• Radiation Oncology Journal
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• v.35 no.1
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• pp.16-24
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• 2017

Locally advanced non-small cell lung cancer (LA-NSCLC) is composed of heterogeneous subgroups that require a multidisciplinary team approach in order to ensure optimal therapy for each patient. Since 2010, the National Comprehensive Cancer Network has recommended chemoradiation therapy (CRT) for bulky mediastinal disease and surgical combination for those patients with single-station N2 involvement who respond to neoadjuvant therapy. According to lung cancer tumor boards, thoracic surgeons make a decision on the resectability of the tumor, if it is determined to be unresectable, concurrent CRT (CCRT) is considered the next choice. However, the survival benefit of CCRT over sequential CRT or radiotherapy alone carries the risk of additional toxicity. Considering severe adverse events that may lead to death, fit patients who are able to tolerate CCRT must be identified by multidisciplinary tumor board. Decelerated approaches, such as sequential CRT or high-dose radiation alone may be a valuable alternative for patients who are not eligible for CCRT. As a new treatment strategy, investigators are interested in the application of the innovative radiation techniques, trimodality therapy combining surgery after high-dose definitive CCRT, and the combination of radiation with targeted or immunotherapy agents. The updated results and on-going studies are thoroughly reviewed in this article.

• The Journal of Information Systems
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• v.25 no.3
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• pp.175-196
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• 2016

Purpose The development of new products in automobile parts industry plays an important role. Nowadays, automobile industry is one of the most important industries in the world, because automobile industry includes the industries of steel, machinery, electronic, etc. As a result, automobile industry embodies a country's level of development and competitiveness. The purpose of this study is to analyze the relationship between team characteristics such as communication, familiarity, and contiguity, and team performance through TMS in the process of new products development in automobile parts industry. Design/Methodology/Approach Based on real phenomenon of Korean automobile parts industry, this study tried to figure out the influence of TMS between team members for new product development on team performance. Thus, this study adopts communication, familiarity and contiguity as antecedents, and TMS with specialty, credibility and coordination as a mediating variable, and adopts team performance as a dependent variable. The data of questionnaire were collected from team managers who belong to new product development team in automobile parts firms. 171 questionnaires as data unit of group level from 80 Korean automobile parts firms were collected using face-to-face interview methods. Findings This study proved empirically that the relationship between antecedents and TMS has a positive influence, and TMS also has a positive influence on team performance. This study provides the managers an insight that automobile parts companies should pay more attention to set up TMS in order to improve higher performance between their team members for new product development of automobile parts.

• Toxicological Research
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• v.25 no.2
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• pp.85-92
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• 2009

4,4'-Methylenedianiline (MDA) is an aromatic amine that is widely used in the industrial synthetic process. Genotoxic MDA forms DNA adducts in the liver and is known to induce liver damage in human and rats. To elucidate the molecular mechanisms associated with MDA-induced hepatotoxicity, we have identified genes differentially expressed by microarray approach. BALB/c male mice were treated once daily with MDA (20 mg/kg) up to 7 days via intraperitoneal injection (i.p.) and hepatic damages were revealed by histopathological observation and elevation of serum marker enzymes such as AST, ALT, ALP, cholesterol, DBIL, and TBIL. Microarray analysis showed that 952 genes were differentially expressed in the liver of MDA-treated mice and their biological functions and canonical pathways were further analyzed using Ingenuity Pathways Analysis (IPA). Toxicological functional analysis showed that genes related to hepatotoxicity such hyperplasia/hyperproliferation (Timp1), necrosis/cell death (Cd14, Mt1f, Timp1, and Pmaip1), hemorrhaging (Mt1f), cholestasis (Akr1c3, Hpx, and Slc10a2), and inflammation (Cd14 and Hpx) were differentially expressed in MDA-treated group. This gene expression profiling should be useful for elucidating the genetic events associated with aromatic amine-induced hepatotoxicity and for discovering the potential biomarkers for hepatotoxicity.

• Journal of the Korean Society of Safety
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• v.12 no.3
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• pp.67-75
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• 1997

This paper presents a study on the application of Asynchronous Team(A-Team) theory for QVC(Reactive power control) and security assessment in a power system. Reactive power control problem is the one of optimally establishing voltage level given reactive power sources, which is very important problem to supply the demand without interruption and needs methods to alleviate a bus voltage limit violation more quickly. It can be formulated as a mixed-integer linear programming(MILP) problem without deteriorating of solution accuracy to a certain extent. The security assessment is to estimate the relative robustness of the system and deterministic approach based on AC load flow calculations is adopted to assess it, especially voltage security. A distance measure, as a measurement for voltage security, is introduced. In order to analyze the above two problem, reactive power control and static security assessment, In an integrated fashion, a new organizational structure, called an A-team, is adopted. An A-team is well-suited to the development of computer-based, multi-agent systems for operation of large-scaled power systems. In order to verify the usefulness of the suggested scheme herein, modified IEEE 30 bus system is employed as a sample system. The results of a case study are also presented.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.53-53
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• 2010

The development of synthetic pathway to produce a highly yield nanoparticles is an important aspect of industrial technology. Herein, we report a simple, rapid approach to synthesize organic-soluble Cu and Ag nanoparticles in colloidal method for the application in a conductive pattern using inkjet printing. The silver nanoparticles have been synthesized in highly concentrated organic phase. The Cu nanoparticles have been synthesized by the reducing of the copper oxide materials using acid molecules in high concentrated organic phase. Their sintering and electric conductivity properties were investigated by melting process between $200^{\circ}C$ and $250^{\circ}C$ for application to printed electronics.

• Asia pacific journal of information systems
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• v.20 no.1
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• pp.101-125
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• 2010

This paper uses the status inconsistency theory to identify factors related to team members' (dis)satisfaction with the composition of virtual IT project teams in order to predict their turnover intentions. Our approach is based on the premise that virtual teams, although increasingly popular among global organizations, create an environment replete with cultural and functional diversity. Yet, a paradox exists: increasing diversity in virtual teams maximizes the creation and use of organizational knowledge while simultaneously increasing dissatisfaction and turnover. This is a critical issue in the formation and management of virtual teams. Therefore, we investigate how team members' perceptions of differences among themselves (i.e. foreignness) impact the stability of team membership, leading to what we describe as a 'liability of foreignness.' Findings indicate that a member's perception of foreignness has a detrimental effect on satisfaction with his or her team members while satisfaction is likely to decrease turnover intention. This may be an implication that managers need to maintain a balance in order to discourage member turnover and the loss of key players.

• Korean Journal of Cleft Lip And Palate
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• v.8 no.2
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• pp.95-105
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• 2005

Cleft lip and palate is a congenital deformity which needs a professional and consistent management from the birth and along with the physical growth of patients. The patients with cleft lip and palate can have general speech problems with resonance disorders, voice disorders and articulation disorders after the successful primary surgical management and the physical growth. Speech problems of Cleft lip and palate are characterized hypernasality, nasal air emission, increased nasal air flow, and aberrant speech marks which decrease intelligibility. These speech problems of cleft lip and palate can be treated with the secondary surgical procedure, the application of temporary prosthesis and the effective and well-timed speech therapy. The speech and language problems of cleft lip and palate, the general procedures and schedules of the speech assessment and therapy based on the multidisciplinary approach are introduced for the patients with cleft lip and palate, their family and the other members of the cleft palate treatment team.

• Journal of the Ergonomics Society of Korea
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• v.27 no.1
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• pp.9-19
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• 2008

Work-related musculoskeletal hazards in a paper-making industry were examined to explore ergonomic interventions in a participatory approach for mitigating the hazards. Manual tasks occurred in this paper-making industry were quite different with ordinary assembly industry where individual workers perform certain specified tasks repetitively. Workers used to perform varieties of team-based irregular manual tasks to interact with the facilities. Among 96 manual jobs investigated, 44 potential hazardous jobs were screened during basic investigation phase and finally 16 hazardous jobs were identified by the detailed analysis phase. The major hazardous factors were awkward postures and excessive weights. Possible ways of intervention were developed, reviewed and proposed by an ergonomics team comprised of staffs and engineers from various departments and ergonomics specialist from outside the company. The proposed intervention ideas were evaluated and modified by the workers and union representatives in terms of usability and comfort. Implemented interventions including mechanization, automation, and improvement of tools and equipments provided fairly promising results.

• Journal of Chest Surgery
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• v.54 no.4
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• pp.235-238
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• 2021

The establishment of minimally invasive surgery is a complex and difficult task. Video-assisted thoracic surgery (VATS) refers to a minimally invasive surgical technique that represents a less invasive approach to thoracic surgery using thoracoscopy. For lung cancer or esophageal cancer surgery, planning and establishing a team for minimally invasive surgery for the first time is not a simple task. Technical advances in surgical devices and the enhanced skill of surgeons are cornerstones of the development of minimally invasive surgery. Here, we review the meaning of minimally invasive thoracic surgery and discuss how to establish a team approach for VATS procedures.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.3
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• pp.216-227
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• 2020

The purpose of this paper is to identify a relative importance and priority of the factors of Competencies of project team member. It aims to present the differential competency factors from a differentiated perspective by applying the Leadership Development Questionnaire, which is the competency dimension required for manager, to team member. (1) Background: The diverse needs of customers and companies, and the uncertainty, complexity, ambiguity, and volatility of the environment surrounding the company in the era of the Fourth Industrial Revolution threaten the survival of company. In this respect, companies should implement the project management approach and strive to increase the capabilities of each team member. (2) Methods: AHP method was used to prioritize which factors were considered more importance level and the gap of relative importance level between project manager group and team members group. (3) Results: In the analysis of the relative importance of the upper class, weights were derived in the order of managerial competence, intellectual competence, and emotional competence. The sub-factor that respondents prioritize was communication as the 1st priority, and it was analyzed in the order of strategic perspective, achieving, critical analysis and judgement, and vision and imagination. There were some differences in the ranking of the relative importance of achieving and vision and imagination attributes between the PM group and TM group, it was analyzed that there was no significant difference overall. (4) Implications: The results of this study confirmed the recognition that team members are required to have the same competencies as the project manager. And based on the priorities of the competencies required of team members, companies are expected to cultivate professional and competent team members, and expand the roles and authority of team members so that they can actively carry out projects.