• Korean Parent-Child Health Journal
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• v.1
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• pp.75-87
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• 1998

These days social and economical changes have influence on the structure of family and the role of family members. Working mothers and widowers with children are increasing because of economical difficulties. Support from relatives are decreasing because of the conspicuous trend toward nuclear families. According to these reasons androgynous fathers are required. Today's fathers in Korea socially and culturally have learned about traditional parenting, but they are changing their fathering styles to meet the demands of the times. However they don't have their own fathering models. Therefore nurses who hold an advantageous position to teach and support from clinic have to encourage them to care their infants. The purposes of this study were to define father's care giving in infancy, understand influencing factors on fathering, and the differences between fathering and mothering, then contribute to nursing implementation for supporting fathers. This study was designed to review references about father's care giving. The results were follows: Six aspects of parent participation were direct care. indirect care, play, decision-making concerning the child, amount of time of sole responsibility for the child and overall availability to the child. Direct care involved feeding, bathing, going to child if child awakens. dressing, putting child to bed, taking child to doctor, nurse, or dentist, transporting child to and from sitter, day care, or school, washing child's hair. Indirect care involved cleaning up after child, preparing child's food, fixing child's broken playthings, washing child's clothes, arranging baby-sitting, shopping for child's toys and clothes, transporting baby-sitter to and from your home. Young fathers were gradually participating in direct care like feeding, taking child to doctor. Father's care giving stimulated mothering and promoted parent-infant relationship. Influencing factors of fathering would be divided into father characteristics, surrounding factors, infant attributes. Father characteristics were age, role perception, relationship with parent. Surrounding factors were the opportunity of early contact, support system, spouse's expectation, marital adjustment, feeding type, past experience of care giving. Infant attributes were temperament, behavior, age, sex. The differences between fathering and mothering were reviewed. Fathers were poor at care giving. but their caring was similar to mother's. This subtle difference positively worked upon infant's growth and development. On the basis of these theoretical data, nurses can empower fathers to cooperate with mothers in caring infants.

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.967-973
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• 2003

Cytochrome P4502C9(CYP2C9) is largely responsible for terminating anticoagulant effect by hydroxylation of S-warfarin to inactive metabolites. Mutations in the CYP2C9 gene result in the expression of allelic variants, CYP2C9*2 and CYP2C9*3 with reduced enzyme activity compared to wild type CYP2C9 *1. The aim of this study was to assess relationship between requirement of warfarin dose and polymorphism in CYP2C9 in Korean population. Patients on warfarin therapy for longer than 1 year were included from July 1999 to December 2000 and categorized as one of four groups; regular dose non-bleeding, regular dose bleeding, low dose non-bleeding and low dose bleeding. Low dose was defined as less than 10 mg/week for 3 consecutive monthly follow-ups. Bleeding complications included minor and major bleedings. Blood samples were processed for DNA extraction, genotyping and sequencing to detect polymorphism in CYP2C9. Demographic data, warfarin dose per week, prothrombin time (INR), indications and co-morbid diseases were assessed for each group. Total 90 patients on warfarin were evaluated; The low dose group has taken warfarin 7.6$\pm$1.7 mg/week, which was significantly lower than 31.4$\pm$0.9 mg/week in the regular dose group (p<0.0001). The measured INR in the low dose group was similar to that of the regular dose group (2.3$\pm$0.7 vs. 2.3$\pm$0.6, p=0.9). Even though there was a higher possibility of CYP2C9 variation in the low dose group, no polymorphism in CYP2C9 was detected. All patients were homozygous C416 in exon 3 for CYP2C9*2 and A1061 in exon 7 for CYP2C9*3. The DNA sequencing data confirmed the homozygous C416 and A 1061 alleles. In conclusion, polymorphism in CYP2C9 is not a critical factor for assessing warfarin dose requirement and risk of bleeding complications in a Korean population.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.4
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• pp.84-91
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• 2011

Recently, WBAN(Wireless Body Area Network) which has progressed standardization based on IEEE 802.15.6 standardization is a network for the purpose of the short-range wireless communications within around 3 meters from the inner or outer human body. Effective QoS control technique and data efficient management in limited bandwidth such as audio and video are important elements in terms of users and loads in short-range wireless networks. In this paper, for high-speed WBAN IEEE 802.15.6 standard, the dynamic allocation to give an efficient bandwidth management and weighted fair queueing algorithm have been proposed through the adjustment of the super-frame about limited data and Quality of Service (QoS) based on the queuing algorithm. Weighted Fair Queueing(WFQ) Algorithm represents the robust performance about elements to qualitative aspects as well as maintaining fairness and maximization of system performance. The performance results show that the dynamic allocation expanded transmission bandwidth five times and the weighted fair queueing increased maximum 24.3 % throughput and also resolved delay bound problem.

• Journal of Korean Society of Forest Science
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• v.104 no.3
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• pp.488-494
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• 2015

This study aims to develop and apply a standard management self-diagnostic table for forestry households to better manage their astringent persimmon production. The diagnostic table consisted of 3 categories (general status of a forestry household, management performance indicators, level of management) and 18 subcategories. The current management status across 241 households was surveyed among 10 chief astringent persimmon producing municipalities. Scores from the 18 subcategories were aggregated for a total score to evaluate and compare different levels of management. The respondents scored an overall average of 57.4, 62% of which were placed between 40 and 60. Upon close examination Chungcheongnam-do scored a very low score in the 'management system-tree height' subcategory with respect to the average score potentially because of the large population of aged trees in the region. The national average in the 'production skills-time of fruit load adjustment' subcategory was only 1.96 because unlike sweet persimmons astringent persimmons adjust their own load by inducing physiological fruit drop. The national average in the 'management/sales skills-material purchase' subcategory was 2.01; over 60% of the respondents indicated a preference for independent selection and purchase for most materials. The households preferring a group purchase tended to utilize the regional co-op.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6035-6039
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• 2014

Background: Substantial evidence from epidemiological studies has suggested that increased levels of calcium may play a protective role against colorectal cancer (CRC). Given the vital role of calcium sensing receptor (CaSR) and parathyroid hormone (PTH) in the maintenance of calcium homeostasis, we explored whether the rs1801725 (A986S) variant located in exon 7 of the CaSR gene and the rs6256 variant located in exon 3 of PTH gene might be associated with CRC risk. Materials and Methods: In this study 860 subjects including 350 cases with CRC and 510 controls were enrolled and genotyped using PCR-RFLP methods. Results: We observed no significant difference in genotype or allele frequencies between the cases with CRC and controls for both CaSR and PTH genes either before or after adjustment for confounding factors including age, BMI, sex, smoking status, and family history of CRC. Furthermore, no evidence for effect modification of any association of rs1801725 and rs6256 variants and CRC by BMI, sex, or tumor site was observed. In addition, there was no significant difference in genotype and allele frequencies between the normal weight (BMI < $25kg/m^2$) cases and overweight/obese (BMI ${\geq}25kg/m^2$) cases for the two SNPs. Conclusions: These data indicated that the CaSR gene A986S variant is not a genetic contributor to CRC risk in the Iranian population. Furthermore, our results suggest for the first time that PTH gene variant does not affect CRC risk. Nonetheless, further studies with larger sample size are needed to validate these findings.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3629-3633
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• 2014

Background: Glioblastoma (GBM) is an immunosuppressive tumor whose median survival time is only 12-15 months, and patients with GBM have a uniformly poor prognosis. It is known that heredity contributes to formation of glioma, but there are few genetic studies concerning GBM. Materials and Methods: We genotyped six tagging SNPs (tSNP) in Han Chinese GBM and control patients. We used Microsoft Excel and SPSS 16.0 statistical package for statistical analysis and SNP Stats to test for associations between certain tSNPs and risk of GBM in five different models. ORs and 95%CIs were calculated for unconditional logistic-regression analysis with adjustment for age and gender. The SHEsis software platform was applied for analysis of linkage disequilibrium, haplotype construction, and genetic associations at polymorphism loci. Results: We found rs891835 in CCDC26 to be associated with GBM susceptibility at a level of p=0.009. The following genotypes of rs891835 were found to be associated with GBM risk in four different models of gene action: i) genotype GT (OR=2.26; 95%CI, 1.29-3.97; p=0.019) or GG (OR=1.33; 95%CI, 0.23-7.81; p=0.019) in the codominant model; ii) genotypes GT and GG (OR=2.18; 95%CI, 1.26-3.78; p=0.0061) in the dominant model; iii) GT (OR=2.24; 95%CI, 1.28-3.92; p=0.0053) in the overdominant model; iv) the allele G of rs891835 (OR=1.85; 95%CI, 1.14-3.00; p=0.015) in the additive model. In addition, "CG" and "CGGAG" were found by haplotype analysis to be associated with increased GBM risk. In contrast, genotype GG of CCDC26 rs6470745 was associated with decreased GBM risk (OR=0.34; 95%CI, 0.12-1.01; p=0.029) in the recessive model. Conclusions: Our results, combined with those from previous studies, suggest a potential genetic contribution of CCDC26 to GBM progression among Han Chinese.

• Journal of Korean Society for Geospatial Information Science
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• v.21 no.1
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• pp.19-26
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• 2013

This study analyzed the vulnerable areas to the fire service in regard to 119 safety centers, currently established in Jinju city. In this study, the district of fire was examined through the analysis of the OD cost matrix to find the transference or increase methods of the existing centers for improving the fire services. The study results demonstrate that the numbers of 119 safety centers were lacking in comparison with the areas of the administrative district in Jinju. In particular, relocation and the transference or increase of centers were required for the Cheonjeon 119 safety centers, which is the creation area of the National Industrial Complex among five 119 safety centers located in Jinju, and the fire service jurisdiction of Munsan 119 safety centers (including Banseong 119 regional unit), which is the location of a big fire risk due to the increase of population according to the development of the new town. In addition, the OD cost matrix analysis in this study reveals the fact that the time of fire service in the Jeonchon Industrial Complex, which is the significantly vulnerable area, will be reduced from 8 minutes to 3.3 minutes if the current Cheonjeon 119 safety center is moved to Gaho-dong. It indicates that the increase of safety centers in Geumsan-myeon areas, where the population has increased rapidly in recent days due to the development of the new town, is keenly needed.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.10
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• pp.1474-1483
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• 2013

The objective was to evaluate the use of prediction equations based on the chemical composition of feedstuffs to estimate the values of apparent metabolisable energy corrected for nitrogen balance (AMEn) of corn and soybean meal for broilers. For performance and carcass characteristics, 1,200 one-d-old birds (male and female) were allotted to a completely randomised factorial $2{\times}8$ (two genders and eight experimental diets) with three replicates of each sex with 25 birds. In the metabolism trial, 240 eight-d-old birds were distributed in the same design, but with a split plot in time (age of evaluation) with five, four and three birds per plot, respectively, in stages 8 to 21, 22 to 35, and 36 to 42 d of age. The treatments consisted of the use of six equations systems to predict the AMEn content of feedstuffs, tables of food composition and AMEn values obtained by in vivo assay, totalling eight treatments. Means were compared by Scott-Knott test at 5% probability and a confidence interval of 95% was used to check the fit of the energy values of the diets to the requirements of the birds. As a result of this study, the use of prediction equations resulted in better adjustment to the broiler requirements, resulting in better performance and carcass characteristics compared to the use of tables, however, the use of energy values of feedstuffs obtained by in vivo assay is still the most effective. The best equations were: AMEn = 4,021.8-227.55 Ash (for corn) combined with AMEn = -822.33+69.54 CP-45.26 ADF+90.81 EE (for soybean meal); AMEn = 36.21 CP+85.44 EE+37.26 NFE (nitrogen-free extract) (for corn) combined with AMEn = 37.5 CP+46.39 EE+14.9 NFE (for soybean); and AMEn = 4,164.187+51.006 EE-197.663 Ash-35.689 CF-20.593 NDF (for corn and soybean meal).

• Restorative Dentistry and Endodontics
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• v.20 no.1
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• pp.193-213
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• 1995

The purpose of this study is to investigate a possible contribution of nonspecific esterases, which occur in the oral cavity, to the degradation of ester bonds in polymethacrylates. One of the problems connected with the use of composite resins for restorations is their inadequate resistance to wear. It has been shown that methacrylate hydrolysis can be catalyzed by enzymes and that a carboxylic hydrolase (porcine liver esterase) catalyzed the hydrolysis of several mono - and dimethacrylates. The softening effect on a BISGMA/TEGDMA polymer induced by hydrolase will accelerate the in vivo wear of the polymer. Porcine liver esterase (EC 3.1.1.1) 3.2 mol/L $(NH_4)_2$ $SO_4$ was obtained from Sigma Chemical Company. The esterase activity of one unit is defined as the amount of enzyme capable of hydrolyzing $l{\mu}mol$ ethyl butyrate per min at pH 8.0 AT $25^{\circ}C$. Phosphate buffer, 10mmol/L, pH 7.0, was made by adjustment of a solution of $Na_2HPO_4$ with $H_3PO_4$. Composite resins used in this study are Silux Plus, Z-100, Durafil VS, and Prisma APH. Cylindrical specimens, 14mm in diameter and 3mm thick, of Silux Plus, Z-100, Durafil VS, Prisma APH were polymerized under the celluloid strip. 60 specimens were divided into 2 groups. One group was emersed only in buffer solution, the other group was emersed in buffer and enzyme solution. Silux Plus and Z-100 were divided into 2 subgroups, one subgroup was cured only Visilux 2. And the other subgroup was cured Visilux 2 and Triaid II. Thereafter, specimens were polished to its best achievable surface according to manufacture's directions. The Vickers hardness of the specimens was measured after 1, 2, 4, 7, 9, 15, 50 days. The solutions were changed after each measurement. Composite resin surfaces were evaluated for the surface roughness with profilometer (${\alpha}$-step 200, Tencor instruments, USA) after 1 and 50 days. And then surfaces of specimens were pictured with stereosopy after 1 and 50 days. The results were as follows. 1. The surface hardness of Silux plus, durafil VS, and Prisma APH were decreased with time. But, the surface hardness of Z-100 was not decreased. 2. The surface hardness of all composite resins was decreased by esterase. 3. Composite resins, which were light-cured by Visilux 2 and concomitantly baked by oven, showed more hardened surface than light-cured by Visilux 2 only. 4. Significant surface changes were occured in Silux plus after esterase treatment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.518-527
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• 2020

The establishment of a green remodeling strategy is focused on technology, so the necessity of establishing a customized strategy considering the field situation has emerged. This paper examined the technology strategy through sensitivity analysis as a methodology for guiding strategy. For a 90-square-meter detached house, nine models of the construction standards of pre-1980s, 1984, and 2010 in Seoul, Daejeon, and Busan were assessed using the optimization method that combines the energy plus engine and the ModeFrontier. Sensitivity analysis was performed, and the remodeling strategy priority was derived. For pre-1980 models, the strategy for enhancing the roof insulation performance had a significant priority. The SHGC values of the windows were found to have the next highest priority regardless of the region and the time of completion, showing that the performance standard, including the SHGC, needs to be expanded. The possibility of remodeling while maintaining the existing geometry was confirmed because the adjustment of the window wall ratio accompanying large-scale demolition works has low priority. The priorities of technology strategies in each case showed very different patterns, suggesting the possibility of establishing a remodeling strategy by a comprehensive evaluation along with economics and constructability analysis.