• The Journal of Asian Finance, Economics and Business
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• v.7 no.9
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• pp.593-602
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• 2020

The purpose of this study is to examine and analyze the effect of human capital supply chain on the firm performance mediated by innovation culture and innovation process on small- and medium-sized construction enterprises (SMEs) in Indonesia. A survey has been distributed to all construction SMEs that have direct involvement in construction work (contractors and subcontractors). The construction SMEs including medium- and small-scale construction services in three Provinces, namely, the special region of Yogyakarta, East Java, and Central Java. Through purposive sampling technique, primary data is collected by giving a questionnaire to the owner/manager of construction SMEs. The target sample in this study was 200 respondents who have been operating for a minimum of two years. 154 valid questionnaires could be processed. Data analysis uses structural equation modeling with AMOS 24. The results of the study conclude that there is a positive effect on human capital supply chain on firm performance mediated by innovation culture and innovation process, while innovation culture does not affect firm performance. In sum, the innovation culture mediates the relationship between human capital supply chain and firm performance, and the innovation process mediates the relationship between human capital supply chain and firm performance.

• BMB Reports
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• v.48 no.7
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• pp.371-372
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• 2015

MicroRNAs (miRNAs) can regulate the expression of genes that are involved in multiple cellular pathways. However, their targets and mechanism of action associated with the autophagy pathway are not fully investigated yet. EWSR1 (EWS RNA-Binding Protein 1/Ewing Sarcoma Break Point Region 1) gene encodes a RNA/DNA binding protein that is ubiquitously expressed and plays roles in numerous cellular processes. Recently, our group has shown that EWSR1 deficiency leads to developmental failure and accelerated senescence via processing of miRNAs, but its role in the regulation of autophagy remains elusive. In this context, we further investigated and found that EWSR1 deficiency triggers the activation of the DROSHA-mediated microprocessor complex and increases the levels of miR125a and miR351, which directly target Uvrag. Interestingly, the miR125a- and miR351-targeted reduction of Uvrag led to the inhibition of autophagy in both ewsr1 knockout (KO) MEFs and ewsr1 KO mice. In summary, our study demonstrates that EWSR1 is associated with the posttranscriptional regulation of Uvrag via miRNA processing. The regulation of autophagy pathway in miRNAs-Uvrag-dependent manner provides a novel mechanism of EWSR1 deficiency-related cellular dysfunction. [BMB Reports 2015; 48(7): 371-372]

• Journal of Advanced Marine Engineering and Technology
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• v.26 no.5
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• pp.565-572
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• 2002

The design concept of diesel engines for sea-going ships has been directed to Low-speed/Long-Stroke type to improve the efficiencies of combustion and propelling. But time-delay inevitable at low speed gives much difficulties for governors to control the engine speed because they would be apt to go into unstable region especially when operating at low speed. The purpose of this paper is to study the problem of how the governor gain can be calculated dynamically in accordance with the valiance of engine speed to locate the engine still on the properly stable condition. In this study, the property of diesel engine was described as composed of combustion element including dead time and rotating element, and the ultimate gain for the speed control system to be located on the condition of stability limit was proposed based on the frequency characteristics. And the target gains with optimized stability also were proposed by giving proper margin to these ultimate conditions. The results were applied to a model system and the availability was confirmed to be satisfactory.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 1991.10a
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• pp.92-95
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• 1991

Constant false alarm rate(CFAR) processors are useful for detecting radar targets in background for which all parameters in the statistical distribution are not known and may be nonstationary. The well known "cell averging" (CA) CFAR processor is known to yield best performance in homogeneous case, but exhibits severe performance in the presence of an interfering target in the reference window or/and in the region of clutter edges. The "order statistics"(OS) CFAR processor is known to have a good performance above two nonhomogeneous cases. The modified OS-CFAR processor, known as "trimmed mean"(TM) CFAR processor performs somewhat better than the OS-CFAR processor by judiciously trimming the ordered samples. This paper proposes and analyzes the performance of a new CFAR processor called the "maximum trimmed mean"(MX-TM) CFAR processor combining the "greatest of"(GO) CFAR and TM-CFAR processors. The MAX operation is included to control false alarms at clutter edges. Our analyses show that the proposed CFAR processor has similar performance TM- and OS-CFAR processors in homogeneous case and in the precence of interfering targets, but can control the false rate in clutter edges. Simulation results are presented to demonstrate the qualitative effects of various CFAR processors in nonhomogeneous clutter environments.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.276-282
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• 1998

Retinoids regulate a wide variety of biological processes such as cellular proliferation and differentiation in many cell types. They have also shown to stimulate replication of several viruses including human cytomegalovirus (CMV). Retinoid signalling pathway involves two distinct subfamilies of nuclear receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs) that bind to specific retinoic acid response elements (RAREs) in the promoter regions of retinoid-target genes. Here, we characterized RAREs in the regulatory regions of the CMV and of the hepatitis B vi.us (HBV). The viral RAREs, i.e., CMV-RARE and HBV-RARE, are composed of two consensus RARE half-sites (A/GGGTCA) arranged as a direct repeat separated by 5-bp and 1-bp, respectively. The RAREs were activated by both RAR/RXR heterodimers and RXR homodimers in transient transfection experiments. We also found that COUP-TF$\alpha$ (chicken ovalbumin upstream promoter-transcription factor u) and COUP-TF$\beta$ repressed the retinoid response of the viral elements. Further we demonstrated that previously known retinoid antagonist, SRI 1330, repressed retinoid-induced transactivation of the CMV-RARE. These results implicate Vitamin A, it's nuclear receptors and COUP-TFs as important regulators of the CMV and HBV pathogenesis and the SRl1330 as potential negative modulator of such retinoid-dependent processes.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.1
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• pp.101-109
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• 2002

Two perforated plates are used to investigate local heat/mass transfer characteristics in an impingement/effusion cooling system. A naphthalene sublimation method is conducted to determine the local heat/mass transfer coefficients on the upward facing surface of the effusion plate. Two plates are placed in parallel position with gap distances of 1, 2, 4 and 6 times of effusion hole diameter. The effects of hole arrangements of the plates are studied fur staggered, square, and hexagonal arrays. The experiments are conducted at Reynolds number of 10,000 based on the effusion hole diameter. The results show that the smaller hole size in the staggered array has the higher transfer coefficients on the stagnation region due to the formation of higher momentum flows through the impingement holes. In the square array, heat/mass transfer on the target plate is more uniform as the number of impingement holes increases. High and uniform heat/mass transfer coefficients are obtained for the hexagonal array.

• Proceedings of the Korean Vacuum Society Conference
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• 1994.06a
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• pp.92-92
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• 1994

Relative intensities of photons emitted from tilted carbon foils have been measured in the wavelength region 300800 nm by 0,6-2,4 MeV $H^{+}\;and\;He^{+}$ ion impacts, Ions were directed onto target surfaces at tilt angles with respect to the sllrface normal, Experimental results support the model that the observed continuum radiation is emitted from the exited carbon foil itself. At each incident projectile energy, the photon intensities of continuum spectra for tilted carbon foi Is were compatred to the stoppi ng powers of carbon for $H^{+}\;and\;He^{+}$ ions, It was found that the photon emission intensity for $H^{+}$ ion is linearly proportional to the stopping power, whereas that for $He^{+}$ ions is proportional to a higher power of the stopping power, and that this tendency increases wi th decreasing velocity of the projectiIes[1, 2].[1, 2].

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.9
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• pp.3432-3448
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• 2015

Interference can cause serious problems in our daily life. Traditional ways in localizing a target can't work well when it comes to the source of interference for it may take an uncooperative or even resistant attitude towards localization. To tackle this issue, we take the BPSN (Binary Proximity Sensor Networks) and consider a passive way in this paper. No cooperation is needed and it is based on simple sensor node suitable for large-scale deployment. By dividing the sensing field into different patches, when enough patches are formed, good localization accuracy can be achieved with high resolution. Then we analyze the relationship between sensing radius and localization error, we find that in a finite region where edge effect can't be ignored, the trend between sensing radius and localization error is not always consistent. Through theoretical analysis and simulation, we explore to determine the best sensing radius to achieve high localization accuracy.

• Journal of Korean Society of Rural Planning
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• v.19 no.1
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• pp.33-41
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• 2013

Community building has been carried out from around the year 2000 by various statutes and government policies in Korea. This study suggested direction of the future for rural community building as surveyed cases of completed four villages in Gurye-county. In order to achieve this study's objectives, investigated previous studies and interviewed 75 person's residents in cases villagers. The target villages are Sangsa, Omi, Chamsaimigol and Artists village. As survey results, four villages utilized local resources, most of villages were focused perform hardware. On the other hand, Chamsaimigol was parallel software. In addition, communities didn't form and not agree with concept of community building as culture, education, welfare, etc., also didn't creation the case of village income. but active village as base development. Therefor, proposed the point to education, culture and welfare, base development and generating of income as directions for future rural community building. These directions are consistent with the concept of community building and the goal that improve the quality of life of residents ultimately through community building.

• International Journal of Industrial Entomology and Biomaterials
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• v.23 no.1
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• pp.137-141
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• 2011

A previous data was provided information for tissuespecific expression genes by means of whole-genome oligonucleotide microarray in the silkworm. We analyzed the tissue-specific expression patterns in the hemocyte tissue on 5 days of 5th instar larvae during the development of $B.$ $mori$. Total 5 candidates pick out from the $Bombyx$ $mori$ Microarray Database (BmMDB; http://silkworm.swu.edu.cn/microarray). To verify the hemocyte-specific expression, we analyzed by semi-quantitative and real-time quantitative RT-PCR using the highly expressed endogenous $Actin$ RNA as an intrinsic reference. In this study, we confirmed that one gene-sw17255- out of 5 candidates expressed in the hemocyte tissue, which was consistent with the previous data. Circulating hemocytes in the body fluid of the $B.$ $mori$ are most powerful target organ for producing biomaterials. We need further studies to find hemocyte-specific promoter region from sw17255 gene. Finally, this result can be applied in creating transgenic silkworms as a biomedical insect.