• Journal of the Korea Institute of Military Science and Technology
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• v.10 no.2
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• pp.148-151
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• 2007

The CF(Counter-fire) is neutralizing enemy's all command control systems and fire support elements. It will weaken a battle continuous ability and an intension to fight. At the beginning of the CF is obtaining locations of targets using various detection assets. CF command center processes acquired target information and send it to attacking equipments. The targets are classified into two classes, preplanned target and target of opportunity The target of opportunity is potential threaten, so it needs to take a immediate and exact process for determining location of target of opportunity. This paper proposes the real-time processing algorithm for offensive weapons to strike target of opportunity, and presents the result of its performance.

• Biomolecules & Therapeutics
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• v.22 no.5
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• pp.371-383
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• 2014

The nematode Caenorhabditis elegans (C. elegans) offers a unique opportunity for biological and basic medical researches due to its genetic tractability and well-defined developmental lineage. It also provides an exceptional model for genetic, molecular, and cellular analysis of human disease-related genes. Recently, C. elegans has been used as an ideal model for the identification and functional analysis of drugs (or small-molecules) in vivo. In this review, we describe conserved oncogenic signaling pathways (Wnt, Notch, and Ras) and their potential roles in the development of cancer stem cells. During C. elegans germline development, these signaling pathways regulate multiple cellular processes such as germline stem cell niche specification, germline stem cell maintenance, and germ cell fate specification. Therefore, the aberrant regulations of these signaling pathways can cause either loss of germline stem cells or overproliferation of a specific cell type, resulting in sterility. This sterility phenotype allows us to identify drugs that can modulate the oncogenic signaling pathways directly or indirectly through a high-throughput screening. Current in vivo or in vitro screening methods are largely focused on the specific core signaling components. However, this phenotype-based screening will identify drugs that possibly target upstream or downstream of core signaling pathways as well as exclude toxic effects. Although phenotype-based drug screening is ideal, the identification of drug targets is a major challenge. We here introduce a new technique, called Drug Affinity Responsive Target Stability (DARTS). This innovative method is able to identify the target of the identified drug. Importantly, signaling pathways and their regulators in C. elegans are highly conserved in most vertebrates, including humans. Therefore, C. elegans will provide a great opportunity to identify therapeutic drugs and their targets, as well as to understand mechanisms underlying the formation of cancer.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.5
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• pp.141-151
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• 2012

This paper suggests more simple algorithm than Hungarian algorithm for assignment problem. Hungarian algorithm selects minimum cost of row and column, and subtracts minimum cost from each cost. Then, performs until the number of minimum lines with 0 equals the number of rows. But, the proposed algorithm selects the minimum cost for each rows only. From the start point with over 2 to the target point with null selects in column, fixes the maximum opportunity cost that the difference of the cost of starting point and target point, and moves the cost less than opportunity cost th more than previous cost. For the 25 balance and 7 unbalance assignment problems, This algorithm gets the optimal solution same as Hungarian algorithm. This algorithm improves the time complexity $O(n^3)$ of Hungarian algorithm to $O(n^2)$, and do not performs the transformation process from unbalance to balance assignment in Hungarian algorithm. Therefore, this algorithm can be alter Hungarian algorithm in assignment problem.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.6 no.4
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• pp.39-57
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• 2011

In this study, entrepreneurship opportunities, get in anywhere, in any situation, whether in respect to entrepreneurship through empirical research is to analyze. In addition, young entrepreneurs and entrepreneurship opportunities to target the source and a realistic opportunity to investigate the nature of the search in terms of effective support for young entrepreneurs and operational plans to seek the help. Entrepreneurship opportunities of the origins of the existing studies individually being taken were young entrepreneurs and selected for this study the national and international literature base, and objectives of the study to achieve the city "Young Entrepreneurs 1000 Project" participants, survey through the empirical foundation of their opportunities and entrepreneurship opportunities origins analyzed the relationship between sources. Source of entrepreneurship opportunities in the establishment will include the nature of existing research (intentional / unintentional), business opportunities generated background (source), business opportunity lead, business opportunity lead contact situation (the nature of chance encounters), the business idea was dealt with using here, a new source of opportunity factor established by adding the capital adequacy ratio of capital has been studied. Also 10 years ago by byeong-ju, Jo. entrepreneurship opportunities in Korea for the first time research on the relationship between the source after source of opportunities than in previous research literature on factors leading to the establishment an opportunity to add a set of relationships between sources were analyzed.

• Proceedings of the KSR Conference
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• 2008.11b
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• pp.1525-1538
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• 2008

Currently, it has been a fashion to include RAMS of rolling stock in the order for purchasing the rolling stock. However, it's only to suggest a qualitative value or an ideal target without giving or demonstrating actual RAMS target, with only demonstrating passive RAMS by the data provided by the manufacturer. In the case of KTX project of 100 cars of KTX-II contracted in June 2006, their target has been suggested from the previous RAMS application standard and it aimed to achieve the reliability level of equivalent high speed rolling stock. Afterward, as actual KTX-II RAMS Plan and RAMS Demonstration Plan has been prepared and approved, it has been the first problem to secure the reliability and safety in order to introduce the new high speed rolling stock(KTX-II) successfully and we actually tried to apply overseas RAMS standard, KTX samples, electric railcar MTRC and rolling stock samples. This Report was dealt world trends of Railway RAMS standard, KTX-II RAMS Specifications, the present condition of KTX-II RAMS performance and development a way of KTX-II RAMS, We hope the "KTX-II RAMS Application Standard for Safety of Passenger Transportation Service" is served as an opportunity for the basic research for establishing and demonstrating RAMS target of components or parts composing the rolling stock system.

• Korean Security Journal
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• no.6
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• pp.327-340
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• 2003

As a countermeasure under accidental occurrence situation, First, as application form of martial arts, A security guard foster ability that can protect a target person of guard and own body under accidental occurrence situation through incessant martial arts practice. To achieve this purpose, incessant training mental power and physical strength reinforcement should be kept on to prevent, therefore make a safety control function for such as weapon, small arms, explosive, vehicles terror etc. happened under accidental occurrence situation. Second, according to the contents of training based on the classification category of martial arts for security guard under accidental situation, a security guard must keep safety distance necessarily lest a target person of gurad should be attacked by attacker, therefore, intercept an attack opportunity if a safety distance between a target person of guard and attacker is not kept. Third, It is to practice confrontation techniques based on the type of attack. A security guard must develp situation disposal ability that can cope properly with the attack using empty hands, murderous weapon, small arms, explosive by case or individual or mass of threat that impose danger and injury in a target person's body of guard.

• Journal of Korea Trade
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• v.25 no.1
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• pp.65-88
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• 2021

Purpose - This paper aims to examine the determinants of SWFs' investment in Asian countries and to identify consistent investment patterns of SWFs in specific target firms from Asia, particularly China and South Korea. Design/methodology - This study extends the Tobin's Q model to examine the relationship between SWF investments in target firms and their returns with other firm-level control variables. We collect consistent data on SWF investments and the matched firm-level data on target firms, which of observation is 1,512 firms (333 in South Korea and 1,179 in China) targeted by 20 SWF sources during 1997-2017. The panel random effect model is used to estimate the extended Tobin's Q model. The robustness of the estimations is tested by the simultaneous equation models and the panel GEE model. Findings - The evidence shows that sovereign wealth funds are more inclined to invest in the financial sector with a monopoly position and in large firms with higher growth opportunity and superior cash asset ratios in China. In contrast to their investments in China, sovereign wealth funds in South Korea prefer to invest in strategic sectors, such as energy and information technology, and in large firms with high performance and low leverage. Sovereign wealth funds' investments tend to significantly improve the target firm's performance measured by sales growth and returns in both Korea and China. Originality/value - The existing literature focuses on examining the determination of SWFs investment in the developed countries, such as Europe and the United States. Our paper contributes to the literature in three ways; first, we analyzes case studies of SWF investments in Asian markets, which are less developed and riskier. Second, we examine whether the determination of SWF investment in Asian target firms depends on the different time periods, on types of sources of SWFs, and on acquiring countries. Third, our research uses vast sample data on target firms in longer time periods (1997-2017) than other previous studies on the SWFs for Asian markets.

• English Language & Literature Teaching
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• v.11 no.2
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• pp.91-110
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• 2005

Many Korean EFL (English as a Foreign Language) students do not have sufficient opportunity to develop cultural knowledge and information in their classrooms. EFL teachers also tend to ignore the teaching of culture. Even though culture is taught, it simply tends to deliver "fact-only" information from the viewpoint of a "tourist level rather than cultural awareness by comparing native with target cultural references. Teaching target cultural knowledge and information should be delivered within the native cultural frame, and teaching of culture must be an integral part of teaching and learning English. The research methodology was quantitative. Quantitative data was gathered from 83 Korean EFL teachers and 286 EFL students by questionnaire. Findings indicated that three of these independent variables (cultural inequality, English-only instruction, and Unoism) were significantly and inversely related to integration of culture.

• Journal of the Korean Operations Research and Management Science Society
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• v.36 no.1
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• pp.69-84
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• 2011

In this study, based on the principal-agent paradigm, we investigate a joint cost reduction activity in a buyer-supplier supply chain where a buyer motivates its operations department and a supplier to reduce the supply chain's production cost. We construct a benefit-sharing model based on the target cost scheme, a basic philosophy in practice which has not been explored in previous studies. The model also incorporates various supply chain issues such as the cooperation of multiple agents, the opportunity loss, and the degree of strategic relationship between the buyer and the supplier. Based on the analysis of the principal-agent model, we investigate the benefit-sharing rule to control agents' actions, and we also provide important managerial implications into supply chain practices via extensive comparative static analyses.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.1
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• pp.1-11
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• 2018

The emergence of mucosal healing as a treatment goal that could modify the natural course of Crohn's disease and the accumulating evidence showing that biologics are most effective in achieving mucosal healing, along with the success of early treatment regimens for rheumatoid arthritis, have led to the identification of early Crohn's disease and development of the concept of catching the therapeutic window during the early disease course. Thus, an increasing number of pediatric gastroenterologists are adopting an early biologic treatment strategy with or without an immunomodulator. Although early biologic treatment is effective, cost and overtreatment are issues that limit its early use. Currently, there are insufficient data on who will benefit most from early biologics, as well as on who will not need early or even any biologics. For now, top-down biologics should be considered for patients with currently known high-risk factors of poor outcomes. For other patients, close, objective monitoring and accelerating the step-up process by means of a treat-to-target approach seems the best way to catch the therapeutic window in early pediatric Crohn's disease. The individual benefits of immunomodulator addition during early biologic treatment should be weighed against its risks and decision on early combination treatment should be made after comprehensive discussion with each patient and guardian.