• Title/Summary/Keyword: Tear staining syndrome

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Trimethoprim-Sulfamethoxazole for the Treatment of Tear Staining Syndrome in Dogs (개의 눈물착색증후군(Tear Staining Syndrome) 치료를 위한 Trimethoprim-Sulfamethoxazole)

  • Cho, Youn-Sook;Kim, Joon-Young;Jeong, Soon-Wuk
    • Journal of Veterinary Clinics
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    • v.25 no.2
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    • pp.115-118
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    • 2008
  • 22 dogs (31 eyes) that had treated with trimethoprim-sulfamethoxazole for tear staining syndrome at Snoopy Pet Clinic from October 2000 to September 2002 were reviewed. Of the 22 dogs, 12 were female and 10 male. Their mean (${\pm}$ SD) age was 3.5 (${\pm}\;1.3$) years. The breeds of the dogs consisted of Maltese (8 dogs), Shih tzu (6 dogs), Poodle (5 dogs), Yorkshire terrier (2 dogs), and Mixed (1 dog). The dogs received 30 mg/kg trimethoprim-sulfamethoxazole perorally twice daily for two to six weeks. 26 (19 dogs) of the 31 eyes (22 dogs) recovered completely and did not show relapse at $26{\sim}30$ weeks after treatment. Any complications did not observed. Five eyes of three dogs were not cured. Two eyes (one dogs) of them had not response to medicament and three eyes (two dogs) recurrence but the clinical signs decreased. It was considered that the trimethoprim-sulfamethoxazole was effective for the treatment in dogs with tear staining syndrome.

Ocular Bacteria and Concentration of Lactoferrin in Poodle Dogs with Tear Staining Syndrome (Tear Staining Syndrome을 보이는 Poodle에 있어서 내안각의 세균총 및 눈물의 Lactoferrin 함량)

  • Seo Kang-moon;Park Yong-ho;Nam Tchi-chou
    • Journal of Veterinary Clinics
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    • v.12 no.1
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    • pp.829-837
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    • 1995
  • This study was performed to evaluate the effects of ocular bacteria and tear lactoferrin on the Tear Staining Syndrome(TSS) in poodle dogs. Staphylococcus, Klebsiella, Micrococcus and Pseudomonas were the most Prevalent microorganisms isolated in normal eyes of poodle dogs, whereas the predominant isolates in the poodle dogs with TSS were Micrococcus, Staptococcus and Staphylococcus. There were no significant differences between the normal and tear-stained poodle dogs in the quantity of tear lactoferrin. In vitro hair staining experiment, bacteria isolated from the eyes with TSS and lactoferrin didn't stain hair. The results have shown that either ocular bacteria or tear lactoferrins were not related to the TSS.

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Tear formation, the patency and the angle of bend of nasolacrimal duct in poodle dogs with tear staining syndrome (Tesr staining syndrome이 있는 poodle에서 눈물생산, 비루관 개통성 및 굴곡도)

  • Seo, Kang-moon;Nam, Tchi-chou
    • Korean Journal of Veterinary Research
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    • v.35 no.2
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    • pp.383-390
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    • 1995
  • This study was performed to investigate the characteristics of tear staining syndrome in poodle dogs. Schirmer tear test, fluorescein dye test and measurement of the angle of bend between vertical and horizontal bony nasolacrimal duct were conducted in both poodles and German shepherd dogs. There were no significant differences between normal and tear-stained poodles in tear formation determined by Schimer tear test. However, there was significantly higher tear production in German shepherds than that in normal poodles(p<0.05). In the fluorescein dye test for the measurement of tear excretion, the dye was observed within $14.5{\pm}6.5$ minutes after dropping of the dye in normal poodles, but was not observed even over 30 minutes in tear-stained poodles. German shepherds had rather rapid passage time($0.4{\pm}0.3$ minutes) than poodles in the dye excretion. In the measurement of the angle of bend between vertical and horizontal bony nasolacrimal duct through dacryocystorhinography, there were no significant differences between normal tear-stained poodles with showing $85.0{\pm}6.8^{\circ}$ and $89.8{\pm}6.5^{\circ}$, respectively. However, obtuse angle of bend($106.8{\pm}4.7^{\circ}$) was shown in German shepherds. These results have ascertained that tear staining syndrome of poodle dogs was not related to tear production but to the rate of tear excretion.

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Effects of Cryosurgery of the Third Eyelid Gland on Tear Production and Histological Changes in Dogs (개에서 제3안검선 냉동수술이 눈물생산량 및 조직학적 변화에 미치는 영향)

  • 서강문;공인주
    • Journal of Veterinary Clinics
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    • v.17 no.1
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    • pp.121-128
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    • 2000
  • The effects of cryosurgery on tear production and histological changes of the third eyelid were studied in dogs. Clinically normal 12 mixed breeds weighing 2∼6 kg were divided into three groups and treated as follows; 45 seconds double freeze-thaw treated group, 60 seconds double freeze-thaw treated group and 90 seconds double freeze-thaw treated group. The significant decrease of the tear production after cryosurgery was shown in all groups throughout the observed periods(p<0.05). However, there was no difference among groups. The main complications after cryosurgery were chemosis and conjunctival injection. Other complications such as eyelid edema, eyelid depigmentation and keratitis were more preominent in group III compared to those of groups I and II. On histopathological examination, chronic inflammatory changes and regeneration of the third eyelid glands were noted in group I and predominated loss of the third eyelid glands and necrosis of hyaline cartilage were observed in group III However, such changes were less appeared in group II. The results of this study suggested that double freeze-thaw cryosurgery for 60 seconds on the third eyelid glands would be the most effective method for treating tear staining syndrome.

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