• The Journal of Korean Medicine
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• v.28 no.4
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• pp.124-135
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• 2007

Backgrounds : Scutellaria baicalensis has been used as a medicinal plant to treat various disease conditions accompanying inflammatory response and oxidative stress. Objectives : The aim of this study is to evaluate the effects of Scutellaria baicalensis against inflammatory, pain and edema Methods : In vitro, the effects of Scutellaria baicalensis against lipopolysaccharide-induced inflammation were investigated in mouse BV2 microglial cells. In vivo, the effects of Scutellaria baicalensis on acetic acid-induced writhing response, carrageenan-induced edema and the plantar test (nociceptive thermal stimulation) were investigated using rats and mice. Results : The present results showed that pre-treatment with the aqueous extract of Scutellaria baicalensis suppressed the lipopolysaccharide-stimulated cyclooxygenase-2 expressions in mouse BV2 microglial cells. The aqueous extract of Scutellaria baicalensis inhibited acetic acid-induced abdominal pain in mice and also reduced thermal pain in rats. However, no significant inhibition on carrageenan-induced edema in rats. Conclusions : The present study showed that Scutellaria baicalensis possesses anti-inflammatory and analgesic effects.

• Advances in Traditional Medicine
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• v.9 no.4
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• pp.326-334
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• 2009

The effect of alcoholic extract of Anthocephalus (A.) Cadamba Roxb. was evaluated in experimental models of pain and ulcer. Hot tail flick test, hot plate test and acetic acid induced writhing test were employed for evaluating the peripheral as well as central analgesic mechanism exerted by the extracts. Gastroprotective activity was examined by HCl and ethanol induced gastric damage test. Test group received crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (6.26 ${\pm}$ 0.439 s) which is comparable to diclofenac sodium (6.56 ${\pm}$ 0.381 s) in hot tail flick method. These experimental results also followed the experimental results of hot plate test where crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (4.74 ${\pm}$ 0.234 s) which is comparable to diclofenac sodium (5.58 ${\pm}$ 0.585 s). The crude extract at 500 and 250 mg/kg showed significant reduction in acetic acid induced writhing in mice with a maximum effect of 68.026% reduction at 500 mg/kg dose which is comparable to standard diclofenac sodium (79.93%). In gastroprotective study the extract of A. Cadamba (250 and 500 mg/kg) significantly inhibited ulceration induced by both HCl and ethanol dose dependently. Results of the study suggest that the extract possesses both analgesic and gastroprotective activity on mice.

• Journal of the Korean Society for Geothermal and Hydrothermal Energy
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• v.12 no.4
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• pp.1-7
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• 2016

This paper presents a design method for the horizontal straight ground heat exchanger (GHE) based on the Kavanaugh design method. In order to examine suitability of the suggested design method, a horizontal line type GHE was installed in a steel box of which the size was $5m{\times}1m{\times}1m$ filled with dried Joomunjin standard, and a thermal response test (TRT) was conducted for 21 hours. A numerical analysis was performed for a simulation of a peak month operation and for its verification by finite element method (FEM). According to the simulation results, it was concluded that the suggested design method for a horizontal straight GHE is reliable for the estimation of a design length.

• Journal of Institute of Control, Robotics and Systems
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• v.7 no.7
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• pp.567-573
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• 2001

A real-time HVAC system is proposed which implements real-time control of thermal environment for virtual reality. It consists of a pair of hot and cold loops that serve as thermal reservoirs, and a mixing box to mix hot and cold air streams flowing if from loops. Their flow rates are controlled in real-time to meet a set temperature and flow rate. A cascade control algorithm along with gain scheduling is applied to the system and test results shows that the closed-loop response approached set values within 3 to 4 seconds.

• Nuclear Engineering and Technology
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• v.55 no.6
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• pp.2069-2087
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• 2023

In nuclear power plant (NPP) accidents, the containment is subject to high temperatures and high internal pressures, which may further trigger serious chain accidents such as core meltdown and hydrogen explosion, resulting in a significantly higher accident level. Therefore, studying the mechanical performance of a containment under high temperature and high internal pressure is relevant to the safety of NPPs. Based on similarity principles, the 1:3.2 scale model of a prestressed concrete containment vessel (PCCV) of a NPP was designed. The loading method, which considers the thermal-pressure coupling conditions, was used. The mechanical response of the PCCV was investigated with a simultaneous increase in internal pressure and temperature, and the failure mechanism of the PCCV under thermal-pressure coupling conditions was revealed.

• Journal of the Korean Society for Nondestructive Testing
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• v.36 no.4
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• pp.259-265
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• 2016

This paper presents a study on the use of pulsed phase thermography in the measurement of thermal barrier coating thickness with a numerical simulation. A multilayer heat transfer model was ussed to analyze the surface temperature response acquired from one-sided pulsed thermal imaging. The test sample comprised four layers: the metal substrate, bond coat, thermally grown oxide and the top coat. The finite element software, ANSYS, was used to model and predict the temperature distribution in the test sample under an imposed heat flux on the exterior of the TBC. The phase image was computed with the use of the software MATLAB and Thermofit Pro using a Fourier transform. The relationship between the coating thickness and the corresponding phase angle was then established with the coating thickness being expressed as a function of the phase angle. The method is successfully applied to measure the coating thickness that varied from 0.25 mm to 1.5 mm.

• Journal of the Korean Society of Clothing and Textiles
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• v.44 no.5
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• pp.810-823
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• 2020

This study evaluated the effect of functional characteristics of the fabric for Bikram yoga clothing and fit measured in clothing pressure on the wearer's physiological response and perceptive sensation before and after exercise in hot conditions and during a resting period in standard conditions. The test garment consisted of two tops (T1, T2) and two pants (P1, P2) each with different functional characteristics of fabric. Using various combinations of the test garments, assessment of the thermal sensation and comfort was performed before/after yoga and after resting. This study revealed that thermal sensation and wearing comfort significantly changed based on the functionality of the fabric of top garment before the exercise period. In addition, the results showed that based on clothing pressure, the feeling of comfort was different between before yoga and after resting. The appropriate choice of fabric material was important when constructing Bikram yoga clothing worn in hot conditions; however, level of clothing pressure was also found to be an essential design factor for comfort during rest after exercise.

• Journal of Energy Engineering
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• v.19 no.3
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• pp.143-150
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• 2010

Line source method of borehole system assumes the entire surrounding medium is uniform. However, thermal properties of grouting region are considerably different from those of surrounding soil. In this study we investigate the effect of grouting materials on the solution of line source method with the aid of numerical analysis. This numerical model generates the temperature of borehole fluid with which line source solution can be obtained. Then this solution can be compared with input condition of numerical model. The results of this comparison show that thermal conductivity and borehole thermal resistance of line source solution are approximately 86% and 91% of the input condition of numerical model. Chart method is developed in this study to find the numerical input conditions (thermal conductivity and borehole thermal resistance) from the line source solution. Thermal response test of test borehole is conducted, the results of which are approximately consistent with the Chart method. Thermal property changes of grouting materials on the line source solution are also examined.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.5
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• pp.355-363
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• 2021

Heat resistance performance evaluation and thermal analysis were performed to confirm the applicability of the lyocell-based carbon/phenolic composite material for heat-resistant parts for aerospace. Heat resistance performance evaluation of carbon/phenolic was conducted by Thermal Protection Evaluation Motor (TPEM). In this paper, boundary layer integration code considering the boundary layer analysis of combustion gas and MSC-Marc 2018 considering ablation and thermal pyrolysis were used for the thermal analysis. The ablation and thermal insulation performance were analyzed by the pressure curve of test motor and the cut carbon/phenolic specimens. The thermal response of the lyocell-based carbon/phenolic material was similar to that of the rayon-based carbon/phenolic material. Based on the results through the combustion test, the applicability of heat-resistant parts for aerospace to which domestic lyocell-based carbon fibers were applied was confirmed.

• The Korean Journal of Pain
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• v.18 no.1
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• pp.1-9
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• 2005

Background: Spinal metabotropic glutamate receptors (mGluRs) and opioid receptors are involved in the modulation of nociception. Although opioid receptors agonists are active for pain, the effects of the compounds for the mGluRs have not been definitely investigated at the spinal level. We examined the effects of the intrathecal mGluR compounds and morphine in the nociceptive test, and then we further clarified the role of the spinal mGluRs. In addition, the nature of the pharmacological interaction after the coadministration of mGluRs compounds with morphine was determined. Methods: Catheters were inserted into the intrathecal space of male SD rats. For the induction of pain, $50{\mu}l$ of 5% formalin solution or a thermal stimulus was applied to the hindpaw. An isobolographic analysis was used for the evaluation of the drug interaction. Results: Neither group I mGluR compounds nor group III mGluR compounds produced any antinociceptive effect in the formalin test. The group II mGluR agonist (APDC) had little effect on the formalin-induced nociception. The group II mGluR antagonist (LY 341495) caused a dose-dependent suppression of the phase 2 flinching response on the formalin test, but it did not reduce the phase 1 response of the formalin test nor did it increase the withdrawal latency of the thermal stimulus. Isobolographic analysis revealed a synergistic interaction after the intrathecal delivery of a LY 341495-morphine mixture. Conclusions: These results suggest that group II mGluRs are involved in the facilitated processing at the spinal level, and the combination of LY 341495 with morphine may be useful to manage the facilitated pain state.