• Anxiety and mood
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• v.15 no.1
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• pp.1-12
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• 2019

Thought-action fusion (TAF) is a tendency to blindly assume causal relations between their thoughts and external reality. On the other hand, cognitive fusion (CF) is a tendency to take internal experiences, such as thoughts and feeling, literally rather than view them as random events. However, these two terms are often confusedly used and, in fact, have conceptual overlaps. Therefore, this study aimed to identify their distinctive features through a comprehensive review of the definition, origin, measurements and clinical implications especially on the understanding of obsessive-compulsive symptoms. The cognitive-behavioral concept of TAF is confined to erroneous and maladaptive beliefs about the connection between thoughts and behaviors. The CF is a broader construct that entails taking thoughts and feelings as facts and engaging or struggling with them such that the quality of life is lowered. They also have different theoretical backgrounds, developing processes and therapeutic approaches. From the perspective of the obsessive-compulsive disorder, both concepts have been studied as mid-structures for this illness. Recently, the effectiveness of psychological therapies related to these concepts such as defusion therapy has been tested. However, it is yet still in its infancy. In the future, complementary advances between the two concepts with studies on biological substrates is needed.

• Molecules and Cells
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• v.25 no.1
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• pp.7-19
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• 2008

Complexins play a critical role in the control of fast synchronous neurotransmitter release. They operate by binding to trimeric SNARE complexes consisting of the vesicle protein Synaptobrevin and the plasma membrane proteins Syntaxin and SNAP-25, which are key executors of membrane fusion reactions. SNARE complex binding by Complexins is thought to stabilize and clamp the SNARE complex in a highly fusogenic state, thereby providing a pool of readily releasable synaptic vesicles that can be released quickly and synchronously in response to an action potential and the concomitant increase in intra-synaptic $Ca^{2+}$ levels. Genetic elimination of Complexins from mammalian neurons causes a strong reduction in evoked neurotransmitter release, and altered Complexin expression levels with consequent deficits in synaptic transmission were suggested to contribute to the etiology or pathogenesis of schizophrenia, Huntington's disease, depression, bipolar disorder, Parkinson's disease, Alzheimer's disease, traumatic brain injury, Wernicke's encephalopathy, and fetal alcohol syndrome. In the present review I provide a summary of available data on the role of altered Complexin expression in brain diseases. On aggregate, the available information indicates that altered Complexin expression levels are unlikely to have a causal role in the etiology of the disorders that they have been implicated in, but that they may contribute to the corresponding symptoms.

• Journal of the Korea Convergence Society
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• v.3 no.1
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• pp.27-34
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• 2012

After Fukushima Nuclear Accident on Mar11, 2011, to grasp the thought of university students in Korea on radiation and medical radiation and seek for the right mass communication on the radiation safety of the people and the proper teaching method on radiation, 790 questionnaires from the universities which had a four-year department of radiological science in 5 provinces(Gyeonggi, Gangwon, Chungcheong, Jeolla, and Gyeongsang-do) all over the country were collected and analyzed. The questionnaire was composed of 36 items, and it was analyzed that one of the important causes that made them feel that radiation was dangerous was 'even if they were exposed to the small quantity of radiation, they could have trouble later.' ($3.28{\pm}1.05$). In the item of the control of radiation, there were the respondents who answered that the government should take action rather than an individual($3.87{\pm}0.89$). In the item of 'Fukushima Nuclear Accident made me think that 'We should not keep nuclear power generation', the result was $2.79{\pm}0.95$. In the item of 'My thought on the medical radiation has negatively changed since Fukushima Nuclear Accident', the students who hadn't taken the course related with radiation showed a negative thought on the medical radiation, such as, there was $2.64{\pm}1.02$ as a whole, $2.31{\pm}1.00$ in department of radiological science, $2.94{\pm}0.95$ in department of dental hygiene, and $3.13{\pm}0.82$ in other departments. And also, those who thought that the education of radiation was necessary were 82.28%, and T.V or Internet was thought as the most effective teaching method.