• The Korean Journal of Pain
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• v.18 no.1
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• pp.1-9
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• 2005

Background: Spinal metabotropic glutamate receptors (mGluRs) and opioid receptors are involved in the modulation of nociception. Although opioid receptors agonists are active for pain, the effects of the compounds for the mGluRs have not been definitely investigated at the spinal level. We examined the effects of the intrathecal mGluR compounds and morphine in the nociceptive test, and then we further clarified the role of the spinal mGluRs. In addition, the nature of the pharmacological interaction after the coadministration of mGluRs compounds with morphine was determined. Methods: Catheters were inserted into the intrathecal space of male SD rats. For the induction of pain, $50{\mu}l$ of 5% formalin solution or a thermal stimulus was applied to the hindpaw. An isobolographic analysis was used for the evaluation of the drug interaction. Results: Neither group I mGluR compounds nor group III mGluR compounds produced any antinociceptive effect in the formalin test. The group II mGluR agonist (APDC) had little effect on the formalin-induced nociception. The group II mGluR antagonist (LY 341495) caused a dose-dependent suppression of the phase 2 flinching response on the formalin test, but it did not reduce the phase 1 response of the formalin test nor did it increase the withdrawal latency of the thermal stimulus. Isobolographic analysis revealed a synergistic interaction after the intrathecal delivery of a LY 341495-morphine mixture. Conclusions: These results suggest that group II mGluRs are involved in the facilitated processing at the spinal level, and the combination of LY 341495 with morphine may be useful to manage the facilitated pain state.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.17 no.11
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• pp.1072-1078
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• 2005

The present study has been conducted to tune a PID controller for large thermal systems such as a thermal environment chamber. In spite of large thermal mass of the thermal chamber under test, its response delay time was found to be negligible mainly due to high air recirculation rate. In general, heating and cooling capacities tend to be small compared the size of a thermal environment chamber, which leads to long transient periods of one hour or so. In the study, a PI tuning method is suggested which makes system responses faster while reducing overshoots and hunting by utilizing efficiently proportional band of actuators.

• Structural Engineering and Mechanics
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• v.16 no.2
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• pp.115-126
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• 2003

A novel finite element model based on the incremental endochronic theory with the effect of temperature was developed in this study to explore the deformed behaviors of a flexible pavement material. Three mesh systems and two loading steps were used in the calculation process for a specimen of three-dimensional circular cylinder. Computational results in the case of an uni-axial compression test for temperatures at $20^{\circ}C$ and at $40^{\circ}C$ were compared with available experimental measurements to verify the ability of developing numerical scheme. The isotropic response and the deviatoric response due to the thermal effect were presented from deformations in different profiles and displacement plots for the entire specimen. The characteristics of changing asphalt concrete material under a specified loading condition might be seen clearly from the numerical results, and might provide an useful information in the field of road engineering.

• Economic and Environmental Geology
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• v.49 no.6
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• pp.459-467
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• 2016

Due to the limited areal space for installation, borehole heat exchangers (BHEs) at depths deeper than 300 m are considered for geothermal heating and cooling in the urban area. The deep vertical closed-loop BHEs are unconventional due to the depth and the range of the typical installation depth is between 100 and 200 m in Korea. The BHE in the study consists of 50A (outer diameter 50 mm, SDR 11) PE U-tube pipe in a 150 mm diameter borehole with the depth of 300 m. In order to compensate the buoyancy caused by the low density of PE pipe ($0.94{\sim}0.96g/cm^3$) in the borehole filled with ground water, 10 weight band sets (4.6 kg/set) were attached to the bottom of U-tube. A thermal response test (TRT) and fundamental basic surveys on the thermophysical characteristics of the ground were conducted. Ground temperature measures around $15^{\circ}C$ from the surface to 100 m, and the geothermal gradient represents $1.9^{\circ}C/100m$ below 100 m. The TRT was conducted for 48 hours with 17.5 kW heat injection, 28.65 l/min at a circulation fluid flow rate indicates an average temperature difference $8.9^{\circ}C$ between inlet and outlet circulation fluid. The estimated thermophysical parameters are 3.0 W/mk of ground thermal conductivity and 0.104 mk/W of borehole thermal resistance. In the stepwise evaluation of TRT, the ground thermal conductivity was calculated at the standard deviation of 0.16 after the initial 13 hours. The sensitivity analysis on the borehole thermal resistance was also conducted with respect to the PE pipe diameter and the thermal conductivity of backfill material. The borehole thermal resistivity slightly decreased with the increase of the two parameters.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.230-234
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• 2000

Thermal comfort by wearing clothes is the important element which gives influence to a clothing comfort. The thermal comfort of clothes have been evaluated by sensory test and physical property of clothes material. To evaluate a thermophysiological comfort. a new evaluation method which measures the physiological response such as electroencephalogram(EEG) is attracting the attention of many people. In the chilly environment, the EEGs in t재 kinds of thermal conditions : with and without clothes were measured. By utilizing the chaos analysis, the behavior of the obtained EEGs were quantiatively expressed in the correlation dimension. As a result, the correlation dimension of the EEGs in being thermal comfortable feeling by putting on clothes, was bigger than the correlation dimension of the EEGs in being cold and discomfort. These results suggest that chaotic analysis of EEG is effective to the quantitative evaluation of thermal esthesis.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.11
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• pp.138-145
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• 2009

A suspended membrane micro fluidic heat flux sensor that is able to measure the heat flow rate was designed and fabricated by a complementary-metal-oxide-semiconductor-compatible process. The combination of a thirty-junction gold and nickel thermoelectric sensor with an ultralow noise preamplifier, low pass filter, and lock-in amp has enabled the resolution of 50 nW power and provides the sensitivity of $11.4\;mV/{\mu}W$. The heater modulation method was used to eliminate low frequency noises from sensor output. It is measured with various heat flux fluid of DI-water to test as micro fluidic application. In order to estimate the heat generation of samples from the output measurement of a micro fluidic heat-flux sensor, a methodology for modeling and simulating electro-thermal behavior in the micro fluidic heat-flux sensor with integrated electronic circuit is presented and validated. The electro-thermal model was constructed by using system dynamics, particularly the bond graph. The electro-thermal system model in which the thermal and the electrical domain are coupled expresses the heat generation of samples converts thermal input to electrical output. The proposed electro-thermal system model shows good agreement with measured output voltage response in transient state and steady-state.

• Journal of the Korean Society of Propulsion Engineers
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• v.27 no.1
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• pp.9-16
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• 2023

This paper investigated the method to predict a thermal response of internal insulation in a solid rocket motor considering both thermal decomposition and ablation. Changes in properties due to the thermal decomposition, swelling of char layer and movement of decomposition gases inside the material were considered during a modeling. And radiative/convective heat flux from the exhaust gas were applied as boundary conditions, while the chemical ablation of the material surface is modeled with algebraic equations. Test SRM with thermocouples was solved for a validation purpose. The results showed that predicted temperatures have identical trends and values compared to the experimental values. And an error of predicted thermal destruction depth was around 0.1 mm.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.9
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• pp.610-619
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• 2011

This paper investigates the simplified comfort index and control logic for VRF (Variable Refrigerant Flow) system by using 3 environmental factors such as temperature, humidity and air flow. Indoor test under thermal load was conducted to explore relationship of each environment factors that is related to simplified comfort index. Simplified comfort function that has 3 environmental variables was proposed based on survey results. Each factor is measured and comfort preference was surveyed by more than 30 subjects in the indoor comfort test. Moreover, control logic for VRF system was developed and then simulated by using thermal load calculation method and verified with test. The proposed comfort function was in good agreement with survey results, and also verification test trend of comfort change and maintenance are quite similar with survey. Furthermore, through the additional test data analysis some differences of comfort according to position of people staying in the test room were additionally investigated by air flow. People being under an exit of air in the indoor air-conditioner feel more comfortable condition and speed of response to comfort change is relatively fast.

• Proceedings of the KSME Conference
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• 2001.06e
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• pp.282-287
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• 2001

The CSCM Upwind method and Material Transport Analysis (MTA) have been used to predict the thermal response and ablation rate for non-charring material to be used as thermal protection material (TPM) in KSR-III test rocket nozzle. The thermal boundary conditions such as cold wall heat-transfer rate and recovery enthalpy for MTA code are obtained from the upwind Navier-Stokes solution procedure. The heat transfer rate and temperature variations at rocket nozzle wall were studied with shape change of the nozzle surface as time goes by. The surface recession was severely occurred at nozzle throat and this affected nozzle performance such as thrust coefficient substantially.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.05a
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• pp.924-927
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• 2007

In this study, adaptation of two-way shape memory effect of SMA wire to the actuator is examined. Therefore the SMA characteristics which are training, material properties, response time at different thermal cycling rates are tested. During training, permanent deformation is accumulated till a certain number of cycle and then saturated. The amount of two-way strain is unchangeable over all cycle and the slope of strain(or stress)-temperature curve is slower as the increase of applied stress. The rate effect is observed resulted from the thermal distribution which heating profile differs from cooling as thermal cycling time. Using the estimated SMA properties, an experimental test for the simple smart wing is performed.