• Journal of Chest Surgery
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• 제33권6호
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• pp.521-524
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• 2000

The benign teratoma is usually slow growing tumor, but we expirienced a case of primary huge mediastinal benign teratoma that had grown very rapidly, maximally during 3 years. The 14-year-old female patient was admitted to our hospital because of abnormal chest X-ray that showed 10$\times$10cm sized well definded mass with multiple calcificactions. but the mass was not present in chest X-ray perfomed on 3 years prior to admission. Under the diagnosis of teratoma, complete surgical resection was done by the left thoracotomy. The result of pathology was benign teratoma.

• 동의생리병리학회지
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• 제24권6호
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• pp.1059-1061
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• 2010

Mature cystic teratoma is a common ovarian lesion, approximately 10-20% of ovarian tumor. However, it can undergo a malignant transformation, but incidence of malignant transformation is very low. Squamous cell carcinoma is the most common type of malignant transformation in the mature cystic teratoma. Preoperative diagnosis of malignant transformation in the mature cystic teratoma is very difficult, because malignant transformed tissues are very small in the mature cystic teratoma components. And so most of the carcinoma arising in mature cystic teratoma were diagnosed after histologic examination. We experienced a case of squamous cell carcinoma arising in the mature cystic teratoma of the ovary and report a case with a brief review of the literatures.

• Journal of Yeungnam Medical Science
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• 제20권1호
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• pp.92-98
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• 2003

Testicular teratoma is characterized that has more than one germ cell layer in various stages of maturation and differentiation. The incidence of mature teratoma varies from 2 to 9% of all germinal testicular tumor. Only 3 cases of bilateral teratoma have been reported in the literature to date. The teratoma can occurs at all ages but is most common between the age of 15-35 year. It is relatively infrequently seen in childhood and infancy. In these age group, teratoma tends to be a benign. Recently, we experienced one case of bilateral testicular teratoma in 4 month-old infancy. We report a case of bilateral testicular teratoma found infancy with review of related literatures.

• Journal of Chest Surgery
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• 제42권3호
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• pp.355-360
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• 2009

배경: 양성 기형종은 대부분은 무증상이지만 적은 빈도에서 늑막, 심외막, 폐실질, 기관지 내로 파열 되어 심한 증상 유발과 함께 치료가 어려워 술 전 파열여부에 대한 정확한 진단이 수술적 치료에 있어서 중요하다. 따라서, 이 연구에서는 파열된 양성 기형종의 임상적 증상, 영상학적 소견과 수술적 소견에 대해서 알아보고 파열되지 않은 기형종과의 차이를 알아 보고자 하였다. 대상 및 방법: 24명의 완전 절제된 양성 기형종의 환자를 후향적으로 조사하였다. 수술 전 임상 증상, 흉부 CT 소견, 수술 소견과 수술 성적의 차이를 파열된 군과 파열되지 않은 두 군에서 비교하였다. 특히 흉부 CT 소견에서는 종괴 크기, 피막 두께, 종괴의 위치, 분엽 정도, 균일성, 종괴 내용물, 주위 장기와의 관계 등을 조사하였다. 결과: 총 24명의 환자에서 수술 소견 결과, 7명의 환자(29.2%)가 파열된 양성 기형종으로 진단되었다. 15명(62.5%)의 환자에서 술 전 흉통, 기침 등의 증상이 있었으며 파열된 양성 기형종에서 증상이 심하고 빈도가 높았으나 통계적으로 차이는 없었다(p=0.37). 흉부 CT 소견에서는 두 군간에 종괴의 크기, 피막 두께, 종괴의 위치, 분엽정도, 균일성에는 차이가 없었다. 하지만 석회화 정도와(p=0.04), 종괴 주변 소견으로 폐경화, 폐허탈의 빈도가 파열 양성 기형종에서 통계적으로 유의하게 높았다(p=0.03). 파열된 양성 기형 종에서 수술적 접근은 모두 흉골 절개 또는 개흉술을 통해서 이루어 졌으며 동반된 폐절제 건수도 많았다. 결론: 술 전 흉부 CT는 파열된 기형종을 정확하게 진단할 수 있었고, 종괴 내에 석회화가 존재하거나 폐병변이 동반된 경우 파열된 기형종의 확률이 높았다. 따라서, 술 전 임상 소견 및 흉부 CT 소견에 의한 정확한 진단은 적절한 수술적 시기를 정하거나 접근 방법을 정하는 데에도 중요한 역할을 할 것으로 생각된다.

• 한국임상수의학회지
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• 제13권1호
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• pp.74-76
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• 1996

A case of ovarian teratoma is reported in a 11-year-old female Korean Jindo dog. Grossly, the left ovary was markedly enlarged ($5{\times}4{\times}4 cm in size$) and contained several cystic spaces filled with hairs and yellowish, fragile deratinous material on cross section. Histological observation of the hair and keratin containing cystic structures lined by stratified squamous epithelium, mature adipose tissue, and bone and cartilage is compatible with a diagnosis of ovarian teratoma, pyometra was also present in this dog. This is believed to be the first report on canine ovarian teratoma in Korea.

• Journal of Chest Surgery
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• 제23권6호
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• pp.1270-1274
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• 1990

In mediastinum, teratoma frequently occur in anterior mediastinal compartment. Rarely discovered in pericardium, posterior mediastinum and lung parenchyme. The incidence of posterior mediastinal teratoma was 3%~8%. A young male patient was treated with posterior mediastinal teratoma. So we describe the rare disease.

• Journal of Chest Surgery
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• 제28권6호
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• pp.644-648
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• 1995

Intrapulmonary teratoma is rare : only 30 cases have been reported in the world literature. We had experienced a case of benign intrapulmonary teratoma originated from anterior mediastinum associated with broncho-tumorous fistula, which was treated with En bloc removal of tumor and right middle lobectomy. Post-operative course was not eventful.

• Journal of Yeungnam Medical Science
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• 제18권2호
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• pp.293-296
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• 2001

Mature cystic teratomas, commonly called dermoid cysts, are the most common benign germ cell tumors of ovary in women of reproductive age. Mature cystic teratoma that constitutes 10-25% of ovarian tumors and 95% of teratoma, is germ cell tumor of the ovary. This occurs frequently in women less than 20 years old, but it can be found upto 10-20% in postmenopausal women. And in women over the age of 50, a mature cystic teratoma is likely to change into malignant form. Traditional surgical methods of mature cystic teratoma treatment include transabdominal cystectomy, oophorectomy, hysterectomy and(or) bilateral salphingooophorectomy. Recently laparoscopic approach replaces transabdominal surgeries in many cases. Vaginal removal of mature cystic teratoma is unique and rare. Compared with laparotomy, transvaginal approach is characterized by shorter hospital stay and lower morbidity rate. Compared with laparoscopic operation, transvaginal approach has advantages of no visible operative scar and lower intra-operative tumor spillage. The decision for surgical methods is related with patients' situations and surgeon's preference. We report 1 case of vaginal removal of mature cystic teratoma as a part of vaginal hysterectomy in old age patient.

• Advances in pediatric surgery
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• 제9권2호
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• pp.94-97
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• 2003

The teratoma is a unique complex neoplasm and is one of the most frequent pediatric tumors originated from the extragonadal germ cells. Mature teratoma is composed of mature differentiated tissues, while immature teratoma always contains embryonic tissues of variable degrees of immaturity, especially in the neuroepithelial elements. Diagnosis of teratoma is relatively easy by conventional radiologic study, but the immaturity can be identified only by histopathological examination. Between January 1993 to December 2002, 63 cases of teratoma were operated and analysed retrospectively at the Chonnam University Hospital Female to male ratio was about 3:1 and age distribution was relatively even. Among 63 cases, gonadal teratoma was the most common (52.4%), followed by sacrococcygeal (25.4%), retroperitoneal (9.5%) and mediastinal teratoma (9.5%). Fifty-six cases were mature teratomas and seven were immature teratomas. Alpha-fetoprotein (AFP) was elevated in 4 of 6 immature cases, but in 2 of 51 mature ones Elevated AFP progressively returned to normal range by 1 month after operation in all. Complete excision of the mass was performed, and major complication was not noticed. In five immature cases, PEB chemotherapy (Cisplatin, Etoposide, Bleomycin) was performed. Two of 2 cases in histological grade II were well tolerated to the aggressive chemotherapy. One of three cases in grade III expired due to severe bone marrow depression, and two of them expired by tumor recurrences. In conclusion, immature teratoma in histological grade III showed high potentiality of recurrence. Therefore, postoperative chemotherapy has to be applied to the high graded immature tumors.

• 한국연초학회지
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• 제13권1호
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• pp.36-42
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• 1991

The present study was conducted to obtain some basic information on the shoot formation from crown gall callus and the characteristics of teratoma shoot derived from crown gall induced by inoculation of Agrobacterium tumefaciens C58. Crown gall callus could be continuously cultured on the phyohormone free basic medium. The growth of crown gall callus was inhibited when BA were added to the cultural media. Shoot formation from crown gall callus fail to be initiated except teratoma shoot which induced on the phytohormone free medium after several subculture on rare occasions. Teratoma shoot could not form root and grow as normal shoot. Addition of BA to cultural media was not effective for shoot elongation, reduction in multiple shoot formation, but IBA was somewhat effective for shoot elongation of teratoma shoot, never for root formation.