• Proceedings of the Korean Geotechical Society Conference
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• 2008.10a
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• pp.591-604
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• 2008

In this study, two design examples of drilled shafts on soft ground in Ho-Chi-Minh City, Vietnam are introduced. One is for a 27-story apartment and the other is for a Arch bridge over Saigon river. Unlikely the normal cases in Korea, all of the bored pile foundations are supposed to be placed on soil layers. Therefore, skin friction between pile and ground is the most crucial design parameter. Three methods using SPT N value of sandy soil -Korean Road Bridge Code(1996), Reese and Wright (1977), and O'Neill and Reese (1988)- were adopted to obtain an ultimate axial bearing capacity. In order to verify the calculated bearing capacity, 3 sets of static load test and a Osterberg Cell test were performed at an apartment site and a bridge site respectively. LRFD (Load Resistance Factored Design) method was compared with ASD (Allowable Stress Design) method. On application of ASD method, safety factor for skin friction was adopted as 2 or 3 while safety factor for end bearing was 3. The design bearing capacities from ASD method matched well with those from LRFD method when safety factor for skin friction was adopted as 2.

• Journal of Veterinary Clinics
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• v.40 no.2
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• pp.113-118
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• 2023

Skin and joint diseases are relatively common in dogs. Nutritional complementation is one of the various management strategies for these disorders. This study evaluated the safety and clinical efficacy of Kyungokgo-gamibang in dogs with skin and joint diseases. Thirty dogs with diseases were included and divided into three groups: control group (n = 15), skin group (n = 10), and joint group (n = 5). The skin and joint groups were fed skin and joint gums composed of Kyungokgo-gamibang extract with standard treatment for four weeks. The control group included dogs with skin diseases who were administered standard skin infection treatment for 4 weeks. The physical and laboratory results showed no remarkable adverse effects of Kyungokgo-gamibang extract after its administration in dogs. Clinical efficacy was evaluated using quality of life scale, and levels of cytokines, including interferon-γ, interleukin (IL)-2, IL-6, IL-8, IL-10, monocyte chemoattractant protein-1, and tumor necrosis factor-α, for 4 weeks in all groups. Dermatologic clinical scales were performed for 4 weeks in the control and skin groups. Both the control and skin groups had significantly decreased dermatologic clinical scales, including pruritus and erythema scales (p < 0.05). Among the cytokine levels, only IL-2 concentration was significantly decreased in the skin group after 4 weeks of administration of the Kyungokgo-gamibang extract (p = 0.032). There was no significant difference between the levels of cytokines on days 0 and 28 in the joint group. The quality of life scale was significantly increased after week 4 compared to week 0 in the skin (p = 0.008) and joint groups (p = 0.041). This study suggests that Kyungokgo-gamibang extract can be applied in managing dogs affected by skin and joint diseases without adverse effects.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.05a
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• pp.138-138
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• 2002

• Safety and Health at Work
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• v.7 no.3
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• pp.208-212
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• 2016

Background: Outdoor workers are at risk of high ultraviolet radiation exposure, and may have difficulty using sun protection. The objectives were to determine the prevalence of sun protection behaviors in a sample of outdoor construction workers, and to assess which factors predict better sun protection practices. Methods: Participants were recruited via construction unions. Workers answered a questionnaire on demographics, skin cancer risk, sun protection behaviors, and job. Sun protection behavior scores (from questions on sunscreen use, sleeved shirt, hat, shade seeking, sunglasses) were calculated by converting Likert-scale answers to scores from 0 to 4, and taking the mean (separately for work and leisure). Determinants of sun protection behavior scores were examined for work and leisure using generalized linear models. Results: Seventy-seven workers had complete questionnaire data (participation 98%). Sun protection behaviors used most often were hats (79% often/always) and sleeved shirts (82% often/always); least prevalent were shade-seeking (8% often/always) and sunscreen (29% often/always). For both work and leisure scores, the strongest predictor was skin type, with fairer-skinned individuals having higher sun protection behavior scores. Workers had higher scores at work than on weekends. Workplaces that required hats and sleeved shirts for safety purposes had higher protection behavior scores. Conclusion: This high-participation rate cohort helps characterize sun protection behaviors among outdoor workers. Workers practiced better sun protection at work than on weekends, suggesting that workplace policies supportive of sun protection could be useful for skin cancer prevention in the construction industry.

• Journal of the Korean Institute of Gas
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• v.22 no.6
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• pp.1-7
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• 2018

Currently chemical plant risk have been issued by occurring frequent accidents. Accidents can be generally composed of fire, explosion, release in chemical plant. In case of fire and explosion, accident victims are occurred immediately after accident but release accident, late emergency response cause damage to worker. Especially, there are many victims by late emergency response against chemical exposure to skin. In case of chemical exposure to skin, irreversible damage like death, blindness, burn can be prevented by washing immediately. Safety shower can provide the cleaning for chemical exposure to eye, skin. Most of chemical plants are built in 1980s so equipment become superannuated. In this reason, safety shower also cannot operate normally in emergency situation. Therefor safety shower should be managed by installation and management guideline. This study perform the establishment guideline for safety shower installation and inspection to increase the reliability.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.8
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• pp.1213-1219
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• 2010

We evaluated the anti-aging potential and safety of black garlic extract for cosmeceutical ingredient. Black garlic was made by spontaneous fermentation for 40 days at $60{\sim}70^{\circ}C$, 85~95% RH without any additives. The 10% black garlic extract had sweet odor, antioxidant activities and inhibitory activities of skin againg enzymes such as tyrosinase and elastase. The skin safety was performed to evaluate of potential toxicity using the primary irritation test and skin sensitization test. The black garlic extract did not show any adverse reactions such as erythema and edema on intact skin sites at primary irritation test, but on abraded sites, some experimental animals showed very slight erythema. So, the black garlic extract was classified as a practically non-irritating material based on the score 0.23 of primary irritation index. The skin sensitization study was tested by the guinea pig maximization test (GPMT) and Freund's complete adjuvant (FCA) with intradermal injection of 10% black garlic extract. The skin sensitization test showed no skin sensitization. The allergic sensitization depends on tumor necrosis factor-$\alpha$ (TNF-$\alpha$) and interleukin-6 (IL-6). The concentration of IL-6 on challenged tissue of treated with black garlic extract was not significantly different with negative control group (saline treated group). Based on this study, the potential for black garlic as a cosmeceutical ingredient was proven.

• Safety and Health at Work
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• v.6 no.3
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• pp.256-262
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• 2015

Background: Heart attack is the most common cause of line-of-duty death in the fire service. Daily aspirin therapy is a preventative measure used to reduce the morbidity of heart attacks but may decrease the ability to dissipate heat by reducing skin blood flow. Methods: In this double-blind, placebo-controlled, crossover study, firefighters were randomized to receive 14 days of therapy (81-mg aspirin or placebo) before performing treadmill exercise in thermal-protective clothing in a hot room [$38.8{\pm}2.1^{\circ}C$, $24.9{\pm}9.1%$ relative humidity (RH)]. Three weeks without therapy was provided before crossing to the other arm. Firefighters completed a baseline skin blood-flow assessment via laser Doppler flowmetry; skin was heated to $44^{\circ}C$ to achieve maximal cutaneous vasodilation. Skin blood flow was measured before and after exercise in a hot room, and at 0 minutes, 10 minutes, 20 minutes, and 30 minutes of recovery under temperature conditions ($25.3{\pm}1.2^{\circ}C$, $40.3{\pm}13.7%\;RH$). Platelet clotting time was assessed before drug administration, and before and after exercise. Results: Fifteen firefighters completed the study. Aspirin increased clotting time before and after exercise compared with placebo (p = 0.003). There were no differences in absolute skin blood flow between groups (p = 0.35). Following exercise, cutaneous vascular conductance (CVC) was $85{\pm}42%$ of maximum in the aspirin and $76{\pm}37%$ in the placebo groups. The percentage of maximal CVC did not differ by treatment before or after recovery. Neither maximal core body temperature nor heart rate responses to exercise differed between trials. Conclusion: There were no differences in skin blood flow during uncompensable heat stress following exercise after aspirin or placebo therapy.

• International Journal of Aerospace System Engineering
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• v.6 no.1
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• pp.1-7
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• 2019

In the present study, structural safety and stability on the main wing and tail planes of the 1.2 ton WIG(Wing in Ground Effect) flight vehicle, which will be a high speed maritime transportation system for the next generation, was performed. The carbon-epoxy composite material was used in design of wing structure. The skin-spar with skin-stressed structural type was adopted for improvement of lightness and structural stability. As a design procedure for this study, the design load was estimated with maximum flight load. From static strength analysis results using finite element method of the commercial codes. From the stress analysis results of the main wing, it was confirmed that the upper skin structure between the second rib and the third rib was unstable for the buckling load. Therefore in order to solve this problem, three stiffeners at the buckled region were added. After design modification, even though the weight of the wing was a little bit heavier than the target weight, the structural safety and stability was satisfied for design requirements.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.478-481
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• 2013

This study was performed to evaluate the acute skin and eye irritation of plant extracts (neem and sophora) against rabbit. The result of skin irritation test indicated that neem extracts and sophora extracts were not irritant. For eye irritation test, the result showed no irritation for neem extracts. Sophora extracts have a severe eye irritation and the symptoms have been reduced to day 3. Thus, safety guidelines for agricultural workers is considered to be needed when sophora extracts is used as an organic agricultural materials.

• 한국신재생에너지학회:학술대회논문집
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• 2009.11a
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• pp.422-422
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• 2009

This paper describes the structural design of small wind turbine blade by using design of experiments. Blade structure consists of skin, spar and foam. The materials for skin and spar are a kind of Glass/Epoxy and form is polyurethane. It has 7 lay-ups with different ply angle. A factorial design is applied to design the ply angles considering manufacturing constraints and to investigate the safety factor which is calculated by structural analysis. In order to perform the structural analysis, the commercial software ABAQUS is used. Tsai-Wu failure criterion is chosen to compute safety factor. The determination of the significance of effects in the experiments is made through the analysis of variance. The results show that ply angle at skin affects the safety factor of wind turbine blade. And from this result, optimal ply angles of composite blade are achieved.