• 한국자기학회지
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• 제19권6호
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• pp.203-208
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• 2009

Ka 대역 (26.5~40 GHz)용 전파흡수체의 자성손실재로 Ti-Co가 치환된 M형 바륨 페라이트($BaTi_{0.5}Co_{0.5}Fe_{11}O_{19}$)를 제조하고, 페라이트-고무 복합체에서 자기적 성질 및 전파흡수특성에 관해 조사하였다. M형 바륨 페라이트에서 Ti-Co가 치환됨에 따라 보자력의 감소가 급격히 일어났다. 이는 c 축으로 강한 자기이방성을 갖던 M형 바륨 페라이트의 자기이방성이 a-b 면내 자기이방성으로 변화함에 기인한다. 이에 따라 자연공명주파수를 Ka 주파수 대역으로 이동시킬 수 있었고, 복소투자율의 주파수 분산특성의 제어가 가능하였다. Ti-Co가 치환된 M형 바륨 페라이트 복합체의 경우 Ka 대역에서 임피던스 정합조건을 만족시킬 수 있었다. 흡수대역폭 증가에 페라이트/고무 함량비(F/R)의 조절이 매우 중요함을 제시하였다. F/R = 4의 함량비에서 ?20㏈ 이하의 반사손실을 갖는 흡수대역폭이 7 GHz 정도로 매우 우수한 광대역 전파흡수특성을 보였다. F/R 비가 증가할수록 정합주파수 및 정합두께는 감소하였으나, 흡수대역폭은 줄어들었다.

• The Korean Journal of Physiology and Pharmacology
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• 제18권5호
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• pp.411-418
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• 2014

Vascular remodelling is an adaptive mechanism, which counteracts pressure changes in blood circulation. Nicotine content in cigarette increases the risk of hypertension. The exact relationship between nicotine and vascular remodelling still remain unknown. Current study was aimed to determine the effect of clinically relevant dosage of nicotine (equivalent to light smoker) on aortic reactivity, oxidative stress markers and histomorphological changes. Twelve age-matched male Sprague-Dawley rats were randomly divided into two groups, i.e.: normal saline as control or 0.6 mg/kg nicotine for 28 days (i.p., n=6 per group). On day-29, the rats were sacrificed and the thoracic aorta was dissected immediately for further studies. Mean arterial pressure (MAP) and pulse pressure (PP) of nicotine-treated vs. control were significantly increased (p<0.05). Nicotine-treated group showed significant (p<0.05) increase tunica media thickness, and decrease in lumen diameter, suggesting vascular remodelling which lead to prior hypertension state. The phenylephrine (PE)-induced contractile response in nicotine group was significantly higher than control group ($ED_{50}=1.44{\times}10^5M$ vs. $4.9{\times}10^6M$) (p<0.05~0.001). However, nicotine-treated rat showed significantly lower endothelium-dependent relaxation response to acetylcholine (ACh) than in control group ($ED_{50}=6.17{\times}10^7M$ vs. $2.82{\times}10^7M$) (p<0.05), indicating loss of primary vascular function. Malondialdehyde (MDA), a lipid peroxidation marker was significantly higher in nicotine group. Superoxide dismutase (SOD) enzymatic activity and glutathione (GSH) were all reduced in nicotine group (p<0.05) vs. control, suggesting nicotine induces oxidative imbalance. In short, chronic nicotine administration impaired aortic reactivity, probably via redox imbalance and vascular remodelling mechanism.

• Journal of Acupuncture Research
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• 제18권4호
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• pp.125-142
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• 2001

Objective : The purpose of this study is to observe the effect of Aqua-acupuncture with Stephania Tetrandra Solution (ST-AS) on arthritis. Methods : The author performde several experimental items : that isgene expression and secretion of IL-$1{\beta}$, IL-6, TNF-${\alpha}$, MMP-2, production of ROS, paw thickness, DTH, weight of spleen, expression of CD4+, CD8+, CD19+ in the spleen, production of IL-6, TNF-${\alpha}$, examination of histology. Results : The obstain results are summarized as follows. 1. IL-$1{\beta}$, IL-6, TNF-${\alpha}$ gene expression of hFLS were significantly inhibited in treatmentgroup, and gene expression of MMP-2 was not inhibited in treatmentgroup. 2. The secretion amount of IL-$1{\beta}$, IL-6, TNF-${\alpha}$ were significantly inhibited in treatmentgroup. 3. Expression of P-38 MAP kinase and production of ROS were inhibited in treatmentgroup. 4. Treatmentgroup were significantly inhibited the incidence of arthritis, hind paw edema, the index of arthritis and DTH of CIA (collagen II-induced arthritis) mice. 5. Treatmentgroup were significantly decreased splenetic weight and the number of CD4+, CD8+, CD19+ activated cells and secretion aroout of IL-6, TNF-${\alpha}$ of CIA (collagen II-induced arthritis) mice.. 6. Treatmentgroup were expressed form of new bone, synoviumin, new margine in histology imperison to controlgroup. Conclusions : Taking all these observations into account, ST-AS injection is considered to be effective in treating arthritis and put to practical use in future arthritis clinic.

• Asian-Australasian Journal of Animal Sciences
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• 제23권3호
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• pp.287-291
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• 2010

The purpose of this study was to detect quantitative trait loci (QTL) for growth and carcass quality traits on BTA6 in a population of Hanwoo cattle. Three hundred and sixty one steers were produced from 39 sires that were sired by 17 grandsires in the two Hanwoo farming branches of the National Livestock Research Institute of Korea, between Spring 2000 and Fall 2002. DNA samples were collected for all of the steers, sires and grandsires, and the phenotypes for six growth and carcass quality traits were measured at 24 months of age. Twelve microsatellite markers were chosen on BTA6 and a linkage map was constructed by using seven of the twelve markers. Then, a chromosome-wide QTL scan was performed by applying an Animal Model, in which effects of QTL alleles within the grand sires were fitted as a random term. Three QTL were detected at the 5% chromosome-wise level for backfat thickness, average daily gain, and final weight. The most likely positions for the QTL were in the proximal region, i.e. 0 cM, 35 cM, and 63 cM, respectively. Also, another QTL for longissimus dorsi muscle area was detected at the 10% chromosome-wise level at 67 cM. These results were, in general, consistent with our previous report, in which candidate gene analyses showed that a SNP near ILSTS035 flanked by BM4621 (62.5 cM) and BMS2460 (81.3 cM) was associated with final weight, carcass weight, average daily gain, and longissimus dorsi muscle area in the same Hanwoo population.

• 지질공학
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• 제26권1호
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• pp.23-32
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• 2016

ASTER 위성영상을 이용하여 팽창성 점토광물인 일라이트 인자 추출 및 SVM 통계분석을 통해 산사태 취약성을 평가하였다. 연구지역의 산사태 발생지역은 항공사진 판독 및 현장 조사를 통해 분석하였다. GIS 기반 공간데이터베이스로는 지형도, 토양도, 임상도, ASTER 위성사진을 이용하였다. 수치지형도에서는 경사 및 경사방향, 곡률도, 계곡과의 거리, 도로와의 거리, 토양도에서는 유효토심, 토질, 토양지형, 토양 배수정도 및 토양 모재, 임상도에서는 경급, 영급 및 밀도를 위성사진에서는 일라이트 인자를 추출하였다. 산사태 발생요인 데이터베이스와 SVM 통계분석 및 가중치 계산을 통해 각 요소간의 상관관계 취약성도를 구하였다. AUC 검증 결과 일라이트 인자 적용결과는 76.46%의 예측 정확도를 보였으며 일라이트 인자 미적용 모델은 74.09%의 예측 정확도를 나타내었다. 이는 일라이트 인자가 산사태 취약성도 작성에 있어 중요한 자료로 사용될 수 있음을 나타낸다.

• 자원환경지질
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• 제37권4호
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• pp.425-436
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• 2004

본 연구의 목적은 2002년 태풍 루사로 인해 강릉지역에서 발생한 산사태와 관련 요인들 간의 공간적 관계를 분석하는 것이다. 산사태 위치는 위성영상 및 현지조사를 실시하여 탐지하였다. 지형도, 토양도, 임상도, 지질도, 토지피복도 등을 GIS를 이용하여 공간 데이터베이스로 구축되었고, 이러한 데이터베이스로부터, 경사, 경사방향, 곡률, 수계, 지형 종류, 토질, 토앙모재, 토앙배수, 유효토심, 임상종류, 임상경급, 임상영급, 임상밀도, 암상, 토지피복도, 선구조도 등이 산사태 발생요인으로 이용되었다. 빈도비 모델을 이용하여 산사태와 발생 요인 간의 공간적 관계를 추출하였다. 그 결과인 공간적 상관관계는 2002년 루사로 인한 산사테의 특성을 설명하고, 산사태 취약성도를 작성하는데 이용될 수 있다.

• Journal of Welding and Joining
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• 제6권4호
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• pp.44-53
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• 1988

The mechanical strengths of buried lamellar tears located near the weld toe in the welded tee joints were evaluated in terms of the loss of load carrying capacity as a function of tear area. In static loading, the load carrying capacity was significantly reduced when tear intercepted over 10% of the cross-sectional area of the welded joints. However, the welded joints containing buried tears still failed at stresses over the yield strength of the base metal in the through-thickness direction in spite of the presence of tears up to 20-25% of the area. Fatigue strength of welded joints containing tears markedly reduced with increasing tear areas. Lehigh lamellar tearing test used in this study to produce speicmens was described in detail. The load carrying cpapacity in static loading was influenced by the reduction of supporting area whereas that in fatigue loading was influenced by the stress-concentration effects of lamellar tears and the reduction of supporting area. In bend tests, the pre-existing lamellar tears always grew up toward the weld toe. However, in fatigue loading, cracks grew up and down simultaneously form both the weld toe and the top of lamellar tears because of stress concentration. In fatigue loading, delaminations and decohesion of inclusion/matrix interface generated in multipass welds provided crack propagation paths and enhanced crack propagation because the tips of delaminations and deconhesios acted as stress raisers.

• 한국도로학회논문집
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• 제7권2호
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• pp.87-95
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• 2005

동절기에 대기온도가 영하로 내려감에 따라 포장하부층의 동결 및 응해가 반복되어 포장체의 구조적 성능이 저하된다. 이를 방지하기 위하여 동상에 대한 많은 연구가 수행되었으며, 그 결과, 우리나라 전역의 동결지수선도가 작성되어 동상방지층 설계 등의 도로건설에 이용되고 있다. 하지만, 포장층의 두께와 재료, 그리고 지형에 따른 동결심도의 변화에 대한 조사가 체계적으로 이루어지지 않아 현행 동상방지층 설계의 유효성에 대한 평가가 시급한 실정이다. 본 논문에서는 한국도로공사 시험도로에서 측정되는 대기온도 자료와 콘크리트 및 아스팔트 포장의 깊이별 온도 및 함수량 자료를 이용하여, 시험도로의 동결지수 및 동결가능 깊이를 조사하였다. 또한, 조사된 결과를 기존의 동결심도 추정식에 의한 결과와 비교하였다. 본 연구는 시험도로에서 측정된 동결 관련자료에 대한 초기연구로서 , 장기적인 자료의 축적과 분석을 통하여 보다 신뢰성 있는 결과가 도출될 수 있을 것으로 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• 제20권5호
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• pp.669-676
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• 2007

This study was conducted to detect quantitative trait loci (QTL) affecting growth and body composition in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 18 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between the models were used to characterize QTL for mode of expressions. A total of 8 (39) QTL were detected at the 5% genome (chromosome)-wise level for the 17 analyzed traits. Of the 47 QTL detected, 21 QTL were classified as Mendelian expressed, 13 QTL as paternally expressed, 6 QTL as maternally expressed, and 7 QTL as partially expressed. Of the detected QTL at 5% genome-wise level, two QTL had Mendelian mode of inheritance on SSC6 and SSC9 for backfat thickness and bone weight, respectively, two QTL were maternally expressed for leather weight and front leg weight on SSC6 and SSC12, respectively, one QTL was paternally expressed for birth weight on SSC4, and three QTL were partially expressed for hot carcass weight and rear leg weight on SSC6, and bone weight on SSC13. Many of the Mendelian QTL had a dominant (complete or overdominant) mode of gene action, and only a few of the QTL were primarily additive, which reflects that heterosis for growth is appreciable in a cross between Korean native pig and Landrace. Our results indicate that alternate breed alleles of growth and body composition QTL are segregating between the two breeds, which could be utilized for genetic improvement of growth via marker-assisted selection.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.563-574
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• 2008

Most of earthquake-induced geotechnical hazards have been caused by the site effects relating to the amplification of ground motion, which are strongly influenced by the local geologic conditions such as soil thickness or bedrock depth and soil stiffness. In this study, an integrated GIS-based information system for geotechnical data, called geotechnical information system (GTIS), was constructed to establish a regional counterplan against earthquake-induced hazards at an urban area, Daejeon, which is represented as a hub of research and development in Korea. To build the GTIS for the area of interesting, pre-existing geotechnical data collections were performed across the extended area including the study area and a walk-over site survey was additionally carried out to acquire surface geo-knowledge data. For practical application of the GTIS used to estimate the site effects at the area of interesting, seismic microzoning map of the characteristic site period was created and presented as regional synthetic strategy for earthquake-induced hazards prediction. In addition, seismic zonation for site classification according to the spatial distribution of the site period was also performed to determine the site amplification coefficients for seismic design and seismic performance evaluation at any site in the study area. Based on the case study on seismic zonations at Daejeon, it was verified that the GIS-based GTIS was very useful for the regional prediction of seismic hazards and also the decision support for seismic hazard mitigation.