• 대한간호
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• 제35권2호
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• pp.52-70
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• 1996

This historical research was conducted to analyze and categorize the titles which were presented in the journal, The Korean Nurse, from August 1962 to October 1995. Titles which were published with the purpose of educating graduate nurses and to update 0 their nursing knowledge to improve professional practice were included. There were 348 articles published from the beginning of publication in August, 1962 to October, 1995. All of the journals were reviewed except nine missing journals which were not available in any library. According to the characteristics of the articles in the periodical, the articles were divided into three periods. In each of the three peroids there were five categories: Subject, Clinical Practice, Fundamentals of Nursing Science, Nursing Administration, Others. These categories were adopted from Kim's(1994) division system which was developed to analyze nurse's insurance education program. The special feature peroid was from August, 1962 to December, 1974. In this period the articles were presented in an unorganized manner in the area of special feature or main issue. The largest area was the subject category(44%). The second largest area wes the fundamental of nursing science category(31%). From May, 1975 to December, 1977, the articles with the educational purposes were published in a designated area called continuing education. This period was labelled as the continuing education period. Among the published articles in this period, 45% focused on the subject category and 45% on the fundamentals of nursing science category. In this period the articles were focusing on nurses 'work in specific areas such as industry, nurses' aid schools, and nursing administration, articles on physical assessment first started to appear. The written continuing education period was from January 1978 to October, 1995. All the educational articles published in this area were analyzed and categorized into five areas as for the other periods. 48% of the articles focused on the subject category. In the mid-eighties, the term nurse specialist first.appeared and ten years later in 1990, the titles were subdivided into more specific titles, such as, home nursing, industrial nursing, emergency nursing, 23% were in the fundamental nursing science category and they dealt with nursing process, nursing theories, theory development. For the content analysis, three articles, one from each period, dealing with cardiovscular diseases were selected for comparsion. First, the special feature period, the title of the article was on diet therapy for cardiovascular disease patients, but instead the content was about rest, hygiene, medication, observation. They recommended rings to prevent bed sores, which is now considered as a cause for bed sores. In the continuing education period, the content was more focused on rehabilitation rather than general nursing .care. It became more specific, systematic, and organized compared with the special feature period. In the written continuing education period, the focus was on rehabilitation, not broadly, but very specifically on exercise. The further research on the content analysis is recommended along with a comparison of the trends in the Journal of Nurses Academic Society.

• Asian Pacific Journal of Cancer Prevention
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• 제15권10호
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• pp.4281-4287
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• 2014

Background: Methylation of tumor suppressor genes has been investigated in all kinds of cancer. Tumor specific epigenetic alterations can be used as a molecular markers of malignancy, which can lead to better diagnosis, prognosis and therapy. Therefore, the aim of this study was to evaluate the association between gene hypermethylation and expression of fragile histidine triad (FHIT), glutathione S-transferase P1 (GSTP1) and p16 genes and various clinicopathologic characteristics in primary non-small cell lung carcinomas (NSCLC). Materials and Methods: The study included 28 primary non-small cell lung carcinomas, where an additional 28 tissue samples taken from apparently normal safety margin surrounding the tumors served as controls. Methylation-specific polymerase chain reaction (MSP) was performed to analyze the methylation status of FHIT, GSTP1 and p16 while their mRNA expression levels were measured using a real-time PCR assay with SYBR Green I. Results: The methylation frequencies of the genes tested in NSCLC specimens were 53.6% for FHIT, 25% for GSTP1, and 0% for p16, and the risk of FHIT hypermethylation increased among patients with NSCLC by 2.88, while the risk of GSTP1 hypermethylation increased by 2.33. Hypermethylation of FHIT gene showed a highly significant correlation with pathologic stage (p<0.01) and a significant correlation with smoking habit and FHIT mRNA expression level (p<0.05). In contrast, no correlation was observed between the methylation of GSTP1 or p16 and smoking habit or any other parameter investigated (p>0.05). Conclusions: Results of the present study suggest that methylation of FHIT is a useful biomarker of biologically aggressive disease in patients with NSCLC. FHIT methylation may play a role in lung cancer later metastatic stages while GSTP1 methylation may rather play a role in the early pathogenesis.

• 한방재활의학과학회지
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• 제23권4호
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• pp.233-250
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• 2013

Objectives The purpose of this study was to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to traffic accident. Methods 1,162 traffic accident patients who were admitted to department of Korean Rehabilitation Medicine of Cheonan Korean Medicine Hospital, Dae-Jeon University from 1st, January, 2011 to 31th, December, 2012 were analyzed according to the medical charts. Results 1. The average treatment result was 3.22 and in most (71.52%) of the patients, symptoms were more than improved. 2. In distribution according to age and sex, people in their 30s numbered the most both in male (12.65%) and female (14.72%). The 1,162 inpatients comprised of 457 (39.33%) male and 705 (60.67%) female. 3. 541 (46.56%) patients admitted in 2011 and 621 (53.44%) patients admitted in 2012. 4. 695 (59.81%) patients visited Cheonan Korean Medicine Hospital within 0~2 days after their traffic accident, followed by 242 (20.83%) patients who visited within 3~5 days after their traffic accident. Patients who admitted earlier showed more improvement in symptoms. 5. The average admission days were 9.32 days. Most (57.66%) patients discharged within 1 week. 6. 825 (71.00%) patients were driving sedan at the time of accident, followed by 105 (9.04%) SUV owners and 71 (6.11%) pedestrians. 7. Rear-end collision accident numbered the most (45.61%), followed by lateral collision (24.35%) and frontal collision (14.72%). 8. Most frequently prescribed examination was X-ray (95.52%), followed by CT (8.69%) and MRI (3.01%). 9. Most frequently given diagnosis was sprain (1,126 (96.90%) patients), followed by concussion & abrasion (178 (15.32%) patients) and fracture (109 (9.38%) patients). 10. Most frequently given Korean medicine treatment was acupuncture (1,162 (100%) patients), followed by anti-inflammatory pharmacopuncture (652 (56.11%) patients) and moxibustion (462 (39.76%) patients). 11. Most frequently given Korean medicine physiotherapy was infra-red (1,161 (99.91%) patients), followed by cupping therapy (1,152 (99.14%) patients) and hotpack (1,137 (97.85%) patients). 12. Most frequently prescribed herb medicine was huishou-san (13.51%), followed by dangguixu-san (12.65%) and yaojiao-tang G (7.06%) Conclusions In this study, people in their 30s, females, within 0~2 days since the accident took the highest percentage from each category of patients who admitted to Korean Medicine Hospital due to traffic accident. Patients who admitted earlier showed more improvement in symptoms and also discharged earlier.

• 인간행동과 음악연구
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• 제16권2호
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• pp.109-132
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• 2019

본 연구에서는 음악을 사용하여 기분을 조절하는 방략이 개인의 감정 경험과 실제로 관련이 있는지 확인하고, 이러한 방략을 사용하는 개인의 경향성이 성격특질, 음악 교육 경험, 성별과 어떤 관계를 갖는지 탐색하였다. 대학생 529명을 대상으로 한국판 음악 사용 기분조절 척도, 성격5요인 척도, 정적/부적 감정 목록, 음악 교육 경험 여부에 관한 설문지를 실시하고 상관분석, 다중회귀분석, 집단 간 평균 차이 검증으로 음악 사용 기분조절 방략과 개인차 변인간의 관계를 탐색하였다. 연구 결과, 음악을 사용하여 기분을 조절하는 것은 부정적인 감정 완화보다는 긍정적인 감정 향상과 더 큰 연관성을 보였으며 평상시의 감정 상태보다는 음악을 감상하고 있을 때의 감정 상태와 더 높은 관련이 있는 것으로 나타났다. 음악 교육을 받은 경우가 받지 않은 경우보다, 여성이 남성보다 유의하게 음악을 사용하여 기분을 조절하는 경향을 보였다. 다중회귀분석 결과, 성격5요인 중 음악 사용 기분조절 방략과 전반적으로 유의한 관계가 있는 특질은 우호성과 경험에 대한 개방성이었으며, 성실성과 신경증 성향은 일부 특정 방략 사용만을 예측하였다. 위의 결과를 통해 음악을 듣는 것이 효과적인 기분조절 방략이며, 부적 감정 완화와 정적 감정 향상 목표를 달성하여 개인의 정서적 안녕감 및 정신건강에 긍정적인 영향을 줄 수 있다는 점과 이러한 효과가 개인 특성에 따라 차별적으로 나타날 수 있다는 것을 알 수 있었다. 마지막으로 연구의 한계점과 후속 연구 제언을 논의하였다.

• Journal of Hospice and Palliative Care
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• 제17권4호
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• pp.270-277
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• 2014

목적: 본 연구는 중등도 이상의 통증을 호소하는 암환자의 통증간호기록을 분석하여 통증의 특성과 통증완화를 위한 중재 및 중재의 효과를 조사하는 후향적 연구이다. 방법: 대상자는 2011년 2월 1일부터 2월 28일까지 서울시에 소재한 C 대학교 병원의 암병동에 입원 환자 중 재원일수가 3일 이상 30일 이하이며, 18세 이상의 성인으로 NRS로 측정한 통증의 강도가 4점 이상인 363명이었다. 결과: 입원 후 4점 이상의 통증을 호소한 건수는 1,394건이었다. 통증의 부위는 복부가 가장 많았고, 통증의 악화요인은 움직였을 때가, 완화요인은 진통제를 투여받았을 때가 가장 많았다. 통증의 유형은 돌발성 통증이 가장 많았다. 통증을 조절하기 위해 사용한 비약물적 중재 중 온요법이 가장 많았다. 약물을 투여하기 전 통증의 강도는 평균 6.68점이었으며 약물투여 후 1시간에 평균 2.81점으로 감소되었다. 정규처방으로 진통제를 투여한 경우는 52.2%였으며, 마약성 진통제 중 Morphine sulfate가, 비마약적 진통제 중 Gabapentin이 가장 많이 사용되었다. 퇴원 시 통증의 강도는 3점 이하가 82.5%였다. 결론: NRS 4점 이상의 통증을 호소하는 암환자는 입원 초기부터 적극적으로 통증을 조절하는 것이 중요하다. 마약성 진통제로 통증을 조절하는 암환자와 가족은 물론 간호사를 대상으로 약제의 효과와 부작용에 대하여 교육하고, 또한 퇴원 후 가정에서 환자와 가족이 통증을 평가하고 기록하여 추후 치료에 반영할 수 있도록 교육하는 것이 필요하다.

• 가정간호학회지
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• 제10권1호
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• pp.15-24
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• 2003

This study provides some basic information on the improvement of diabetics' self-care activities through examining the patients' knowledge on diabetes, self-care activities, and how much they feel those activities are effective and through studying the correlation among the three factors. One hundred and fifty four patients were subjected to this study, who were treated or hospitalized in a hospital in Pusan. Researches were conducted from October 21 to November 9, 2002, and information were gathered by questionnaire and direct conversation with the patients. The data was processed through SPSS WIN 10.0 program. The Date were analyzed by descriptive statistics, ANOVA, t-test, Pearson correlation coefficient and Spearman rank correlation coefficient. The results of this study was the followings; 1) The subjects' knowledge on diabetes ranged from 6 to 23 points with a mean of 17.01 points. 2) The subjects' self-care activities ranged from 21 to 103 points with a mean of 67.72 points. That of the patients with regular treatments appeared to have the highest points (3.51) and the lowest points appeared in the measurement of sugar level in blood (2.60) 3) The subjects' feelings of effectiveness ranged from 21 to 103 points with a mean of 70.01 points. Drug therapy had the highest point (3.94) and diet showed the lowest (3.37) 4) In the general characteristics of the subjects, the more education a subject had, the more knowledge on diabetes he or she appeared to have (F=3.36, p=0.012). The self-care activities were significantly high among non-alcoholic subjects (F=4.301. p=.016). The subjects' feelings of effectiveness were higher in female patients than in male patients(t=2.132 , p=.035), and those in the ages between 51 and 60 felt more effectiveness (F=4.198. p=.003). In addition, married subjects felt more effectiveness than the unmarried (t=2.856, p=0.005), and the more education a patient had. the more effectivess he or she felt (F=2.879, p=.025). 5) In the subjects' pathological characteristic, the subjects who experienced diabetes education showed more knowledge on diabetes, more self-care activity, and more effectiveness than those without the education (t=3.193, p=.002; t=2.299, p=.023; t=2.128, p=.035). 6) As the results of the analyses of correlations among knowledge on diabetes, self-care activity, and effectiveness, the more knowledge on diabetes a patient had, the more self-care activity and the more effectiveness he or she showed (p=0.283. p=0.002; p=0.182, p=0.036). Self-care activity became higher as the feeling of effectiveness appeared higher (r=.550, p=.000). Based on the results above, several suggestions were made; 1) This study was conducted in one hospital, so it is difficult to generalize the results. It is necessary to gather more information from more patients through repeated researches. 2) The study on the other factors which can affect a patient's self-care activity is required. 3) The development of a program which improves a patient's self-care activity, knowledge on diabetes. and effectiveness is needed.

• 사상체질의학회지
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• 제8권2호
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• pp.165-190
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• 1996

동종요법은 1796년 독일인 의사인 S. 하네만에 의해 제창된, 서양의 현대의학과는 다른, 서양의 전통의학이며, 기본 이념은 유기체 내의 자연치유력의 존재를 전제로 하고 있다. 본 연구에서는 먼저 동종요법 기본이론을 서술하고 이에 상당하는 한의학의 기본원리를 비교 고찰함으로써 차후 여러 가지 종류의 자연요법연구에 기초자료를 제공하고, 하네만의 동종요법과 거의 비슷한 연대에 제창된 동무 이제마의 체질의학이 심신(心身), 즉 정신적 상태와 육체적 질병과의 상호 관계성을 언급한 질병관, 약제의 운용정신 등등의 여러 측면에서 그 유사점과 차이점을 비교 고찰하고자 하였다. 1. 동종요법은 생기론(生氣論)과 기계론(機械論)이라는 대립되는 학문적 전승구조로 부터 잉태된 전일의학으로서 서구 현대의학의 골간을 이루는 뉴튼물리학의 기계론적 패러다임과 상위(相違)되며, 그 이론적 성립과 성장배경에서 직 간접적으로 동양학문의 상적 배경과 한의학 이론이 변용된 상태로 흡수된 자연의학(自然醫學)의 일종이다. 2. 동종요법 약제체질론은 약제반응에 따라 질병증상과 개인의 체질적 특성을 직접 일대일 대응시킨 소략한 체질론으로 규율성을 갖춘 체계가 부족하나 심신상관론(心身相關論), 선천적인 체질결정론 등의 기본이론이 사상체질론과 동일하며, 단일 약물에 대한 세심한 개인특성의 연구는 중경입법과 사상의학의 정신에 부합된다고 할 수 있다. 3. 동종요법은 병증의 변화를 체질화하여 선택적 친화성에 따른 약제별로 다양한 유형으로 구분하고, 이에 비하여 사상의학은 병증의 변화를 자신의 체질적 조건하에서 발생하는 체질병증으로 설명하고 있어 차이가 있다.

• 대한한방내과학회지
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• 제22권3호
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• pp.285-290
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• 2001

Purpose : Impaired glucose tolerance (IGT) was standardized in 1979 by the National Diabetes Data Group and the World Health Organization as a risk factor for type 2 diabetes, replacing groups such as 'borderline' and 'chemical' diabetes. The main clinical significance of IGT is as a risk factor for type 2 diabetes and as a risk factor for cardiovascular disease and as a component of the metabolic syndrome. In 1997 the American Diabetes Association(ADA) was proposed the new classification and diagnostic criteria for diabetes, which is strict with the diagnostic baseline of Diabetes from 140mg/dl to 126mg/dl. And it's main purpose is to prevent chronic complications by early diagnosis and treatments. In the oriental medicine, Supungsunkihwan has been used in treatments of Diabetes including IGT & NIDDM, however there is not enough studies about the its objective hypoglycemic effect. so in order to investigate whether there is hypoglycemic effect of Supungsunkihwan, clinical studies were performed with IGT and mild NIDDM patients. Methods : Prior to the study, fasting blood sugar(FBS) and postprandial 2hrs(PP2hrs) glucose were checked. In addition, ECG, cholesterol, TG, HbA1c levels were measured, and the dinical characteristics of patients that can be influence to the blood sugar level such as age, gender, rest type, diet type were surveyed. Supungsukihwan was administered for 7 days, and FBS & PP2hrs were measured again after the therapy. Result : PP2hrs glucose levels were decreased by the administration of Supungsunkihwan. And It's hypoglycemic effects has the correlation with age. That is, the more age increase, the more hypoglycemic effect decrease. Conclusion : Supungsukihwan has hypoglycmic effects on IGT & mild NIDDM patients and it is more effective when administrated to young patients relatively.

• 인간식물환경학회지
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• 제23권3호
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• pp.267-276
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• 2020

Background and objective: Agro-healing is crucial with urban farming in the domestic. It is beyond the conventional agriculture. This study was carried out to assess the 2010s researches on domestic agro-healing and predict the future direction of agro-healing development. Methods: Among the articles published from 2010 to 2018, we collected some articles by searching keywords including agro-healing, garden activity, gardening, horticultural activity, horticultural program, horticultural therapy, plant effect, plant environment, plant growing program, plant impact, social gardening, urban agriculture and vegetable garden activity, selected 83 articles that were evaluated in advance, and analyzed by frequency analysis, t-test, and one-way ANOVA with SPSS 20.0. Results: Agro-healing journal articles were published the most in 2010, and have declined since then. In the classification according to the academic society, most of the journal articles were published by the Society for People, Plants, and Environment. The main targets of domestic agro-healing related to activities and programs were preschoolers, children and adolescents, accounting for 52.4% of the total. By the characteristics of the subjects, agro-healing programs and studies were conducted with special participants who needed special care compared to the general participants. The dependent variables were classified into six areas according to their attributes and the share of psychological and emotional areas was highest (42.6%) among them. In terms of the composition of the program, the share of those with 9-12 sessions was highest (36.7%) and the share of those with more than 20 participants was also highest (39.8%). Conclusion: It is recommended to operate agro-healing programs or industries focusing on the socially disadvantaged including those who have special needs or the underprivileged, but in order to create income for farms and expand the demand for agro-healing, it will be necessary to spread the perception that anyone without any physical or emotional issue can be the targets of and experience agro-healing. To meet the different needs of targets of agro-healing, it will be necessary to conduct objective and practical studies on broader areas and in the process the healing functions of agriculture and the strength of agro-healing needs to be further highlighted.

• Clinical and Experimental Pediatrics
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• 제48권10호
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• pp.1107-1115
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• 2005

목 적 : ESBL 생산 S. sonnei에 의한 장염의 대규모 발생은 과거 국내는 물론 세계에서도 유래를 찾아볼 수 없었다. 저자들은 집단 발생한 ESBL 생산 S. sonnei에 의한 장염 환자의 임상적 특징과 치료에 대한 반응 등을 분석하여 ESBL 생산 S. sonnei 감염증에 대한 치료 지침을 마련하는데 도움이 되고자 한다. 방 법 : 연구 대상은 2004년 11월 충주 ${\bigcirc}{\bigcirc}$초등학교를 중심으로 집단 발생한 급성 장염 환자 중 분변 배양 검사상 S. sonnei가 검출되어 치료받은 환자 103명을 대상으로 하였다. 환자에서 분리된 S. sonnei에 대해 항생제 감수성 검사와 DNA 염기 서열 검사를 시행하였고, 환자들의 임상적 특징과 검사 소견, 그리고 항생제에 대한 반응 등을 후향적으로 분석하였다. 결 과 : 임상 증상은 발열 96.1%, 설사 93.2%, 복통 76.7%, 두통 71.8%, 구토 65.0%, 그리고 구역 41.7% 순으로 나타났다. 발열은 평균 2.0일간 지속되었고, 설사는 평균 3.9일간 지속되었다. 설사의 양상은 수양성 설사는 69%, 점액성 설사는 26%, 그리고 혈변은 5%에서 관찰되었다. 말초 혈액 검사에서 백혈구 증다증을 보이는 경우는 53.4%이었고, 혈청 검사에서 CRP 양성을 보이는 경우는 78.6%이었다. 대변 직접 도말 검사에서 백혈구가 고배율 당 50개 이상인 경우가 11.7%, 그리고 5-20개인 경우 9.7%이었다. 대변 잠혈 반응은 71%에서 양성이었다. 본 유행에서 분리된 ESBL의 유형은 염기 서열을 분석한 결과 CTX-M-14 유형으로 밝혀졌다. 항생제 투여에 대한 미생물학적 치료 결과는 ciprofloxacin 투여자 중 100%(9/9), azithromycin 투여자 중 100%(5/5), cefdinir 투여자 중 6.9%(5/72), ceftriaxone 투여자 중 0%(0/8), ceftizoxime 투여자 중 12.5%(1/8), TMP/SMX 투여자 중 0%(0/8), ampicillin/sulbactam 투여자 중 42.9%(3/7), amoxicillin/clavulanic acid 투여자 중 20%(1/5), 그리고 imipenem/cilastatin 투여자 중 68.8%(11/16)에서 추적 검사상 음전 되었다. 결 론 : 소아에서 발생한 ESBL 생산 S. sonnei에 의한 세균성 이질에 대한 항생제 선택에서 비용-효과 면이나 안전성 면에서 azithromycin이 매력적인 일차 선택약일 수 있을 것으로 사료된다. Ciprofloxacin은 비용-효과 면에서는 우수한 약제일 수는 있으나 소아에서의 사용은 아직 이르다고 생각된다.