• Title/Summary/Keyword: Test&Evaluation

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Development of Dissolution Test for Itopride Hydrochloride Tablets and Tiropramide Hydrochloride Tablets (이토프리드염산염 정과 티로프라미드염산염 정의 용출시험법 개발)

  • Kim, Jung Hyun;Lee, Jong Hwa;Choi, Lan;Choi, Yeon Hee;Lee, Jong Chul;An, Ji Hye;Lee, Gwang Moon;Shim, Young Hoon;Kang, Shin-Jung;Sah, Hong-Kee;Choi, Hoo-Kyun;Kim, In-Kyu
    • YAKHAK HOEJI
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    • v.57 no.3
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    • pp.205-212
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    • 2013
  • Dissolution test has been performed to control drug quality and to predict in vivo drug release profile of solid dosage forms, so there's a drift towards setting dissolution test instead of disintegration test. However, some solid dosage forms in Korea Pharmaceutical Codex (KPC) are not established the dissolution test yet, so these monographs are necessary to set the specification of dissolution test. In this study, we developed the specification and test method of dissolution test for itopride hydrochloride tablets and tiropramide hydrochloride tablets which are not established the dissolution test yet. According to the "Manual for Guideline Application for Validation of Analytical Procedures" and "Guidelines on Specification of Dissolution test for Oral dosage form" of Korean Pharmacopoeia (KP), we validated and established each development method. Based on the preliminary dissolution profile, we set the dissolution condition(paddle apparatus, pH 1.2 media, 50 rpm). For this condition, we performed the main dissolution test to determine the specification (45 min, 85%). Finally, we validated each analytical method by specificity, linearity, accuracy and precision. These developed methods will be included the next supplement of KPC and also contributed to the quality control of medicines.

A Study on Evaluation of Liquefaction Potential Using in Situ Test Data (원위치 시험 성과에 의한 액상화 발생가능성 평가에 관한 연구)

  • 허정우;김찬홍;박성재;정경환
    • Proceedings of the Korean Geotechical Society Conference
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    • 2001.03a
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    • pp.477-484
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    • 2001
  • In this paper shows the evaluation of the liquefaction potential of soils using in situ test. There are different types of in situ test used in the evaluation the liquefaction potential. In the particular study the Standard penetration test(SPT), Cone penetration test(CPT), ad Seismic cone penetration test (SCPT) were used. The SPT N value has been used all over for a very long time. The evaluation of the liquefaction of soil was preformed using the worldwide renowned CPT and SCPT. Shake 91 program was used to evaluate the results obtained by different in situ test and were later analyzed.

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Evaluation of Ramp Test Using Human Perception (인지적 평가기준을 이용한 Ramp Test의 특성평가)

  • Kim, Jung-Soo
    • Journal of the Korean Society of Safety
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    • v.27 no.3
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    • pp.9-14
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    • 2012
  • The objectives of this study were to compare the results of HSL (Health and Safety Laboratory) ramp test with perceived sense of slip onto the several different floor surfaces under contaminated conditions. There are a variety of approaches from biomechanical measurements to psychophysical test and human perception. However, controversies over these approaches still remain. Some widely accepted methods need to be improved. AHP (Analytic Hierarchy Process) was used to evaluate the perception of slipperiness of seven different floor surfaces under the contaminated condition with glycerol solution. Twelve subjects worn same footwear and walked with self-selected step and cadence along the test floors. The angle of inclination obtained for water wet condition using 5 l/min with HSL ramp test was compared to perception of slipperiness. The surface roughness ($R_z$) related very well both AHP (r=0.95) and ramp test (r=0.92). The high significant correlation (r=0.90) was found between AHP and HSL ramp test.The HSL ramp test values (Coefficient of Friction, COF) according to subjective evaluation were divided into two categories. There were high correlations between test results (subjective evaluation, HSL ramp test) and surface roughness in Rz. Perception rating obtained with AHP showed a high correlation with COF obtained with HSL ramp test.

Load Test and Remote Monitoring of P.C. Box Girder Bridge (P.C. BOX 교량의 재하시험 및 원격계측 유지관리 시스템)

  • Lee, Sung-Woo;Doobyong Bae;Lee, Sun-Goo
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1995.10a
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    • pp.122-131
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    • 1995
  • Load test for newly introduced precast segmental bridge is carried out to experimentally evaluate load carrying capacity, Analysis accompanied with the test is also performed and the results are used in the evaluation. In addition to initial evaluation of the bridge by load test, remote dynamic monitoring system to perform realtime assessment of the bridge condition is also under development. In this paper the procedure and results of load test and evaluation are presented along with introduction of dynamic monitoring system.

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Construction of Evaluation Process and Test System for Embedded Software (임베디드 소프트웨어의 평가 프로세스와 시험체계의 구축)

  • Yang, Hae-Sool;Shin, Seok-Kyoo;Jung, Hye-Jung
    • The KIPS Transactions:PartD
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    • v.11D no.3
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    • pp.659-670
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    • 2004
  • It is possible to implement high quality system which coincided with embedded system purchaser's requirements by quality test. The concrete quality test system applicable within our country for embedded software was not constructed yet. Recently, various embedded systems are developed, but they have many problems such as recall by defect. In this paper, we developed evaluation modules and quality test fables which can implement duality test based on ISO/IEC 12119 for embedded software evaluation.

Study on Application Method of QFD in the Test Evaluation Phase in Connection with Se Process (SE 프로세스와 연계한 시험평가 단계의 QFD 적용방안 연구)

  • Park, Jong Wan;Lee, Jae Woo
    • Journal of the Korean Society of Systems Engineering
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    • v.14 no.2
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    • pp.1-7
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    • 2018
  • The research and development stage can improve the goal level of the project through systematic operation and management of systems engineering. The test evaluation tasks in the R&D process have a lot of connections with the system engineering in terms of requirement management, and the methodology for deriving the requirements when establishing the test evaluation items has been consistently required. In this paper, we propose the process of effectively establishing and using QFD (Quality Function Deployment), a tool to manage customer requirement, and drawing up HOQ (House of Quality) in the search and exploratory development stage of the self - propelled mortar project.

Safety Evaluation through Field Load Test of RC Slab Bridge (RC 슬래브 교량의 현장재하시험을 통한 안전성 평가)

  • Cho, Han-Min
    • Journal of Urban Science
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    • v.11 no.1
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    • pp.9-13
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    • 2022
  • Currently, RC slab bridges in use in Korea account for most of the total bridges, and bridges with a service life of 20 years or more account for about 75%. However, most of these RC slab bridges have a span of less than 20m and are not included in the first and second types of facilities, so maintenance is very neglected. Therefore, in this study, field load test is performed on an aged RC slab bridge, and the performance evaluation is performed based on the structural response results (deflection, impact coefficient, natural frequency, etc.) of the bridge obtained through field load test. In addition, the performance evaluation results obtained through the load test are intended to be used as basic data for the damage evaluation process of the bridge currently under development.

A study of the Development of Ship Integrated Combat Capability Operational Test and Evaluation using Missile Live-Fire and Reaction Time Analysis (유도탄 실사격 및 반응시간 분석보고서를 활용한 함정 통합전투성능 운용시험평가 발전방안 제시)

  • Kim, Byungjun;Kang, Jeongseok;Hur, Jangwan;Ko, Jangsoo
    • Journal of the Korea Institute of Military Science and Technology
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    • v.25 no.3
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    • pp.259-266
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    • 2022
  • This study aims to introduce missile live-fire during the ship operational test and evaluation(T&E) as a means of verifying the integrated combat capability(ICC) of various systems installed on naval ships. The research method identified domestic and foreign T&E systems and cases, and reports related to ICC, which were written during the ship's design stage. As a result of research, Republic of Korea is not conducting the missile live-fire at the ship T&E stage due to the lack of relevant systems, while the U.S. is conducting it based on the mission-based T&E and the end-to-end test system. As a way to improve within the current domestic ship acquisition systems, the reaction time analysis, a quantitative analysis result of ICC calculated at the ship basic design stage, was proposed to be verified by missile live-fire during ship operational T&E.

Performance evaluation facilities and evaluation methods for hydropower equipment (해외 수력발전설비 성능평가설비 및 평가 방법)

  • Kim, Youngjoon;Kim, Yongyeol;Cho, Yong;Ko, Jaemyoung
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.194-194
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    • 2010
  • The variable demand on the energy market, as well as the limited energy storage capabilities, requires a great flexibility in operating hydraulic turbines. But, present in Korea, the absence of testing laboratories and technical criteria for the performance test of small hydropower degrades the efficiency of the domestic hydropower machines, A performance guarantees for hydro turbines shall be contain, as a minimum, guarantees covering power, discharge and specific hydraulic energy, efficiency, maximum momentary overspeed and maximum momentary pressure and/or maximum steady-state runaway speed, as well as guarantees related to cavitation. Performance test are conducted by the test standard. Test codes based on extensive research data are written under the leadership of an IEC. Performance evaluation is carry out several test(performance test, cavitation test and runaway test). The paper presents the international turbine test laboratory and performance test standard.

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Rutting Potential Evaluation of Asphalt Mixtures by Repeated-Load Creep Test (반복하중 크리프시험에 의한 아스팔트 혼합물의 소성변형특성 평가)

  • Zhu L.Y.;Fwa T.F.
    • International Journal of Highway Engineering
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    • v.8 no.3 s.29
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    • pp.21-28
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    • 2006
  • Field or laboratory wheel tracking tests have been employed for the evaluation of the rutting potential of asphalt paving mixtures. Compared to field tests, laboratory wheel tracking tests are much less expensive and more manageable for most road projects. However, most test laboratories are not equipped to perform such tests because there does not exist any standard test procedure, and the required equipment is rather expensive. Futhermore, the size of test specimens and the relatively large quantity of test mixture required present difficulties for laboratory specimen mixing and compaction. This paper describes a project conducted to study the feasibility of replacing wheel tracking testsby a repeated-load creep test for rutting potential evaluation. Comparisons were made between the results of the two tests for different test temperatures, loading speeds and applied pressures. Three types of asphalt mixtures were studied in the test program. Favorable conclusions concerning the use of the repeated-load test for rutting potential evaluation were drawn based on the findings of the experimental test results. The correlation between the two types of tests was found to be good for all threeasphalt mixtures. Adopting the repeated-load creep test would lead to cost savings since it employs standard test equipment already available in most laboratories. It would also result in substantial time savings due to the much smaller quantity of mix needed, and the ease in specimen preparation.

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