• Nuclear Medicine and Molecular Imaging
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• v.41 no.3
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• pp.241-246
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• 2007

Purpose: $[^{11}C]6-OH-BTA-1$ ([N-methyl-$^{11}C$]2-(4'-methylaminophenyl)-6-hydroxybenzothiazole, 1), a -amyloid imaging agent for the diagnosis of Alzheimer's disease in PET, can be labeled with higher yield by a simple loop method. During the synthesis of $[^{11}C]1$, we found the formation of by-products in various solvents, e.g., methylethylketone (MEK), cyclohexanone (CHO), diethylketone (DEK), and dimethylformamide (DMF). Materials and Methods: In Automated radiosynthesis module, 1 mg of 4-aminophenyl-6-hydroxybenzothiazole (4) in 100 l of each solvent was reacted with $[^{11}C]methyl$ triflate in HPLC loop at room temperature (RT). The reaction mixture was separated by semi-preparative HPLC. Aliquots eluted at 14.4, 16.3 and 17.6 min were collected and analyzed by analytical HPLC and LC/MS spectrometer. Results: The labeling efficiencies of $[^{11}C]1$ were $86.0{\pm}5.5%$, $59.7{\pm}2.4%$, $29.9{\pm}1.8%$, and $7.6{\pm}0.5%$ in MEK, CHO, DEK and DMF, respectively. The LC/MS spectra of three products eluted at 14.4, 16.3 and 17.6 mins showed m/z peaks at 257.3 (M+1), 257.3 (M+1) and 271.3 (M+1), respectively, indicating their structures as 1, 2-(4'-aminophenyl)-6-methoxybenzothiazole (2) and by-product (3), respectively. Ratios of labeling efficiencies for the three products $([^{11}C]1:[^{11}C]2:[^{11}C]3)$ were $86.0{\pm}5.5%:5.0{\pm}3.4%:1.5{\pm}1.3%$ in MEK, $59.7{\pm}2.4%:4.7{\pm}3.2%:1.3{\pm}0.5%$ in CHO, $9.9{\pm}1.8%:2.0{\pm}0.7%:0.3{\pm}0.1%$ in DEK and $7.6{\pm}0.5%:0.0%:0.0%$ in DMF, respectively. Conclusion: The labeling efficiency of $[^{11}C]1$ was the highest when MEK was used as a reaction solvent. As results of mass spectrometry, 1 and 2 were conformed. 3 was presumed.

• Journal of the Korea Fashion and Costume Design Association
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• v.13 no.1
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• pp.11-20
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• 2011

The yarn company needs to conform to the consumers' sensibility, which has become diverse, in developing its yarn, which fixes the matter property and the sensibility in knit product. In particular, the development of fancy yarn, which is expected to have great influence upon the sensibility of material due to being a diverse form of knit yarn, may increase activation of the knit industry. Eight different fancy yarns were chosen: loop, Ratine, tam tam, fur 1, fur 2, chenille, ladder and tape yarn. The manufacturing methods of these yarns are all different. The sensibility was evaluated through a questionnaire targeting 60 women in their 20s of the expert group. Factor analysis, reliability, correlation analysis, ANOVA, Duncan, and regression analysis were carried out by using SPSS 12.0. First, according to the results of analyzing the sense factor, three factors were extracted: 'inflexibleness/rugged', 'lightweight' and 'smooth'. 'Activity', 'grace' and 'purity' were extracted in regard to the sensibility factor. H3(tam tam) sample showed high value in all of preference, purchase intention and word-of-mouth intention. To increase consumers' preference, purchase intention, and word-of-mouth intention, its effect is thought to be likely to be possibly seen only when increasing the factor of pure and simple grace and when reducing the hard and stiff inflexibleness/ruggedness sense. It is expected to be likely to possibly secure marketability as knit product, which has product competitiveness, given the product planning in a company of producing knit.

• The Research Journal of the Costume Culture
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• v.21 no.6
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• pp.860-876
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• 2013

The pattern cases for Korean traditional socks are named "beoseonbongip" which means a pouch to keep patterns for making "beoseon". "Beoseon" is Korean traditional socks. This study is to identify characteristics of the pattern cases and to develop cultural products based on the unique characteristics of the pattern cases. One hundred fifty one photos of "beosonbongip" were collected and quantitatively and qualitatively analyzed. Seventy percent of them were made between Joseon Dynasty and 1960s. As a result, most of the collected pattern cases are rectangular and square shapes, red color, and silk fabrics, and sizes of them are from 9cm to 15cm. A few pattern cases with different sizes and colors were also observed. Most pattern cases were made by fixing two among four triangle pieces which made by folding four tips of a rectangular or square cloth and then puting a not or a loop on the remaining triangle pieces in order to open and close the pattern cases. In a small number of the pattern cases, three of the four pieces were fixed and a button, a bead, a broach, or two nots or two loops were put on the other piece for opening and closing. Products such as apparels, bags, pouches, frames, and key holders were made using "beoseonbongip" form and construction method. This shows that "beoseonbongip" is a useful motive for creative product development.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.12
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• pp.1637-1643
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• 2011

Korean native chickens are a very valuable chicken population in Korea and their prices are higher than that of commercial broilers. In order to discriminate two commercial Korean native chicken populations (CCP1 and CCP2), single nucleotide polymorphisms (SNPs) from mitochondrial (mt) DNA D-loop sequences and LEI0258 marker polymorphisms in the major histocompatibility complex (MHC) region were investigated. A total of 718 birds from nine populations were sampled and 432 mtDNA sequences were obtained. Of these, two commercial Korean native chicken populations (363 birds) were used for investigation of their genetic relationship and breed differentiation. The sequence data classified the chickens into 20 clades, with the largest number of birds represented in clade 1. Analysis of the clade distribution indicated the genetic diversity and relation among the populations. Based on the mtDNA sequence analysis, three selected SNPs from mtDNA polymorphisms were used for the breed identification. The combination of identification probability (Pi) between CCP1 and CCP2 using SNPs from mtDNA and LEI0258 marker polymorphisms was 86.9% and 86.1%, respectively, indicating the utility of these markers for breed identification. The results will be applicable in designing breeding and conservation strategies for the Korean native chicken populations and also used for the development of breed identification markers.

• Journal of Electrical Engineering and Technology
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• v.11 no.6
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• pp.1664-1673
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• 2016

Lithium rechargeable cells are used in many industrial applications, because they have high energy density and high power density. For an effective use of these lithium cells, it is essential to build a reliable battery management system (BMS). Therefore, the state of charge (SOC) estimation is one of the most important techniques used in the BMS. An appropriate modeling of the battery characteristics and an accurate algorithm to correct the modeling errors in accordance with the simplified model are required for practical SOC estimation. In order to implement these issues, this approach presents the comparative analysis of the SOC estimation performance using equivalent electrical circuit modeling (EECM) and noise suppression technique (NST) in three representative $LiCoO_2/LiFePO_4/LiNiMnCoO_2$ cells extensively applied in electric vehicles (EVs), hybrid electric vehicles (HEVs) and energy storage system (ESS) applications. Depending on the difference between some EECMs according to the number of RC-ladders and NST, the SOC estimation performances based on the extended Kalman filter (EKF) algorithm are compared. Additionally, in order to increase the accuracy of the EECM of the $LiFePO_4$ cell, a minor loop trajectory for proper OCV parameterization is applied to the SOC estimation for the comparison of the performances among the compared to SOC estimation performance.

• Journal of Digital Contents Society
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• v.18 no.6
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• pp.1057-1065
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• 2017

Coding education for elementary school student spreads around the world. Game activity that children like is one of coding education methods. Among these, a board game is a tool where 3~4 children can participate together. This study developed a storytelling-based board game to help elementary school students understand Software education. The board game is composed of board, three types of command cards and dice. This study simultaneously surveyed and interviewed 57 fifth- and sixth-grade students at elementary school after playing the board game 4 times so as to analyze the usefulness of the developed software board game. In the results of study, most of elementary school students would be interested and participated in active. Elementary school students actually got to know algorithm easily through board game activity, and learned basic programming concepts such as sequence, condition, loop, variable and operation.

• Korean Journal of Poultry Science
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• v.45 no.3
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• pp.209-217
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• 2018

The innate immune recognition is based on the detection of microbial products. Toll-like receptors (TLRs) located on the cell surface and the endosome senses microbial components and nucleic acids, respectively. Chicken TLRs mediate immune responses by sensing ligands from pathogens, have been studied as immune adjuvants to increase the efficacy of vaccines. Single nucleotide polymorphisms (SNPs) of TLR3 and TLR4 genes in chicken were associated with resistance and susceptibility to viral infection. In this study, SNPs of chTLR3 and chTLR4 genes were retrieved from public database and annotated with chicken reference genome. Three-dimensional models of the chTLR3 and chTLR4 proteins were built using a Swiss modeler. We identified 35 and 13 nsSNPs in chTLR3 and chTLR4 genes respectively. Sorting Intolerant from Tolerant (SIFT) and Polymorphism Phenotyping v2 (Polyphen-2) analyses, suggested that, out of 35 and 13 nsSNPs, 4 and 2 SNPs were identified to be deleterious in chTLR3 and chTLR4 gene respectively. In chTLR3, 1 deleterious SNP was located in ectodomain and 3 were located in the Toll / IL-1 receptor (TIR) domain. Further structural model of chTLR3-TIR domain suggested that 1 deleterious SNP be present in the B-B loop region, which is important for TIR-TIR domain interactions in the downstream signaling. In chTLR4, the deleterious SNPs were located both in the ectodomain and TIR domain. SNPs predicted for chTLR3 and chTLR4 in this study, might be related to resistance or susceptible to viral infection in chickens. Results from this study will be useful to develop the effective measures in chicken against infectious diseases.

• Journal of Power Electronics
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• v.15 no.5
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• pp.1305-1317
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• 2015

Distributed generation systems (DGSs) have been getting more and more attention in terms of renewable energy use and new generation technologies in the past decades. The self-excited induction generator (SEIG) occupies an important role in the area of energy conversion due to its low cost, robustness and simple control. Unlike synchronous generators, the SEIG has to absorb capacitive reactive power from the outer device aiming to stabilize the terminal voltage at load changes. This paper presents a novel static VAR compensator (SVC) called a magnetic energy recovery switch (MERS) to serve as a voltage controller in SEIG powered DGSs. In addition, many small scale SEIGs, instead of a single large one, are applied and devoted to promote the generation efficiency. To begin with, an expandable mathematic model based on a d-q equivalent circuit is created for parallel SEIGs. The control method of the MERS is further improved with the objective of broadening its operating range and restraining current harmonics by parameter optimization. A hybrid control strategy is developed by taking both of the stand-alone and grid-connected modes into consideration. Then simulation and experiments are carried out in the case of single and double SEIG(s) generation. Finally, the measurement results verify that the proposed DGS with SVC-MERS achieves a better stability and higher feasibility. The major advantages of the mentioned variable reactive power supplier, when compared to the STATCOM, include the adoption of a small DC capacitor, line frequency switching, simple control and less loss.

• BMB Reports
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• v.40 no.4
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• pp.571-576
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• 2007

Three anti-apoptosis genes, Ls-iap2, iap3 and p49 were found in Leucania separata multiple nuclear polyhedrovirus. Amino acid sequence homology of Ls-IAP2 and Ls-IAP3 with Op-IAP2 and Op-IAP3 from Orgyia pseddotsugata MNPV were 20% and 42%, while that of Ls-P49 is 28% with Sl-P49 from Spodoptera littorolis MNPV. Ls-IAP2 contains one baculoviral IAP repeat (BIR) domain followed by a RING domain, while Ls-IAP3 contains two BIRs and a RING. Ls-P49 contains a reactive site loop, predicted cleavage site (KKLD$^{74}{\downarrow}$G) that is different from Sl-P49 (TVID$^{94}{\downarrow}$G). Expressed Ls-iap3 or Ls-p49 under presence of actinomycin D in SF9 cells, DNA ladder assayrevealed that Ls- IAP3 or Ls-P49 could block the apoptosis of SF9 cells induced by actinomycin D. Replication of p35 deficient-mutant Autographa californica MNPV in SF9 cells was also rescued when Ls-iap3 or Ls-p49 was expressed transiently. No anti-apoptotic activity was observed for Ls-IAP2. The results showed that both of Ls-IAP3 and Ls-P49 were functional apoptotic suppressors in SF9 cells.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.11
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• pp.1262-1270
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• 2007

In this paper, we propose a new distortion cancellation mechanism for a balanced power amplifier structure using the carrier cancellation loop of a feedforward and post-distortion technique. The proposed cross post-distortion balanced linear amplifier can reduce nonlinear components as much as the conventional feedforward amplifier through the output dynamic range and broad bandwidth. Also the proposed system provides higher efficiency than the feedforward. The capacities of power amplifier and error power amplifier in the proposed system are analyzed and compared with those of feedforward amplifier. Also the operation mechanisms of the three kind loops are explained. The proposed cross post-distortion balanced linear power amplifier is implemented at the IMT-2000($f_0=2.14\;GHz$) band. With the commercial high power amplifiers of total power of 240 W peak envelope power fer base-station application, the adjacent channel leakage ratio measurement with wideband code division multiple access 4FA signal shows 18.6 dB improvement at an average output power of 40 dBm. The efficiency of fabricated amplifier Improves about 2 % than the conventional feedforward amplifier.