• International Journal of Computer Science & Network Security
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• v.22 no.7
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• pp.75-84
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• 2022

The efficiency of the regional fiscal policy implementation is based on the achievement of target criteria in the formation and distribution of own financial resources of local budgets, reducing their deficit and reducing dependence on transfers. It is also relevant to compare the development of financial autonomy of regions in the course of decentralisation of fiscal relations. The study consists in the cluster analysis of the effectiveness of fiscal policy implementation in the context of 24 regions and the capital city of Kyiv (except for temporarily occupied territories) under conditions of fiscal decentralisation. Clustering of the regions of Ukraine by 18 indicators of fiscal policy implementation efficiency was carried out using Ward's minimum variance method and k-means clustering algorithm. As a result, the regions of Ukraine are grouped into 5 homogeneous clusters. For each cluster measures were developed to increase own revenues and minimize dependence on official transfers to increase the level of financial autonomy of the regions. It has been proved that clustering algorithms are an effective tool in assessing the effectiveness of fiscal policy implementation at the regional level and stimulating further expansion of financial decentralisation of regions.

• Molecules and Cells
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• v.45 no.7
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• pp.444-453
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• 2022

Multivalent macromolecular interactions underlie dynamic regulation of diverse biological processes in ever-changing cellular states. These interactions often involve binding of multiple proteins to a linear lattice including intrinsically disordered proteins and the chromosomal DNA with many repeating recognition motifs. Quantitative understanding of such multivalent interactions on a linear lattice is crucial for exploring their unique regulatory potentials in the cellular processes. In this review, the distinctive molecular features of the linear lattice system are first discussed with a particular focus on the overlapping nature of potential protein binding sites within a lattice. Then, we introduce two general quantitative frameworks, combinatorial and conditional probability models, dealing with the overlap problem and relating the binding parameters to the experimentally measurable properties of the linear lattice-protein interactions. To this end, we present two specific examples where the quantitative models have been applied and further extended to provide biological insights into specific cellular processes. In the first case, the conditional probability model was extended to highlight the significant impact of nonspecific binding of transcription factors to the chromosomal DNA on gene-specific transcriptional activities. The second case presents the recently developed combinatorial models to unravel the complex organization of target protein binding sites within an intrinsically disordered region (IDR) of a nucleoporin. In particular, these models have suggested a unique function of IDRs as a molecular switch coupling distinct cellular processes. The quantitative models reviewed here are envisioned to further advance for dissection and functional studies of more complex systems including phase-separated biomolecular condensates.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.8
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• pp.2648-2665
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• 2022

Device-to-device (D2D) multicast has become a promising technology to provide specific services within a small geographical region with a high data rate, low delay and low energy consumption. However, D2D multicast communications are allowed to reuse the same channels with cellular uplinks and result in mutual interference in a cell. In this paper, an intelligent channel assignment algorithm is designed in D2D underlaid cellular networks with the target of maximizing network throughput. We first model the channel assignment problem to be a throughput maximizing problem which is NP-hard. To solve the problem in a feasible way, a novel channel assignment algorithm is proposed. The key idea is to find the appropriate cellular communications and D2D multicast groups to share a channel without causing critical interference, i.e., finding a channel for a D2D multicast group which generates the least interference to network based on current channel assignment status. In order to show the efficacy and effectiveness of our proposed algorithm, a novel search algorithm is proposed to find the near-optimal solution as the baseline for comparisons. Simulation results show that the proposed algorithm improves the network throughput.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.25 no.4
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• pp.67-89
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• 2022

This study aimed to elucidate the distribution of vascular plants on the Deok mountain in Ganghwa-gun, Korea. The results of 10 field surveys from March to October of 2019 identified 532 taxa in total, representing 482 species, 9 subspecies, 39 varieties, 1 form, and 1 hybrid in 318 genera and 105 families. The plant formation of Deok mountain is the deciduous broad-leaved and conifer mixed forest, which is the common one in the middle region of the Korean Peninsula. Among them, 301 taxa were newly recorded in this study, 7 taxa were endemic plants to Korea, 3 taxa were red list plants. The floristic target plants amounted to 41 taxa, specifically 1 taxon of grade V, 2 taxa of grade IV, 7 taxa of grade III, 9 taxa of grade II, and 22 taxa of grade I. Alien plants were recorded a total of 73 taxa with a naturalized index of 13.7%, the urbanization index was calculated to be 11.8% and 4 taxa were ecosystem disturbance plants.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.7 no.2
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• pp.69-77
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• 2021

No-carrier-added holmium-166 (n.c.a ¹⁶⁶Ho) separation is performed based on the results of separation conditions using stable isotopes dysprosium (Dy) and holmium (Ho) to minimize radioactive waste from separation optimization procedures. Successful separation of two adjacent lanthanides was achieved by cation-exchange chromatography using a sulfonated resin in the H+ form (BP-800) and α-hydroxyisobutyric acid (α-HIBA) as eluent. For the identification process after separation of stable isotopes, the use of chromogenic reagents alternatively enables on-line detection because the lanthanides are hardly absorb light in the UV-vis region or exhibit radioactivity. Four different chromogenic reagents were pre-tested to evaluate suitable coloring reagents, of which 4-(2-Pyridylazo)resorcinol is the most recommendable considering the sensitivity and specificity for lanthanides. Lanthanide radioisotopes (RI) were monitored for separation with an RI detector using a lab-made separation LC system. Under the proper separation conditions, the n.c.a ¹⁶⁶Ho was effectively obtained from a large amount of 100 mg dysprosium target within 2 hrs.

• Archives of Plastic Surgery
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• v.50 no.4
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• pp.384-388
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• 2023

Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant disease characterized by multisystemic developmental defects caused by pathogenic variants such as patched-1 (PTCH1) gene variants and/or SUFU gene variants. The presence of either two main criteria or one major and two minor criteria are required for the diagnosis of Gorlin-Goltz syndrome. Recently, a major criterion for molecular confirmation has also been proposed. In this article, we report the case of an 80-year-old male who was admitted at our department for multiple brown-to-black papules and plaques on the entire body. He was diagnosed with Gorlin-Goltz syndrome with clinical, radiologic, and pathologic findings. While the diagnosis was made based on the clinical findings in general, confirmation of the genetic variants makes an ideal diagnosis and suggests a new treatment method for target therapy. We requested a genetic test of PTCH1 to ideally identify the molecular confirmation in the hedgehog signaling pathway. However, no pathogenic variants were found in the coding region of PTCH1, and no molecular confirmation was achieved.

• Nuclear Engineering and Technology
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• v.54 no.11
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• pp.4338-4347
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• 2022

The CUPID code was developed and is continuously updated in KAERI. Verification and validation (V&V) is mainly done for light water reactors (LWRs). This paper describes a benchmarking of the detailed mesh level compared with sub-channel level for application to pressurized heavy water reactors (PHWRs), even though component scale comparison for the PHWR moderator system was done once before. We completed a sub-channel level comparison between the CUPID code and the ASSERT code and a CUPID code analysis. Because the ASSERT code has already been validated with numerous experiments, benchmarking with the ASSERT code will offer us more trust on the CUPID code. The target channel has high power and thus high pressure deformation. The high power channel tends to have a high possibility of critical heat flux (CHF), because a high void fraction and quality in channel exit region appear. In this research, after determining the reference grid and T/H model, we compared the sub-channel level results of the CUPID code with those of the ASSERT code.

• Journal of the Korean Institute of Rural Architecture
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• v.25 no.2
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• pp.9-16
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• 2023

This study attempted to analyze the aspect of seeking a characteristic regeneration of low-rise residential areas through the Urban Regeneration New Deal Project in Seohak-dong Art Village in Jeonju, while the urban regeneration new deal projects are being carried out in various regions, nationwide. Time-series changes in aerial photographs in the study area, age, number of floors, and uses of buildings were examined. The main street structure, lots, and changes in buildings were reviewed, and through this, spatial zones that could extract the unique characteristics of the target area were classified. The characteristics of each area was linked to the proposal of an appropriate regeneration plan through the analysis. This study is meaningful in showing a case of characteristics of low-rise residential areas regeneration plan suitable for the specific region while the number of old low-rise residential areas is increasing.

• Journal of Ceramic Processing Research
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• v.13 no.spc2
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• pp.407-410
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• 2012

The properties of Al-doped ZnO (AZO) films were investigated as a function of H2/(Ar + H2) gas ratio using an AZO (2 wt% Al2O3) ceramic target in a radio frequency (RF) magnetron sputtering system. The deposition process was done at 200 ℃ and in 2 × 10-2Torr working pressure and with various ratios of H2/(Ar + H2) gas. During the AZO film deposition process, partial H2 gas affected the AZO film characteristics. The electron resistivity (~ 9.21 × 10-4 Ωcm) was lowest and mobility (~17.8 ㎠/Vs) was highest in AZO films when the H2/(Ar + H2) gas ratio was 2.5%. When the H2/(Ar + H2) gas ratio was increased above 2.5%, the electron resistivity increased and mobility decreased with increasing H2/(Ar + H2) gas ratio in AZO films. The carrier concentration increased with increasing H2/(Ar + H2) gas ratio from 0% to 7.5%. This phenomenon was explained by reaction of hydrogen and oxygen and additional formation of oxygen vacancy. The average optical transmission in the visible light wavelength region over 90% and an orientation of the deposition was [002] orientation for AZO films grown with all H2/(Ar + H2) gas ratios.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.1
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• pp.54.2-54.2
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• 2021

Galaxy clusters are the largest structures in the universe located at the top of the cosmological hierarchical model, so the evolution of the universe can be understood by studying clusters of galaxies. Therefore, finding a larger number of galaxy clusters plays an important role in exploring how the universe evolves. A large number of catalogs for galaxy clusters in the northern sky have been published; however, there are few catalogs in the southern sky due to the lack of wide sky survey data. KMTNet Synoptic Survey of Southern Sky(KS4) project, which observes a wide area of the southern sky about 7000 deg² with KMTNet telescopes for two years, is in progress under the SNU Astronomy Research Center. We use the KS4 multi-wavelength optical data and measure photometric redshifts of galaxies for finding galaxy clusters at redshift z<1. Currently, the KS4 project has observed approximately 33% of the target region, and a pipeline that measures photometric redshifts of galaxies has been created. When the project is completed, we expect to find more than a hundred thousand galaxy clusters, and this will improve the study of galaxy clusters in the southern sky.