• Mycobiology
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• 제37권3호
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• pp.161-170
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• 2009

Cryptococcus neoformans is a basidiomycete human fungal pathogen that causes meningoencephalitis in both immunocompromised and immunocompetent individuals. The ability to sense and respond to diverse extracellular signals is essential for the pathogen to infect and cause disease in the host. Four major stress-activated signaling (SAS) pathways have been characterized in C. neoformans, including the HOG (high osmolarity glycerol response), PKC/Mpk1 MAPK (mitogen-activated protein kinase), calcium-dependent calcineurin, and RAS signaling pathways. The HOG pathway in C. neoformans not only controls responses to diverse environmental stresses, including osmotic shock, UV irradiation, oxidative stress, heavy metal stress, antifungal drugs, toxic metabolites, and high temperature, but also regulates ergosterol biosynthesis. The PKC(protein kinase C)/Mpk1 pathway in C. neoformans is involved in a variety of stress responses, including osmotic, oxidative, and nitrosative stresses and breaches of cell wall integrity. The $Ca^{2+}$/calmodulin- and Ras-signaling pathways also play critical roles in adaptation to certain environmental stresses, such as high temperature and sexual differentiation. Perturbation of the SAS pathways not only impairs the ability of C. neoformans to resist a variety of environmental stresses during host infection, but also affects production of virulence factors, such as capsule and melanin. A drug(s) capable of targeting signaling components of the SAS pathway will be effective for treatment of cryptococcosis.

• 대기
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• 제29권5호
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• pp.609-614
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• 2019

Cloud seeding experiment has been proposed as a way to alleviate severe air pollution problem because, if successful, artificially produced precipitation through cloud seeding could scavenge out some portion of air pollutants. As a first step to verify the practicality of such experiment, seedability of the clouds observed in Seoul is assessed by examining statistical characteristics of some relevant meteorological variables. Analyses of 9 years of Korea Meteorological Agency Seoul station data indicate that as PM₁₀ mass concentration increases, cloud amount, liquid water path, and ice water path decrease, but the difference between temperature and dew point temperature tends to increase. Such finding suggests that cloud seeding becomes less feasible as air pollution becomes more severe in the Seoul metropolitan area, at least in a statistical sense. For some individual severe air pollution events, however, seedable clouds may exist and indeed cloud seeding experiments can be successful. Therefore, detailed investigation on cloud seedability for individual severe air pollution events are highly required to make a concrete assessment of cloud seeding as a way to alleviate severe air pollution problem.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 동계학술발표대회 논문집
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• pp.578-583
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• 2008

Korea which has change of clear season is using unique heater by the name of On-dol being invented since ancient times. Floor-heating device has no radiator, and generates no noise and dust. It can obtain satisfied heating sense than other heating system in low room temperature. And also it is a pleasant system that equals bottom and top temperature in a room. The purpose of this study is to develop the Floor-heating device using pulsating heat pipe. It propose floor-heating device using pulsating heat pipe of the dry process which alternative polyethylene pipe(low XL pipe) that is used widely to existent floor heating system and produce pilot Experiment and analyzed operation condition and performance of most suitable. In this study, main purpose is to develop floor-heating system using pulsating heat pipe by finding an optimum working condition according to changing ratio and evaluating a performance.

• 설비공학논문집
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• 제1권2호
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• pp.116-127
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• 1989

Research on reheating cooling cycle and its practical application have been made to prevent unequalized distribution of temperature and humidity of room due to lack of supply air volume and dewdrops on supply diffusers to be taken place as a result of lower temperature of supply air than that of dew point of room air in cooling cycle of constant air volume, single duct, single zone and draw-through fan type. In view of the fact that human body is insensitive to humidity, it is possible not only to construct the complete non-reheating cooling cycle by increasing the humidity point allowable with the deduction of occupant's sense of pleasantness minimizing, but also to get cooling cycle decreasing the reheating quantity if the humidity exceeds the point allowable. In addition, it is possible to save maximum 8% in electric energy for cooling in cooling system by constructing non-reheating cooling cycle instead of reheating cooling cycle and by increasing the relative humidity of room from 50% to 65% in case efficiency and air pressure of cooling system are low. It is also possible to get an optimum cooling cycle by determining the room humidity in consideration of pleasantness of occupants and conservation rate of electric energy if the cooling capacity, efficiency and total pressure of cooling equipment are fixed.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2005년도 춘계학술대회 논문집
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• pp.192-198
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• 2005

In this paper, a systematic attempt for estimating geometric dimensions of cold forgings is made by finite element method and a practical approach is presented. In the approach, the forging process is simulated by a rigid-plastic finite element method under the assumption that the die is rigid. With the information obtained from the forging simulation, die structural analysis and springback analysis of the material are carried out. In the springback analysis, both mechanical load and thermal load are considered. The mechanical load Is applied by unloading the forming load elastically and the thermal load is by cooling the increased temperature due to the plastic work to the room temperature. All the results are added to predict the final dimensions of the cold forged product. The predicted dimensions are compared with the experiments. The comparison has revealed that predicted results are acceptable in the application sense.

• 한국정밀공학회지
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• 제9권2호
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• pp.52-60
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• 1992

In this study on the development of the heat flux sensor, unlike the common heat-flux sensor with thermocouple, the heat-treated adhesive-tupe film nickel-gauge was used in measuring temperature. The proposed its Ni-gauge is bound to be compatible with platinum gauge(Pt-Gauge) in its linearity. It is also considered to be cheap in economical sense. In the evaluation of it's performance, the numerical analysis is essential to investigate charateristics of proper sensor and the adequate analsis is depended upon boundary conditions and actual conditions. There are many types of heat flux sensor in the market, and adhexive type flux sensor is most common. In the present investigation, this type of heat flux sensor had been chosen. The figure of the sensor under consideration is an open cavity type, which is calculated numerically by SIMPLER algorithm. The temperature distributions of the sensor predicted by numerical calculation for steady and unsteady states are able to give the chacteristics of the adhesive type heat flux sensor(1st heat flux sensor) according to the heat flux. It means that the outvoltage, the sensitivity, and the performances of responsibility could be evaluated as a result. Through this analysis improved heat flux sensor(2nd heat flux sensor) could be predicted with the reflection of proper operating temperature($150^{\circ}C$) of the Ni-gauge.

• 콘크리트학회논문집
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• 제26권4호
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• pp.449-456
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• 2014

지오폴리머 반응은 매우 복잡하며, 플라이애쉬 화학조성, 입도분포, 자극제 농도와 종류, 양생온도, 양생시간 등이 지오폴리머 물성에 많은 영향을 미치고 있는 것으로 알려져 있다. 이 연구에서는 양생조건이 플라이애쉬 기반 지오폴리머 강도에 미치는 영향을 실험하기 위하여, 양생온도, 고온양생 전 전치시간, 고온에서의 양생시간 등을 변화시켜 양생조건 변화에 따른 지오폴리머 페이스트의 압축강도, SEM, 공극특성 등에 대하여 분석하였다. 실험 결과 양생온도가 높을수록 지오폴리머의 강도는 증가하였으며, 전양생시간이 길어질수록 지오폴리머 강도는 증가되었으나, 고온양생에서의 양생시간이 길어지면 압축강도가 저하현상이 관찰되었다. 고온에서의 양생시간이 길어지면 공극구조의 변화에 따라 강도 저하 현상이 관찰되었다. 따라서 양생온도와 양생시간은 지오폴리머 강도 및 미세구조에 큰 영향을 미치고 있는 것을 확인할 수 있었다.

• 조명전기설비학회논문지
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• 제20권1호
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• pp.7-18
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• 2006

본 연구는 한강교량의 야간경관조명에 관한 조명연출효과를 분석하기 위해 한강교량 8곳을 대상으로 경관조명 현황을 조사하였다. 선행연구를 통해 교량의 경관조명에 있어서 중요한 조명학적물리량 평가요소로 '휘도대비', '색상', '색온도'를 선정하였다. 디지털 광학 계측기인 Radiant Imaging Prometric 1400에 의해 측정된 휘도 색온도 색도분포 등의 물리량 분석결과, '교량의 구조형식' 및 '조명광원'이 한강교량의 야간경관조명의 물리적 특징에 큰 영향을 미치는 요소로 나타났으며, 특히 '교량의 구조형식'에 따라 강조하는 경관조명의 패턴이 유사하게 나타났다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 1998년도 춘계학술발표 논문집
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• pp.255-263
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• 1998

Dust-free garment prevents contamination which otherwise is caused by skin and clothes to protect from dust or dirt. Therefore, it requires high performance and should function as a working clothes. Clothes are a medium between human and thermal environmental system, and it is required to study human enviroment to ensure comfortableness of clothes and to satisfactorily go along with enviroment .This study investigates the physical and physiological features of dust-free garment used in the clean room at a semiconductor factory in oredr to scientifically clarify what the dust-free garmint is as well as to contribute to the design and development of high performance material and clothes. Three kinds of dust-free fabrics (DFG-I, DFG-II, DFG-III) which are being developed by a local company are used to manufacture dust-free garment. These dust-free garments are dressed and tested in such an enviroment as similar to semiconmemts with temperature at 23${\pm}$1$^{\circ}C$ and humidity at 50${\pm}$5%RH in order to investigate the thermo physiological and psychological features of human body. The results of this study are as follows. The results of this study are as follows. 1.The mean skin temperature was significantly different among the clothes, subjects and experimental time. Temperature tends to rise from the time of exercising load. Continuous motion coupled sealed clothes prevents heat transmittance, and temperature rises in the order of DFG-l, DFG-ll and DFG-lll as time course. 2.As for the skin temperature by local timperature is minimun on the head and torso and increares remarkably at the terminal part of human body. 3. As for the body mass loss was significantly higher in DFG-lll than DFG-l and DFG-ll. 4. Though there is no significant difference in the temperature within clothes among the kind of clothes temperature is 1$^{\circ}C$ higher in the back. Temperature within all the dust-free garments 29.7$^{\circ}C$ in the back and 31.3$^{\circ}C$ in the chest which belong to the comfort zone(31-33$^{\circ}C$). The relative humidity is 39.7%RH in the chest and 33.8%RH in the back which is slightly below the comfort zone(40-60%RH) 5. The thermal sensation belong to the comfort zone regardless of the kinds of clothes. The subjects feels a slight fatigue as times goes. As for the subjective sense of subjects the mean skin temperature as well as temperature and humidity within clothes show similar tendency. This means that they relate with each other.

• 한국지반공학회논문집
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• 제23권4호
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• pp.15-24
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• 2007

본 연구에서는 여러 지점의 온도를 동시에 측정할 수 있는 두 가지 온도 모니터링 기법을 소개하고 있다. 그 하나는 고유주소를 가지고 있는 온도센서로 구성된 온도센서 배열 케이블을 이용하는 기법이며, 다른 하나는 광섬유 센서를 이용하여 분포 온도를 측정하는 기법이다. 이 두 기법의 차이점은 다음과 같이 요약될 수 있다. 온도센서 배열 케이블은 온도센서가 위치하는 정확한 지점의 온도를 측정하게 된다. 그에 대한 온도 측정의 정밀도 및 분해능은 그 온도 센서의 성능에 따라 결정된다. 한편, 광섬유 센서는 레이저 펄스가 광섬유를 따라 보내질 때 생성되는 Raman 역산란파를 분석함으로써 온도를 측정하기 때문에 분포 개념의 온도를 측정하게 된다. 그에 대한 온도 분해능은 측정거리, 측정시간 및 온도측정 거리분해능에 따라 결정된다. 본 논문은 두 가지 온도 모니터링 시스템의 장단점을 비교함으로써 기술적이고 경제적인 측면에서 그의 응용분야를 면밀히 검토하는 데 그 목적이 있다. 이를 위해 두 기법을 이용한 다양한 실험을 실시하였다. 그 결과를 검토해 보면 온도센서 배열 케이블은 300m 범위 내의 지하수 흐름, 지열 분포 및 그라우팅 효과 검증에 적합할 것으로 판단되며 광섬유 센서는 상대적으로 긴 거리에 걸친 분포 온도에 대한 정보가 필요한 파이프 파인 감시, 터널 화재 감시 및 전력선 모니터링과 같은 분야에서 효율적으로 활용될 것이 기대된다.