• 제목/요약/키워드: Temporary Building

검색결과 217건 처리시간 0.025초

The role of autophagy in the placenta as a regulator of cell death

  • Gong, Jin-Sung;Kim, Gi Jin
    • Clinical and Experimental Reproductive Medicine
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    • 제41권3호
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    • pp.97-107
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    • 2014
  • The placenta is a temporary fetomaternal organ capable of supporting fetal growth and development during pregnancy. In particular, abnormal development and dysfunction of the placenta due to cha nges in the proliferation, differentiation, cell death, and invasion of trophoblasts induce several gynecological diseases as well as abnormal fetal development. Autophagy is a catalytic process that maintains cellular structures by recycling building blocks derived from damaged microorganelles or proteins resulting from digestion in lysosomes. Additionally, autophagy is necessary to maintain homeostasis during cellular growth, development, and differentiation, and to protect cells from nutritional deficiencies or factors related to metabolism inhibition. Induced autophagy by various environmental factors has a dual role: it facilitates cellular survival in normal conditions, but the cascade of cellular death is accelerated by over-activated autophagy. Therefore, cellular death by autophagy has been known as programmed cell death type II. Autophagy causes or inhibits cellular death via the other mechanism, apoptosis, which is programmed cell death type I. Recently, it has been reported that autophagy increases in placenta-related obstetrical diseases such as preeclampsia and intrauterine growth retardation, although the mechanisms are still unclear. In particular, abnormal autophagic mechanisms prevent trophoblast invasion and inhibit trophoblast functions. Therefore, the objectives of this review are to examine the characteristics and functions of autophagy and to investigate the role of autophagy in the placenta and the trophoblast as a regulator of cell death.

부분 무기둥 비계구조 골조 거동에 관한 실험적 연구 (An Experimental Study on the Behavior of Scaffolding System without a Part of Column)

  • 손기상;정희종
    • 한국안전학회지
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    • 제28권4호
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    • pp.66-71
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    • 2013
  • There is a critically structural problem of scaffolding system when one of scaffold columns is remove to be used as a gangway for their temporary office in the structure before finishing all such as an apartment or office building. This is not used to checking to structurally checking at a construction site. This study is to find out which system at a site will be more effective and low-cost-high effectiveness of aluminum ladder, timber ladder, ${\phi}$1/2 inch steel pipe truss with a type of concave, convex warren truss ladders. Theses are structurally tested with horizontal set as a truss type with 1.8 meter long. Concentrated load has been loaded at the upper center of the system and checked its strain at the bottom center, using aluminum-use strain gage and steel-use gauge have been attached concave warren truss with diameter 1/2 inch has 14% stronger than convex truss. Convex truss has almost same strength as an aluminum ladder truss, it is found out.

RC 띠장-철골 보 접합부의 고정도에 따른 SPS 지하복합골조 거동 해석 (Analysis of Behaviors of SPS Underground Composite Frames Considering the Rigidity of RC Wale-Steel Beam Joint)

  • 김승훈
    • 한국구조물진단유지관리공학회 논문집
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    • 제8권3호
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    • pp.243-250
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    • 2004
  • SPS 공법에서 철골보는 가설상태에서 띠장을 지지하는 버팀대로 사용되며, 시공후 구조물에서 휨재의 역할을 한다. 기존 실험연구결과에서 RC 띠장-철골보 접합부는 소정의 휨강성을 갖는다고 보고하고 있다. 본 연구에서는 SPS 공법으로 시공된 지하복합골조에 대하여 RC 띠장-철골보 스터드 접합부의 고정도에 따른 거동을 평가하기 위하여 비선형 해석을 실시하였다. 해석변수는 시공단계, 횡력의 크기, RC 띠장-철골보 접합부의 고정도 등이다. 해석결과에서 골조의 항복과정, 보 중앙부 휨모멘트 및 처짐에 대한 접합부의 고정도의 영향을 보여준다.

BTL 적용 교육시설의 최적 건축공법 평가에 관한 연구 (A Study on Evaluation of Optimal Construction Method of BTL Projects - Focused on Educational Facilities -)

  • 박유영;조봉호;김기현;이춘경;박태근
    • 한국건설관리학회논문집
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    • 제10권3호
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    • pp.22-31
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    • 2009
  • BTL사업 형태로 발주되는 교육시설의 공사에서는 소요 공기 최소화와 임시교사 설치로 인한 별도의 비용 소모, 그리고 학기 중에 학교 사용자들이 겪는 불편사항으로 주무관청, 민간사업자 그리고 학교사용자의 갈등이 깊어지는 문제가 발생하고 있다. 본 연구에서는 이러한 당면 과제를 공법적인 측면에서 해결하고자, 기존 학교 공사에 일반적으로 적용되는 RC공법과 최근 몇 년 사이에 교육시설의 대안공법으로 주목받고 있는 모듈러 공법을 포함한 몇 개의 대안을 설정하고 교육시설의 BTL사업에 적합한 건축공법을 제안하였으며 각 대안에 소요되는 공사비를 산출하고 공사기간을 분석하여 이를 평가하였다.

지반굴착공사에서의 위험요인 선정과 안전관리방안 연구 (Risk Factor Selaction and Safety Management Plan in the Underground Excavation Construction)

  • 원유진;강경식
    • 대한안전경영과학회지
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    • 제21권4호
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    • pp.31-37
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    • 2019
  • When the foundation work of the underground part of the building structure or the excavation work of the civil engineering structure is carried out, there is the earthwork work by the inevitable process. As the economic situation continues to develop, construction in urban areas is becoming bigger and higher in scale due to the expansion of infrastructure and the rescue of urban dwellings in urban areas, and excavation of underground roads is inevitable. Excavation of the underground part may cause problems in the process difficulty and safety of the earthworks due to the complexity and various characteristics of the ground selected without consideration of the ground characteristics and site conditions. In order to complete the required facilities, it is necessary to secure the design and construction of the retaining walls. In order to complete the required construction, It is an important factor satisfying construction period and economical efficiency.

조선후기 산릉의 여성공간, 나인가가(內人假家)의 변화에 관한 연구 (A Study on the Change of NaInGaGa(Female Space) at the Royal Tomb in the Late Joseon Dynasty)

  • 신지혜
    • 건축역사연구
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    • 제21권5호
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    • pp.7-18
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    • 2012
  • On behalf of the royal women, SangGung(尙宮:The head of female servants in the palace) and NaIns(內人: Female servants caring for royal families in the palace) were dispatched in order to attend a funeral at the royal tomb. The NaInGaGa(內人假家) is the temporary building for SangGung and NaIns in the royal tomb. It is comprised of lodgings for them and also workrooms and warehouses to prepare ritual offering for the dead King or Queen. In the early Joseon dynasty, the NaInGaGa was utilized until a funeral at the royal tomb. Since 1674, NaInGaGa for the 3 years-period lamentation was started constructing separately. At these processes, the plan and placement of NaInGaGa was changed. This study based on the SanReungDoGam-EuiGwae (山陵都監-儀軌: The report on constructing royal tomb). The SanReungDoGam-EuiGwae written since 1800 have illustration about NaInGaGa. The illustration and explanation about NaInGaGa become a important clue that make suppose detailed space of NaInGaGa.

지속가능한 신한옥형 공공건축물을 위한 디자인 요소 기초연구 - 서울, 전라도, 경상도를 중심으로 - (Basic Study of new Hanok Style Public Buidings Design Trend Analysis - Focused on Seoul Jeolla-do Gyeongsang-do Region -)

  • 박민영;이현수;임수영
    • KIEAE Journal
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    • 제14권5호
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    • pp.111-116
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    • 2014
  • Han-ok has been forgotten by rapid industrialization, however, recent interest in Korean traditional culture and eco friendly architecture are increasing. Government is also processing various policies and research in Han-ok for historical reasons. Still Han-ok is considered as temporary discover stage not daily space. Moreover, previous weakness of Han-ok made it difficult to supply. There is a need to build new Han-ok style public buildings different from traditional or new Han-ok for revitalization of Han-ok. Moreover, development of new Han-ok style public buildings model are needed for the public which include updated concept and function. From public buildings model development and supply people can visit and explore Han-ok. Therefore Han-ok tradition can be modernized. In addition to this Korean traditional culture and mode of living can be developed and conserved. This research focuses on public buildings of Han-ok supplication and aims design elements and regional trend.

청소년의 집단따돌림 피해경험에 관한 현상학적 연구 (A Phenomenological Study on the Experience of the Group-Bullied among Adolescents)

  • 김순구;이미련
    • Child Health Nursing Research
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    • 제12권3호
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    • pp.377-385
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    • 2006
  • Purpose: This study was to understand the life experiences of adolescents who were the object of group bullying. Method: Data collection and analysis was done by the Colaizzi method. Data were collected by interviewing the participants and by further follow-up observations. Ten adolescents participated in the study. At that time five of them had already overcome the situation, three were still in a difficult situation and the other two participants were in a temporary absence from school. Results: In the analysis 109 significant statements, 31 themes, 12 clusters of themes and 5 categories emerged. The 5 categories are as follows ; feeling inferiority, not being cared for, loneliness, suffering pain and building a relationship and resignation. The 12 clusters of themes are as follows ; dejection, not being sturdy, mal-function of the family, indifference of the society, loneliness, vexation, suffering, grievance, positive intervention of a support system, exertion, harmonizing and abandonment. Conclusions: The results of this study will help professionals to understand these adolescents. Approaching them from the point of view of the whole man, can also be a practical methode for teaching.

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Communication Performance of BLE-based IoT Devices and Routers for Tracking Indoor Construction Resources

  • Yoo, Moo-Young;Yoo, Sung Geun;Park, Sangil
    • International Journal of Internet, Broadcasting and Communication
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    • 제11권1호
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    • pp.27-38
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    • 2019
  • Sensors collect information for Internet of Things (IoT)-based services. However, indoor construction sites have a poor communication environment and many interfering elements that make it difficult to collect sensor information. In this study, a network was constructed between a Bluetooth Low Energy (BLE)-based IoT device based on a serverless IoT framework and a router. This experimental environment was applied to large- and small-scale indoor construction sites. Experiments were performed to test the communication performance of BLE-based IoT devices and routers at indoor construction sites. An analysis of the received signal strength indication (RSSI) graph patterns collected from the communication between the BLE-based IoT devices and routers for different testbed site situation revealed areas with good communication performance and poor communication performance due to interfering factors. The results confirmed that structural components of the building as well as the materials, equipment, and temporary facilities used in indoor construction interfere with the communication performance. Construction project managers will require improved technical knowledge of IoT, such as optimizing the router placement and matching communication between the router and workers, to improve the communication performance for large-scale indoor construction.

재사용 파이프서포트(V2)의 품질관리 향상에 관한 연구 (A Study on Quality Management Improvement of Used Pipe Support(V2))

  • 박종근;최명기
    • 한국안전학회지
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    • 제34권3호
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    • pp.36-41
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    • 2019
  • As the prefabricated shoring system structure, which is a temporary structure, is often collapsed due to various reasons during concrete pouring, and directly affects not only the safety of the workers but also the quality of the final building, it is necessary to ensure the safety. It is considered that the pipe supports which are widely used as the prefabricated shoring materials in the construction site do not satisfy the performance criteria in many cases. Therefore, this study investigated the detailed conditions for satisfying the performance criteria and suggested the factors for improving the quality control level in order to prevent collapse accidents due to pipe supports reused at the construction site, As the results of test in order to understand the effect of the pipe supports (V2), which are being reused in the field, on the performance by factor, the performance was evaluated to be high in case of the small female screw clearance and the supporting pin with 12mm in diameter or larger.