• Bulletin of the Korean Chemical Society
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• v.32 no.7
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• pp.2397-2404
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• 2011

Variable selection k nearest neighbor QSAR modeling approach was applied to a data set of 80 3-arylisoquinolines exhibiting cytotoxicity against human lung tumor cell line (A-549). All compounds were characterized with molecular topology descriptors calculated with the MolconnZ program. Seven compounds were randomly selected from the original dataset and used as an external validation set. The remaining subset of 73 compounds was divided into multiple training (56 to 61 compounds) and test (17 to 12 compounds) sets using a chemical diversity sampling method developed in this group. Highly predictive models characterized by the leave-one out cross-validated $R^2$ ($q^2$) values greater than 0.8 for the training sets and $R^2$ values greater than 0.7 for the test sets have been obtained. The robustness of models was confirmed by the Y-randomization test: all models built using training sets with randomly shuffled activities were characterized by low $q^2{\leq}0.26$ and $R^2{\leq}0.22$ for training and test sets, respectively. Twelve best models (with the highest values of both $q^2$ and $R^2$) predicted the activities of the external validation set of seven compounds with $R^2$ ranging from 0.71 to 0.93.

• Journal of the Korean Home Economics Association
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• v.42 no.10 s.200
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• pp.63-77
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• 2004

The overuse of Internet has caused the problem of 'Internet addiction' in the life of college students. The purpose of this study was to develop a program of time management education for preventing Internet addiction among college students. The program consists of sessions. The first session is an introduction to the program which includes a pre-test about Internet addiction. The second session is designed to allow them to check their pattern of Internet use and time use by themselves. The third session is designed to set their tie goals and make long-range plans. The fourth session is designed to make short-range plans and look for alternative activities. The final session is the completion of the program. This study has some significance in developing a time management program for Internet addiction. and will be utilized in practical education.

• The Journal of Korean Physical Therapy
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• v.30 no.4
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• pp.112-116
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• 2018

Purpose: This study aimed to identify the effects of a task-oriented exercise program on balance in patients with acute stroke. Methods: Twenty participants with hemiparesis resulting from acute stroke volunteered to participate in this study. They were randomly assigned to either the experimental or control group, with 10 patients per group. Both groups underwent a task-oriented exercise program averaging 30 minutes daily for 4 weeks. Balance was assessed before and after the 4-week training period. Before and after the intervention, we conducted a paired t-test to compare the within-group changes and an independent t-test to compare the between-group differences. The statistical significance level was set at p=0.05 for all the variables. Results: Both groups showed significant within-group and between-group changes in balance (p<0.05) after the intervention. Conclusion: This study provides valuable information for future studies in this field. Further research using a larger sample and longer experiment spans can corroborate the results of our study.

• The KIPS Transactions:PartD
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• v.8D no.1
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• pp.81-86
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• 2001

one key goal of software testing is to generate a 'good' test data set, which is consideres as the most difficult and time-consuming task. This paper discusses how genetic algorithns can be used for automatic generation of test data set for software testing. We employ mutation testing to show the effectiveness of genetic algorithms (GAs) in automatic test data generation. The approach presented in this paper is different from other in that test generation process requireas no lnowledge of implementation details of a program under test. In addition, we have conducted some experiments and compared our approach with random testing which is also regarded as a black-box test generation technique to show its effectiveness.

• Korean Journal of Health Education and Promotion
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• v.16 no.2
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• pp.205-233
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• 1999

This study is an effort to make policy suggestions by analysing the current health examination program as a benefit service provided by the national health insurance system, including health screening for the insured, screening of cancer and chronic diseases for their dependents. Analyses found some issues being gave attention to; 1) The insured under the community health insurance system do not get the health examination benefit. A program for them should be set to have equity in benefit services. 2) Low rates of using screen services compromise purpose and the efficiency the services have first intended to. An immediate attention should be made to increase low rate of use of screen test to detect chronic diseases in particular. 3) Selection of diseases and test items covered by health examination program does not reflect the need of the insured, but to reflect financial resources of the national health insurance system. 4) Lack of health screening facilities and their geographical maldistribution is observed, which with preference of a general hospital as a screening post by the insured may lead to unreliable test. 5) A follow-up system should have been developed for the suspected classified by test results of carrying chronic diseases. They should be cared for within the health examination program. Public health care systems incorporate such a system, along with caring for those who are in need of having a health counselling on preventive care. In conclusion, the national health insurance system should be a medical insurance of giving a higher priority on preventive care benefits, health examination program in particular. That could be done by making rearrangements of test items, screening methods and system, rationalizing current reimbursement system of service fee, increasing accessibility to and utilization of the services, and making an establishment of follow-up system.

• Journal of The Korean Society of Integrative Medicine
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• v.2 no.3
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• pp.1-7
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• 2014

Purpose : The purpose of this study was to evaluate the influence of Lowenstein Occupational Therapy Cognitive Assessment(LOTCA) and Activities of Daily Living(ADL) by CogPack program in elderly with Alzheimer's dementia. Method : The subjects of this study, elderly diagnosed with Alzheimer's dementia, 8 patients were picked up, who were agreed with this research. Cognitive training for 6 weeks, which consisted of 3 times per week, 30 min of memory, attention and performance with cogpack program. Cognitive and ADL measured by LOTCA and FIM. The SPSS Ver. 14.0 statistical program was used for data processing. The significance level for statistical inspection was set as 0.05. Result : In comparison of LOTCA was significantly correlated in the pre and post test but FIM was not significantly correlated in the pre and post test. Conclusion : Therefore, the CogPack program is useful to improve the LOTCA in elderly with Alzheimer's dementia.

• Physical Therapy Korea
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• v.19 no.4
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• pp.32-37
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• 2012

The purpose of this study was to investigate the quantitative data of downward pulling tension in subjects with scapular downward rotation syndrome (SDRS) before and after 6-week self scapular upward rotation exercise (SURE) program. Eleven subjects with bilateral SDRS. The downward pulling tension(DPT) was measured digital tension-meter. The tension force data were collected using a surface electromyography before and after a 6-week self-scapular SURE program. The significance of difference between pre- and post-program was assessed using a paired t-test, with the level of significance set at ${\alpha}$=.05. The results showed that significant differences between pre- and post-SURE program were found for DPT (p<.05). These findings suggest that 6-week self SURE program is effective for reducing DPT in subjects with SDRS. Additionally, our DPT measurement can be useful for maintaining shoulder position and providing quantitative data between pre- and post-SURE program during passive correction of scapular position test.

• Journal of The Korean Society of Integrative Medicine
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• v.2 no.2
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• pp.13-20
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• 2014

Purpose : The purpose of this study was to evaluate the influence of cognition and executive function by computer - based attention program in vascular dementia. Method : The subjects of this study, old man diagnosed with vascular dementia, 12 patients were picked up, who were agreed with this research and were having hospital care for 4 weeks at nursing care centers. Computer-based attention program was applied to vascular dementia. Cognitive function measured by a K-MMSE and executive function measured by ACL. The SPSS Ver. 18.0 statistical program was used for data processing. The significance level for statistical inspection was set as 0.05. Result : In comparison of cognitive function was not significantly correlated in the pre and post test and executive function was significantly correlated in the pre and post test. Conclusion : Therefore, the computer-based attention program is useful to improve the cognitive and executive function in elderly with vascular dementia.

• Journal of The Korean Association For Science Education
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• v.6 no.2
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• pp.1-7
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• 1986

The summary of the distinguishing features of the program(developed In this research) 1. For the high school physics 1, total of 67 kinds of physical concepts. 31 of physical low. 84 of equations. 23 of units, and 191 of new sample problems were imputed (in the data file) 2. Physical concepts, lows, equations, and units could be studied by chapter 3. Among 191 of sample problems, the user can choose his own set of problems according to chapters and difficulties. 4. The content, a set of problems chosen, and a result for test will be printed for a hard copy. 5. An extra effect was done to use same character for physical quantities as in a text book.

• Journal of Digital Convergence
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• v.12 no.3
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• pp.317-323
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• 2014

This research has a purpose of providing base data to prevent musculoskeletal disorders, by analyzing the changes in muscle body due to sling exercises, of the industrial laborers with work-related musculoskeletal disorders. The subjects of this research are 20 volunteers who applied for musculoskeletal treatment exercises in hospitals, from region D industry H. 10 of the 20 subjects were involved in sling exercise program for 12 weeks, and the other 10 subjects were ordered to retain their common practices. We have used the statistics software SPSS ver.18.0 to analyze the data, and have offered a descriptive analysis of the measured variables. To discover the sling exercise effects, we have executed a t-test (paired sample t-test) comparing the before-after relationship of 12-week sling exercise program, and the level of significance were set to a=.05. With these set of research methods and procedures, we have concluded the following. As a result, we have concluded that 12-week sling exercise program does exert influence in changing muscle body of work-related musculoskeletal patients.