• Bulletin of the Korean Chemical Society
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• v.19 no.5
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• pp.569-575
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• 1998

Investigation of the structure of the gangliosides has proven to be very important in the understanding of their biological roles. We have determined the tertiary structure of asialoganglioside GM1 $(GA_1)$ using NMR spectroscopy and distance geometry calculations. All of the structures are very similar except the glycosidic torsion angles in the ring IV and ring III linkages. There are two low-energy structures for GA1, G1 and G2. G1 differs from G2 only in the IV-III glycosidic linkages and the orientation of acetamido group in ring III. There is a stable intramolecular hydrogen bond between the third hydroxyl group in ring I and the ring oxygen atom in ring II. Also, there may be a weak hydrogen bond between the second hydroxyl group in ring IV and the acetamido group in ring III. Small coupling constants of $^3J_{IH3,IOH3}\; and\; ^3J_{IVH2,IVOH2}$ support this result. Overall structural features of $(GA_1)$ are very similar to those of $(GM_1)$. It implicates that specificities of the sugar moieties in GM1 are caused not by their tertiary foldings, but mainly by the electrostatic interactions between the polar sialic acid and its receptors. Since it is evident that $(GA_1)$ is more hydrophobic than $(GA_1)$, a receptor with a hydrophobic binding site can recognize the $(GA_1)$ better than $(GA_1)$. Studies on the conformational properties of $(GA_1)$ may lead to a better understanding of the molecular basis of its functions.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.10
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• pp.259-267
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• 2021

Both structural transformation and education are the predominant subjects in the literature of development economics. This study examines the relationship between education before the tertiary level and the structural transformation of provinces by using Vietnam as a case study. In this study, education before the tertiary level would be disaggregated into three groups: primary, lower secondary, and upper secondary, then analyzed simultaneously on three-panel data models. Research data is taken from the statistical yearbook of provinces in Vietnam for 2015-2018. Research results show that education before the tertiary level plays a vital role in structural transformation. The enrolment rate of various education levels has a different influence on economic structure, and the lower secondary level has more significant effects than the upper secondary level. This reflects that participating in lower secondary is a fundamental requirement for taking some jobs in the non-agriculture sector, while upper secondary helps to upgrade the learner's abilities to respond to higher requirement jobs. The high rate of repeaters in upper secondary education will slow down the structural shift towards non-agriculture, and changing the traditional attitude about repeaters plays an essential role in improving this rate.

• International Journal of Knowledge Content Development & Technology
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• v.9 no.2
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• pp.7-31
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• 2019

This study was conducted to investigate the awareness and utilization of the Internet resources and services for academic activities by the academic staff of tertiary institutions in Adamawa State. The researchers adopted a quantitative research method using cross-sectional survey design to collect data from the respondents. Multi-stage sampling techniques were used. Three hundred and thirty-three (333) copies of the questionnaire were administered to the respondents in the eight (8) sampled institutions and two hundred and ninety-two (292) respondents representing (87.6%) were returned and found useful. The data collected were analyzed using descriptive and inferential statistics by the use of SPSS version 20.0. The findings revealed that respondents were aware of all the Internet resources, (e-books, e-journals, and online databases), but regarding the Internet services, they were mostly aware of only the e-mail. The study further found that online database and e-mail as the most Internet resources and services utilized by the respondents. There are inverse and weak relationship between awareness and utilization of the Internet resources and services by the academic staff of tertiary institutions in Adamawa State. The study recommends increase awareness and use to other Internet resources such as the e-books and e-journal and Internet services, especially Usenet, Discussion group and Telnet by the management of the institutions through training, workshops/conferences for better academic activities.

• Journal of Korean Critical Care Nursing
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• v.12 no.1
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• pp.57-70
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• 2019

Purpose : The purpose of this study was to identify the risk factors for falls in tertiary hospital inpatients and to suggest data for developing a nursing intervention program for preventing falls. Methods: Data were collected between January 1, 2017, to December 31, 2017. Kaplan-Meier estimation was used to measure the survival rate, and the log-rank test was used for the differences between the fall group and the non-fall group. The Cox proportional hazards model was used to identify the risk factors for falls. Results: The incidence rate of falls for the inpatients was 1.2 cases per 1,000 days of hospitalization. The risk factors for falls were more likely to be found among those who were aged ${\geq}81$, had not undergone surgery, had poor joint motion, had unsteady gait, needed help or supervision, used assistive devices, had comorbidity, and took at least two drugs. Conclusion: For the inpatients, the risk factors for falls included age, surgery, comorbidity, medication that could change mobility, joint motion, and use of patient care equipment. It is necessary to give special attention to inpatients who have any of these risk factors and to develop a falls risk assessment tool.

• Journal of Positioning, Navigation, and Timing
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• v.11 no.3
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• pp.147-156
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• 2022

In this paper, we propose Time-Division-Multiplexing Tertiary Offset Carrier (TDMTOC), a novel GNSS modulation based on Tertiary Offset Carrier (TOC) modulation. The TDMTOC modulation multiplexes two three-level signals (i.e., -1, 0, and 1) while crossing over time, and is a type of TOC modulation designed specifically for signal multiplexing. The proposed modulation generates TDMTOC subcarriers of two different phases by simply combining two Binary Offset Carrier (BOC) subcarriers by addition or subtraction. TDMTOC has better correlation and spectral properties than conventional BPSK, BOC, and MBOC modulation techniques, and has good power and spectral efficiency since it can multiplex signals without power loss similar to time division multiplexing. To prove this, we introduce the multiplexing process of TDMTOC, and compare TDMTOC with Binary Phase Shift Keying (BPSK), BOC, Composite BOC (CBOC), and Time Multiplexed BOC (TMBOC) that are currently serviced in GNSS by simulations of various aspects. Through the simulation results, we prove that TDMTOC has better correlation property than modulations currently used in GNSS, less intersystem interference due to its wide spectrum property, and robustness in multipath and noise channel environments.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.2
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• pp.141-146
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• 2023

The efficient use of a chiral shift agent (3) containing bifunctional group (thiourea and tertiary amine) for the determination of the enantiomeric purity of racemic mixture (Hemiesters) has been studied. The diastereomeric complexes derived from a chiral shift agent (3) with various hemiesters gave rise to well separate signals of the methoxy protons of hemiesters. Good splitting signals for enantiomers of hemiesters in ¹H NMR are originated form the hydrogen bonds between carbonyl groups of hemiester and bifunctional groups of a chiral shift agent (3) such as thiourea moiety and tertiary amine. This study provides a quick and simple way to determine the chiral purity of hemiester using chiral transfer agent (3).

• Journal of Korean Clinical Nursing Research
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• v.29 no.3
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• pp.327-336
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• 2023

Purpose: This study aimed to identify the factors affecting the practice of medical waste management of nurses in tertiary general hospitals after the coronavirus disease 2019 (COVID-19). Methods: The participants were 154 nurses working in two tertiary general hospitals. Data were collected using structured questionnaires and analyzed using an Independent t-test, One-way ANOVA, Scheffé test, Pearson correlation coefficients, and multiple regression analysis using the SPSS/WIN 27.0 program. Results: Factors significantly influencing the subject's practice of medical waste management include medical waste education(β=.18, p=.013), recognition of infection control organizational culture (β=.26, p=.007), and attitudes toward medical waste management (β=.23, p=.011). The explanatory power of these variables for medical waste management practice was 29.0% (F=7.34, p<.001). Conclusion: To improve the practice of medical waste management, a strategy to provide positive attitudes toward medical waste management should be needed when developing medical waste management training programs, and various measures are necessary to make the organizational culture positive for the implementation of infection control guidelines at the organizational level.

• Journal of Home Health Care Nursing
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• v.31 no.1
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• pp.56-65
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• 2024

Purpose: This study aimed to explore the association between demographic characteristics, hospitalization-related characteristics, and the severity of long-term hospitalization in a high-level general hospital, and to analyze the factors influencing decisions of all patients. Methods: General and clinical characteristics of the participants were analyzed using frequency, percentage, mean, and standard deviation. Differences in these characteristics, contingent upon whether a power source was requested, were analyzed using independent t-Test and Chi-squared tests. Logistic regression analysis was used to identify the factors related to the presence or absence of power requests. Results: The factors impacting the decision to refer a dependent variable include medical treatment (neurosurgery) (B=2.118, SE=0.960, p-value=.027, OR=8.314, 95% CI=1.267-54.551), infection isolation (CRE) (B=1.336, SE=0.666, p-value=.045, OR=3.804, 95% CI=1.032-14.021), and the utilization of tertiary antibiotics (B=3.076, SE=1.362, p-value= .024, OR=21.663, 95% CI=1.502-312.530). Conclusion: This study found a significant association between medical treatment (neurosurgery), infection isolation (CRE), and the use of tertiary antibiotics as dependent variables. These findings indicate that continuous monitoring can contribute to a reduction in long-term financial burdens.

• Journal of Information Technology Applications and Management
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• v.30 no.1
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• pp.81-95
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• 2023

As the DT of micro businesses emerges as an important task, the government is also promoting support projects such as policy establishment and micro business education. This study aims to develop a new index (checklist) that can objectively measure the level of digital literacy required for DT in the tertiary industry, which accounts for the largest share of micro business owners. In this study, indicators were derived through review of existing studies and FGI, and the validity and reliability of Likert 5 were measured for decision makers in the tertiary industry. In the field of digital literacy for micro business owners, a total of 22 indicators were developed, largely composed of basic technology environment competency, information utilization competency, information dissemination and production capability, and mind recognition capability. This study has academic significance in that it can contribute to accurately understanding the digital capabilities of micro business owners by developing a digital literacy index for micro business owners, a specific group lacking in research.

• Journal of muscle and joint health
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• v.31 no.2
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• pp.86-94
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• 2024

Purpose: The goal of this study aimed to understand the factors influencing the empathy competence and moral sensitivity of nurses working in tertiary general hospitals who offered end-of-life care. Methods: Descriptive data were collected from self-reported questionnaires completed by 164 nurses with direct nursing care experience with end-of-life patients at two tertiary general hospitals located in Busan, Korea. The variables examined were empathy competence, moral sensitivity, and end-of-life care performance. Data were analyzed using SPSS version 27.0 software. Results: Participants scored 3.73±0.40 on empathy competence, 4.97±0.51 on moral sensitivity and 2.91±0.37 on end-of-life care performance. There was a significant positive correlation between empathy competence and end-of-life care performance, and between moral sensitivity and end-of-life care performance. The factors affecting nurses' end-of-life care performance, empathy competence and moral sensitivity, exhibited with an explanatory power of 31%. Conclusion: Programs to increase empathy competence and moral sensitivity should be developed to improve nurses' end-of-life care performance.