• Ocean and Polar Research
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• 제36권2호
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• pp.179-187
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• 2014

Directly searching for undiscovered hydrothermal vent sites is inefficient due to the practical difficulty of comprehensively imaging vent fields. Thus, most searches for hydrothermal vent sites rely on the detection of hydrothermal plumes from water column observation. Detecting and measuring the hydrothermal plumes are the most efficient way to infer the presence and distribution of hydrothermal vents. Both the array of vertical casting and lateral towing are the most common methods to discover hydrothermal plumes. In this study, we compared results of cast and tow-yo operations along the same section of a spreading center with a distance of 20.5 km in the North Fiji Basin for mapping hydrothermal plumes. Operation of CTD tow-yo provides a detailed pattern of plumes which enable us to locate the hydrothermal vents. On the other hand, identification of hydrothermal activity can be determined effectively by CTD cast with additional analysis of geochemical tracers. Reduction in the operating time is another advantage of CTD cast operation, especially for regional-scale survey. Our results show that the combination of CTD cast and tow-yo would improve the efficiency of the hydrothermal plume survey to locate new hydrothermal vent sites.

• International Journal of Oral Biology
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• 제34권2호
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• pp.105-113
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• 2009

Dentin, a major component of teeth, is formed by odontoblasts which produce the dentin matrix beneath the dental epithelium and induce the mineralization of dentin. To date, the biochemical properties of dentin matrix proteins have been well characterized, but upstream regulators of these proteins are not yet well known. Recently in this regard, several transcription factors have been identified as potential regulators of matrix proteins. Most transcription factors are generally involved in diverse biological processes and it is essential to identify those that are odontoblast-specific transactivators to further understand the process of dentin formation. We thus analyzed the expression pattern of dentin matrix proteins and the activities of established transactivators containing a Cre-locus. Expression analyses using in situ hybridization showed that dentin matrix proteins are sequentially expressed in differentiating odontoblasts, including type-I collagen, Dmp-1 and Dspp. The activities of the transactivators were evaluated using ${\beta}$-galactosidase following the generation of double transgenic mice with each transactivator and the ROSA26R reporter line. The ${\beta}$-galactosidase activity of each transactivator paralled the expression of the matrix proteins. These results thus showed that these transactivators could be utilized for odontoblastspecific conditional gene targeting. In addition, time- and tissue-specific conditional gene targeting might also be achieved using a combination of these transactivators. Odontoblast-specific conditional gene targeting with these transactivators will likely also provide new insights into the molecular mechanisms underlying dentin formation.

• 한국운동역학회지
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• 제26권1호
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• pp.135-142
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• 2016

Objective: The purpose of this study was to investigate the acute effect of walking on high heels on the behavior of fascicle length and activation of the lower limb muscles. Methods: Twelve healthy inexperienced high heel wearers (age: $23.1{\pm}2.0yr$, height: $162.4{\pm}4.9cm$, weight: $54.4{\pm}8.5kg$) participated in this study. They walked in high heels (7 cm) and barefoot on a treadmill at their preferred speed. During the gait analysis, the lower limb joint kinematics were obtained using a motion analysis system. In addition, the changes in fascicle length and the level of activation of the medial gastrocnemius (MG) were simultaneously monitored using a real-time ultrasound imaging technique and surface electromyography, respectively. Results: The results of this study show that the MG fascicle operates at a significantly shorter length in high heel walking ($37.64{\pm}8.59mm$ to $43.99{\pm}8.66mm$) in comparison with barefoot walking ($48.26{\pm}9.02mm$ to $53.99{\pm}8.54mm$) (p < .05). In addition, the MG fascicle underwent lengthening during high heel walking with relatively low muscle activation while it remained isometric during barefoot walking with relatively high muscle activation. Conclusion: Wearing high heels alters the operating range of the MG fascicle length and the pattern of muscle activation, suggesting that prolonged wearing of high heels might induce structural alterations of the MG that, in turn, hinder normal functioning of the MG muscle during walking.

• 한국식생활문화학회지
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• 제18권1호
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• pp.1-8
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• 2003

Recently, the concern about safety and functional substances of foods are increased therefore antioxidant substances and plants which had pharmacological effect have been studied actively. It has been known that the mulberry leaf is effective in curing many diseases. Nowaday, the pharmachological effects of mulberry leaves on diabetes mellitus and their usage for many aspects were confirmed. Mulberry leaves are known for effective in prevention of diabetes mellitus, because of specific amino acids and fibers. In this study, methanol, hexane, chlorform, ethyl acetate, and butanol extracts obtained from mulberry leaves were added to soybean oil and they were stored for 30 days at $60{\pm}2^{\circ}C$ and peroxide value(POV) and conjugated diene value(CDV) were measured periodically. Results of this study were obtained as follows; 1. The POV of soybean oil after the addition of each mulberry leaves powder(MLP) extracts generally enhanced as the storage time was prolonged, so the POV of all samples was reached higher than 100meq./kg.oil after 10 days storage without the addition of butanol, methanol, ethylacetate, hexane extracts at 0.1% level. Especially, the POV of soybean oils including butanol extract was 87.35meq/kg.oil after 10 days storage and antioxidant activity of butanol extract was shown to be superior to that of BHT. The pattern of the changes of the CDV of soybean oil after the addition of MLP extracts at 0.02%, 0.05% and 0.1%, respectively, were almost constant during 10 days of storage and then rapidly increased during the rest of experimental periods. During 10 days of storage in case of 0.1% adding level, the antioxidant activities of the butanol extract was superior to that of the each MLP extracts.

• 동아시아식생활학회지
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• 제13권4호
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• pp.284-292
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• 2003

This study was conducted to investigate the changes of dietary attitudes and behaviors in relation to the use of computers of elementary school children in Seoul. The total of 451 elementary school children, consisting of 235 females and 216 males, participated in the study. The result of domestic characteristics, dietary attitudes and behaviors, the level of the use of computers, and health-related symptoms of the subjects were achieved through the questionnaires as follows: The average height, weight, BMI and obesity-index of the participants were 149.0 cm, 42.4 kg, 19.0, -8.6, respectively. Anions subjects, 42.8％ answered their bed times were between 11~12 pm, and 82.4％ answered that they had extracurricular activities. The most desired activity as their leisure was computer works (female: 44.3％, male: 62.5％). 38.4％ of children used the computers for 1~2 hours a day and the most general usage of computers was a computer game (66.1％). The changes in dietary habits of the subjects were such as eating faster(30.2％), having lots of snacks(28.8％), eating anything at hand(26.4％), skipping breakfast due to over-sleeping(18.4％). As changes in life patterns, those in the time managements for watching T.V.(35.3％), reading(35.0％), exercising(31.9％), sleeping(27.5％), relaxing(27.5％) and other hobbies(26.4％) were observed. In conclusion, many children were being affected by the socioeconomic factors changing the environments, especially by the need for the use of computers. The rates of eating alone and skipping breakfast were getting higher in the dietary patterns of elementary school children. We found that the changes in social environments according to the heavy use of the computer were affecting on their dietary pattern. The direction and method of nutrition education had to be established for the proper understanding of the desirable dietary behaviors.

• 한국정보시스템학회:학술대회논문집
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• 한국정보시스템학회 2000년도 추계학술대회
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• pp.1.2-24
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• 2000

본연구에서는 단순신경망의 구조와 특성을 이해하기 위해 신경회로망의 알고리듬을 이론적으로 분석하고 이를 토대로 프로그램을 설계 실행하여 신경망의 학습과정을 실험하였다. 본연구에서 채택한 학습알고리듬은 3계층구조의 역전파알고리듬이며 신경망의 모형은 단순의료전문가시스템모형을 입력치로 채택하였다. 계층수, 노드수, 학습사이클 수, 학습율, 모멘텀항등의 모수를 입력한 실험의 결과는 입력치에 대한 출력이 기대목표와 거의 일치하였다.

• KSBB Journal
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• 제9권2호
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• pp.200-210
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• 1994

Cyclosporin A(Cy A) 생산을 위한 회분식 생물 반응기 실험에서, 고정상세포를 이용함으로써 액상 배양과 비교할 때 생물공정 개선의 가능성이 있음을 제시하였다. 고농도 배지를 생산균주가 지수기 생장단계인 발효개시 후 139시간에 첨가하였을 때, 고정상배양과 액상배양 모두에서, 균주의 재활성 및 재생장으로 인해 CyA의 생산기간이 연장되어, 발효개시 후 250시간까지 최대 CyA 농도를 유지하였다. 반면에 배지의 첨가가 없는 단순 회분식 배양의 경우, 두 경우 모두 정체생장 단계에서 CyA의 생산성이 빠른 속도로 감소하였다. 주목할 점은 고정상 세포의 경우 CyA수율($Y_{p/x}$)이 고농도 배지를 첨가한 후에도 지수기때의 수율의 80%에 이르는 높은 값을 계속 유지할 수 있었으나, 이와는 대조적으로 액상 세포는 단지 58%만을 유지할 수 있었다. 그 결과 고정상배양의 최대 CyA생산성 이 액상배양과 비교하여 약 2배 정도 증가하였다.

• 한국정보시스템학회지:정보시스템연구
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• 제17권3호
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• pp.205-233
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• 2008

This study suggests the dynamic value chain model, that will be able to not only show changing processes to organization's significant capital by integrating an individual, implicit, and explicit knowledge which affect organizational decision making, but also distinguish the key driver for raising organizational competitive power because it makes possible to analyze sensitivity of performance along with decision making alternatives and policy changes from dynamic view by connecting knowledge management capability, knowledge management activity, and relations with organizational performance with specific strategic map. Recently, a lot of organizations show interest in measuring and evaluating their performance synthetically. In organizations taking knowledge management, they introduce effective value chain model like a dynamic balanced scorecard (DBSC), and therefore they can reflect their knowledge management condition as well as show their changes by checking performance of established vision and strategy periodically. Furthermore, they can ask for their inner members' understanding and participation by communicating with and inspiring their members with awareness that members are one of their group, present a base of benchmarking, and offer significant information for later decision making. The BSC has been a successful framework for measuring an organization's performance in various perspectives through translating an organization's vision and strategy into an interrelated set of key performance indicators and specific actions. The BSC, while having significant strengths over traditional performance measurement methods, however, has its own limitations, due to its static nature, such as overlooking two-way causation between performance indicators and neglecting the impact of delayed feedback flowing from the adoption of new strategies or policy changes. To overcome these limitations, this study employs SD, a methodology for understanding complex systems where dynamic feedback among the interrelated system components significantly impact on the system outcomes. The SD simulation model in the form of DBSC would serve as a useful strategic teaming tool for facilitating an organization's communication process through various scenario analyses as well as predicting the dynamic behavior pattern of their key performance measures over a future time frame. For the demonstration purpose, this study applied the DBSC model to Prototype of Korea manufacturing and service firm.

• 한국의상디자인학회지
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• 제10권2호
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• pp.69-78
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• 2008

The purpose of this study is to develop a plan that adopts a fairly tale motif, which is familiar to children, to traditional Korean costume design factors for the development of practical Korean costume enterprises, which lead the Korean costume industry in its existence. Literary research and previous research methods had been used in this study. After comparing traditional Korean costume factors with practical Korean costume factors through literary research, we examined children's Korean costumes and ordinary children costumes. The results of this study are the following: First, the result of literary research, which used traditional Korean costume as motif of practical Korean costume and adopted model factors that the developed motif had used, shows that the design factors of practical Korean Costumes have changed from traditional to modern, seeking practicability and convenience over appearance. Second, practical Korean costumes are suitable when fairy tale illustration is applied to children with curiosity and warm emotions, and towards children, who spend much time on activity during growth. Third, making use of CAD system, which is different from practical Korean costume based on traditional patterns and single color, and using various pint pattern with many stories for the design of practical Korean costumes, and applying diversity to the market of practical Korean costumes, this study provides new design motif from, which people can feel more familiar to practical Korean costumes.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2007년도 정기학술발표대회 논문집
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• pp.416-419
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• 2007

국내의경우, 초기 Cost모델 작성을 위한 비용관련 정보의 축적이 체계적으로 이루어지지 않고, 과거에 수행된 유사 프로젝트의 실적데이터에 대한 정보가 부족해 주 기능 대비 비용에 대한 효용성을 명확히 판단하기 어려워 신뢰할 수 있는 대상선정이 이루어지지 않고 있다. 따라서, 본 연구는 과거 수행된 유사 프로젝트의 비용 정보를 축적, 공유, 활용, 학습할 수 있고, VE활동의 대상선정을 위해 준비단계에서 수행되는 Cost모델의 체계적이고 효율적 분석이 가능한 웹기반 'Cost 모델 분석 시스템(Cost Model Analysis System: CMAS)'의 개념적 모형을 제시하고자 한다. 본 연구에서 제시한 Cost모델 분석 시스템의 개념적 모형을 활용하여 실질적인 시스템이 구축된다면 효과적인 VE 수행을 위한 합리적이고 신뢰성 있는 대상선정이 이루어질 것으로 판단된다.