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Clinical and ultrasonographic studies for the diagnosis of ethylene glycol intoxication in dogs (개의 Ethylene glycol 중독 진단을 위한 임상 및 초음파학적 연구)

  • Byun, Hong-sub;Kim, Myung-cheol
    • Korean Journal of Veterinary Research
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    • v.38 no.3
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    • pp.629-641
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    • 1998
  • This study was performed to evaluate the ultrasonographic findings of ethylene glycol intoxication. Ten healthy mongrel dogs which was administered with ethylene glycol, were evaluated in terms of clinical findings, hematological findings, blood chemistry, and ultrasonographic and histopathological findings of kidney. The results obtained through these experiment could be summarized as follows : 1. Typical clinical symptoms such as vomiting, initial apprehension, depression, thirst, dehydration, tremor, anorexia, hematuria, anuria, weakness, weight loss, flaccid paralysis, tachypnea, coma, and death, were revealed after administration of ethylene glycol. 2. Special symptom of bloody diarrhea was occurred by administration of ethylene glycol. 3. After administration of ethylene glycol, PCV was decreased continuously(p<0.01), and total leukocyte count was increased gradually, revealed the highest value at day 5 and thereafter decreased. 4. Remarkable changes of ultrasonographic findings such as high echo intensity of renal parenchyma and emergence of halo in corticomedullary junction, were revealed after administration of ethylene glycol. Early(hour 8) enlargement and late(day 3) enlargement were observed in kidney(p<0.01). Especially, late enlargement was observed concurrently with the elevation of BUN and creatinine values. 5. Calcium oxalate crystals, metabolites of ethylene glycol, were observed in histopathologic findings of kidney. Also, degeneration and necrotic exfoliation of epithelial cells were recognized in addtion to swelling of renal tubules.

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Saengmaeg-san as an ergogenic aid: improving exercise performance

  • Kwak, Jae-Jun;Yook, Jang Soo;Jeong, Woo-Min;Kim, Ji-Sun;Ha, Min-Seong
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.5
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    • pp.1314-1322
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    • 2020
  • Sports drinks help optimize and improve performance by delaying and eliminating the buildup of fatigue-causing substances in the body during exercise. Saengmaeg-san is a nature-friendly traditional beverage that has no side effects on the human body and can quench thirst. However, studies on the relationship between exercise ability and Saengmaeg-san are insufficient. The purpose of this study was to prescribe Saengmaeg-san during the summer training period of 4 weeks and to analyze the effect on body composition and exercise performance. Seventeen male participants were divided into 3 groups (Saengmaeg-san acid intake group [n=9], placebo group [n=8]), and body composition (height, weight, muscle mass, fat mass, BMI) and conducted exercise performance (total exercise time and HRmax). In our study, Saengmaeg-san intake had a positive effect on exercise performance, such as decreased body fat percentage, increased exercise time, and decreased HRmax. Therefore, Saengmaeg-san showed the potential as a sports drink. In the future, additional studies on fatigue-related substances, immune function-markers, and blood lipids are needed in order to clearly explain the change in exercise performance due to consumption of Saengmaeg-san.

A Study on the I-Ching Perspective in Shanghansuyuanji (『상한소원집(傷寒溯源集)』에 나타난 역학적(易學的) 관점 고찰)

  • Ahn, Jin-hee
    • Journal of Korean Medical classics
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    • v.31 no.3
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    • pp.123-142
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    • 2018
  • Objectives : This paper aims to study the I-Ching perspective in Shanghansuyuanji. Methods : Key words associated with I-Ching was searched in Shanghansuyuanji and analyzed its meaning and categorized thematically. Results & Conclusions : 1. Qianhuang symbolized Shaoyang, The Power of the Great hexagrams, Jueyin Peace hexagrams, Taiyin Gen Earth, Yangming Kun Earth, Shaoyin Return hexagrams, but didn't symbolize Taiyang, making it not uniform. 2. Qianhuang explained physiology focusing the change of YangQi with I-Ching perspective. This is possible because Shanghanlun thought that much of YangQi and I-Ching set a high value on Yang. 3. Qianhuang explained pathology such as insomnia, epigastric fullness, splenic constipation syndrome, Taiyinbing syndrome, somnolence, thirst, YinYang exchange with I-Ching perspective, it is meaningful because it enriches medical YinYanglun. 4. Qianhuang explained prescriptions such as Daqinglongtang, Zhenwutang, Shizaotang, Fuzixiexintang, Dachaihutang, Baihutang, a comparison between Daqinglongtang and Xiaoqinglongtang with I-Ching perspective. This is helpful to grasp the image of prescriptions. 5. Qianhuang explained nature of drugs such as Guizhi, Fuling, Fuzi, Qiandan, Rougui with I-Ching perspective, and it combines well with the features of I-Ching with drugs efficacy. 6. Qianhuang explained diseases of the six Meridians curing time with I-Ching perspective. This shows diseases of the six Meridians recover when Corresponding Qi is vigorous or Conflict Qi appears, and it is persuasive. For reasons mentioned above; Shanghansuyuanji is meaningful as Shanghanlun commentary.

Hypoglycemic effect of Rehmannie Radix Preparata (Sookjihwang) extract in streptozotocin-induced diabetic rats

  • Kang, Shin-Jyung;Bao, Cun Liu;Park, Soo-Jin;Kim, Ae-Jung
    • Nutrition Research and Practice
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    • v.4 no.5
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    • pp.438-442
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    • 2010
  • Rhemannie Radix Preparata (RRP) has been previously employed in traditional oriental medicine as a treatment for diabetic thirst and improving blood flow. The aim of this study was to evaluate its hypoglycemic control by assaying the activities of key enzymes of carbohydrate metabolism in streptozotocin-(STZ)-induced diabetic rats. Further, RRP extracts were prepared in water (RRPW), in 50% ethanol (RRP50), and in 100% ethanol (RRP100), respectively, and compared for their actions in diabetic rats. The oral treatment of RRP (5 mg/kg b.w./d) to diabetic rats for 21 days resulted in a significant decline in blood glucose by 67% compared to diabetic control rats (P < 0.05). The altered activities of glucokinase, glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), and acetyl CoA carboxylase (ACC) in the livers of diabetic rats were reversed significantly to near-normal levels by the administration of RRP (P < 0.05). Among the three RRP extracts, RRP100 was the most effective in terms of hypoglycemic action. However, the administration of RRP to diabetic rats did not improve insulin production. The modulatory effects of RRP100 on the attenuation of carbohydrate enzyme activities appear to hold promise for widespread use for the treatment of diabetes in the future.

The Effect of Sports Drink Containing Schizandra Chinensis on Blood Biochemical Elements, Exercise Performance and HSP70 (오미자를 이용한 스포츠 드링크 섭취가 혈액성분과 운동수행력 및 HSP70에 미치는 영향)

  • 오재근;김복주;신영오;정희정
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.139-150
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    • 2002
  • OBJECTIVES : Schizandra chinensis is well known for its efficacy at liver function reinforcement, relieving thirst and recovery from fatigue. In this study, we examined the effects of sports drink containing Schizandra chinensis on serum metabolic substrate, electrolyte, stress indicators, related-enzyme and exercise performance, rectal temperature, and heat shock proteinb70 (HSP70). METHODS : Elite long-distance runners (male, 21.3yrs, n=16) were selected and divided into two groups; an experimental group (EXP, n=8) and a control group (CON, n=8). A beverage containing Schizandra chinensis was supplemented 3 times per day to EXP for 4 weeks. Serum biochemical elements (glucose, lactate, total cholesterol, triglyceride, high density lipoprotein cholesterol, glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, creatinine, creatine phosphokinase, lactate dehydrogenase, blood urea nitrogen, Na, K, Cl) were analyzed by auto blood analyzer. Exercise performance was measured by treadmill exercise test, HSP70 was detected by electrophoresis and Western blotting, and rectal temperature was measured by rectal temperature probe. RESULTS : Administration of the beverage increased significantly the rest level of blood Na, Cl and glucose and decreased significantly lactate dehydrogenase, glutamate oxaloacetate transaminase. No difference was found in exercise performance, rectal temperature increment or HSP70 concentration between groups. CONCLUSIONS : Administration of a sports drink containing Schizandra chinensis altered blood glucose, lactate dehydrogenase, glutamate oxaloacetate transaminase, Na and Cl levels.

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The Cause of Jeong-Jo's Death Based on The Annals of the Chosun Dynasty (朝鮮王朝實錄), Seungjeongwon Ilgi (承政院日記) (정조의 사망원인에 대한 연구(조선왕조신록과 승전원일기를 중심으로))

  • Kim, Sun-Hyung;Kim, Dal-Rea
    • The Journal of Korean Medicine
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    • v.30 no.4
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    • pp.142-161
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    • 2009
  • Objectives: There are many unknowns surrounding Jeong-Jo's death. To better understand Jeong-Jo's death, we closely inspected his medical records from the 20 days before his death in The Annals of the Chosun Dynasty (朝鮮王朝實錄) and Seungjeongwon Ilgi (承政院日記), Understanding medical treatment before death, we can correctly trace the cause of Jeong-Jo's death. Methods: According to The Annals of the Chosun Dynasty (朝鮮王朝實錄) and Seungjeongwon Ilgi (承政院日記), we examined his medical records between June 14 and June 28 of 1800, as to the change in chief complaint, cold and heat, thirst, syndrome differentiation, the opinions of Jeong-Jo, and the opinions of doctors, The original work, The Annals of the Chosun Dynasty and Seungjeongwon Ilgi were provided by NIKH (The National Institute of Korean History). The Korean translation of The Annals of the Chosun Dynasty was also provided by NIKH. Seungjeongwon Ilgi (original work written in Chinese characters) was directly translated into Korean by the study author. Results: 1. Jeong-Jo's is likely to have died of septicemia caused by an abscess on his back. 2. The cause of Jeong-Jo's death could be stroke due to hypertension, mental stress, and 'Wha (火) disease' Conclusions: The dominant view that Jeong-Jo was murdered by poison is not likely.

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Primary Polydipsia in Children: Two Case Reports

  • Hwang, Nu Ri;Kim, Min Sun;Kim, Soon Chul;Lee, Dae-Yeol
    • Childhood Kidney Diseases
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    • v.22 no.2
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    • pp.67-70
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    • 2018
  • Primary polydipsia (PP) is marked by an increase in thirst, and most often presents in patients with psychiatric illnesses. Although uncommon in children, we experienced cases of PP in a 15-month-old boy and a 5-year-old girl. Both were admitted to the hospital with symptoms of polydipsia and polyuria that appeared 1-3 months before admission. Brain magnetic resonance imaging in both patients was normal. A water restriction test was performed after hospitalization and showed normal results. The symptoms improved after the parents were instructed to implement water-intake restriction for 2 weeks. Our report provides useful information for the treatment of PP in children.

Clinical Study of Moxibustion on The Complication of Diabetes Mellitus (당뇨 합병증에 대한 구치료의 임상적 연구)

  • Lee Hyun Min;Jo Hoon Seuk;Shin Woo Jin;Seu Sang Ho;Park Dong il;Hong Hoon Sang;Kim Jong Won
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.1
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    • pp.294-300
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    • 2004
  • The purpose of this study was to investigate the effects of oxibustion on complications of Diabetes Millitus. We collected 23 patients with glycosurea complications in Songeui Oriental Hospital from April, 2003 to July, 2003, and then expremented Moxibustion, medical examinations and laboratory test for 4 weeks. At the symptons change : Among the symptons which the number over 5 persons of patients is reserved, dysaesthesia of limbs, neuralgic pain, urinary frequent urination, dpontaneous perspiration, thirst, decrease of body weight and malaise showed the improvement over 60%(n=23). Level of FBS was don't have the significant meaning however showed the tendency of the desent, and level of HbA1c significantly decreased after treatment(P&0.001)(n=19).

Study on Effect of Learning Treatment Chart (의안(醫案) 학습효과에 대한 연구)

  • Kim, Yong-Chan;Shin, Hyeun-Kyoo;Kim, Byung-Soo;Kang, Jung-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.3
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    • pp.580-585
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    • 2005
  • Treatment chart(醫案) is a document that doctors have described about their own practice. Western doctor's chart has a prescribed form, but otherwise chart of oriental medicine is a free form. As It has no prescribed form, doctors of oriental medicine have recorded important facts that they think especially. For example, details are patient's name, age, sex and address, the name of disease, state of pulse and tongue, state of secretions(stools, urine, perspiration, etc.), color of face, state of sleep and thirst, diagnosis, prescription, improvement of herb, teaching, and so forth. If we study on chart of oriental medicine, we draw a lesson about practices of a famous doctors. Through that we can increase ability of diagnosis and adaptation to circumstance, make ourselves familiar with use of past prescriptions and way of changing prescription, and learn narrative story of past doctors' personal experience, their though and teaching. As chart of oriental medicine had many methods to take a measure to meet the false situation, we can learn that. Through chart of oriental medicine, we can improve our practice of oriental medicine.

A Study on the Paradigm Shift to Content Management in the Networked Environment (네트웍환경에서 내용관리로의 패러다임 변화에 관한 연구)

  • Nam Tae-Woo;Moon Kyung-Hwa
    • Journal of the Korean Society for Library and Information Science
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    • v.33 no.4
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    • pp.85-111
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    • 1999
  • This study represents an attempt to forecast the increasingly complex and dynamic interplay between the transformation of media and collection management function in the networked environment. As the importance of electronic media rather than printed media is emphasized, there is a need to shift from the traditional collection management to content management for collection development strategy. In order to satisfy the needs of library users who have thirst for more various information, the traditional function of collection management has limitations. Therefore, we suggest that the future collection management must shift from the traditional collection management to content management.

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