• 제목/요약/키워드: Technology-to-Performance Chain

검색결과 386건 처리시간 0.024초

Muscle differentiation induced up-regulation of calcium-related gene expression in quail myoblasts

  • Park, Jeong-Woong;Lee, Jeong Hyo;Kim, Seo Woo;Han, Ji Seon;Kang, Kyung Soo;Kim, Sung-Jo;Park, Tae Sub
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제31권9호
    • /
    • pp.1507-1515
    • /
    • 2018
  • Objective: In the poultry industry, the most important economic traits are meat quality and carcass yield. Thus, many studies were conducted to investigate the regulatory pathways during muscle differentiation. To gain insight of muscle differentiation mechanism during growth period, we identified and validated calcium-related genes which were highly expressed during muscle differentiation through mRNA sequencing analysis. Methods: We conducted next-generation-sequencing (NGS) analysis of mRNA from undifferentiated QM7 cells and differentiated QM7 cells (day 1 to day 3 of differentiation periods). Subsequently, we obtained calcium related genes related to muscle differentiation process and examined the expression patterns by quantitative reverse-transcription polymerase chain reaction (qRT-PCR). Results: Through RNA sequencing analysis, we found that the transcription levels of six genes (troponin C1, slow skeletal and cardiac type [TNNC1], myosin light chain 1 [MYL1], MYL3, phospholamban [PLN], caveolin 3 [CAV3], and calsequestrin 2 [CASQ2]) particularly related to calcium regulation were gradually increased according to days of myotube differentiation. Subsequently, we validated the expression patterns of calcium-related genes in quail myoblasts. These results indicated that TNNC1, MYL1, MYL3, PLN, CAV3, CASQ2 responded to differentiation and growth performance in quail muscle. Conclusion: These results indicated that calcium regulation might play a critical role in muscle differentiation. Thus, these findings suggest that further studies would be warranted to investigate the role of calcium ion in muscle differentiation and could provide a useful biomarker for muscle differentiation and growth.

분자량 조절제의 함량에 따른 수계 아크릴 점착부여제의 합성 및 점착 특성 연구 (Study on Synthesis and Adhesion Properties of Water-based Acrylic Tackifier According to the Content of Chain Transfer Agent)

  • 백란지;정부영;김세진;허필호;천정미;천제환
    • 접착 및 계면
    • /
    • 제23권3호
    • /
    • pp.80-86
    • /
    • 2022
  • 본 연구에서는 수계형 아크릴 점착제의 성능 및 점착 물성을 향상시키기 위해 분자량 조절제인 1-dodecanethiol(n-DM)의 함량이 다른 수계 아크릴 점착부여제를 합성하였으며 수계 아크릴 점착부여제의 투입량에 따른 물성 변화 확인을 위해 수분산성 아크릴 에멀젼에 수계 아크릴 점착부여제를 10/20/30 phr로 투입하여 물성을 측정하였다. 합성된 수계 아크릴 점착부여제의 분자량 및 유리전이온도(Tg)는 n-DM의 함량이 증가함에 따라 감소하는 경향을 나타내었다. 수분산성 아크릴 에멀젼에 수계 아크릴 점착부여제를 첨가하였을 때의 점착력 및 내열 유지력은 증가하였으며 수계 아크릴 점착부여제를 10 phr 또는 20 phr로 투입하였을 때에 가장 우수한 값을 나타내었다.

다축 동기 제어 방법 기반의 산업용 고속 병렬로봇 제어 (Synchronization Error-based Control Approach for an Industrial High-speed Parallel Robot)

  • 도현민;김병인;박찬훈;경진호
    • 한국생산제조학회지
    • /
    • 제25권5호
    • /
    • pp.354-361
    • /
    • 2016
  • Parallel robots are usually used for performing pick-and-place motion to increase productivity in high-speed environments. The present study proposes a high-speed parallel robot and a control approach to improve the tracking performance for the purpose of handling a solar cell. However, the target processes are not limited to the solar cell-handling field. Therefore, a delta-type parallel manipulator is designed, and a ball joint structure is specifically proposed to increase the allowed angle that would meet the required workspace. A control algorithm considering the synchronization between multiple joints in a closed-chain mechanism is also suggested to improve the tracking performance, where the tracking and synchronization errors are simultaneously considered. In addition, a prototype machine with the proposed ball joint is implemented. A satisfactory tracking performance is achieved by applying the proposed control algorithm, with a cycle time of 0.3 s for a 0.1 kg payload.

Evolution of Automatic Ordering System in Retail Market : Analyzing Inventory Data

  • Paik, SiHyun;Frazier, DeWayne P.;Mark, Isenhoff
    • International Journal of Advanced Culture Technology
    • /
    • 제3권2호
    • /
    • pp.1-14
    • /
    • 2015
  • The purpose of this paper is to reveal two problems in the existing inventory systems in retail market, and to suggest a Two-Bin System under Automatic Ordering System considering only base-stock. Large retailers already have a sophisticated inventory system based on an automatic ordering principle. However, why does the out-of-stock (OOS) happen in large discount stores in spite of having a good inventory system? This paper suggests two systems after finding the root causes concerning the previous question. For evaluating the performance of each system, the random 200 data set in each sample group was generated from MINITAB 16 and obeyed the Poisson distribution. The existing inventory system in retail market cannot help generating OOS due to indwelling contradiction in itself. The reasons are the ordering deadline and the relationship between ordering quantity and base stock. This paper also demonstrates that these previous studies on inventory fall into the closed loop. Also the paper shows that the performance of the replenishment policy was better than traditional methods dealing with ordering quantity and base stock.

Anti-fatigue activity of dripped spent hens chicken essence in ICR mice

  • Ti Chun, Chang;Wei Cheng, Chen;Chao Wei, Huang;Liang Chuan, Lin;Jen Shinn, Lin;Fu Yuan, Cheng
    • Animal Bioscience
    • /
    • 제36권2호
    • /
    • pp.307-314
    • /
    • 2023
  • Objective: Chicken essence and branched chain amino acid (BCAA) supplementation has been recognized to significantly relieve fatigue. To obtain chicken essence with high amounts of BCAA, spent hens herein was used to prepare dripped chicken essence (SCE) and compared with commercial dripped chicken essence (CCE) for in vivo anti-fatigue effect. Methods: To determine the effect on anti-fatigue by dripped chicken essence, the exhaustive swimming was performed. Thirty-two 7-week ICR mice were divided into four groups, which included the control group (CG), CCE, SCE-1X and SCE-2X. The mice were given daily oral administration (0.012 mL/g body weight/d). The fatigue index analysis was conducted weekly. Results: The results showed that SCE had a higher BCAA level as expected, and mice treated with dripped chicken essence (CCE and SCE) could significantly improve exercise performance. The lower blood lactate level, blood urea nitrogen level and creatine phosphokinase activity were found in the supplement of SCE group compared with the CCE group, which suggested that the SCE possessed strong anti-fatigue ability. This could possibly be due to the higher content of BCAA. Conclusion: In this study, SCE promoted recovery from physical fatigue in mice and elevated endurance ability. Among them, the double dose (SCE-2X) showed the strongest anti-fatigue ability. Taken together, spent chickens could be a good source of chicken essence to improve the effect of anti-fatigue.

Research Through Empirical Analysis on SCM Efficiency Aspects of Retail Ready Packaging System

  • Jung, Sung-Tae;Kim, Ji-Hyun
    • 한국포장학회지
    • /
    • 제26권2호
    • /
    • pp.85-92
    • /
    • 2020
  • In this study, the relationship between packaging design and logistics efficiency raised in prior research was to be conducted through empirical analysis in terms of SCM efficiency. The main research contents were carried out in the pursuit of efficiency of the relevant store operation, relationship with SCM efficiency aspects, resolution of differences in recognition between manufacturers and distributors, establishment of automated systems for RRP production facilities and processes in the manufacturer's facilities, logistics costs, environment and quality safety, and promotion of RRP through the manufacturer's packaging system. As a result of the verification of SCM efficiency aspects through this study, logistics efficiency will be reduced in the case of the packaging system or delivery system, where only the operational efficiency of the store is the top priority(χ2 = 178.500, p < 0.001). This is because of the strong interaction between packaging and supply chain activities, many packaging systems affect the performance criteria of the supply chain, and the content that packaging personnel should ensure that the packaging system meets other essential requirements while meeting the primary goal of protecting the product is also a result consistent with the preceding study. An analysis of whether the RRP promotion through the manufacturer's packaging system would result in improved loading efficiency showed that there was a statistically meaningful difference at a significant level of 0.000, as χ2 = 140.133.

부틸글리시딜에테르와 이산화탄소의 부가반응에 대한 이온성 액체의 촉매 성능 고찰 (Catalytic Performance of Ionic Liquids for the Cycloaddition of Carbon Dioxide and Butyl Glycidyl Ether)

  • 박대원;주혜영;이미경
    • 한국응용과학기술학회지
    • /
    • 제25권4호
    • /
    • pp.469-476
    • /
    • 2008
  • The synthesis of cyclic carbonate from butyl glycidyl ether (BGE) and carbon dioxide was performed in the presence of three different types of ionic liquid : quarternary ammonium salt, alkyl pyridinium salt, and alkylimidazolium salt. Ionic liquids of different alkyl groups ($C_3$, $C_4$, $C_6$ and $C_8$) and anions ($Cl^-$, $Br^-$ and $I^-$) were used for the reaction which was carried out in a batch autoclave reactor at $60{\sim}120^{\circ}C$. The catalytic activity was increased with increasing alkyl chain length in the order of $C_3$ < $C_4$ < $C_6$. But the ionic liquid with longer alkyl chain length ($C_8$) decreased the conversion of BGE because it is too bulky to form an intermediate with BGE. For the counter anion of the ionic liquid catalysts, the BGE conversion decreased in the order $Cl^-$ > $Br^-$ > $I^-$.

Pretest analysis of a prestressed concrete containment 1:3.2 scale model under thermal-pressure coupling conditions

  • Qingyu Yang;Jiachuan Yan;Feng Fan
    • Nuclear Engineering and Technology
    • /
    • 제55권6호
    • /
    • pp.2069-2087
    • /
    • 2023
  • In nuclear power plant (NPP) accidents, the containment is subject to high temperatures and high internal pressures, which may further trigger serious chain accidents such as core meltdown and hydrogen explosion, resulting in a significantly higher accident level. Therefore, studying the mechanical performance of a containment under high temperature and high internal pressure is relevant to the safety of NPPs. Based on similarity principles, the 1:3.2 scale model of a prestressed concrete containment vessel (PCCV) of a NPP was designed. The loading method, which considers the thermal-pressure coupling conditions, was used. The mechanical response of the PCCV was investigated with a simultaneous increase in internal pressure and temperature, and the failure mechanism of the PCCV under thermal-pressure coupling conditions was revealed.

Performance Evaluation of Multi-Hop Communication Based on a Mobile Multi-Robot System in a Subterranean Laneway

  • Liu, Qing-Ling;Oh, Duk-Hwan
    • Journal of Information Processing Systems
    • /
    • 제8권3호
    • /
    • pp.471-482
    • /
    • 2012
  • For disaster exploration and surveillance application, this paper aims to present a novel application of a multi-robot agent based on WSN and to evaluate a multi-hop communication caused by the robotics correspondingly, which are used in the uncertain and unknown subterranean tunnel. A Primary-Scout Multi-Robot System (PS-MRS) was proposed. A chain topology in a subterranean environment was implemented using a trimmed ZigBee2006 protocol stack to build the multi-hop communication network. The ZigBee IC-CC2530 modular circuit was adapted by mounting it on the PS-MRS. A physical experiment based on the strategy of PS-MRS was used in this paper to evaluate the efficiency of multi-hop communication and to realize the delivery of data packets in an unknown and uncertain underground laboratory environment.

균형성과표(BSC)를 이용한 물류정보시스템 성과평가지표 개발 (The Development of Performance Evaluation Measures for Logistics Information Systems on the Basis of BSC)

  • 강희석;김상훈
    • 한국IT서비스학회지
    • /
    • 제12권3호
    • /
    • pp.273-287
    • /
    • 2013
  • The objective of this study is to empirically develop performance evaluation measures for LIS (logistics information systems) based upon BSC (balanced scorecard) model and determine the relative importance among four perspectives of BSC using AHP (analytic hierarchy process) methodology. Above all, forty nine probable measures for evaluating LIS performance were identified through reviewing the previous research related with SCM (supply chain management), logistics management, and information systems evaluation. And then, these probable measures were examined by means of coincidence analyses using three mutually exclusive criteria(validity of content, ease of measurement and reliability of measurement). Data for conducting the coincidence analyses were collected from LIS users and LIS development personnel. As the results of the coincidence analyses, it was found that 31 ones among 49 probable performance evaluation measures theoretically derived could be qualified for LIS performance evaluation. And AHP analysis showed that the weight of each perspective was respectively as follows : 46.8% for financial perspective, 31.3% for customer perspective, 14.8% for internal business process perspective, and 7.1% for learning and growth perspective. The academic contribution of this study is that performance evaluation measures for LIS could be systematically and empirically developed on the basis of BSC. Also, the results of this study are expected to be used as a practice guideline of evaluating and improving LIS.