• CELLMED
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• v.9 no.4
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• pp.8.1-8.5
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• 2019

Introduction: Psoriasis is a major health concern around the world. Physicians of the Unani system of medicine have been treating psoriasis for centuries. Aim: The purpose of our study was to assess the effect of Majoon Mundi (a semisolid Unani medication intended for oral intake used as blood purifier) and Qairooti Karnab (a Unani medication in paste form intended for topical application used as emollient) in the treatment $na{\ddot{i}}ve$ psoriasis cases and to collect data to warrant further clinical trials. Material and Methods: Psoriasis cases were diagnosed clinically. Data were collected during treatment of five patients of psoriasis treated with the Majoon Mundi (oral intake of 5 gm twice daily with 200 ml of water for 12 weeks) and Qairooti Karnab (topical application on affected sites twice a day for 12 weeks). Patients were treated for 12 weeks. Treatment response was seen with clinical improvement in skin lesions and measurement of Psoriasis Area and Severity Index (PASI Scoring) before and after treatment. Results: Reduced PASI Score was observed in all five patients after 12 weeks of treatment [PASI before and after treatment was (mean${\pm}$SD) $20.7{\pm}4.6$ vs. $3.2{\pm}1.8$; p-value <0.05.]. Clinical improvement was noticed within an average of 4 weeks of treatment. Conclusion: Preliminary findings indicate the potential therapeutic role of Majoon Mundi and Qairooti Karnab in the treatment of psoriasis. Clinical trials based on this Unani pharmacopeial formulation should be conducted to explore the therapeutic potential of this formulation in psoriasis

• Journal of the Korean Applied Science and Technology
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• v.15 no.4
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• pp.11-20
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• 1998

The propagation of light radiation in a turbid medium is an important problem that confronts dosimetry of therapeutic laser delivery and the development of diagnostic spectroscopy. Scattered light is measured as a function of the position(distance r, depth z) between the axis of the incident beam and the detection spot. Turbid sample yields a very forward-directed scattering pattern at short range of position from source to detector, whereas the thicker samples greatly attenuated the on-axis intensity at long range of position. The portions of scattered light reflected from or transmitted throughphantom depend upon internal reflectance and absorption properties of the phantom. Monte Carlo simulation method for modelling light transport in tissue is applied. It uses the photon is moved a distance where it may be scattered, absorbed, propagated, internally reflected, or transmitted out of tissue. The photon is repeatedly moved until it either escape from or is absorbed by the phantom. In order to obtain an optimum therapeutic ratio in phantom material, optimum control the light energy fluence rate is essential. This study is to discuss the physical mechanisms determining the actual light dose in phantom. Permitting a qualitative understanding of the measurements. It may also aid in designing the best model for laser medicine and application of medical engineering.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.2
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• pp.113-125
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• 2018

Exosomes are membranous vesicles of 30-150 nm in diameter that are derived from the exocytosis of the intraluminal vesicles of many cell types including immune cells, stem cells, cardiovascular cells and tumor cells. Exosomes participate in intercellular communication by delivering their contents to recipient cells, with or without direct contact between cells, and thereby influence physiological and pathological processes. They are present in various body fluids and contain proteins, nucleic acids, lipids, and microRNAs that can be transported to surrounding cells. Theragnosis is a concept in next-generation medicine that simultaneously combines accurate diagnostics with therapeutic effects. Molecular components in exosomes have been found to be related to certain diseases and treatment responses, indicating that they may have applications in diagnosis via molecular imaging and biomarker detection. In addition, recent studies have reported that exosomes have immunotherapeutic applications or can act as a drug delivery system for targeted therapies with drugs and biomolecules. In this review, we describe the formation, structure, and physiological roles of exosomes. We also discuss their roles in the pathogenesis and progression of diseases including neurodegenerative diseases, cardiovascular diseases, and cancer. The potential applications of exosomes for theragnostic purposes in various diseases are also discussed. This review summarizes the current knowledge about the physiological and pathological roles of exosomes as well as their diagnostic and therapeutic uses, including emerging exosome-based therapies that could not be applied until now.

• CELLMED
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• v.1 no.1
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• pp.2.1-2.16
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• 2011

Diverse medicinal uses of different types of products obtainable from Brassica juncea have been known for centuries. Most such traditionally known uses of the plant have been centered on its seeds and oils obtainable from them. During more recent decades diverse bio-active molecules and their therapeutically interesting pharmacological properties of its green edible leaves have also been described, and they are now often considered to be effective substitutes for other so called "healthy" Brassica vegetables. However, little concentrated effort has yet been made to obtain a pharmacologically better defined phytopharmaceutical from this easily cultivable plant of commercial interest in many underdeveloped and developing countries. The main aim of this overview is to point out some possibilities for designing and developing such products from the plant for combating the rapidly spreading obesity epidemic in the developed countries and some other countries. Efforts to achieve such goals could as well be an economically more feasible, and culturally more acceptable, starting point for better understanding the potential health benefits of other vegetarian foods.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1106-1109
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• 2002

The analysis on the therapic music of chinese five-sounds studied in order to the stand ardization of the five-sounds. The results were as follows; The central sound of Gung(宮) becomes Do. This music goes on slow speed from first to last and appears the bright, quiet and stable mood. The central sound of Sang(商) becomes Re. This music mainly uses the brass and the fist appears the heavy feeling but gradually becomes ascending mood. The central sound of Kang(角) becomes Mi. This music mainly uses the wood-wind imstrument and appears the most light and vivid feeling. The central sound of Chi(徵) becomes Sol. All instruments sound grandly in the first part, and subsequently sound gentle. The central sound of Woo(羽) becomes La. This music appears dark and tragic mood that is generally used in the minor key. It is played slowly on the whole and appears lyrical feeling in the process of controlling and quiet. In the future, the study on diagnosis and therapy through the standardization of the five-sounds will be continued.

• CELLMED
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• v.9 no.4
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• pp.4.1-4.5
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• 2019

The medicinal plants are extensively used for curing variegated malady in day to day life. There is an emergent demand for plant based medicines, food supplements, health products, pharmaceuticals etc. Mochrus (Bombax ceiba Linn.) is one of the valuable medicinal plants used in Unani system of medicine since relic belongs to family Bombacaceae. It is a tall tree and widely distributed through India, Africa, Australia and tropical Asia. Many parts of the plant (root, stem bark, gum, leaf, prickles, flower, fruit, seed and heartwood) are used for the treatment of a variety of ailments. It is reported to possess nafe sailanur reham (beneficial in leucorrhea), mujaffif (siccative), muqawwi reham (uterine tonic), qabiz (constipative), muallide mani (production of semen), mumsik wa mughalliz mani (increase consistency of semen), dafe fasaad khoon wa safra (purifies blood and bile) etc. It is used in asthma, diarrhoea, wound, leprosy, boils and many other skin diseases. Also possess some important pharmacological activities such as antioxidant, analgesic, antipyretic, antibacterial, diuretic, hepatoprotective, anticancer, hypoglycaemic and hypotensive etc. It is reported to contain phytoconstituents like polysaccharides, naphthoquinones, anthocyanins, lupeol and naphthol etc. This paper provides a compendium review on pharmacological, phytochemical properties and therapeutic benefits of the plant.

• Journal of Dental Anesthesia and Pain Medicine
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• v.19 no.1
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• pp.11-19
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• 2019

Hyaluronic acid (HA) has long been studied in diverse applications. It is a naturally occurring linear polysaccharide in a family of unbranched glycosaminoglycans, which consists of repeating di-saccharide units of N-acetyl-D-glucosamine and D-glucuronic acid. It is almost ubiquitous in humans and other vertebrates, where it participates in many key processes, including cell signaling, tissue regeneration, wound healing, morphogenesis, matrix organization, and pathobiology. HA is biocompatible, biodegradable, muco-adhesive, hygroscopic, and viscoelastic. These unique physico-chemical properties have been exploited for several medicinal purposes, including recent uses in the adjuvant treatment for chronic inflammatory disease and to reduce pain and accelerate healing after third molar intervention. This review focuses on the post-operative effect of HA after third molar intervention along with its various physio-chemical, biochemical, and pharmaco-therapeutic uses.

• Journal of Society of Preventive Korean Medicine
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• v.11 no.1
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• pp.35-44
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• 2007

Recently, Despite improvements of therapeutic methods on malignancy, the need of modalities on the treatment of cancer have been increasing nowadays and Traditional Oriental Medicine have been considered as alternatives and the uses of it have continued to increase in cancer therapy. The aims of this paper is to analysis of approach modality of experts for the research and treatment on cancer and study of clinical research methodology in Korean Medicine.

• International Journal of Contents
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• v.6 no.1
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• pp.53-58
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• 2010

This study details the neuroscientific concept of somatosensation, general sensory stimulation therapy and virtual reality therapy. Somatosensation is a method that the human body uses to accept information from the inner and outer parts of the body. A traditional sensory stimulation therapy was designed to maximize neural recovery, but the neural recovery is most effective when the therapeutic environment is similar to real life. The virtual reality provides natural environment that users may perceive as meaningful and even participants with significant impairment can perform some of the activities of their daily lives within the virtual environment. The virtual reality will become a complementary part of somatosensory rehabilitation.

• Journal of Korean Physical Therapy Science
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• v.12 no.3
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• pp.7-12
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• 2005

Constraint-induce therapy(CIT) has been documented to improve motor function in the upper extremity of people with hemiparesis. The exercise program uses the training technique 'shaping'. Shaping involves repetitive exercise that are progressed in small steps, where only positive feedback is given to the patients. It involves 14 days of using a restraint on the unaffected arm after stroke for 90% of waking hours. In conjunction with this, ten days of intensive exercise with the affected arm are undertaken for around six hour daily. CIT produces great improvement of motor function with a period of 2 weeks, that the treatment effect remains stable for many months after the end of therapy, and that it transfers into the everyday lives of patients. The purpose of this study is to introduce about the principles of CIT charactieristic, techniques, therapeutic effects-throughout reference books.