• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.101-110
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• 2017

The National Emergency Management Agency (NEMA) presented the disaster prevention performance target rainfall (DPPTR) for disaster prevention. The estimation criteria for DPPTR is a 10 year cycle. On the other hand, the target rainfall recalculated every 10 years is difficult to reflect the current change in rainfall on climate change. In this study, the probability of precipitation using the recent rainfall data was prepared and the weights according to socio-economic criteria reflecting the urban characteristics and adjusted probability rainfall criteria were applied to the results. The difference between the existing target rainfall and recalculated result was compared. The input data for the estimated probability rainfall was selected from 6 points located in the rainfall observing station of Chungcheongnam-do, Daejeon region. As a result of the estimation, in the case of upward probability precipitation weight, some similar areas were observed. On the other hand, there were a few cases of upward or downward changes within 10 mm. Considering the rainfall variability and uncertainty due to climate change, the existing target rainfall does not present the condition properly. Therefore, hydrological designers need to calculate the target rainfall, reflecting the present condition.

• Journal of Korean Neurosurgical Society
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• v.40 no.5
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• pp.342-345
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• 2006

Objective : Gamma Knife Surgery[GKS] for the management of pineal region tumors is challengeable strategy as direct access to this area is not easy. The experiences of pineal region tumor patients treated with GKS were analyzed to evaluate the effectiveness. Methods : Seven patients with tumors in the pineal region were treated with GKS between September 1998 and May 2005. The histological diagnosis were pineal parenchymal tumor [2 patients], low-grade astrocytoma [2 patients], immature teratoma [1 patient], and choriocarninoma [1 patient]. One patient was diagnosed as metastatic brain tumor based on histological diagnosis for primary site and brain imaging study. The median marginal dose was 15Gy [range; $11{\sim}20$] at the 50% isodose line. The median target volume was $2.5cm^3$ [range; $0.8{\sim}12.5$]. The median clinical follow up period was 29 months [range; $13{\sim}93$] and the median radiological follow up period was 18 months [range; $6{\sim}73$]. Results : Tumor volume measured in follow-up images showed reduction in six patients, disappearance in one. No adverse effect due to GKS was found during the follow-up period. The performance status was preserved in all patients except one who died due to progression of primary cancer in spite of controlled metastatic brain lesion. Conclusion : Gamma Knife Surgery can be applied to pineal region tumors irrespective of their histology whenever surgery is not indicated.

• Journal of Soil and Groundwater Environment
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• v.23 no.1
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• pp.92-105
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• 2018

In this study, the projected land use area in 2030 for major crop production was estimated in Jeju Island using land cover map, and corresponding agricultural water demand for 40 sub-regions was quantitatively assessed using the future climate change scenario (RCP 4.5). Estimated basic unit of water demand in 2030 was the highest in the western region, and the lowest in the eastern region. Monthly maximum agricultural water demand analysis revealed that water demand in August of 2030 substantially increased, suggesting the climate of Jeju Island is changing to a subtropical climate in 2030. Agricultural water demand for sub-region in 2030 was calculated by multiplying the target area of the water supply excluding the area not in use in winter season by the basic unit of water demand, and the maximum and minimum values were estimated to be $306,626m^3/day$ at Seogwipo downtown region and $77,967m^3/day$ at Hallim region, respectively. Consequently, total agricultural water demand in Jeju Island in 2030 was estimated to be $1,848,010m^3/day$.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.45 no.2
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• pp.29-36
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• 2008

In this paper we propose a real-time method to estimate a pointing region from two camera images. In general, a pointing target exists in the face direction when a human points to something. Therefore, we regard the direction of pointing as the straight line that connects the face position with the fingertip position. First, the method extracts two points in the face and the fingertips region by using detecting the skin color of human being. And we used the 3D geometric information to obtain a pointing detection and its region. In order to evaluate the performance, we have build up an ICIGS(Interactive Cinema Information Guiding System) with two camera and a beam project.

• Journal of The Korean Astronomical Society
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• v.39 no.4
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• pp.107-114
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• 2006

We conducted an analysis of a selected region from the FCRAO $^{12}CO$ Outer Galaxy Survey. The selected region is located between galactic longitude $117^{\circ}$ and $124^{\circ}$ with the velocity of -23 km $s^{-1}. Molecular clouds in this region show a peculiar velocity field, protruding from the Local Arm population. The selected region is divided into 7 clouds by spatial location. Though we were not able to identify the direct driving source for peculiar velocity of our target region, we find that there are several internal YSOs or star forming activities; there are many associated sources like an outflows, a high-mass protostellar candidate and $H_2O$ maser sources. We attribute the driving energy source to older generation of episodic star formation. Masses of main clouds(cloud 1-4) estimated using a conversion factor from $^{12}CO$ luminosity are larger than $10^4M_{\odot}$. Other components have a small mass as about $10^3M_{\odot}$. Among main clouds, cloud 2 and 4 seem to be marginally gravitational bound systems as their ratio of $M_{CO}$ to $M_{VIR}$ is about $2{\sim}3$, and the internal velocity dispersion is larger than the centroid velocity dispersion. Total mass estimated using a conversion factor from $^{12}CO$ luminosity is $7.9{\times}10^4M_{\odot}$.

• Journal of the Korean Geographical Society
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• v.38 no.2
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• pp.324-334
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• 2003

The essential Policy for solving the problems of the Seoul Metropolitan Region is the relocation of national pivotal functions into the non-Capital Region. The decentralization of pivotal functions should be pursued at the national level. National public institutions should be moved according to the characteristics of the institution itself and the regional function and specialization. Primarily, after selecting target institutions from the administrations at the vice-ministerial level, affiliated organizations, government-funded agencies, and institutions invested tv governments, we need to develop various measures to diminish the problems and obstacles resulted from the relocation of public sector. The construction of the new administration capital city is one of the alternatives which solve the problems of the Seoul Metropolitan Region and improve the regional inequality. It is very much important that the Korean citizens agree to the construction of the new administration capital city.

• Journal of Microbiology and Biotechnology
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• v.23 no.9
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• pp.1293-1303
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• 2013

Antibiotic resistance of soilborne Acinetobacter species has been poorly explored. In this study, norfloxacin resistance of a soil bacterium, Acinetobacter oleivorans DR1, was investigated. The frequencies of mutant appearance of all tested non-pathogenic Acinetobacter strains were lower than those of pathogenic strains under minimum inhibitory concentration (MIC). When the quinolone-resistance-determining region of the gyrA gene was examined, only one mutant (His78Asn) out of 10 resistant variants had a mutation. Whole transcriptome analysis using a RNA-Seq demonstrated that genes involved in SOS response and DNA repair were significantly up-regulated by norfloxacin. Determining the MICs of survival cells after norfloxacin treatment confirmed some of those cells were indeed persister cells. Ten colonies, randomly selected from among those that survived in the presence of norfloxacin, did not exhibit increased MIC. Thus, both the low mutation frequency of the target gene and SOS response under norfloxacin suggested that persister formation might contribute to the resistance of DR1 against norfloxacin. The persister frequency increased without a change in MIC when stationary phase cells, low growth rates conditions, and growth-deficient dnaJ mutant were used. Taken together, our comprehensive approach, which included mutational analysis of the target gene, persister formation assays, and RNA sequencing, indicated that DR1 survival when exposed to norfloxacin is related not only to target gene mutation but also to persister formation, possibly through up-regulation of the SOS response and DNA repair genes.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2006.11a
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• pp.198-198
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• 2006

Tin doped $In_2O_3$ sputtering target is widely used to produce a various kinds of flat panel display because of high transmittance in visible region and high electrical conductivity. In2O3 and SnO2 powders were prepared by a homogeneous precipitation method using metal source, respectively, the calcining and sintering behavior of the indium-tin oxide(In2O3-SnO2) composite powders were studied. The tin oxide(SnO2) dispersion condition in ITO sputtering target was improved by increasing calcining temperature. And the tin oxide dispersion was also improved by reducing the tin oxide contents in the ITO target from 30 to 5wt%. SnO2 dispersion and densification of ITO target is very difficult to control due to sublimation of SnO2 at over 1150C.

• Progress in Superconductivity and Cryogenics
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• v.15 no.3
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• pp.40-48
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• 2013

Cryoablation device is a surgical instrument to produce the cooling effect to destroy detrimental biological tissue by utilizing low temperature around 110 K. Usually, this device has the concentrated cooling region, so that it is suitable for concentrated and thick target. Accordingly, it is hard to apply this device for the target which is distributed and thin target. In this study, the design procedure of a closed-loop cryoablation device with multiple J-T expansion part is developed for the treatment of incompetent of great saphenous vein. The developed cyoablation device is designed with the analysis of 1-dimensional (1-D) bio-heat equation. The energy balance is considered to determine the minimum mass flow rate of refrigerant for consecutive flow boiling to develop the uniform cooling temperature. Azeotropic mixed refrigerant R410A and zeotropic mixed refrigerant (MR) of R22 ($CHClF_2$) and R23 ($CHF_3$) are utilized as operating fluids of the developed cryoablation device to form the sufficient temperature and to verify the quality of the inside of cryoablation probe. The experimental results of R410A and the zeotropic MR show the temperature non-uniformity over the range are $244.8K{\pm}2.7K$ and $239.8K{\pm}4.7K$ respectively. The experimental results demonstrate that the probe experiences the consecutive flow boiling over the target range of 200 mm.

• BMB Reports
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• v.43 no.6
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• pp.438-444
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• 2010

Dnd (dead end) gene encodes an RNA binding protein and is specifically expressed in primordial germ cells (PGCs) as a vertebrate-specific component of the germ plasma throughout embryogenesis. By utilizing a technique of specific nucleic acids associated with proteins (SNAAP), 13 potential target mRNAs of zebrafish Dnd (ZDnd) protein were identified from 8-cell embryo, and 8 target mRNAs have been confirmed using an RT-PCR analysis. Of the target mRNAs, the present study is focused on the regulation of geminin, which is an inhibitor of DNA replication. Using electrophoretic mobility shift assay (EMSA), we demonstrated that ZDND protein bound the 67-nucleotide region from 864 to 931 in the 3'UTR of geminin mRNA, a sequence containing 60.29% of uridine. Results from a dual-luciferase assay in HEK293 cells showed that ZDND increases the translation of geminin. Taken together, the identification of target mRNA for ZDnd will be helpful to further explore the biological function of Dnd in zebrafish germ-line development as well as in cancer cells.