• Title/Summary/Keyword: Technetium-99m

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$^{99m}Technetium-methylene$ Diphosphonate의 전신 골격주사술을 이용한 관절염의 핵의학적 진단 (Scintigraphic Detection of Adjuvant-induced Arthritis in Rats Using $^{99m}Technetium-methylene$ Diphosphonate)

  • 강성수;궁성수;배춘식;최석화
    • 한국임상수의학회지
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    • 제18권2호
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    • pp.133-138
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    • 2001
  • 본 연구는 랫드에서 Freund's complete adjuvant를 랫드의 후지에 투여하여 인의적으로 유발된 관절염을 진단하기 위한 방법으로 $^{99m}Technetium-MDP (^{99m}Tc_MDP$)을 이용한 골 스캔의 임상적 의의를 찾고자 하였다. 성숙 Sprague-Dawley 암컷 랫드를 대조군과 실험군으로 분리하고, 골의 스캔은 0.05mCi의 $^{99m}Tc_MDP$를 정맥 주사하여 3시간 후에 전신 영상을 얻었다. 골의 스캔과 방사선학적 평가를 비교한 겨과 관절염 유발 7일 후부터 관절염의 병변이 관찰되었지만, 방사선학적 소견에서는 14일 후부터 병변이 관찰되었다. 골의 스캔에서 관절염 유발 7일 후에 유의적으로 골의 이상적 섭취 증각가 관찰되었고(p<0.05), 21일 후에는 전지와 후지의 모든 부위에서 골의 이상적 섭취 증가가 관찰되었지만, 방사선학적 소견에서는 후지에서만 병변 부위가 관찰되었다. 이상의 결과에서 $^{99m}Tc_MDP$을 이용한 골의 스캔은 류마티스 관절염을 임상적으로 진단하는데 방사선학적 진단보다 효과적인 방법임을 알 수가 있었고, 골의 스캔은 류마티스 관절염을 초기에 진단하는데 유효한 진단방법임을 확인하였다.

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Thyroid imaging in 53 cats with hyperthyroidism using technetium-99m as pertechnetate

  • Lee, Young-won
    • 대한수의학회지
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    • 제39권2호
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    • pp.394-397
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    • 1999
  • Thyroid imaging was performed in 53 hyperthyroid cats with technetium-99m as pertechnetate($^{99m}TcO_{4}$). Increased radionuclide accumulation was found in all cats. Thirty-four cats had bilateral enlargements of the thyroid glands and 14 cats had unilateral enlargements. Five cats had multi-focal accumulation of $^{99m}TcO_{4}$ in the ventral neck or mediastinum. Conclusively, nuclear thyroid image is useful method in diagnosis of feline hyperthyroidism.

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$^{99m}Technetium$ Methylene Diphosphonate Bone Scan에서 원발병소가 조영된 신경아세포종 2예의 치험 (Primary Neuroblastoma Uptake in $^{99m}Technetium$ Methylene Diphosphonate Bone Scan (2 Cases))

  • 권태원;정풍만;조석신;고영혜
    • 대한핵의학회지
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    • 제21권2호
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    • pp.213-219
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    • 1987
  • Although the exact mechanism is not clearly understood yet, there were examples of the uptake of radiopharmaceuticals to the soft tissue lesions with $^{99m}Technetium$ methylene diphosphonate bone scan. Recently, we experienced two cases of neuroblastoma of which primary sites were imaged with $^{99m}Tc-MDP$ bone scan preoperatively and could make the diagnosis. So, we report here that $^{99m}Tc-MDP$ bone scan is the reasonable method not only to find out the bone metastasis, but also to diagnose the neuroblastoma preoperatively.

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Technetium-99m 골주사를 이용한 하악골의 자가골 및 동종골 이식의 평가에 대한 실험적 연구 (TECHNETIUM-99m BONE SCAN FOR EVALUATING AUTOLOGOUS ILIAC BONE GRAFT AND FREEZE-DRIED BONE ALLOGRAFT IN DOG'S MANDIBLE)

  • 진성박;김수경
    • 대한치과의사협회지
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    • 제22권1호통권176호
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    • pp.37-48
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    • 1984
  • Clinical assessment of bone-graft healing in the maxillofacial region is generally limited to clinical evaluation, radiographs, and biopsy. Sequential interpretation of osseous repair, more sensitive than with conventional radiography is possible with a non-invasive, non-destructive radionuclide method. Technetium-99m radionuclide bone scan was used in the evaluation of the progress of osteogenic activity in autologous iliac bone graft and freeze-dried bone allograft of dog's mandible. Bone scan was performed at 1wk, 2wk, 4wk, 6wk, and 8wk after grafting. In autologous graft the activity ratio for the graft bone remained greater than that of the host since 2자 after grafting; however, in lyophilized allograft the activity ratio for graft bone was greater than that of the host at 6자 after grafting.

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$^{99m}TC$-Pertechnetate에 의한 출혈성 Meckel 게실의 진단 2예 (Diagnosis of a Bleeding Meckel's Diverticulum Using $^{99m}$Technetium Pertechnetate Scanning - A case report -)

  • 허영수;김재황;권굉보
    • Journal of Yeungnam Medical Science
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    • 제4권1호
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    • pp.129-132
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    • 1987
  • 본 영남대학교 외과학교실 Meckel게실로 인한 출혈을 주소로 입원할 두 경의 환자에서 수술전 $^{99m}TC$-perechnetate의 이용에 의한 성공적 진단을 하고 수술로써 이를 확인 치험하였기에 이에 대한 증례보고와 함께 문헌고찰을 하였다.

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악성 흉선종에서 관찰된 Tc-99m MIBI와 Tl-201의 섭취 (Tc-99m MIBI and Tl-201 Uptake in a Thymic Carcinoma)

  • 현인영
    • 대한핵의학회지
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    • 제37권4호
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    • pp.260-261
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    • 2003
  • Tc-99m methoxyisobutylisonitrile (MIBI) and Tl-201/technetium subtraction scintigraphy have been used for localization of abnormal parathyroid gland. The uptake mechanism of tracers has been postulated to be increased cellular density and vascularity, or dependent on the presence of mitochondria-rich cells. However, the uptake of these tracers was not specific for abnormal parathyroid gland. The author report a case of thymic carcinoma that would have been mistaken for carcinoma of parathyroid because of Tc-99m MIBI and Tl-201 uptake.

$^{99m}Technetium$-가열처리 적혈구에 의한 비장스캔 ([ $^{99m}Technetium-Heat$ ] Damaged Erythrocyte Spleen Scan)

  • 최창운;박석건;정준기;이명철;조보연;고창순;정순일
    • 대한핵의학회지
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    • 제20권1호
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    • pp.39-43
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    • 1986
  • [ $^{99m}Technetium-Heat$ ] damaged erythrocyte were used as spleen scanning agents in 12 patients from July, 1985 to April, 1986. We used this scan to evaluate situs inversus, asplenia, accessory spleen, hypersplenism, splenic infarction, tumor staging and evaluation of therapy, especially when the $^{99m}Tc-tin$ colloid scans were not definite for diagnosis. The techniques applied to these scans were in vivo/in vitro-labeling method and heating-method to damage the erythrocytes. Liver-to-spleen uptake ratios were increased upto 100 : 1 and interference from the left lobe of the liver was eliminated. These scans were helpful to evaluate the spleen.

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