CRC and controls for both CaSR and PTH genes either before or after adjustment for confounding factors including age, BMI, sex, smoking status, and family history of CRC. Furthermore, no evidence for effect modification of any association of rs1801725 and rs6256 variants and CRC by BMI, sex, or tumor site was observed. In addition, there was no significant difference in genotype and allele frequencies between the normal weight (BMI < $25kg/m^2$) cases and overweight/obese (BMI ${\geq}25kg/m^2$) cases for the two SNPs. Conclusions: These data indicated that the CaSR gene A986S variant is not a genetic contributor to CRC risk in the Iranian population. Furthermore, our results suggest for the first time that PTH gene variant does not affect CRC risk. Nonetheless, further studies with larger sample size are needed to validate these findings.

CCDC26 Gene Polymorphism and Glioblastoma Risk in the Han Chinese Population

  • Wei, Xiao-Bing;Jin, Tian-Bo;Li, Gang;Geng, Ting-Ting;Zhang, Jia-Yi;Chen, Cui-Ping;Gao, Guo-Dong;Chen, Chao;Gong, Yong-Kuan
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권8호
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    • pp.3629-3633
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    • 2014
  • Background: Glioblastoma (GBM) is an immunosuppressive tumor whose median survival time is only 12-15 months, and patients with GBM have a uniformly poor prognosis. It is known that heredity contributes to formation of glioma, but there are few genetic studies concerning GBM. Materials and Methods: We genotyped six tagging SNPs (tSNP) in Han Chinese GBM and control patients. We used Microsoft Excel and SPSS 16.0 statistical package for statistical analysis and SNP Stats to test for associations between certain tSNPs and risk of GBM in five different models. ORs and 95%CIs were calculated for unconditional logistic-regression analysis with adjustment for age and gender. The SHEsis software platform was applied for analysis of linkage disequilibrium, haplotype construction, and genetic associations at polymorphism loci. Results: We found rs891835 in CCDC26 to be associated with GBM susceptibility at a level of p=0.009. The following genotypes of rs891835 were found to be associated with GBM risk in four different models of gene action: i) genotype GT (OR=2.26; 95%CI, 1.29-3.97; p=0.019) or GG (OR=1.33; 95%CI, 0.23-7.81; p=0.019) in the codominant model; ii) genotypes GT and GG (OR=2.18; 95%CI, 1.26-3.78; p=0.0061) in the dominant model; iii) GT (OR=2.24; 95%CI, 1.28-3.92; p=0.0053) in the overdominant model; iv) the allele G of rs891835 (OR=1.85; 95%CI, 1.14-3.00; p=0.015) in the additive model. In addition, "CG" and "CGGAG" were found by haplotype analysis to be associated with increased GBM risk. In contrast, genotype GG of CCDC26 rs6470745 was associated with decreased GBM risk (OR=0.34; 95%CI, 0.12-1.01; p=0.029) in the recessive model. Conclusions: Our results, combined with those from previous studies, suggest a potential genetic contribution of CCDC26 to GBM progression among Han Chinese.

진주시 소방서비스 취약지역 개선을 위한 소방권역 조정 (Fire District Adjustment for Improving Fire Service Vulnerable Areas in Jinju)

  • 유환희;구슬
    • 대한공간정보학회지
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    • 제21권1호
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    • pp.19-26
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    • 2013
  • 본 연구에서는 진주시에 현재 설치된 119안전센터에 대해 소방서비스 취약지역을 분석하고 취약지역의 서비스 개선을 위한 방법으로 기존의 센터의 이전이나 새로운 증설방안을 OD cost matrix분석을 통해 소방권역을 분석하였다. 그 결과 진주시의 행정구역 면적에 비하여 119안전센터의 수가 절대적으로 부족한 것을 알 수 있었다. 특히 진주시에 있는 5개 119안전센터 중 국가산업단지가 조성되고 있는 천전119안전센터와 신도시개발에 따른 인구증가로 화재 위험도가 날로 증대되는 문산119안전센터(반성119지역대 포함)의 소방서비스 관할구역을 재조정하거나 센터의 이전 및 증설이 요구되었다. 또한 OD cost matrix분석을 통해 현재의 천전119안전센터를 가호동으로 이전할 경우 중요 취약지역인 정촌산업단지의 소방서비스 시간을 8분에서 3.3분으로 단축할 수 있었으며, 최근 신도시 개발로 인구가 급격히 증가한 금산면지역에 안전센터 증설이 필요함을 알 수 있었다.

Validation of Prediction Equations to Estimate the Energy Values of Feedstuffs for Broilers: Performance and Carcass Yield

  • Alvarenga, R.R.;Rodrigues, P.B.;Zangeronimo, M.G.;Makiyama, L.;Oliveira, E.C.;Freitas, R.T.F.;Lima, R.R.;Bernardino, V.M.P.
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권10호
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    • pp.1474-1483
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    • 2013
  • The objective was to evaluate the use of prediction equations based on the chemical composition of feedstuffs to estimate the values of apparent metabolisable energy corrected for nitrogen balance (AMEn) of corn and soybean meal for broilers. For performance and carcass characteristics, 1,200 one-d-old birds (male and female) were allotted to a completely randomised factorial $2{\times}8$ (two genders and eight experimental diets) with three replicates of each sex with 25 birds. In the metabolism trial, 240 eight-d-old birds were distributed in the same design, but with a split plot in time (age of evaluation) with five, four and three birds per plot, respectively, in stages 8 to 21, 22 to 35, and 36 to 42 d of age. The treatments consisted of the use of six equations systems to predict the AMEn content of feedstuffs, tables of food composition and AMEn values obtained by in vivo assay, totalling eight treatments. Means were compared by Scott-Knott test at 5% probability and a confidence interval of 95% was used to check the fit of the energy values of the diets to the requirements of the birds. As a result of this study, the use of prediction equations resulted in better adjustment to the broiler requirements, resulting in better performance and carcass characteristics compared to the use of tables, however, the use of energy values of feedstuffs obtained by in vivo assay is still the most effective. The best equations were: AMEn = 4,021.8-227.55 Ash (for corn) combined with AMEn = -822.33+69.54 CP-45.26 ADF+90.81 EE (for soybean meal); AMEn = 36.21 CP+85.44 EE+37.26 NFE (nitrogen-free extract) (for corn) combined with AMEn = 37.5 CP+46.39 EE+14.9 NFE (for soybean); and AMEn = 4,164.187+51.006 EE-197.663 Ash-35.689 CF-20.593 NDF (for corn and soybean meal).

수종 복합레진에 있어서 효소 역할에 의한 표면 경도와 조도 변화에 관한 연구 (THE STUDY OF CHANGE IN SURFACE HARDNESS AND TEXTURES OF COMPOSITE RESIN DUE TO ENZYMATIC ACTION)

  • 김미리;이명종
    • Restorative Dentistry and Endodontics
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    • 제20권1호
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    • pp.193-213
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    • 1995
  • The purpose of this study is to investigate a possible contribution of nonspecific esterases, which occur in the oral cavity, to the degradation of ester bonds in polymethacrylates. One of the problems connected with the use of composite resins for restorations is their inadequate resistance to wear. It has been shown that methacrylate hydrolysis can be catalyzed by enzymes and that a carboxylic hydrolase (porcine liver esterase) catalyzed the hydrolysis of several mono - and dimethacrylates. The softening effect on a BISGMA/TEGDMA polymer induced by hydrolase will accelerate the in vivo wear of the polymer. Porcine liver esterase (EC 3.1.1.1) 3.2 mol/L $(NH_4)_2$ $SO_4$ was obtained from Sigma Chemical Company. The esterase activity of one unit is defined as the amount of enzyme capable of hydrolyzing $l{\mu}mol$ ethyl butyrate per min at pH 8.0 AT $25^{\circ}C$. Phosphate buffer, 10mmol/L, pH 7.0, was made by adjustment of a solution of $Na_2HPO_4$ with $H_3PO_4$. Composite resins used in this study are Silux Plus, Z-100, Durafil VS, and Prisma APH. Cylindrical specimens, 14mm in diameter and 3mm thick, of Silux Plus, Z-100, Durafil VS, Prisma APH were polymerized under the celluloid strip. 60 specimens were divided into 2 groups. One group was emersed only in buffer solution, the other group was emersed in buffer and enzyme solution. Silux Plus and Z-100 were divided into 2 subgroups, one subgroup was cured only Visilux 2. And the other subgroup was cured Visilux 2 and Triaid II. Thereafter, specimens were polished to its best achievable surface according to manufacture's directions. The Vickers hardness of the specimens was measured after 1, 2, 4, 7, 9, 15, 50 days. The solutions were changed after each measurement. Composite resin surfaces were evaluated for the surface roughness with profilometer (${\alpha}$-step 200, Tencor instruments, USA) after 1 and 50 days. And then surfaces of specimens were pictured with stereosopy after 1 and 50 days. The results were as follows. 1. The surface hardness of Silux plus, durafil VS, and Prisma APH were decreased with time. But, the surface hardness of Z-100 was not decreased. 2. The surface hardness of all composite resins was decreased by esterase. 3. Composite resins, which were light-cured by Visilux 2 and concomitantly baked by oven, showed more hardened surface than light-cured by Visilux 2 only. 4. Significant surface changes were occured in Silux plus after esterase treatment.

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지역별 단독주택 에너지 절감 리모델링 전략 민감도 분석 (Sensitivity Analysis of Energy Efficient Refurbishment Strategies for Detached Houses in Three Climate Zones)

  • 이병연
    • 한국산학기술학회논문지
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    • 제21권9호
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    • pp.518-527
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    • 2020
  • 그린 리모델링 전략 수립이 기술 중심적으로 진행되어 현장 상황을 반영한 맞춤형 전략 수립의 필요성이 제기된다. 본 논문은 리모델링 활성화를 위하여 현장에 적합한 리모델링 전략수립 방법론으로 민감도 분석을 통한 기술전략 평가와 활용가능성 분석을 목적으로 한다. 30평형 규모 단독주택을 대상으로 에너지플러스엔진과 모드프론티어 최적화 기법을 통합하여 활용하여 서울, 대전, 부산지역에 1980년대 이전, 1984년, 2010년 준공기준을 적용한 총 9개 모델 대상 최적화 후 민감도 분석을 통한 리모델링 전략 우선순위를 도출하였다. 1980년 이전 모델의 경우 지붕 단열성능 강화 전략이 민감도 상위 순위를 갖는 것으로 나타났다. 창호 총일사취득율 기준은 전 지역, 전 준공 시기를 막론하고 다음 상위 민감도를 갖으며, 이는 열관류율 중심 기준에서 총일사취득율 기준을 포함하는 성능 기준으로 확대될 필요가 있음을 보여준다. 대규모 철거공사를 수반하는 창면적비의 조정은 민감도가 낮아 형상 유지 리모델링의 효용을 확인하였다. 사례별 상이한 민감도 결과는 리모델링 전략 수립에서 민감도 분석을 경제성, 시공성 등의 기준 등과 함께 종합적인 리모델링 전략 수립의 가능성을 제시한다.