• Title/Summary/Keyword: Thomas More

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Cardiac Arrest Management in the Workplace: Improving but Not Enough?

  • Alexis Descatha;Francois Morin;Marc Fadel;Thomas Bizouard;Romain Mermillod-Blondin;Julien Turk;Alexandre Armaingaud;Helene Duhem;Dominique Savary
    • Safety and Health at Work
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    • v.14 no.1
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    • pp.131-134
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    • 2023
  • The aim was to describe out-of-hospital cardiac arrest (OHCA) occurring in the workplace of a large emergency network, and compare the evolution of their management in the last 15 years. A retrospective study based on data from the Northern Alps Emergency Network compared characteristics of OHCA between cases in and out the workplace, and between cases occurring from January 2004 to December 2010 and from January 2011 to December 2017. Among the 15,320 OHCA cases included, 320 occurred in the workplace (2.1%). They were more often in younger men, and happened more frequently in an area with access to public defibrillation, had more often a shockable rhythm, had a cardiopulmonary resuscitation started by a bystander more frequently, and had a better outcome. Cardiopulmonary resuscitation started by a bystander was the only chain of survival link that improved for cases occurring after December 2010. Workplace OHCA seems to be managed more effectively than others; however, only a slight survival improvement was observed, suggesting that progress is still needed.

The Effect of Patellar Inferior Gliding on Knee Flexion Range of Motion in Individuals With Rectus Femoris Tightness

  • Kim, Jun-hee;Kim, Moon-hwan;Jeon, In-cheol;Hwang, Ui-jae;Kwon, Oh-yun
    • Physical Therapy Korea
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    • v.23 no.4
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    • pp.1-8
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    • 2016
  • Background: Various methods are used for recovery of knee flexion range of motion (ROM) due to a tightened rectus femoris muscle (RFM) or limited inferior glide of the patella. Stretching methods are common interventions for restoring the tightened RFM length. Also patellar inferior gliding (PIG) technique can recover tightened RFM length too. However, effect of applying the PIG to passive knee flexion (PKF) has not been studied. Objects: The purpose of this study was to investigate the effect of combining PIG with RFM stretching for improving knee flexion ROM in subjects with RFM tightness. Methods: Twenty-six subjects with RFM tightness were recruited. Two different methods of knee stretching were tested: 1) PKF during modified Thomas test (MTT) and 2) PKF with PIG during MTT. The passive stretching forces was controlled by hand-held dynamometer. The knee flexion ROM angle was measured by a MTT with ImageJ software. Differences between the conditions with and without PIG were identified with a paired t-test. Results: The knee flexion ROM was significantly greater for PKF with PIG ($114.44{\pm}9.33$) than for PKF alone ($108.97{\pm}9.42$) (p<.001). Conclusion: A combination of passive knee flexion exercise and PIG can be more effective than PKF in increasing knee flexion ROM in individuals with RFM tightness.

Changed Expression of E-cadherin and Galectin-9 in Oral Squamous Cell Carcinomas but Lack of Potential as Prognostic Markers

  • Chan, Siew Wui;Kallarakkal, Thomas George;Abraham, Mannil Thomas
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2145-2152
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    • 2014
  • Background: The survival rate for oral squamous cell carcinoma (OSCC) has remained generally unchanged in the past three decades, underlining the need for more biomarkers to be developed to aid prognostication and effective management. The prognostic potential of E-cadherin expression in OSCCs has been variable in previous studies while galectin-9 expression has been correlated with improved prognosis in other cancers. The aim of the present study was to investigate the expression of galectin-9 and E-cadherin in OSCC and their potential as prognostic biomarkers. Materials and Methods: E-cadherin and Galectin-9 expression was examined by immunohistochemistry in 32 cases of OSCC of the buccal mucosa (13 with and 19 without lymph node metastasis), as well as 6 samples of reactive lesions and 5 of normal buccal mucosa. Results: The expression of E-cadherin in OSCC was significantly lower than the control tissues but galectin-9 expression was conversely higher. Median E-cadherin HSCOREs between OSCCs positive and negative for nodal metastasis were not significantly different. Mean HSCOREs for galectin-9 in OSCC without lymph node metastasis ($127.7{\pm}81.8$) was higher than OSCC with lymph node metastasis ($97.9{\pm}62.9$) but this difference was not statistically significant. Conclusions: E-cadherin expression is reduced whilst galectin-9 expression is increased in OSCC. However, the present results suggest that E-cadherin and galectin-9 expression may not be useful as prognostic markers for OSCC.

Applications of proportional odds ordinal logistic regression models and continuation ratio models in examining the association of physical inactivity with erectile dysfunction among type 2 diabetic patients

  • Mathew, Anil C.;Siby, Elbin;Tom, Amal;Kumar R, Senthil
    • Korean Journal of Exercise Nutrition
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    • v.25 no.1
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    • pp.30-34
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    • 2021
  • [Purpose] Many studies have observed a high prevalence of erectile dysfunction among individuals performing physical activity in less leisure-time. However, this relationship in patients with type 2 diabetic patients is not well studied. In exposure outcome studies with ordinal outcome variables, investigators often try to make the outcome variable dichotomous and lose information by collapsing categories. Several statistical models have been developed to make full use of all information in ordinal response data, but they have not been widely used in public health research. In this paper, we discuss the application of two statistical models to determine the association of physical inactivity with erectile dysfunction among patients with type 2 diabetes. [Methods] A total of 204 married men aged 20-60 years with a diagnosis of type 2 diabetes at the outpatient unit of the Department of Endocrinology at PSG hospitals during the months of May and June 2019 were studied. We examined the association between physical inactivity and erectile dysfunction using proportional odds ordinal logistic regression models and continuation ratio models. [Results] The proportional odds model revealed that patients with diabetes who perform leisure time physical activity for over 40 minutes per day have reduced odds of erectile dysfunction (odds ratio=0.38) across the severity categories of erectile dysfunction after adjusting for age and duration of diabetes. [Conclusion] The present study suggests that physical inactivity has a negative impact on erectile function. We observed that the simple logistic regression model had only 75% efficiency compared to the proportional odds model used here; hence, more valid estimates were obtained here.

Effects of Bariatric Surgery on Facial Features

  • Papoian, Vardan;Mardirossian, Vartan;Hess, Donald Thomas;Spiegel, Jeffrey H
    • Archives of Plastic Surgery
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    • v.42 no.5
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    • pp.567-571
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    • 2015
  • Background Bariatric surgeries performed in the USA has increased twelve-fold in the past two decades. The effects of rapid weight loss on facial features has not been previously studied. We hypothesized that bariatric surgery will mimic the effects of aging thus giving the patient an older and less attractive appearance. Methods Consecutive patients were enrolled from the bariatric surgical clinic at our institution. Pre and post weight loss photographs were taken and used to generate two surveys. The surveys were distributed through social media to assess the difference between the preoperative and postoperative facial photos, in terms of patients' perceived age and overall attractiveness. 102 respondents completed the first survey and 95 respondents completed the second survey. Results Of the 14 patients, five showed statistically significant change in perceived age (three more likely to be perceived older and two less likely to be perceived older). The patients were assessed to be more attractive postoperatively, which showed statistical significance. Conclusions Weight loss does affect facial aesthetics. Mild weight loss is perceived by survey respondents to give the appearance of a younger but less attractive patient, while substantial weight loss is perceived to give the appearance of an older but more attractive patient.

Characterization of the Fragmentation Pattern of Peptide from Tandem Mass Spectra

  • Ramachandran, Sangeetha;Thomas, Tessamma
    • Mass Spectrometry Letters
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    • v.10 no.2
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    • pp.50-55
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    • 2019
  • The fragmentation statistics of ion trap CID (Collision-Induced Dissociation) spectra using 87,661 tandem mass spectra of doubly charged tryptic peptides are analyzed here. In contrast to the usual method of using intensity information, the frequency of occurrence of fragment ions, with respect to the position of the cleavage site and the residues at these sites is studied in this paper. The analysis shows that the frequency of occurrence of fragment ion peaks is more towards the middle of the peptide than its ends. It was noted that amino acid with an aromatic and basic side chain at N- & C- terminal end of the peptide stimulates more peaks at the lower end of the spectrum. The residue pair effect was shown when the amide bond occurs between acidic and basic residues. The fragmentation at these sites (D/E-H/R/K) stimulates the generation of the y-ion peak. Also, the cleavage site H-H/R/K stimulates the generation of b-ions. K-P environment in the peptide sequence has more tendency to generate y-ions than b-ions. Statistical analysis helps in the visualization of the CID fragmentation pattern. Cleavage pattern along the length of the peptide and the residue pair effects, enhance the knowledge of fragmentation behavior, which is useful for the better interpretation of tandem mass spectra.

A Dream of Communal Society for Parts Without Parts: On Thomas More's Utopia (몫 없는 자들을 위한 공유사회의 꿈: 토머스 모어의 『유토피아』)

  • Lee, Myung-Ho
    • Cross-Cultural Studies
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    • v.45
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    • pp.295-324
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    • 2016
  • This essay attempts a contrapuntal reading of Thomas More's Utopia. Contrapunctual reading, proposed by Edward Said. attempts to make a text speak across temporal, cultural, and ideological boundaries to a topic of present. I examine two opposite readings of Utopia around 2011 by both pro- and anti-Occupy Wall Street positions. On the one hand, the opponents of Occupy find its limits as a utopian social movement echoing in the fictional character of Hythrodaeus and the alternative society verbally sketched by him in Book Two of Utopia. On the other, Occupy's advocates read More's text as embodying its radial possibility. However, each shares the tendency to denounce Book Two, praising Book One in which Hythrodaeus vehemently criticizes England; they read Hythrodaeus not as an utopian idealist but as a social critic. The Occupy, as a result, is seen here as having an ambivalent relationship to utopianism. I reinterpret the radical possibilities of Book Two criticized by both pro- and anti-Occupy invocations of Utopia. Book Two provides a utopian space in which the existing social contradictions are cancelled, revealing the limits of the three partial utopias proposed at the end of Book One. Following Louis Marin's argument, I argue, the "utopic" space does not lie in the so-called ideal society described in the text but in the inconsistencies between the text's description(discourse) and topography(map). In Book Two the existence of a king is described, yet his space is not found in the topography of utopia; likewise market is described as existing at the center of a city, yet its space is not found either. These inconsistencies create a neutral space in which the ideological contradictions of the text are cancelled, and the space opens up the possibility of communal society beyond modern sovereign power and capitalism I argue this utopian dream needs to be summoned once again in our time as a compelling alternative to the corporate, capitalist order.

Iterative identification methods for ill-conditioned processes

  • Lee, Jietae;Cho, Wonhui;Edgar, Thomas F.
    • 제어로봇시스템학회:학술대회논문집
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    • 1997.10a
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    • pp.1762-1765
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    • 1997
  • Some ill-conditioned processes are very sensitive to small element-wise uncertainties arising in classical element-by-element model identifications. For such processes, accurate identification of simgular values and right singular vectors are more important than theose of the elements themselves. Singular values and right singular vectors can be found by iteraive identification methods which implement the input and output transformations iteratively. Methods based on SVD decomposition, QR decomposition and LU decomposition are proposed and compared with the Kuong and Mac Gregor's method. Convergence proofs are given. These SVD and QR mehtods use normal matrices for the transformations which cannot be calculated analytically in general and so they are hoard to apply to dynamic processes, whereas the LU method used simple analyitc transformations and can be directly applied to dynamic processes.

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Recycled Concrete Aggregates: A Review

  • McNeil, Katrina;Kang, Thomas H.K.
    • International Journal of Concrete Structures and Materials
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    • v.7 no.1
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    • pp.61-69
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    • 2013
  • This paper discusses the properties of RCA, the effects of RCA use on concrete material properties, and the large scale impact of RCA on structural members. The review study yielded the following findings in regards to concrete material properties: (1) replacing NA in concrete with RCA decreases the compressive strength, but yields comparable splitting tensile strength; (2) the modulus of rupture for RCA concrete was slightly less than that of conventional concrete, likely due to the weakened the interfacial transition zone from residual mortar; and (3) the modulus of elasticity is also lower than expected, caused by the more ductile aggregate. As far as the structural performance is concerned, beams with RCA did experience greater midspan deflections under a service load and smaller cracking moments. However, structural beams did not seem to be as affected by RCA content as materials tests. Most of all, the ultimate moment was moderately affected by RCA content. All in all, it is confirmed that the use of RCA is likely a viable option for structural use.

SIZE AND ALBEDO PROPERTIES OF MAIN BELT ASTEROIDS BASED ON THE COMPARATIVE STUDY OF INFRARED ASTEROID SURVEYS: IRAS, AKARI, AND WISE

  • Usui, Fumihiko;Hasegawa, Sunao;Ishiguro, Masateru;Muller, Thomas G.;Ootsubo, Takafumi
    • Publications of The Korean Astronomical Society
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    • v.32 no.1
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    • pp.55-57
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    • 2017
  • Presently, the number of known asteroids is more than 710,000. Knowledge of size and albedo is essential in many aspects of asteroid research, such as the chemical composition and mineralogy, the size-frequency distribution of dynamical families, and the relationship between small bodies in the outer solar system or comets. Recently, based on the infrared all-sky survey data obtained by IRAS, AKARI, and WISE, the large asteroid catalogs containing size and albedo data have been constructed. In this paper, we discuss the compositional distribution in the main belt regions based on the compiled data on size, albedo, and separately obtained taxonomic type information.