• 한국군사과학기술학회지
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• 제10권2호
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• pp.148-151
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• 2007

The CF(Counter-fire) is neutralizing enemy's all command control systems and fire support elements. It will weaken a battle continuous ability and an intension to fight. At the beginning of the CF is obtaining locations of targets using various detection assets. CF command center processes acquired target information and send it to attacking equipments. The targets are classified into two classes, preplanned target and target of opportunity The target of opportunity is potential threaten, so it needs to take a immediate and exact process for determining location of target of opportunity. This paper proposes the real-time processing algorithm for offensive weapons to strike target of opportunity, and presents the result of its performance.

• Biomolecules & Therapeutics
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• 제22권5호
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• pp.371-383
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• 2014

The nematode Caenorhabditis elegans (C. elegans) offers a unique opportunity for biological and basic medical researches due to its genetic tractability and well-defined developmental lineage. It also provides an exceptional model for genetic, molecular, and cellular analysis of human disease-related genes. Recently, C. elegans has been used as an ideal model for the identification and functional analysis of drugs (or small-molecules) in vivo. In this review, we describe conserved oncogenic signaling pathways (Wnt, Notch, and Ras) and their potential roles in the development of cancer stem cells. During C. elegans germline development, these signaling pathways regulate multiple cellular processes such as germline stem cell niche specification, germline stem cell maintenance, and germ cell fate specification. Therefore, the aberrant regulations of these signaling pathways can cause either loss of germline stem cells or overproliferation of a specific cell type, resulting in sterility. This sterility phenotype allows us to identify drugs that can modulate the oncogenic signaling pathways directly or indirectly through a high-throughput screening. Current in vivo or in vitro screening methods are largely focused on the specific core signaling components. However, this phenotype-based screening will identify drugs that possibly target upstream or downstream of core signaling pathways as well as exclude toxic effects. Although phenotype-based drug screening is ideal, the identification of drug targets is a major challenge. We here introduce a new technique, called Drug Affinity Responsive Target Stability (DARTS). This innovative method is able to identify the target of the identified drug. Importantly, signaling pathways and their regulators in C. elegans are highly conserved in most vertebrates, including humans. Therefore, C. elegans will provide a great opportunity to identify therapeutic drugs and their targets, as well as to understand mechanisms underlying the formation of cancer.

• 한국인터넷방송통신학회논문지
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• 제12권5호
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• pp.141-151
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• 2012

본 논문은 할당 문제의 최적해를 찾는 대표적인 Hungarian 보다 간단히 최적해를 구하는 알고리즘을 제안하였다. Hungarian 알고리즘은 행과 열의 최소 비용을 선택하고 각 비용에서 최소 비용을 뺀다. 다음으로 0을 모두 포함하는 최소한의 선이 행의 개수 가 될 때까지 수행한다. 반면에 제안된 알고리즘은 단지 행에 대해 최소 비용을 선택한다. 다음으로 열에 대해 2개 이상 선택된 열을 출발지로, 하나도 선택되지 않은 열을 목적지로하여 출발지의 비용에서 목적지의 최소 비용과의 차이인 기회비용이 가장 큰 비용은 고정시키고 기회비용이 보다 작은 비용들을 다음으로 큰 비용으로 이동시키는 방법을 적용하였다. 제안된 방법을 25개의 균형 할당과 7개의 불균형 할당 문제에 적용하여 Hungarian 알고리즘과 동일한 최적해를 구하는데 성공하였다. 제안된 알고리즘은 Hungarian 알고리즘의 수행 복잡도 $O(n^3)$를 $O(n^2)$로 개선하였으며, 불균형을 균형 할당 문제로 변환시키는 과정도 수행하지 않는 단순한 알고리즘이다. 따라서 할당 문제의 Hungarian 알고리즘을 대체시킬 수 있을 것이다.

• 벤처창업연구
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• 제6권4호
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• pp.39-57
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• 2011

본 논문***은 청년창업가의 창업기회원천을 분석하여 기회탐색의 성격을 연구함을 그 목적으로 한다. 이를 위해 창업기회요인으로 창업의지, 창업기회 발생배경, 창업기회단서, 창업기회단서의 접촉상황, 사업아이디어 활용, 창업자본금 중 자기자본비율의 여섯 가지 변수를 사용하였다. 탐색적 조사를 위하여 서울시 "청년창업 1000프로젝트" SBA 강남청년창업센 터의 청년창업가를 대상으로 설문자료 182개를 획득하였고, SPSS Win Ver. 18.0 프로그램을 사용하여 빈도분석과 변수간 관계성을 검정하기 위하여 독립성 검정을 하였다. 연구결과는 첫째, 창업의지의 성격 조사에서 의도적 창업이 87.4%의 비율로 기존 연구와는 차별된 결과를 보여주었다. 둘째, 창업기회 발생배경은 교육을 통한 비율이 기존 연구에서보다 확연히 증가되었음을 확인할 수 있었다. 셋째, 창업기회단서의 접촉상황을 조사한 결과는 기존연구와 달리 응답자의 절반에 가까운 숫자가 탐색적으로 창업에 접근하였던 것으로 조사되었다. 본 연구결과는 청년창업가들의 창업기회 유형을 이해하여 청년창업가로 하여금 안정적이고 성공적인 창업에 이룰 수 있도록 정책적 지원 방안을 제시한다는 점에서 그 시 사점이 있다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 추계학술대회 논문집
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• pp.1525-1538
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• 2008

Currently, it has been a fashion to include RAMS of rolling stock in the order for purchasing the rolling stock. However, it's only to suggest a qualitative value or an ideal target without giving or demonstrating actual RAMS target, with only demonstrating passive RAMS by the data provided by the manufacturer. In the case of KTX project of 100 cars of KTX-II contracted in June 2006, their target has been suggested from the previous RAMS application standard and it aimed to achieve the reliability level of equivalent high speed rolling stock. Afterward, as actual KTX-II RAMS Plan and RAMS Demonstration Plan has been prepared and approved, it has been the first problem to secure the reliability and safety in order to introduce the new high speed rolling stock(KTX-II) successfully and we actually tried to apply overseas RAMS standard, KTX samples, electric railcar MTRC and rolling stock samples. This Report was dealt world trends of Railway RAMS standard, KTX-II RAMS Specifications, the present condition of KTX-II RAMS performance and development a way of KTX-II RAMS, We hope the "KTX-II RAMS Application Standard for Safety of Passenger Transportation Service" is served as an opportunity for the basic research for establishing and demonstrating RAMS target of components or parts composing the rolling stock system.

• 시큐리티연구
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• 제6호
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• pp.327-340
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• 2003

As a countermeasure under accidental occurrence situation, First, as application form of martial arts, A security guard foster ability that can protect a target person of guard and own body under accidental occurrence situation through incessant martial arts practice. To achieve this purpose, incessant training mental power and physical strength reinforcement should be kept on to prevent, therefore make a safety control function for such as weapon, small arms, explosive, vehicles terror etc. happened under accidental occurrence situation. Second, according to the contents of training based on the classification category of martial arts for security guard under accidental situation, a security guard must keep safety distance necessarily lest a target person of gurad should be attacked by attacker, therefore, intercept an attack opportunity if a safety distance between a target person of guard and attacker is not kept. Third, It is to practice confrontation techniques based on the type of attack. A security guard must develp situation disposal ability that can cope properly with the attack using empty hands, murderous weapon, small arms, explosive by case or individual or mass of threat that impose danger and injury in a target person's body of guard.

• Journal of Korea Trade
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• 제25권1호
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• pp.65-88
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• 2021

Purpose - This paper aims to examine the determinants of SWFs' investment in Asian countries and to identify consistent investment patterns of SWFs in specific target firms from Asia, particularly China and South Korea. Design/methodology - This study extends the Tobin's Q model to examine the relationship between SWF investments in target firms and their returns with other firm-level control variables. We collect consistent data on SWF investments and the matched firm-level data on target firms, which of observation is 1,512 firms (333 in South Korea and 1,179 in China) targeted by 20 SWF sources during 1997-2017. The panel random effect model is used to estimate the extended Tobin's Q model. The robustness of the estimations is tested by the simultaneous equation models and the panel GEE model. Findings - The evidence shows that sovereign wealth funds are more inclined to invest in the financial sector with a monopoly position and in large firms with higher growth opportunity and superior cash asset ratios in China. In contrast to their investments in China, sovereign wealth funds in South Korea prefer to invest in strategic sectors, such as energy and information technology, and in large firms with high performance and low leverage. Sovereign wealth funds' investments tend to significantly improve the target firm's performance measured by sales growth and returns in both Korea and China. Originality/value - The existing literature focuses on examining the determination of SWFs investment in the developed countries, such as Europe and the United States. Our paper contributes to the literature in three ways; first, we analyzes case studies of SWF investments in Asian markets, which are less developed and riskier. Second, we examine whether the determination of SWF investment in Asian target firms depends on the different time periods, on types of sources of SWFs, and on acquiring countries. Third, our research uses vast sample data on target firms in longer time periods (1997-2017) than other previous studies on the SWFs for Asian markets.

• 영어어문교육
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• 제11권2호
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• pp.91-110
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• 2005

Many Korean EFL (English as a Foreign Language) students do not have sufficient opportunity to develop cultural knowledge and information in their classrooms. EFL teachers also tend to ignore the teaching of culture. Even though culture is taught, it simply tends to deliver "fact-only" information from the viewpoint of a "tourist level rather than cultural awareness by comparing native with target cultural references. Teaching target cultural knowledge and information should be delivered within the native cultural frame, and teaching of culture must be an integral part of teaching and learning English. The research methodology was quantitative. Quantitative data was gathered from 83 Korean EFL teachers and 286 EFL students by questionnaire. Findings indicated that three of these independent variables (cultural inequality, English-only instruction, and Unoism) were significantly and inversely related to integration of culture.

• 한국경영과학회지
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• 제36권1호
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• pp.69-84
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• 2011

In this study, based on the principal-agent paradigm, we investigate a joint cost reduction activity in a buyer-supplier supply chain where a buyer motivates its operations department and a supplier to reduce the supply chain's production cost. We construct a benefit-sharing model based on the target cost scheme, a basic philosophy in practice which has not been explored in previous studies. The model also incorporates various supply chain issues such as the cooperation of multiple agents, the opportunity loss, and the degree of strategic relationship between the buyer and the supplier. Based on the analysis of the principal-agent model, we investigate the benefit-sharing rule to control agents' actions, and we also provide important managerial implications into supply chain practices via extensive comparative static analyses.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권1호
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• pp.1-11
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• 2018

The emergence of mucosal healing as a treatment goal that could modify the natural course of Crohn's disease and the accumulating evidence showing that biologics are most effective in achieving mucosal healing, along with the success of early treatment regimens for rheumatoid arthritis, have led to the identification of early Crohn's disease and development of the concept of catching the therapeutic window during the early disease course. Thus, an increasing number of pediatric gastroenterologists are adopting an early biologic treatment strategy with or without an immunomodulator. Although early biologic treatment is effective, cost and overtreatment are issues that limit its early use. Currently, there are insufficient data on who will benefit most from early biologics, as well as on who will not need early or even any biologics. For now, top-down biologics should be considered for patients with currently known high-risk factors of poor outcomes. For other patients, close, objective monitoring and accelerating the step-up process by means of a treat-to-target approach seems the best way to catch the therapeutic window in early pediatric Crohn's disease. The individual benefits of immunomodulator addition during early biologic treatment should be weighed against its risks and decision on early combination treatment should be made after comprehensive discussion with each patient and guardian.