• Journal of Astronomy and Space Sciences
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• 제14권1호
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• pp.126-135
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• 1997

전파연구소 이천분소에서는 1996년 8월에 지자기연속관측시스템을 이천분소(이천관측소: N37.1447, E127,5509)와 경희대학교(용인관측소: N37.1419, E127.0454)에 각각 설치하여 현재 관측중에 있으며, 현재 이것의 데이터베이스를 구축하고 있다. 또한 1997년 여름쯤에는 제주도(제주대학교)에 관측시스템 1식을 추가로 설치하여 한반도의 위도별 지자기 변화를 실시간으로 모니터할 예정이다. 본 논문에서는 이천 및 용인관측소에서 1996년 12월 2일에 관측한 CME(Coronal Mass Ejection)을 Kakioka 관측소, WIND 및 Geotail 위성에서 관측 한 데이터들을 비교 분석하였다.

• 한국실내디자인학회논문집
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• 제20권4호
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• pp.183-190
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• 2011

Lately majority of churches have preferred to enlarge their worship area to both horizontal and vertical axis. According to expand their area which brings more devotees to the limited service area. Transform from a small church into a large church is no longer unprecedented issue in South Korea. As the size of church getting bigger, many unexpected issues become matters. One of the significant problem is that the number of people have experienced either fall a sleep or feel a doziness during their service period. Due to the limited condition for the specific building type such as religion facility(church), IAQ improvements is seriously concerned. Therefore, we are going to examine by using simulation tool, CF, a difference of ventilation efficiency about the location and number of windows, and find the best way of the ventilation efficiency in a multi-stories type church by changing the exhaust pipes location and size. Furthermore, in this thesis, by changing a ceiling height from the existing building to confirm that $CO_2$ have been satisfied for both the ventilation efficiency and IAQ.

• Animal cells and systems
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• 제15권1호
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• pp.37-43
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• 2011

The Korean freshwater crayfish, Cambaroides similis, has recently suffered from range reduction and habitat degradation caused by environmental changes and water pollution. For the conservation and restoration of this species, it is necessary to understand the current population structures of Korean C. similis using estimation of their genetic variation. In this study, eight micro satellite loci were developed and characterized from 49 individuals collected from four locations: one population from Mt. Bukhan (BH) and three populations from Mt. Gwanak (GA) in Seoul, Korea. As a result, the number of alleles per locus ranged from 2 to 12. The observed heterozygosities and expected heterozygosities ranged from 0.000 to 0.833 and from 0.125 to 0.943, respectively, and the former values were significantly lower than the latter ones expected under the Hardy-Weinberg equilibrium. No significant linkage disequilibrium was revealed between any of the locus pairs after Bonferroni correction. From the pairwise Fst results over all samples, higher differentiation between GA-BH population pairs (mean 0.1789) was observed than between GA population pairs (mean 0.0454). This was also supported by Mantel's test showing that the genetic distances of these crayfish populations were significantly correlated with geographic distances. This result may show the regional differentiation caused by restricted gene flow between northern (BH) and southern (GA) populations within Seoul. These micro satellite markers have the potential for use in analyses of the genetic diversity and population structure of C. similis species, with implications for its conservation and management plans.

• 한국임상약학회지
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• 제20권3호
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• pp.255-261
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• 2010

Cefprozil is a broad-spectrum oral beta-lactam cephalosporin consisting of cis- and trans-isomeric mixture whose ratio is approximately 90:10. Cefprozil is used to treat certain infections caused by bacteria such as bronchitis and ear, skin, and throat infections. The purpose of the present study was to evaluate the bioequivalence of two cefprozil tablets, $Cefzil^{(R)}$ tablet 250 mg (BMS Pharmaceutical Korea., Ltd.) and Procezil tablet 250 mg (Hanmi Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The in vitro release of cefprozil from the two cefprozil formulations were tested using KP VIII Apparatus I method with water dissolution media. Thirty five healthy male subjects, $24.00{\pm}1.53$ years in age and $69.77{\pm}9.99$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After four tablets containing 1000 mg as cefprozil were orally administered, blood samples were taken at predetermined time intervals and the concentrations of cefprozil in serum were determined using HPLC/UV detector. The dissolution profiles of two formulations were similar in water tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ on the basis of total-cefprozil were calculated, and computer program (K-BE Test 2002) was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Cefzil^{(R)}$ tablets, were -0.81%, -3.00% and -6.83% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.9515~log 1.0454 and log 0.9613~log 1.0465 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Procezil tablet was bioequivalent to $Cefzil^{(R)}$ tablet.