Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Case of Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary - A case report -

난소의 성숙기형종에서 발생한 편평세포암종 - 1예 보고

  • Jo, Hyang-Jeong (Department of Pathology, Kunsan Medical Center, Wonkwang University) ;
  • Moon, Hyung-Bae (Department of Pathology School of Medicine, Wonkwang University)
  • 조향정 (원광대학교 군산의료원 병리과) ;
  • 문형배 (원광대학교 의과대학 병리학교실)
  • Received : 2010.11.15
  • Accepted : 2010.12.10
  • Published : 2010.12.25
Download PDF
⟨ Previous Next ⟩

Abstract

Mature cystic teratoma is a common ovarian lesion, approximately 10-20% of ovarian tumor. However, it can undergo a malignant transformation, but incidence of malignant transformation is very low. Squamous cell carcinoma is the most common type of malignant transformation in the mature cystic teratoma. Preoperative diagnosis of malignant transformation in the mature cystic teratoma is very difficult, because malignant transformed tissues are very small in the mature cystic teratoma components. And so most of the carcinoma arising in mature cystic teratoma were diagnosed after histologic examination. We experienced a case of squamous cell carcinoma arising in the mature cystic teratoma of the ovary and report a case with a brief review of the literatures.

Keywords

References

  1. Hirakawa, T., Tsuneyoshi, M., Enjogi, M. Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Clinicopathologic and topographic analysis. Am J Sur Pathol 13: 397-405, 1989. https://doi.org/10.1097/00000478-198905000-00007
  2. Peterson, W.F. Malignant degenerationof benign cystic teratomas of the ovary. A collective review of the literature. Obstet Gynecol Surv 12: 793-830, 1957. https://doi.org/10.1097/00006254-195712000-00001
  3. Kikawa, F., Ishikawa, H., Tamakoshi, K., Nawa, A., Suqanuma, N., Tomoda, Y. Squamous cell carcinoma arising from mature cystic teratoma of the ovary: A clinicopathologic analysis. Obstet Gynecol 89: 1017-1022, 1997. https://doi.org/10.1016/S0029-7844(97)00117-8
  4. Davis, G.L. Malignant melanoma arising in mature cystic teratoma (dermoid cyst). Report of two cases and literature analysis. Int J Gynecol Pathol 15: 356-362, 1996. https://doi.org/10.1097/00004347-199610000-00009
  5. Climie, A.R., Heath, L.P. Malignant degeneration of benign cystic teratoma of the ovary. Review of the literature and report of a chondrosarcoma and carcinoid tumor.
  6. 박미선, 서민정, 최주혁, 윤주희, 박동춘. 난소의 성숙 낭성 기형종에서 발생한 육종 1예. 대한산부회지 50: 1414-1420, 2007.
  7. 홍 란, 임성철, 송창훈, 기근홍, 이미자. 난소 복합기형종의 갑상샘증에서 발생한 유두암. 대한산부회지 50: 1552-1557, 2007.
  8. Pantoja, E., Ibanez, I.R., Axtmayer, R.W., Noy, M.A., Pelegrina, I. Complication of dermoid tumors of the ovary. Obstet Gynecol 45: 89-95, 1979.
  9. Masamichi, K., Shinohara, M. Clinicopathologic study of squamous cell carcinoma of the ovary. Gynecol Oncol 34: 75-79, 1989. https://doi.org/10.1016/0090-8258(89)90111-X
  10. Lee, Y.C., Abulafia, O., Montalto, N. Malignant transformation of an ovarian mature cystic teratoma presenting as a rectal mass. Gynecol Oncol 75: 499-503, 1999. https://doi.org/10.1006/gyno.1999.5602
  11. Tseng, C., Chou, H., Huang, T., Liang, C. Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Obstet Gynecol 78: 562-565, 1991.
  12. Griffiths. D., Wass, J., Look, K., Sutton, G. Malignant degeneration of a mature cystic teratoma, five decades after discovery. Gynecol Oncol 59: 427-429, 1995. https://doi.org/10.1006/gyno.1995.9948
  13. Sebaggi, S.M. Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Arch Pathol Lab Med 124: 477-482, 2000.
  14. Scamp, G.W., McConnell E.M. Malignancy arising in cystic ovarian teratomas. A report of 24 cases. Br J Obstet Gynecol 90: 671-675, 1983. https://doi.org/10.1111/j.1471-0528.1983.tb09289.x
  15. Miyazaki, K., Tokunaga, T., Karabuchi, H., Ohba, T., Tashiro, H., Okamura, H. Clinical usefulness of serum squamous cell carcinoma antigen for early detection of squamous cell carcinoma arising in mature cystic teratoma of the ovary. Obstet Gynecol 78: 562-566, 1991.
  16. Kimura, T., Inoue, M., Miyake, A., Tanizawa, O., Oka, Y., Amemiya, K. et al. The use of serum TA-4 in monitoring patients with malignant transformation of ovarian mature cystic teratoma. Cancer 64: 480-483, 1989. https://doi.org/10.1002/1097-0142(19890715)64:2<480::AID-CNCR2820640222>3.0.CO;2-7
  17. Suzuki, M., Kobayashi, H., Seckiguchi, I., Konnai, K., Terao, T., Sato, I. Clinical evaluation of squamous cell carcinoma antigen in squamous cell carcinoma arising in mature cystic teratoma of the ovary. Oncology 52: 287-290, 1995. https://doi.org/10.1159/000227475
  18. 김민정, 남은지, 김재욱, 김영태, 김재훈, 김성훈 등. 난소의 성숙낭성 기형종에서 기원한 편평세포암의 임상병리학적 고찰. 대한산부회지 49: 1455-1462, 2006.
  19. Kurtz, J.E., Jacck, D., Malosel, F., Jung, G.M., Chenard, M.P., Dufour, P. Combined modality treatment for malignant transformation of a benign ovarian teratomas. Gynecol Oncol 73: 319-321, 1997.
  20. Rose, P.G., Tak, W.K., Reale, F.R. Squamous cell carcinoma arising in a mature cystic teratoma with metastasis to the paraaortic nodes. Gynecol Oncol 50: 131-133, 1993. https://doi.org/10.1006/gyno.1993.1178
  21. Kikawa, F., Nawa, A., Tamakoshi, K., Ishikawa, H., Kuzuya, K., Suganuma, N., et al. Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary. Cancer 82: 2249-2255, 1998. https://doi.org/10.1002/(SICI)1097-0142(19980601)82:11<2249::AID-CNCR21>3.0.CO;2-T