• Journal of Pharmaceutical Investigation
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• v.37 no.3
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• pp.167-171
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• 2007

Itraconazole is one of the most potent antifungal agents available in the market today. However, the low bioavailability due to its poor-water solubility calls for an alternative formulation to the current oral type. A topical itra-conazole-containing formulation may be of use for several reasons including the opportunity to reduce adverse events and generate high local tissue levels, more rapid drug delivery, and lower systemic exposure. The purpose of the present study was to investigate the vehicles for topical skin delivery of itraconazole. The effect of formulations on the hairless mouse skin permeation and deposition of itraconazole was determined using Franz diffusion cells at $37^{\circ}C$. Benzyl alcohol in micro-emulsion significantly increased the solubility of itraconazole, thereby increasing the skin permeation rate. However, lipo-some formulation showed the lowest solubility and permeation rate of itraconazole. Although the solubility of itraconazole in hydrogel formulation was lower than that in microemulsion, skin permeation rate was significantly higher probably due to its adhesive property. Therefore, microemulsion-based hydrogel formulation is expected to synergistically increase the skin permeation rate and skin deposition of itraconazole.

• The Journal of the Korea Contents Association
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• v.10 no.4
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• pp.133-140
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• 2010

It is said that the highlight in the media covergence and integration within digital environment era is 'Contents'. Due to the advent of new media and various covergence and integration services, the competition between the platforms has become aggressive. As a result, it is predicted that the negotiation power of a 'Content's industry will be strengthened. In reality, the actual environmental changes in the media environment have accompanied elements of industrial crisis rather than opportunity to expand the market. The changes are especially causing sales structure distortion and proceeds deterioration in the Korean film industry. Moreover, telecommunication and broadcasting businesses are making their entrance into the film industry, through the appearance of the media covergence and integration as a backdrop. Thus, the situation that the Korean film industry is facing is closely associated with the development of the digital technology and new media environment. Eventually, weathering the crisis and pioneering the future will be possible through changes in the media environment. The purpose of this study is to show how the media covergence and integration phenomenon is occurring in the film industry. This study will also focus on what new problems are occurring as a result, and seek out the solutions that are available.

• Management & Information Systems Review
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• v.4
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• pp.29-66
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• 2000

The current economic environmental changes such as globalization, information and opening of the market is calling for or needing the more rapid change of management and/or marketing strategies of the company than they did before to survive in tile borderless international competition. Under this situation, this study focuses on the correspondence strategies of Electronic Commerce which is one of the key elements to overcome or lead the above demands through seeking the problems of the current EC acception and application specially in Chollabuk Do province. For the above purpose, this study surveys the questionary with business firms of above area and figures out what is the correlation between business form and size and EC acception and application and what is the problems on it. And than provides several counter strategies which are following based on the survey to keep this area companies from out of business and lead the above economic environmental changes. To expand the adoption and application of EC to this area, firstly, top managers of the company must recognize the necessity and importance of EC compared with traditional commerce and change their perception and attitude concerning EC positively, and than try to accept it as soon as possible. Secondly, the company need the retained earning to invest to EC and educate their managers and employees with total participation. Thirdly, local government has to improve its attention to EC as a best way or opportunity to reduce and overcome the economical gap and development its economy because EC can remove the physical time or distance and space, scale and capital limitations. Finally, government has to expand and establish information infrastructure such as technical infrastructure(communication and security technology), Functional infrastructure like standard protocol, Organizational infrastructure(interchange agreement, relative law) and social infrastructure to improve efficient electronic transaction which can Increase the company' international compatitiveness under the current economy trend.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2005.11a
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• pp.241-250
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• 2005

New product development (NPD) is defined as the transformation of a market opportunity and a set of assumptions about product technology into a product available for sale. Managers charged with project selection decisions in the NPD process, such as go/no-go choices and specific resource allocation decisions, are faced with a complicated problem. Therefore, the ability to develop new successful products has identifies as a major determinant in sustaining a firm's competitive advantage. The purpose of this study is to develop a new evaluation model for NPD project selection in the high -tech industry using support vector machines (SYM). The evaluation model is developed through two phases. In the first phase, binary (go/no-go) classification prediction model, i.e. SVM for high-tech NPD project selection is developed. In the second phase. using the predicted output value of SVM, feasibility grade is calculated for the final NPD project decision making. In this study, the feasibility grades are also divided as three level grades. We assume that the frequency of NPD project cases is symmetrically determined according to the feasibility grades and misclassification errors are partially minimized by the multiple grades. However, the horizon of grade level can be changed by firms' NPD strategy. Our proposed feasibility grade method is more reasonable in NPD decision problems by considering particularly risk factor of NPD in viewpoints of future NPD success probability. In our empirical study using Korean NPD cases, the SVM significantly outperformed ANN and logistic regression as benchmark models in hit ratio. And the feasibility grades generated from the predicted output value of SVM showed that they can offer a useful guideline for NPD project selection.

• Journal of the Korea Fashion and Costume Design Association
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• v.21 no.3
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• pp.161-172
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• 2019

This study examines the characteristics and recent changes of the Hanbok industrial cluster in Gwangju Metropolitan City, in order to understand the problems in the activation of the Hanbok industry and to seek future policies. A total 32 companies comprise the 'Small Manufacturer Specialized Support Center of Hanbok' and were surveyed with a 41 questions with questions in four categories. The Gwangju Hanbok area has been in existence for more than 40 years and was composed of small groups of one or two manufacturers. They are experiencing the same difficulties as other Hanbok clusters, such as the aging of workers, the downturn of dress culture, and changing consumption paradigms. However, since 2015, various efforts have been made in order to seek countermeasures to cope with such difficulties, particularly with the foundation of the 'Small Manufacturer Specialized Support Center of Hanbok' with the support of the Ministry of Small Venture Business. This study focuses on the alterations in the current Hanbok industry due to the IT industrialization as well as the changes in the locations of the Hanbok clusters due to the revitalization of old towns by local governments., The results providing an opportunity to appreciate the problems therein and seek the solutions. Small manufacturers of the Hanbok cluster are trying to improve their entrepreneurship, digital technology application, and knowledge in accordance with the socio-economic trends, but they have limitations to practically apply it to business, barely keeping the minimum production base. The central government and the Gwangju should reinforce and expand the support for marketing and public relations for the Hanbok to foster the designer population, to establish mutual brands, to raise brand awareness, and to promote the technological perfection of the individual businesses, to allow them to cope with the current market trends, in order for the technological development and firm settlement of the local Hanbok industrial cluster.

• International Commerce and Information Review
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• v.15 no.3
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• pp.313-332
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• 2013

Large tundra of the Russian Empire, has rich resources and science and technology, and a huge domestic market potential is rapidly changing. Based on the abundant energy resources such as oil, gas, and minerals, as foreign trade is active, the huge capital is moving. And commitment the active SOC by improving laws and regulations and changes in the structure of the Russian economy. One of them pushed the WTO since 1993, 19 years to see fruition join the WTO (World Trade Organization). As the official entry into force August 22, Russia, July 10, 2012, Congress passed the treaty after joining the WTO and of the 156th WTO member countries, was officially join. As the WTO, Russia has the world's 11th-largest economy in the steel tariffs from 30% to 15% are exported to Russia, South Korea Car TV parts from 10% to 0%, reduced from 20% to 5% Korean export companies to export to Russia, etc., is expected to become the new land of opportunity. Russia hopes the changes improve the investment environment, the service industry, manufacturing revitalization the macroeconomic sectors of the economy through the WTO, and forecast, but the consumption increased revenue due to tariff cuts, falling import prices and the real economy, and weak manufacturing base. On the one hand, the perspective of concern. In conclusion, Russia joining the WTO, and the feed to improve the fairness and transparency of the market opening, the Russian advance in Korean companies be facilitated and strong complementary cooperation, especially in manufacturing is expected. In this paper, after Russia joining the WTO, trade liberalization, and ready for a new era of economic cooperation between Korea and Russia, at the point of expanding openness to propose strategies to analyze the problems of Korean companies during the Russian advance.

• Journal of Distribution Science
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• v.15 no.3
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• pp.73-80
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• 2017

Purpose - Since Korean distribution market was opened, the domestic environment in department stores has been changed by the pattern of consumption and consumer need based on income classes. As multilateral Free Trade Agreement (FTA) accelerates opening markets, the scale of circulating capital has become bigger. Large-scale commercial facilities have developed quickly as a form of a large shopping center, thus, the matter of choice and securing market area became an important valuable in this trend. Moreover, multi-complex space has been proposed as the goal of successful business with promoting the public benefit. Research design, data, and methodology - This research studied consumer behavior using data about the life style and sales of consumers, not statistical data or survey as previous studies. This research tried to find the differentiation in complex cultural space with consumption behavior of department store. Results - As the structure of society and culture was getting diverse and complex, economic growth and development with such diversity and complexity improved consumers' quality of life. The changes of consumer life style are quite natural like human instinct. Department stores have activated retail business with the products of accumulated technology. Moreover, they have created the space of consumption and culture. Because of these social and environmental changes, department stores are being developed as Multi-functional spaces as well as sale places considering the strategies of department and the changes of consumers' purchasing behaviors. Conclusions - Urban culture complex is a landmark standing for the culture era of 21st century. It has provided an opportunity for consumers to enjoy culture, and has been an important factor to improve company images. Based on these roles and needs, expectancy effects are related with consumer preference and space preference, and the attitude toward companies. Moreover, the expectancy effects from those relationships are getting bigger and bigger. We should respect nature, a characteristic of Korean architecture, maintain visual continuity that harmonies with nature in the development of the complex space of the domestic department stores, and should take significance in the development of the complex cultural space in the direction of feeling the hierarchy of the space to obtain the visual pleasure with the artificial structure.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.17 no.5
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• pp.237-250
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• 2022

On September 28, 2020, the Korea Fair Trade Commission introduced a proposed bill entitled the "Fair Online Platform Intermediary Transactions Act." We quantify the impact of this proposed act on Naver, Korea's major digital platform. Finding a proper control unit is not an easy task in social science studies. We overcome this caveat by constructing a synthetic version of Naver using Abadie & Gardeazabal's (2003) synthetic control method. It appears that the economic cost of the proposed act is not negligible at all. Naver's opportunity loss amounted to 16.18% of its market capitalization (approximately 8.5 trillion won in comparison with its pre-regulation market capitalization). Any regulation-based approaches to resolving digital platform issues have both promises and pitfalls. The results highlight that regulatory bodies should carefully gauge the impact of such regulations, as we have seen with Naver's case.

• Information Systems Review
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• v.4 no.2
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• pp.111-131
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• 2002

Strategic information systems assist organization with the significant opportunity to gain competitive advantage in executing its business plans and realizing its business goals. The universities establish long-range plan of information systems in an effort to provide just-in-time, useful, efficient and effective information services to their members such as professors, students, and staffs when carrying out various organizational activities. The university information systems started from the primitive computer-based application, extended to the administrative and educational e-transformation, even to the virtual university concept. Through an empirical analysis and complementary case examples, the current study carefully chose three Korean universities according to their chronological importance, that have undergone the information systems planning process years from 1995 to 2001. These universities then, were compared in terms of the information technology architecture: the information architecture, infra architecture, and information management architecture. These three areas of system were cross-examined under the consideration of the evolution of information technology architecture, and its impact on the development of university e-transformation. As part of a fulfillment plan to satisfy the needs of customers of current trend, it is evident that the university e-transformation provides a stepladder to highly competitive, first class university in the market, through achieving the educational advancement, research enhancement, and administrative efficiency. The result of the study analysis indicates that, of the three architectures examined, the weakness showed in the information management architecture. Therefore it is crucial for the university staffs, managers and professors to understand the significance of the successful implementation of the information system and its maintenance. Our study certainly will act as a catalyst for the promotion of the future university e-transformation projects.

• Journal of Animal Science and Technology
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• v.47 no.1
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• pp.115-132
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• 2005

This research was conducted to make suggestions for the promotion of research activities in the field of animal resources sciences, and we evaluated the research funding trend and the present status of research funding offered by KOSEF in this field. Comparative portion of the number of research projects and grants in this field to other fields has a tendency to be decreased year by year except recent few years. Researchers in this field have received more research funding from the group-based program than from the individual-based program. Also, they have received less money(per project) than did researchers in the fields of general agricultural sciences and other science and technology. Researchers in this field ranges from 43 to 51 years of age and showed 48 years of average age. It was found that researchers who has been funded in the field of animal resources sciences have showed tendency of publication of more articles to SCI journals in recent 5 years. The strong points of the animal resources of agricultural sciences field in South Korea include: lots of researchers, the establishment of research infra-structure, the excellence in research competitiveness and technology level. However, its weaknesses are: a lack of leadership in relevant societies and institutes, a predicted shortfall of researchers in the next generation and insufficient research productivity. The opportunities include: increasing the importance of the biotechnology industry, activating international cooperation researches and exploring the multitude of possible research areas to be studied. However, some concerns still exist, such as threats from developed countries for the government to open the agricultural market, the reduction of the number of full-time farms and intensification of needs for economic and social effects. The diverse actions and systems based upon the strongpoint, weakness, opportunity and threats above-mentioned are required to encourage research activities in the field of animal resources of agricultural sciences in Korea In addition, researchers in this fields would make an effort to keep pace with international society as well as domestic demands.