• Archives of Pharmacal Research
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• 제26권10호
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• pp.821-825
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• 2003

The effects of purple sweet potato anthocyanin (SPA) and Cordyceps mushroom extract (CME) on lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and cognitive deficits were examined. Both SPA and CME exhibited DPPH radical scavenging activities with similar potency. In contrast, only SPA was shown to effectively inhibit lipid peroxidation initiated by $Fe^{2+}$ and ascorbic acid in rat brain homogenates. Furthermore, SPA markedly enhanced cognitive performance, assessed by passive avoidance test in ethanol-treated mice. Combined treatments with SPA and CME did not significantly influence the effects of SPA alone. These results demonstrate that anthocyanin prepared from purple sweet potato exhibits memory enhancing effects, which may be associated with its antioxidant properties.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2002년도 가을 학술발표논문집 Vol.29 No.2 (2)
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• pp.4-6
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• 2002

최근 소프트웨어 산업에서는 개발 기간의 지연, 비용 증대와 같은 위험관리를 하기 위한 방법으로, SPI 전략이 활발히 진행되고 있다. 사실표준인 CMM이나 국제표준인 SPICE 등이 SPI의 참조적인 모델로 사용된다. 그러나 이들 모델은 특정환경을 가진 소프트웨어 개발 조직에 대한 품질 개선을 위해서 필요한 구체적인 개선 절차와 방법을 기술하고있지 않다. 특히 SPI를 위해서 SPA가 선행되는 경우가 많은데, 효율적인 SPA를 위해서는 심사절차에 대한 정형화가 필요하며 이를 통하여 심사의 일관성을 유지할 수가 있다. 본 논문에서는 심사의 정형화를 위해 SPA의 각 단계들을 UML을 사용하여 표현하고, 모델의 신뢰성을 ISO/IEC 9126의 6가지 품질 특성의 테두리 안에서 검증하고자 한다. 또한 결함들(Defect)간에 연관성을 분석하여, SPA의 등급평가 절차에서 사용되도록 제안한다.

• Journal of Microbiology and Biotechnology
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• 제25권2호
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• pp.206-216
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• 2015

To clarify the role of surface protective antigen A (SpaA) in the pathogenesis of Erysipelothrix rhusiopathiae C43065 (serotype 2), the spaA deletion mutant of E. rhusiopathiae ${\Delta}spaA$ was constructed by homologous recombination. The virulence of the ${\Delta}spaA$ mutant decreased more than 76-fold compared with that of the wild-type strain C43065 in mice. The mutant strain was sensitive to the bactericidal action of swine serum, whereas the wild-type strain was resistant. The adhesion of wild-type strain to MEF cells was inhibited significantly by treatment with rabbit antiserum against recombinant SpaA (rSpaA) as compared with the treatment with normal rabbit serum, but the mutant strain was not affected. The mutant strain was readily taken up by mouse peritoneal macrophages in the normal rabbit serum, whereas the wild-type strain was resistant. Whereas the rabbit antiserum against rSpaA promoted the phagocytosis of wild-type strain by macrophages, the mutant strain was not affected. In addition, mice vaccinated with the formalin-killed mutant strain were provided 40% protection against challenge by the homologous virulent strain as compared with those with wild-type strain, NaOH-extracted antigen, or rSpaA, which provided more than 80% protection against the same infection. These suggested that SpaA has an important role in the pathogenesis of E. rhusiopathiae infection and could be a target for vaccination against swine erysipelas.

• Clinical and Experimental Reproductive Medicine
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• 제43권1호
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• pp.44-50
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• 2016

Objective: This study was performed to assess our clinical experience with single-port access (SPA) laparoscopic cystectomy and myomectomy and the surgical outcomes of those procedures at our institution. Methods: The authors evaluated the surgical outcomes of SPA laparoscopic cystectomy in 293 patients and SPA laparoscopic myomectomy in 246 patients. The surgical outcomes comprised operation time, the amount of blood loss during the operation, the change in hemoglobin (before and after the operation), the change in hematocrit (before and after the operation), switching to the multi-port access method, complications, transfusions, and the duration of the postoperative hospital stay. Results: The Pearson correlation coefficient and the Spearman correlation coefficient between the operation time and the amount of blood loss were 0.312 and 0.321 for SPA laparoscopic cystectomy, respectively, and 0.706 and 0.674 for SPA laparoscopic myomectomy, respectively. The drops in hemoglobin and hematocrit were $1.33{\pm}0.78g/dL$ and $4.14%{\pm}2.45%$, respectively, in SPA laparoscopic cystectomy, while the corresponding figures were $1.34{\pm}1.13g/dL$ and $4.17%{\pm}3.24%$ in SPA laparoscopic myomectomy, respectively. Conclusion: This study reported the surgical outcomes of SPA laparoscopic cystectomy and myomectomy and compared them to previously published findings on traditional laparoscopic cystectomy and myomectomy. No significant differences were found in the surgical outcomes between SPA and traditional laparoscopic cystectomy and myomectomy.

• 한국패션뷰티학회지
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• 제4권1호
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• pp.51-59
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• 2006

Today, SPA fills many of the same needs as they did thousands of years ago, including relaxation, wellness and stress relief by incorporating many of the same methods embraced by the ancients such as a multitude of hydrotherapy treatments, thalassotherapy and massage therapy, one of the most widely used SPA treatments. The definition is as follows: SPA is entities devoted to enhancing overall well-being through a variety of professional services that encourage the renewal of mind, body and spirit. It was from here that the concept of modernday SPA evolved, incorporating full health and beauty services along with sport, aquatic and rest facilities. Todays SPA, a absolute concept, is being specialized and spread as fast as undefinable just in a word. Thalassotherapy, a kind of SPA therapy, contains minerals and trace elements. Born more than 4,000 years ago in ancient Egypt, thalassotherapy comes from the Greek words for thalasso(sea water) and therapeia(to heal). Thalassa was the Greek personification of the Mediterranean Sea that surrounded them and gave them so much of their sustenance. It helps to nourish, hydrate and refine skin texture and also eliminate metabolic waste and toxins in the body. Thalassotherapy is recommended for post-natal and postsurgery recovery period, chronic fatigue, circulatory problems, cellulite control and dermatological problems. It's also possible to enjoy the thalassotherapy SPA as a day guest. Be sure to try the jansu massage, given in the heated sea water pool. As a trained therapist gently whisks clients through the womb-warm water, clients can practically feel the toxins leave their body. Many women from all over the world have been kept up beautiful skin with applying thalassotherapy to their faces and bodies since long times and these days in France, they are getting great curative clinical effects from renovative and scientific technological combination. Thus thalassotherapy will be absolutely ultimate form of natural healing which can keep and recover human's health and beauty.

• International Journal of Oral Biology
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• 제37권2호
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• pp.63-68
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• 2012

It has been documented that SPA0355 exerts antiinflammatory effects via the inhibition of nuclear factor-kappaB activation. In present study, we investigated the inhibitory effects of SPA0355 on periodontitis in an animal model. Periodontitis was induced by ligation of the cervix of the 1st molar in the left mandible in rats. After ligature, the rats were randomly divided into four groups and topically applied with SPA0355 (0.5, 1, and 2%) or the vehicle alone once daily for 10 days. Body weight and food intake were measured daily throughout the experimental period. At day 10 post-ligature, the infiltration of inflammatory cells and distance of the cementoenamel junction (CEJ) to the alveolar bone crest (ABC) in the distal area of ligatured tooth were estimated histopathologically. No changes in body weight or food intake were found between the control and SPA0355 groups. The degree of inflammation was decreased in all three SPA0355 application groups. A decrease CEJ-ABC distance was observed in the 0.5% and 1% SPA0355 groups. These results indicate that SPA0355 inhibits the infiltration of inflammatory cells and alveolar bone resorption and suggests its potential as a therapeutic agent for periodontitis.

• 한국의상디자인학회지
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• 제21권3호
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• pp.121-136
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• 2019

The fashion market is expanding and competition is intensifying due to the contraction of consumption in response to the economic recession and changes in trends. In this study, design characteristics reflecting the brand identity and trend are analyzed as important factors for success. In this study, we will look at the design characteristics of knitwear among SPA brand products and help to plan knit designs. First, six brands were selected based on the sales and the number of stores in domestic and foreign SPA brands. The selected brands include UNIQLO, ZARA, H&M, SPAO, TOPTEN, and 8Seconds. We have selected weft knitting knitwear products(1,736 pieces), which are currently sold in domestic and foreign SPA brands, as silhouette items, knitwear design items, gauges, colors, patterns, images, and items as analysis items to analyze the causes of the differences in the design characteristics of domestic and foreign knitwear. The SPA brand has a wide range of tattoo floors, emphasizing practical aspects, a silhouette that fits the body, and a comfortable daily style. Domestic and foreign SPA brands did not show much difference, but Korean brands had a lower diversity of organization and used color for stable sales, showing a lower concern in trend and strong point color applications. If foreign brands pursue femininity based on a sexy image, Korean brands displayed a difference, emphasizing cute images. As for other design factors, it was found that brand identity was reflected more than domestically. As the cycle of trends becomes shorter, fast fashion is expected to continue in the future, and it is hoped that this research will be used as useful data for design projects of domestic companies.

• 한국의류산업학회지
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• 제17권3호
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• pp.405-420
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• 2015

The purpose of this study is to identify the differences between clothing size satisfaction and clothing sizing systems of Korean and foreign SPA (specialty retailer of private label apparel) brands according to height group, and provide foundation material that can be used to establish product strategy from the perspective of Korean SPA brand clothing sizes in order to secure competitiveness in the international market. Satisfaction of tall women in their twenties with the clothing sizes of SPA brands was researched, and t-test was conducted to examine differences between clothing size satisfaction of Korean and foreign SPA brands between the two height groups. Then, differences in the size minimum and maximum values, size ranges, size intervals and size numbers between clothing sizing systems of Korean and foreign SPA brands were researched and comparatively analyzed. Existing clothing sizes need to make improvements considering the lengths and shoulder width of tall consumers. And Korean SPA brands need to diversify the range and number of sizes in the clothing sizing system, and set a separate tall-size group, or apply the relationship between vertical and horizontal sizes of clothing to establish a clothing sizing system. A product strategy that applies the results of this study will solve the clothing size dissatisfaction of tall female consumers and stimulate sales of Korean SPA brand clothing products. The study has value in that it extracted realistic problems by researching clothing sizing systems of products that are actually sold.

• 한국전자파학회논문지
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• 제23권10호
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• pp.1137-1144
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• 2012

본 논문에서는 펨토셀에서 기기 간의 상호 간섭을 해결하기 위해 2.6 GHz Wimax 밴드용 switched parasitic array(SPA) 안테나를 설계하였다. 설계한 SPA 안테나는 방사체(radiator)로 동작하는 단일 급전 ${\lambda}/4$ 모노폴 안테나가 중앙에 있고, 스위칭에 따라 반사체(reflector)와 유도체(director)로 동작하는 4개의 기생소자가 이를 둘러싸고 있으며, 이들 기생소자는 개방된 모노폴이 각각 둘러싸고 있다. 본 논문에서는 기존의 PIN 다이오드가 아닌 RF FET 스위치를 사용하여 빔 조향을 함으로써 간단한 구조의 저가, 저전력 안테나를 설계하였으며, 스위치의 특성에 따른 SPA 안테나의 성능을 분석하였다. 제작한 안테나의 크기는 반지름 65 mm, 높이 35 mm이고, 2.6 GHz에서 전후방비가 15 dB 이상이며, 스위칭에 따라서 8방향으로 빔 조향이 가능하다.

• Animal Bioscience
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• 제34권2호
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• pp.285-294
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• 2021

Objective: This study was conducted to investigate the supplementary effect of a phytogenic blend (SPA: a mixture containing fermented Schisandra chinensis pomace, fermented Pinus densiflora needle extract, and Allium tuberosum powder in the ratio of 2:2:1) on egg production, egg quality, blood constituents, and visceral organs in laying hens. Methods: A total of 135 Hy-line brown laying hens (48-wk-old) were randomly allocated to three dietary treatments with 5 replicates of 9 hens. The control group (CON) was fed a basal diet (no exogenous SPA addition) and the experimental groups were fed the basal diet containing SPA at the level of 0.1% and 0.3% for 6 weeks. Results: The feed intake was significantly improved in SPA supplemented groups as compared with the control (p<0.05). However, egg production, daily egg mass, and feed conversion ratio were not different among the dietary treatments (p>0.05). For egg quality traits, only Haugh unit (HU) was significantly improved in SPA (0.3%) (p<0.05) as compared with other groups. However, HU was not affected during 4-wk of storage at 18℃ among the dietary treatments (p>0.05). Furthermore, SPA supplementation did not affect the blood biochemical constituents except for the phosphate content, which was significantly higher in SPA groups than the CON group (p<0.05). There were no significant differences in visceral organ characteristics and immune indicators (immunoglobulin A [IgA], IgG, and IgM) in SPA or CON groups. Conclusion: This study suggested that the supplementation of SPA may have beneficial effects on feed intake and egg quality in laying hens.