• 한국시스템다이내믹스연구
• /
• 제17권3호
• /
• pp.121-143
• /
• 2016

The purpose of this study to analyze the effect of Mindfulness on the Therapeutic Relationship using System Dynamics. The biggest factor in psychotherapy's treatment outcome is the Therapeutic Relationship including the quality of the therapist (empathy, therapeutic presence) and therapy alliance. Mindfulness practice can facilitate the therapeutic relationship. In order to analyze the therapeutic relationship, I measure FFMQ(Five Facet Mindfulness Questionnaire), Empathy, Therapeutic presence and Therapy alliance. Participants consist of 55 mental health professionals (doctor, psychologist, psychiatrist, counselor, social worker). The result of the study will be explained. First, with the causal loop diagram research, I analyze how mindfulness can influence the quality of therapist and therapy alliance. The result of literature research indicate that mindfulness increase therapist's empathy, congruence, therapeutic presence, flow, therapy alliance. And then mindfulness reinforces the ability of therapeutic relationship. Secondly, through the real data research and simulation analysis, mindfulness practicing period (year and hour a day) of therapist is studied. The result of the therapist experiencing mindfulness practice period is over 5 years and the daily hours of practice is 2 - 2.5 hours in order to enhance the therapeutic relationship. After reviewing the result of the research it is important to understand the practicing period and daily practice of mindfulness. With daily practice and time, the level of mindfulness will increase and influence positively the therapeutic relationship between therapist and client.

• Physical Therapy Rehabilitation Science
• /
• 제2권1호
• /
• pp.21-26
• /
• 2013

Objective: The aim of this study was to investigate the effect of therapeutic ultrasound (US) of cell viability and inflammatory cytokine in rat articular chondrocyte cultures stimulated with lipopolysaccharide (LPS). Design: One group pretest-posttest design. Methods: Cultured chondrocytes were treated with US and/or LPS and assessed for viability, Tumor necrosis factor $(TNF)-{\alpha}$ and Interleukin (IL)-1 production. Results: Oxidative stress was induced in rat chondrocytes with LPS. The cell viability was decreased in chondrocytes after treatment with LPS. The viability revealed that low-intensity pulsed ultrasound (LIPUS) exerted no significant cytotoxicity in the rat chondrocyte. LIPUS inhibited decreased cell viability in the presence of LPS ($30{\mu}g/ml$) in a intensity dependent pattern at LIPUS (p<0.05). $TNF-{\alpha}$ production in the presence of LPS was also inhibited in a dose dependent manner (p<0.05 from $30mW/cm^2$). IL-1 production in the presence of LPS was inhibited as well (p<0.05 from $7.5mW/cm^2$). Conclusions: Our results demonstrate that US was the anti-inflammatory effect of chondrocytes. LIPUS may exert its anti inflammatory effects through inhibition of $TNF-{\alpha}$ and IL-1 synthesis. These results suggest that US have potential for use as a pain relief and reduce the articular destruction.

• 한국치위생학회지
• /
• 제12권6호
• /
• pp.1232-1240
• /
• 2012

Objectives : In this study, the treatment method for some college students, due to the misuse of non-therapeutic molding technique non-therapeutic procedure is applied in orthodontics or jaw surgery and therapeutic purposes, such as to properly recognize and to investigate whether. Methods : In this study used, 4 questions, the questionnaire general characteristics (such as gender, major, whether the treatment experience and purpose) Orthodontic and knowledge about the jaw surgery (Corrective jaw surgery hope and reason, or jaw surgery benefits, side effects, etc.) 6 items, calibration and recognition jaw surgery on seven items 17 items was constructed. Results : Of the perception of the majors of the respondents according to the presence or absence of a non-therapeutic procedure for calibration or jaw surgery the correct way, and the purpose appeared to know roughly majors and all students majoring statistically significant (p<.001). The degree of recognition for non-therapeutic procedures according to the gender of the respondents' facial aesthetic improvement, and the most common reason, you want to make a non-therapeutic procedure, correction or contrast, I've found that looks supremacist influence on the non-therapeutic procedure or roughly know the correct way, and jaw surgery for the purpose that appeared to be statistically significant (p<.05). Conclusions : Non-therapeutic procedure for the interest and knowledge to promote oral health as well as esthetic improvements to the original non-therapeutic procedure for therapeutic purposes and how to deliver education and it is very important.

• Korean Journal of Radiology
• /
• 제24권7호
• /
• pp.640-646
• /
• 2023

Objective: Prospective studies on postoperative residual breast tissue (RBT) after robotic-assisted nipple-sparing mastectomy (R-NSM) for breast cancer are limited. RBT presents an unknown risk of local recurrence or the development of new cancer after curative or risk-reducing mastectomies. This study investigated the technical feasibility of using magnetic resonance imaging (MRI) to evaluate RBT after R-NSM in women with breast cancer. Materials and Methods: In this prospective pilot study, 105 patients, who underwent R-NSM for breast cancer at Changhua Christian Hospital between March 2017 and May 2022, were subjected to postoperative breast MRI to evaluate the presence and location of RBT. The postoperative MRI scans of 43 patients (age, 47.8 ± 8.5 years), with existing preoperative MRI scans, were evaluated for the presence and location of RBT. In total, 54 R-NSM procedures were performed. In parallel, we reviewed the literature on RBT after nipple-sparing mastectomy, considering its prevalence. Results: RBT was detected in 7 (13.0%) of the 54 mastectomies (6 of the 48 therapeutic mastectomies and 1 of the 6 prophylactic mastectomies). The most common location for RBT was behind the nipple-areolar complex (5 of 7 [71.4%]). Another RBT was found in the upper inner quadrant (2 of 7 [28.6%]). Among the six patients who underwent RBT after therapeutic mastectomies, one patient developed a local recurrence of the skin flap. The other five patients with RBT after therapeutic mastectomies remained disease-free. Conclusion: R-NSM, a surgical innovation, does not seem to increase the prevalence of RBT, and breast MRI showed feasibility as a noninvasive imaging tool for evaluating the presence and location of RBT.

• 대한간호학회지
• /
• 제37권7호
• /
• pp.1027-1038
• /
• 2007

Purpose: The purpose of this study was to identify the effects of a nurse presence program on suicide prevention for elders with chronic disease. Method: The subjects were recruited from two different elderly institutions located in D city and K province, Korea. Twenty subjects in the control group received no intervention and nineteen subjects in the experimental group received a nurse presence program. Result: There were more significant decreases in suicide ideation, and the cortisol level and increases in life satisfaction in the experimental group compared to the control group. Conclusion: According to the above results, a nurse presence program for elders with a chronic disease decreased stressful events like suicide ideation and increased self esteem through therapeutic interaction. These findings suggest that this program can be used as an efficient independent nursing intervention for elders in a critical situation.

• Investigative Magnetic Resonance Imaging
• /
• 제25권4호
• /
• pp.218-228
• /
• 2021

Due to their high degree of freedom to transfer and acquire light, fiber optics can be used in the presence of strong magnetic fields. Hence, optical sensing and imaging based on fiber optics can be integrated with magnetic resonance imaging (MRI) diagnostic systems to acquire valuable information on biological tissues and organs based on a magnetic field. In this article, we explored the combination of MRI and optical sensing/imaging techniques by classifying them into the following topics: 1) functional near-infrared spectroscopy with functional MRI for brain studies and brain disease diagnoses, 2) integration of fiber-optic molecular imaging and optogenetic stimulation with MRI, and 3) optical therapeutic applications with an MRI guidance system. Through these investigations, we believe that a combination of MRI and optical sensing/imaging techniques can be employed as both research methods for multidisciplinary studies and clinical diagnostic/therapeutic devices.

• 생물정신의학
• /
• 제12권2호
• /
• pp.107-113
• /
• 2005

Purpose:In an attempt to predict the interpersonal differences of therapeutic response to antipsychotic drugs on pharmaco-genetic bases, this study was designed to investigate the relationship between the therapeutic response to antipsychotic drugs and Taq I A dopamine $D_2$ receptor polymorphism in schizophrenic patients. Methods:The subjects were 158 patients diagnosed with schizophrenia(DSM-IV). The therapeutic response to antipsychotic drugs was evaluated using the Treatment Response Scale(TRS) retrospectively. Patients were divided into two groups, dopamine receptor antagonist responders, and serotonin-dopamine antagonist responders. The patients' Taq I A dopamine $D_2$ receptor polymorphism was determined by polymerase chain reaction(PCR) and restriction fragment length polymorphism(RFLP). Results:The dopamine receptor antagonist responders had the A1 allele in significantly higher incidences (${\chi}^2$(1)=4.875, p=0.027, two-tailed). No significant difference was found among the serotonin-dopamine antagonist responders between those with or without the A1 allele. Conclusions:The patients with the A1 allele responded better to dopamine receptor antagonists than those with no A1 allele. Based on these results, it is suggested that the pharmacological effect of dopamine receptor antagonists can be predicted depending on the presence of the A1 allele in schizophrenic patients.

• 대한간호학회지
• /
• 제30권1호
• /
• pp.225-239
• /
• 2000

This study is a research of conceptual development to find the factors of presence. The concept and the definition of presence received from literary review. On the basis of these findings, we formulate the contents of presence through structured interview guide composed of open-ended questionnaire which included the frequency, attitude, and posture. We selected 104 samples who are the patients, doctors, nurses, and other health providers. And then the contents of presence were established after integrating the formulated contents and putting them in order. The categorizing of the presence was made after discussing with specialist in this field. By using the selected contents, we made 25 statements of presence which were categorized into three factors. The results were as follows: 1. The definition of presence is being with at the same time and space, making attention with openness, and the therapeutic interaction with empathy. 2. The contents of presence through personal interviews are The time required is 5 minutes(46.15%), 2-3 minutes(34.61%), and 10 minutes (15.38%) respectively. The frequency of visiting is 3 times(39.20%), every time(23.07%), and more than 5 times(20.19%) respectively. \circled2 In case of being with nurse is having pain(39.42%), suffering trouble or severe fear(9.61%), feeling discomfort(8.65%), taking care of wound(7.69%), and other unfavorable symptoms(6.73%) respectively. \circled3 The posture being with nurse is depends on the situations(63.46%), sitting(26.92%), and standing(9.61%) respectively. Eye contact with nurse is face to face(78.84%), depends on the situations(20.19%), and not face to face(0.96%) respectively. \circled4 The attitudes of comfort are explaining about disease(23.07%), holding on hands (14.42%), touching on the suffering parts (11.53%), and unconditionally being with(7.69%) respectively. \circled5 Nurses' caring actions are kindness (27.88%), replying to the question (12.50%), smiling(10.57%), bright appearances (8.65%), and right and quick treatment(8.65%) respectively. \circled6 The effects of being with are peaceful mind(58.65%), quick recovery(13.46%), and decrease in fear(12.50%) respectively. \circled7 The attitudes of being with are listening (11.53%), recognition(8.65%), talking about discomfort(8.65%), and answering kindly (7.69%) respectively. 3. From the analysis of presence factors, 25 statements and 3 categorized factors are presented.

• Journal of Digestive Cancer Research
• /
• 제3권1호
• /
• pp.5-10
• /
• 2015

With advances in the understanding of the biology and genetics of colorectal cancer (CRC), diagnostic biomarkers that may predict the existence or future presence of cancer or a hereditary condition, and prognostic and treatment biomarkers that may direct the approach to therapy have been developed. Biomarkers can be ascertained and assayed from any tissue that may demonstrate the diagnostic or prognostic value, including from blood cells, epithelial cells via buccal swab, fresh or archival cancer tissue, as well as from cells shed into fecal material. For CRC, current examples of biomarkers for screening and surveillance include germline testing for suspected hereditary CRC syndromes, and stool DNA tests for screening average at-risk patients. Molecular biomarkers for CRC that may alter patient care and treatment include the presence or absence of microsatellite instability, the presence or absence of mutant KRAS, BRAF or PIK3CA, and the level of expression of 15-PGDH in the colorectal mucosa. Molecularly targeted therapies and some general therapeutic approaches rely on biomarker information. Additional novel biomarkers are on the horizon that will undoubtedly further the approach to precision or individualized medicine.

• 대한한방내과학회지
• /
• 제39권4호
• /
• pp.772-783
• /
• 2018

The aims of this study were to use the Rydoraku test, electrogastrography, and enterotachography to examine the presence of familial gastric dysmotility among monozygotic twins and their mothers; to determine the relationship between the symptoms and the indexes of the Rydoraku test, electrogastrography, and enterotachography; and to observe the therapeutic reaction for each differential treatment between twins with familial gastric dysmotility. The same herbal medication (Banhasasim-tang extract three times/day and Sojuckkunbi-tang extract three times/day) was given to each twin, but the younger twin also underwent manual acupuncture on the CV 10, 12, and 13 points of the abdominal wall and electrical stimulation of both ST 36 points of the lower leg 2-3 times per week. Evaluation of the therapeutic effect was followed after six weeks. The presence of familial gastric dysmotility was shown in the autonomic nerve system and gastric muscle and was thought to be a common pathophysiology induced by genetic co-ownership. Only the younger twin showed any marked relief of the dyspeptic symptoms associated with improvement of pyloric sphincter function, which was induced by acupuncture treatment. The Rydoraku test, electrogastrography, and enterotachography results showed the presence of familial gastric dysmotility. Although Korean traditional medicine had no effect on the familiar gastric dysmotility associated with genetic influences, the acupuncture treatment had a beneficial effect on the secondary disorder of pyloric sphincter function, which is associated with the relief of dyspeptic symptoms.