• Journal of Ginseng Research
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• 제39권4호
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• pp.392-397
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• 2015

Background: Red ginseng (RG) is processed from Panax ginseng via several methods including heat treatment, mild acid hydrolysis, and microbial conversion to transform the major ginsenosides into minor ginsenosides, which have greater pharmaceutical activities. During the fermentation process using microbial strains in a machine for making red ginseng, a change of composition occurs after heating. Therefore, we confirmed that fermentation had occurred using only microbial strains and evaluated the changes in the ginsenosides and their chemical composition. Methods: To confirm the fermentation by microbial strains, the fermented red ginseng was made with microbial strains (w-FRG) or without microbial strains (n-FRG), and the fermentation process was performed to tertiary fermentation. The changes in the ginsenoside composition of the self-manufactured FRG using the machine were evaluated using HPLC, and the 20 ginsenosides were analyzed. Additionally, we investigated changes of the reducing sugar and polyphenol contents during fermentation process. Results: In the fermentation process, ginsenosides Re, Rg1, and Rb1 decreased but ginsenosides Rh1, F2, Rg3, and Compound Y (C.Y) increased in primary FRG more than in the raw ginseng and RG. The content of phenolic compounds was high in FRG and the highest in the tertiary w-FRG. Moreover, the reducing sugar content was approximately three times higher in the tertiary w-FRG than in the other n-FRG. Conclusion: As the results indicate, we confirmed the changes in the ginsenoside content and the role of microbial strains in the fermentation process.

• 임상간호연구
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• 제14권1호
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• pp.161-172
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• 2008

Purpose: This study was to classify patient severity score for hemodialysis patients. Method: The subject of this study was 1,575 patients. To study the severity of the patients, we used t-test and ANOVA. The congruity was measured by Kappa coefficient and the severity in each medical facility was analyzed by ANOVA. Result: The results showed that there was a significant difference according to the levels of medical center (F=171.187, p<.0001). Categorizing the severity of the patients in each medical facility, group II and III of the secondary medical institution had higher ratio than the primary medical institution. There was not a single patient coming under group IV in both of the primary or secondary medical institutions. However, the tertiary medical institutions had more subjects in group II and III than the primary and secondary medical institutions. The group IV with the highest severity had 11 patients(1.5%), demonstrating that the tertiary medical institution had higher severity patients than the primary or secondary medical institutions. Conclusion: The results of this study appropriately reflects the repayment system of medical expenses by the government. Also, it provides the fundamental information to develop nursing fee system taken into account of the systemic differences among the primary, secondary and tertiary medical institutions.

• 디지털융복합연구
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• 제16권7호
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• pp.213-222
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• 2018

본 연구의 목적은 고등 수학교육에 있어서 스마트 러닝의 특징적 적용을 통해 교육환경의 확장과 학습자 역량의 확장을 시도하고 그 효과성을 분석하는 것이다. 본 연구는 2017년 G대학에서 1학년 학생들의 공학인증 과목 중 하나인 미적분학I을 수강하는 화공생명학과 학생들 118명을 실험집단과 비교집단으로 분리하여 스마트러닝의 효과성을 검증하였다. 즉 수업에서 공학도구를 활용한 다양한 학습활동과 SNS를 통한 교수자와 학습자 간의 활발한 상호작용이 시각적 이해와 수학적 개념형성, 그리고 학습성과에 미치는 영향을 분석하였다. 연구결과에 따르면 실험집단에서 긍정적인 학업성취를 보였으며 학습자들의 만족도가 높았다. 본 연구는 고등 수학교육에서 스마트러닝의 가능성을 확인하였으며 향후 질 높은 스마트러닝을 실현하기 위한 전략을 제안한다.

• 자원환경지질
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• 제29권6호
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• pp.753-765
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• 1996

It is a well known fact that the remanent magnetization direction of the Tertiary rocks is deflected significantly clockwise (about $50^{\circ}$) in the Tertiary basins of the southeastern part of Korean peninsula. This fact has been interpreted as an evidence of north-south spreading of the East Sea (Sea of Japan) and dextral strike-slip motion of the Yangsan fault. As deflection (rotation) of remanent magnetizations is frequently reported from various regions of the world in the vicinities of strike-slip fault, such phenomena are to be expected in the Yangsan fault region also. It was the purpose of this study to clarify whether such premise is right or not. A total of 445 independently oriented core samples were collected from Cretaceous rocks of various lithology (sedimentary rocks, andesites and I-type granites) in the Yangsan fault area. In spite of through AF and thermal demagnetization experiments, no sign of remanent magnetization deflection was found. Instead, palaeomagnetic poles calculated from formation-mean ChRM directions are very similar to those of contemporary (Barremian, and late Cretaceous-Tertiary) sedimentary and plutonic rocks in the other parts of $Ky{\check{o}}ngsang$ basin as well as those of China. Therefore, possibility of tilting of granite plutons and horizontal block rotation of study area is excluded. It is also concluded that the Yangsan fault did not take any significant role in the Cenozoic tectonic evolution of southeast Korea and the East Sea region. The boundary between rotated and unrotated region of remanent magnetization is not the Yangsan fault line, but must lie further east of it.

• Nutrition Research and Practice
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• 제12권3호
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• pp.215-221
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• 2018

BACKGROUND/OBJECTIVES: The prevalence of malnutrition among hospitalized children ranges between 12% and 24%. Although the consequences of hospital malnutrition are enormous, it is often unrecognized and untreated. The aim of this study was to identify the current status of in-hospital nutrition support for children in South Korea by carrying out a nationwide hospital-based survey. SUBJECTS/METHODS: Out of 345 general and tertiary hospitals in South Korea, a total of 53 institutes with pediatric gastroenterologists and more than 10 pediatric inpatients were selected. A questionnaire was developed by the nutrition committee of the Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition. The questionnaires were sent to pediatric gastroenterologists in each hospital. Survey was performed by e-mails. RESULTS: Forty hospitals (75.5%) responded to the survey; 23 of them were tertiary hospitals, and 17 of them were general hospitals. Only 21 hospitals (52.5%) had all the required nutritional support personnel (including pediatrician, nutritionist, pharmacist, and nurse) assigned to pediatric patients. Routine nutritional screening was performed in 22 (55.0%) hospitals on admission, which was lower than that in adult patients (65.8%). Nutritional screening tools varied among hospitals; 33 of 40 (82.5%) hospitals used their own screening tools. The most frequently used nutritional assessment parameters were weight, height, hemoglobin, and serum albumin levels. In our nationwide hospital-based survey, the most frequently reported main barriers of nutritional support in hospitals were lack of manpower and excessive workload, followed by insufficient knowledge and experience. CONCLUSIONS: Although this nationwide hospital-based survey targeted general and tertiary hospitals with pediatric gastroenterologists, manpower and medical resources for nutritional support were still insufficient for hospitalized children, and nutritional screening was not routinely performed in many hospitals. More attention to hospital malnutrition and additional national policies for nutritional support in hospitals are required to ensure appropriate nutritional management of hospitalized pediatric patients.

• 한국산학기술학회논문지
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• 제14권9호
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• pp.4635-4642
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• 2013

화력발전소로부터 배출되는 이산화탄소를 분리하기 위하여 급수가 다른 아민을 혼합한 개선 흡수제를 개발하고자 하였다. 급수가 다른 1, 2, 3급 아민을 혼합한 후 이산화탄소 부분압에 따른 이산화탄소 흡수능을 조사하였다. 동일한 압력에서 이산화탄소 흡수능은 3DMA1P 30wt%>3DMA1P 27wt%+MEA 3wt%>3DMA1P 27wt%+DEA 3wt% 순으로 나타내었으며, 이는 3급인 3DMA1P에 2급인 DEA보다는 1급인 MEA를 혼합하는 것이 우수한 흡수능을 보이고 있다. 따라서 흡수능이 우수한 3급 아민에 흡수속도를 높이기 위하여 1급 아민을 혼합하는 것이 유리함을 알 수 있다. 최종적으로 준경험 기액 평형모델을 이용하여 실험 결과를 계산한 결과 실험치와 잘 일치하였다.

• Bulletin of the Korean Chemical Society
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• 제15권10호
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• pp.881-888
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• 1994

The approximate rates and stoichiometry of the reaction of excess sodium tris(diethylamino)aluminum hydride (ST-DEA) with selected organic compounds containing representative functional groups under standardized conditions(tetrahydrofuran, $0{\circ}$) were studied in order to characterize the reducing characteristics of the reagent for selective reductions. The reducing ability of STDEA was also compared with those of the parent sodium aluminum hydride (SAH) and lithium tris(diethylamino)aluminum hydride (LTDEA). The reagent appears to be milder than LTDEA. Nevertheless, the reducing action of STDEA is very similar to that observed previously for LTDEA, as is the case of the corresponding parent sodium and lithium aluminum hydrides. STDEA shows a unique reducing characteristics. Thus, benzyl alcohol, phenol and 1-hexanol evolved hydrogen slowly, whereas 3-hexanol and 3-ethyl-3-pentanol, secondary and tertiary alcohols, were essentially inert to STDEA. Primary amine, such as n-hexylamine, evolved only 1 equivalent of hydrogen slowly. On the other hand, thiols examined were absolutely stable. STDEA reduced aidehydes and ketones rapidly to the corresponding alcohols. The stereoselectivity in the reduction of cyclic ketones by STDEA was similar to that by LTDEA. Quinones, such as p-benzoquinone and anthraquinone, were reduced to the corresponding 1,4-dihydroxycyclohexadienes without evolution of hydrogen. Carboxylic acids and anhydrides were reduced very slowly, whereas acid chlorides were reduced to the corresponding alcohols readily. Esters and epoxides were also reduced readily. Primary carboxamides consumed hydrides for reduction slowly with concurrent hydrogen evolution, but tertiary amides were readily reduced to the corresponding tertiary amines. The rate of reduction of aromatic nitriles was much faster than that of aliphatic nitriles. Nitrogen compounds examined were also reduced slowly. Finally, disulfide, sulfoxide, sulfone, and cyclohexyl tosylate were readily reduced without evolution of hydrogen. In addition to that, the reagent appears to be an excellent partial reducing agent: like LTDEA, STDEA converted ester and primary carboxamides to the corresponding aldehydes in good yields. Furthermore, the reagent reduced aromatic nitriles to the corresponding aldehydes chemoselectively in the presence of aliphatic nitriles. Consequently, STDEA can replace LTDEA effectively, with a higher selectivity, in most organic reductions.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제25권3호
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• pp.57-65
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• 2019

Purpose: The purpose of this study is to find the relationship between Michell Foucault's the primary, secondary, and tertiary spatialization of disease and spatial composition for the development of architectural planning of the healthcare architecture. Methods: Literature review of spatialization of disease and comparison between medical and dental disease have been conducted. The synchronic structure and diachronic change of spatialization process have been analyzed through spatial composition and history of Seoul National University, School of Dentistry and Dental Hospital. Results: The result of this study can be summed up in three points. First of all, spatialization of dental disease is similar to that of medicine but it should be more focused on the tertiary spatialization. The second one is that the process of spatialization of dental disease started the secondary spatialization first and the primary spatialization followed after a short interval and spatial composition has been followed the process of spatialization of dental disease in Korea. The third one is that the tertiary spatialization has not been actively gone along until recently and it has to be developed in near future. Implications: It is necessary to analyze spatialization of dental disease in other dental facilities to develop the relationship between spatial composition and program in healthcare system.

• 농촌계획
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• 제25권2호
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• pp.63-74
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• 2019

As the awareness of food security has increased, the Korean government has established national projects, such as Saemangeum proclaimed land, to secure sources of grain. Saemangeum is a large-scale agricultural area that was constructed to maintain preparedness for unstable food markets. This study aims to develop a $6^{th}$ Industrialization Model (SIM) for Saemangeum Grain Complex by applying feasible strategies to wheat and two-rowed barley which have low self-sufficiency rates. In addition, this study estimates the potential economic value of each development strategy associated with a sixth industrialization model to create higher added values from production, processing and tourism experiences. The strategic plan for primary, secondary, and tertiary industries is to combine cultivating and processing wheat and two-rowed barley for sales and linking them to tourism experience. This study shows value added from the combination of the primary, secondary and tertiary industry of wheat and two-rowed barley are 7.5 and 23.0 times more than those of the primary and tertiary industry combination, respectively. Through branding Saemangeum Grain Complex's products, such as Saemanguem bread and craft beer, would further enhance the economic benefits derived from the complex.

• 한국물환경학회지
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• 제27권6호
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• pp.877-884
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• 2011

In this paper, the removal characteristics of dissolved organic carbon (DOCs) by micro bubble ozonation process and $O_3/UV$ process were comparatively studied. In the point of DOC removing reaction coefficient, micro bubble ozonation system and $O_3/UV$ process had not significant difference, $0.0120sec^{-1}$ and $0.0141sec^{-1}$. Therefore micro bubble ozonation process is more suitable for tertiary treatment of sewage in the point of installation and maintenance cost-reducing. The optimum ozone injection rate was 2.0 g $O_3/g$ DOC and HRT was 3 min for the micro bubble ozonation process. The removal efficiency of DOC and SUVA in micro bubble ozonation system was 32.8% and 58.3% respective. Biological aerated filter (BAF) process was installed to remove soluble organic material increased by micro bubble ozonation system. And the effluent BOD of BAF was below 1.0 mg/L. In the view of cost-effectiveness, $O_3/BAF$ process was more profitable than $O_3/UV/BAF$ process for tertiary treatment of sewage. In order to nitrify ammonia in the BAF process completely, $NH_4{^+}-N$ concentration in the influent water of BAF should be designed considering low water temperature in the winter season.