• 제목/요약/키워드: Tensilon test

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중증 근무력증 진단에 있어서 제반 검사법들의 유용도 비교 (Comparison of Usefulness of Laboratory Tests in Diagnosis of Myasthenia Gravis)

  • 박승권;도현철;김민정;이승엽;박미영;하정상;김욱년;이준
    • Journal of Yeungnam Medical Science
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    • 제15권1호
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    • pp.125-134
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    • 1998
  • 1993년 1월 1일부터 1995년 6월 30일 까지 영남대학교 의과대학 부속병원 신경과에 중증 근무력증 증상을 주소로 내원한 환자 중 21명에게 텐실론검사, 반복신경자극검사, 단일근섬유 근전도 검사 및 아세틸콜린 수용체에 대한 항체 측정 검사 모두를 시행하여 각 검사의 양성률을 구하여 비교하였다. 텐실론검사에서는 양성률이 95%였고, 반복신경자극검사상 최초 한 근육이상에서 양성률을 보인 경우가 67%였고 근육별로는 안윤근에서 67%, 척측수근굴근에서 38%, 소지외전근에서 43%로 원위근육에 비해 안윤근에서 더 높은 양성률을 보였으나 통계학적인 유의성은 없었다. 한편 단일근 섬유 근전도검사, 아세틸콜린 수용체에 대한 항체 측정 양성률은 각각 87%, 76%로 텐실론검사에서 양성률이 가장 높았고, 안형에서 시행한 반복신경자극검사에서는 양성률이 45%로 가장 낮았다. 또 각각의 검사들을 안형군과 전신형으로 나누어 양성률을 비교하였을 때 모두 안형에 비해 전신형에서 양성률이 증가된 소견을 보였으나 반복 신경자극검사에서만 유의성있게 양성률이 증가하였고(p<0.05) 나머지 검사들에서는 통계학적 유의성이 없었다. 이상의 결과로 볼 때 중증 근무력중 증상이 보이는 환자에게서 우선적으로 양성률이 가장 높은 텐실론검사를 먼저 실시한 후, 반복신경자극검사와 함께 특이성을 높일 수 있도록 아세틸콜린 수용체에 대한 항체를 측정하고, 비교적 양성률이 낮은 안형에서는 단일근섬유 근전도검사를 같이 시행하면 중증 근무력증에 대한 확진률을 높일 수 있으리라고 사료된다.

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견사의 탄성적성질에 관한 연구 II. 인장속도 및 팽윤에 따른 파괴강신도의 변화 (Reological Studies on Cocoon Filament II. Changes of strength and elongation at breaking related to the stretching speed and swelling degree)

  • 남중희
    • 한국잠사곤충학회지
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    • 제14권2호
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    • pp.105-112
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    • 1972
  • 팽윤견사를 수중에서 인장시킬 경우, 인장속도 및 팽윤정도의 차이가 견사의 하중신장곡선에 미치는 영향을 조사하였다. 인장시험은 Tensilon을 사용하였고, 절단시 강도, 신도 및 인장저항도를 조사한바 다음과 같은 결과를 얻었다. 1. 팽윤견사의 절단강도는 인장속도의 증가와 더부러 높아지나 절단신도는 감소하였다. 2. 견사를 팽윤(90$^{\circ}$, 15분)시켜 저속(4mm/분)으로 인장하면 견사의 macrofibril의 분리절단상태가 chart 상에 기록되었다. 3. 9$0^{\circ}C$로 장시간 팽윤처리(60분)하면 절단강도는 현저히 감소하고, 절단신도는 증가의 경향을 보였다. 4. 초기인장저항도는 인장속도 및 팽윤정도의 차이에 의하여 영향된다. 즉 고속인장은 초기인장저항도를 높이지만 팽윤도의 증가는 감소시켰다.

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흉선절제에 의한 근무력증 치료 2례 보고 (Thymectomy in Myasthenia Gravis: 2 cases report)

  • 이길노
    • Journal of Chest Surgery
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    • 제13권4호
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    • pp.490-494
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    • 1980
  • Myasthenia gravis is a neuromuscular disorder manifested by fatigability and weakness of voluntary muscles. The basic defect in the myasthenia is reduction of available acetylcholine receptors at neuromuscuiar junctions by an autoimmune attack. Removal of the thymus gland now play an Important role in the management of this disease. We have two experiences of thymectomy for myasthenic patients. The 31-year-old housewife(J.H) was admitted to the Taegu Presbyterian Medical Center because of bilateral ptosis, mastication and swallowing difficulties. The presence of thymoma was strongly suggested by roentgenographic studies. A 99.8 gm thymoma was removed completely by total thymectomy. On the 2nd postoperative day respiratory failure developed. Tracheostomy was performed and ventilatory assist was given for 3 days. The patient was completely recovered with antichollestrase drug only. C.N. was 17-year-old girl who has the symptoms of bilateral ptosis and diplopia for 3 years. Tensilon test was positive and antichollnestrase was given for several months, but the patient showed no improvement. After thymectomy she was free from myasthenic symptoms with out anticholinestrase drug.

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종격 평활근육종 및 Stevens-Johnson증후군과 동반된 중증 근무력증 1예 (A Case of Myasthenia Gravis Combined with Mediastinal Leiomyosarcoma and Stevens-Johnson Syndrome)

  • 이동국;권영미
    • Annals of Clinical Neurophysiology
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    • 제6권1호
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    • pp.43-47
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    • 2004
  • We report a case of 36-year-old woman with myasthenia gravis (MG) combined with mediastinal leiomyosarcoma (LMS) and Stevens-Johnson syndrome (SJS). She was admitted to ICU with the symptoms of acute onset headache, diplopia, ptosis, dysphagia, general weakness, and respiratory difficulty for several days. Physical examination revealed tachypnea, decreased breath sounds and dullness to percussion in right lower chest. Neurologic examination showed ptosis, diplopia, decreased gag reflexes, and generalized proximal weakness. Laboratory studies revealed increased serum acetylcholine receptor antibodies and positive Tensilon test. Chest CT showed a huge mass in the right middle mediastium but no evidence of thymic enlargement. Mediastinal LMS was diagnosed by ultrasound-guided needle biopsy. The myasthenic symptoms were fluctuated in spite og intravenous immunoglobulin, plasmapheresis, and corticosteroid. During therapy, SJS developed. She died 4 months after the onset of the myasthenic symptoms despite the chemotherapy for LMS.

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Laryngeal Paralysis in a Cat with Malignant Thymoma

  • Hyeona Bae;Il-Hwa Hong;Dong-In Jung;DoHyeon Yu
    • 한국임상수의학회지
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    • 제40권1호
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    • pp.68-72
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    • 2023
  • A 10-year-old castrated male Domestic Shorthair cat visited a veterinary medical teaching hospital for emergency dyspnea. The cat was hypoxic and hypotensive, and stridorous respiration was remarkable. Visual inspection confirmed laryngeal paralysis and a lack of mobility of the left larynx. Megaesophagus, aspiration pneumonia, cranial mediastinal mass, and positive Tensilon test results using neostigmine were observed, indicating acquired myasthenia gravis secondary to thymic neoplasia. After 10 minutes of neostigmine 0.02 mg/kg IV administration, laryngeal paralysis and dyspnea resolved. Histopathlogical examination for the cranial mediastinal mass after surgical resection confirmed malignant thymoma. Here, we report a case of acquired myasthenia gravis in a cat with a malignant thymoma that presented with life-threatening dyspnea due to laryngeal paralysis. Feline laryngeal paralysis is uncommon, and myasthenia gravis, a cause of laryngeal paralysis in cats, has not yet been reported. Myasthenia gravis should be considered in cats with laryngeal paralysis.

견직물의 내광성에 관한 연구 (An Experimental Study on the Lightfast of Silk Fabrics)

  • 박일록
    • 대한가정학회지
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    • 제20권1호
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    • pp.1-10
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    • 1982
  • This experiment was made on the basis of the general observation that silk fabrics is flaccid in sun light. The purpose of this test is to examine efficiency between the processed thread and the unprocessed one after putting the later under the xenon-lit system, which produces continuous spectrum of bright white beam similar to sun light. (i) Color division of silk thread : white, yellow blue (ii) light division and irradiation time : sun lightlongrightarrow210 hrs, Xenonlongrightarrow50,100, 150 hrs. Under the above conditions each object was be tested with and extensometer, TENSILON Type III for the results of (a) the weight-expansibility curve of the silk thread (b) the relationship between cutting in tensity and maximum, weight (c) maximum expansion rate (d) the expansion energy of the tested silk thread (e) the beginning pull-stretch resistance rate of the tested silk thread (f) color difference after processing The results are illustrated in the appropriate tables and figures. Consequently the generalobservation that silk fabrics is flaccid is relevant only in terms of color. So for as Cutting-intensaty is concerned, it turned out to be less flaccid than in color. On the contrary when the untested silk thread was conpared with the xenon-irradiated ones, the latter proved itself to be more flaccid in cutting expansibility than the former. We have learned through this experiment that, after the all rounds of this test, the color tone and chroma of the colored materials remained without significant change, where as their color value changed to a large extent.

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Direct-bonding bracket 의 인장강도(引張?度) (TENSILE STRENGTH OF DIRECT-BONDING BRACKETS)

  • 권오원
    • 대한치과교정학회지
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    • 제12권2호
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    • pp.139-144
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    • 1982
  • 저자(著者)는 3가지 종류(種類)의 bracket을 교정(矯正)을 위(爲)해서 발치(拔齒)한 20개(個)씩의 소구치(小臼齒)에 접착(接着)하여 24시간(時問) 후(後)에 인장강도(引張?度)를 측정(測定)한 결과(結果) 다음과 같은 결론(結論)을 얻었다. foil-mesh base bracket과 photo-etched base bracket의 평균인장강도(平均引張强度)는 통계학적(統計學的)으로 유의(有意)한 차(差)가 없으며, plastic bracket은 인장강도(引張强度) 측정(測定) 시(時) wing의 변형(變形)에 의(依)해서 정확(正確)한 측정(測定) 결과(結果)를 얻을 수 없 었다. 접착제(接着劑)가 떨어진 양상(樣相)은 foil-mesh base bracket과 photo-etched base bracket에서 접착제(接着劑)가 치아(齒牙)와 bracket 에 부분적(部分的)으로 붙어서 떨어진 것이 각기(各其) 50%로 가장 많았고, 접착제(接着劑)가 치아(齒牙)에만 붙어서 떨어진 것 (30%, 35%), 접착제(接着劑)가 bracket에만 붙어서 떨어진 것 (20%, 15%) 순(順)으로 나타났다.

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