• BMB Reports
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• v.50 no.11
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• pp.539-545
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• 2017

The Integrated Stress Response (ISR) refers to a signaling pathway initiated by stress-activated $eIF2{\alpha}$ kinases. Once activated, the pathway causes attenuation of global mRNA translation while also paradoxically inducing stress response gene expression. A detailed analysis of this pathway has helped us better understand how stressed cells coordinate gene expression at translational and transcriptional levels. The translational attenuation associated with this pathway has been largely attributed to the phosphorylation of the translational initiation factor $eIF2{\alpha}$. However, independent studies are now pointing to a second translational regulation step involving a downstream ISR target, 4E-BP, in the inhibition of eIF4E and specifically cap-dependent translation. The activation of 4E-BP is consistent with previous reports implicating the roles of 4E-BP resistant, Internal Ribosome Entry Site (IRES) dependent translation in ISR active cells. In this review, we provide an overview of the translation inhibition mechanisms engaged by the ISR and how they impact the translation of stress response genes.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.43.2-43.2
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• 2013

AGN are known for irregular variability on all time scales, down to intra-day variability with relative variations of a few percent within minutes to hours. In the shortest time scale of AGN activity, unexplored territory still exists: first, the existence of a shortest time scale of AGN activity and secondly the shape of high frequency end of AGN power spectrum. Also the spectral variations at the shortest timescale. Here, we present the preliminary results of AGN fast photometry performed with Korean VLBI Network(KVN). Observations were done in a 'anti-correlated' mode using two antennas, with always either one antenna pointing at the target. This results in an effective time resolution of 3 minutes. We used all four KVN frequencies, 22, 43, 86, and 129 GHz, in order to trace spectral variability. We have been able to derive high-quality light curves for 3C111 and 3C279 at 22 and 86 GHz observed on 31st of May and 30th of Nov. in 2012. We are currently performing detailed statistical analysis in order to assess the levels of variability or the corresponding upper limits.

• Journal of Astronomy and Space Sciences
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• v.22 no.1
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• pp.47-58
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• 2005

This paper addresses development of the ultra-light analog sun sensors for small satellite applications. The sun sensor is suitable for attitude determination for small satellite because of its small, light, low-cost, and low power consumption characteristics. The sun sensor is designed, manufactured and characteristic-tested with the target requirements of ${\pm}60^{\circ}$ FOV (Field of View) and pointing accuracy of ${\pm}2^{\circ}$. Since the sun sensor has nonlinear characteristics between output measurement voltage and incident angle of sunlight, a higher order calibration equation is required for error correction. The error was calculated by using a polynomial calibration equation that was computed by the least square method obtained from the measured voltages vs. angles characteristics. Finally, the accuracies of 1-axis and 2-axes sun sensors, which consist of 2 detectors, are compared.

• Structural Engineering and Mechanics
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• v.34 no.6
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• pp.739-753
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• 2010

Pointing to the design requirement of prestressed space grid structure being the target cable force, the pretension scheme decision analysis method is studied when there's great difference between structural actual state and the analytical model. Based on recursive formulation of cable forces, the simulative recursive system for pretension process is established from the systematic viewpoint, including four kinds of parameters, i.e., system initial value (structural initial state), system input value (tensioning control force scheme), system state parameters (influence matrix of cable forces), system output value (pretension accomplishment). The system controllability depends on the system state parameters. Based on cable force observation values, the influence matrix for system state parameters can be calculated, making the system controllable. Next, the pretension scheme decision method based on cable force observation values can be formed on the basis of iterative calculation for recursive system. In this way, the tensioning control force scheme that can meet the design requirement when next cyclic supplemental tension finished is obtained. Engineering example analysis results show that the proposed method in this paper can reduce a lot of cyclic tensioning work and meanwhile the design requirement can be met.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2009.01a
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• pp.742-745
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• 2009

This paper proposes a wireless LAN antenna system that tracks an object automatically by using image-based tracking. The proposed system consists of a camera and a pan-tilt unit in addition to a directional wireless LAN antenna. The camera and the directional antenna are set in same direction and they are set on the pan-tilt unit. A target object which has a wireless LAN receiver is tracked by using images captured by the camera. And the directional antenna faces in same direction as the camera by the pan-tilt unit. Therefore, the directional antenna keeps pointing the receiver, and a transmitting efficiency is improved. A result of a fundamental experiment shows that a receiver attached to a flying airship was tracked by a prototype of the proposed antenna system. The airship flied about, and the proposed antenna system was set on a roof of a building. The experimental result indicates an effectiveness of the proposed system compared to the conventional directional LAN antenna.

• Publications of The Korean Astronomical Society
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• v.28 no.1
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• pp.1-6
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• 2013

Real-time data reduction pipeline for the Korea Microlensing Telescope Network (KMTNet) was developed by Korea Astronomy and Space Science Institute (KASI). The main goal of the data reduction pipeline is to find variable objects and to record their light variation from the large amount of observation data of about 200 GB per night per site. To achieve the goal we adopt three strategic implementations: precision pointing of telescope using the cross correlation correction for target fields, realtime data transferring using kernel-level file handling and high speed network, and segment data processing architecture using the Sun-Grid engine. We tested performance of the pipeline using simulated data which represent the similar circumstance to CTIO (Cerro Tololo Inter-American Observatory), and we have found that it takes about eight hours for whole processing of one-night data. Therefore we conclude that the pipeline works without problem in real-time if the network speed is high enough, e.g., as high as in CTIO.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.4
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• pp.55-60
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• 2012

When operating a surveillance system in the maritime environment, its stabilization performance is degraded due to undesirable disturbance motions. For accurate target pointing of a 2-axes surveillance system on shipboard, the kinematic stabilization is first applied, which compensates a deviated motion via coordinate transformations of attitude information. Resultantly, the stabilization error is no longer reduced due to less accuracy of a MEMS sensor and kinematic constraint, leading to introduction of the image stabilization as a complementary function. And for real-time execution of the present dual stabilization scheme, a HILS (Hardware In the Loop Simulation) test bed including 6-dof motion simulator has been constructed, and through the obtained HILS data, it has been confirmed that the stabilization is successfully.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.11
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• pp.2045-2048
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• 2006

This study presented the non-contact human interface using by CdS sensor array. We are pointing the light on the target to measure the value. We converted the CdS sensors value to digital value and applied the digital value to set the coordinate value from the ratio of it to the adjacent sensors. The indicated coordinate-value is presented on the PC screen by LabVIEW The experimental result, we could confirm the right value divided between each sensor distance into In parts.

• Korean Journal of Cognitive Science
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• v.11 no.2
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• pp.37-51
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• 2000

The present study compared computer users target-selection response patterns when the targets were varied in terms of their relative location and distance from the current position of the cursor. In Experiment 1, where the mouse was used as an input device, the effects of different directions and distances of simple target(small rectangle) on target-selection response were investigated. The results of Experiment 1 can be summarized as follows: (1) Overshooting was more frequent than either undershooting or correct movement and (2) this tendency was more prominent when the targets were presented in the oblique direction or in farther location from the current cursor position. (3) Although the overshooting and undershooting were more frequent in the oblique direction, the degree of deviation was larger in horizontal and vertical direction. (4) Time spent in moving the mouse rather than that spent in planning, calibrating or clicking was found to be the most critical factor in determining total response time. In Experiment 2, effects of the font size and line-height of the target on target-selection response were compared with regard to two types of input devices(keyboard vs. mouse). The results are as follows: (1) Mouse generally yielded shorter target-selection time than keyboard. but this tendency was reversed when the targets were presented in horizontal and vertical directions. (2) In general, target-selection time was the longest in the condition of font size of 10 and line-height of 100%, and the shortest in the condition of font size of 12 and line-height of 150%. (3) When keyboard was used as the input device, target-selection time was shortest in the 150% line-height condition, whereas in the mouse condition, target-selection time tended to be increased as the line-height increased. which resulted in the significant interaction effect between input device and line-height. Finally, several issues relating to human-computer interaction were discussed based on the results of the present study.

• Korean Journal of Optics and Photonics
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• v.31 no.6
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• pp.274-280
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• 2020

In this paper, the effect of atmospheric turbulence is numerically modeled and analyzed via a phase-screen model, in regard to long-range optical energy transfer using coherent beam combination. The coherent-beam-combination system consists of three channel beams pointing at a target at a distance of 1-2 km. The phase and propagation direction of each channel beam are assumed to be corrected in an appropriate manner, and the atmospheric turbulence that occurs while the beam propagates through free space is quantified with a phase-screen model. The phase screen is statistically generated and constructed within the range of fluctuations of the structure constant Cn2 from 10-15 to 10-13 [m-2/3]. Particularly, in this discussion the shape, distortion, and combining efficiency of the 3-channel combined beam are calculated at the target plane by varying the structure constant used in the phase-screen model, and the effect of atmospheric turbulence on beam-combination efficiency is analyzed. Analysis with this numerical model verifies that when coherent beam combination is used for long-range optical energy transfer, the received power at the target can be at least three times the power obtainable by incoherent beam combination, even for maximal atmospheric fluctuation within the given range. This numerical model is expected to be effective for analyzing the effects of various types of atmospheric-turbulence conditions and beam-combination methods when simulating long-range optical energy transfer.