• 한국해양공학회지
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• 제30권3호
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• pp.177-185
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• 2016

In this study, the model developed by Hong (2012) was modified to describe the consecutive docking/undocking situation and was also applied to investigate the effect on seawater circulation in Busan port by consecutive docking/undocking at the connecting bridge of Busan port. Numerical experiments for various docking/undocking cases were performed by dumping the initial concentration within Busan Port and indicated that the concentration in Busan port becomes steady state without numerical wiggles after sufficient time (at least 20 or 30 days). In addition, it was found that the seawater circulation under ship docking was slightly reduced in comparison with that under ship undocking, and the approach time to the target concentration under all the docking cases increased in comparison with the undocking case.

• 한국지반환경공학회 논문집
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• 제11권8호
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• pp.57-63
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• 2010

본 연구에서는 준설투기장의 설계를 위하여 실내시험으로 컬럼을 이용한 준설토 침강 자중압밀시험 및 상등수에 대한 부유물 농도시험을 수행하였으며, 현장조건과 배출수의 부유물 농도를 고려한 준설투기장을 설계 검토하였다. 준설투기장 폭과 목표 부유물 농도와의 관계 검토결과, 소요면적에서는 투기장 폭이 좁고 길이가 길수록 부유물 농도가 감소함을 알 수 있었다. 또한 준설투기가 진행됨에 따라 배출되는 상등수의 부유물 농도의 변화를 예측하기 위하여 침강허용깊이의 변화에 대한 영향도 고려되어야 하며, 이는 배출수의 목표 부유물 농도가 낮을수록 더욱 중요하다.

• 한국환경보건학회지
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• 제38권3호
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• pp.269-276
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• 2012

Objectives: The purpose of this study was to provide policy directions for air pollution reduction by analyzing the variation in the characteristics of air contaminants around the Gyeonggi Province area. Methods: The data used in the study was obtained from air quality monitoring stations operated by the Gyeonggi Provincial Government. The target area was the air quality management area of the Gyeonggi Province region. Results: The concentration of $PM_{10}$ (particles measuring $10{\mu}m$ or less) in 2009 was $60{\mu}g/m^3$, which has been reduced by about 2.7% per year after improvement countermeasures were emplaced. The air pollution control policy was especially more effective for coarse particulate matter (CPM, $PM_{10-2.5}$). The improvement of $NO_2$ pollution was generally very low, especially in cities which had considerable automobile traffic. The concentration of $SO_2$ pollution was rapidly improved in industrial areas, but did not show any difference for multiple and general cities. The predicted concentration of $PM_{10}$ for 2014 based on the trend over 2001-2009 was $53.4{\mu}g/m^3$, which fails to meet the target concentration of $40{\mu}g/m^3$. The predicted concentration of $NO_2$ shows a very low probability of achieving the target concentration of 22 ppb, and thus the current improvement of air quality has proven unsatisfactory. Conclusion: Air pollution control policy should be enforced according to regional pollution characteristics in order to obtain maximum effectiveness in improvement.

• 대한의용생체공학회:의공학회지
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• 제23권5호
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• pp.341-349
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• 2002

본 논문에서는 혈중 목표 농도 자동 조절기(Target-controlled infusion system. TCI)를 개발하는 것으로써, 마취의가 혈중 목표 농도를 설정하면 사용약제의 약동학적 모델링에 의해서 주입속도를 자동적으로 계산하여 마취의 깊이를 예측하는 약동학적 모델의 수립과 검증 방법을 설명한다. 정확한 약동학적 모델의 구축은 시스템의 성능에 큰 영향을 미치므로 먼저 PART 1에서는 약동학적 모델을 구축하되 3-콤파트먼트 모델과 4-콤파트먼트 모델로 해석하였다. 기존의 TCI에서 사용하고 있는 3-콤파트먼트 모델에 가상의 효과처 구획(Effect Site Compartment)을 만들고 이를 네 버내 구획으로 가정한 4-콤파트먼트 모델(Four-Compartment Model)을 수립하였고, matlab 5.0을 이용하여 비교 분석하였다. 모델은 혈중 목표 농도 주입(Plasma Targeting)과 효과처 목표 농도 주입(Effect Site Targeting), 혈중 농도 유지를 위한 주입율 계산과 기타 마취 상태를 추정하는 정보를 포함한다. 시뮬레이션의 결과를 바탕으로 4-콤파트먼트 모델을 디지털 z-변환을 거쳐 디지털시그널프로세서에 프로그램하고 TCI시스템의 적용가능성을 평가하였다. 정맥 마취용 TCI는 오동작에 대한 검증이 반드시 요구되므로 구축한 모델링에 대한 시뮬레이션의 평가 방법을 설정하였다. 기존의 TCI시스템과는 달리 약동학적 약물 전달 속도 상수(k-파라미터)를 독립적으로 조절할 수 있는 기능이 추가되어 다양한 약제의 사용이 가능할 뿐만 아니라 새로운 약동학적 모델의 개발과 평가에 기여하게 되고, 환자의 체형과 병명에 따른 약동학적 모델의 변화에 대응할 수 있게 하였다.

• 한국세라믹학회지
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• 제49권5호
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• pp.448-453
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• 2012

Nitrogen-incorporated $SnO_2$ thin films were deposited by rf magnetron sputtering. Comparative structural, electrical and optical studies of thin films deposited by sputtering of the Sn metallic target and sputtering of the $SnO_2$ ceramic target were conducted. The $SnO_2$ thin films deposited by sputtering of the Sn metallic target had a higher electrical conductivity due to a higher carrier concentration than those by sputtering of the $SnO_2$ ceramic target. Structurally the $SnO_2$ thin films deposited by sputtering of the $SnO_2$ ceramic target had a better crystallinity and a larger grain size. This study confirmed that there were distinct and clear differences in electrical, structural, and optical characteristics between $SnO_2$ thin films deposited by reactive sputtering of the Sn metallic target and by direct sputtering of the $SnO_2$ ceramic target.

• 한국물환경학회지
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• 제26권2호
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• pp.297-302
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• 2010

It is very important to know mean and confidence interval of water-quality constituents such as BOD for water-quality control and management of rivers and reservoirs effectively. The mean and confidence interval of BOD at Anseong2 and Hwangguji3 sampling stations which are located at the border of local governments in Anseong Stream were estimated and analyzed in this paper using Bootstrap technique which is one of non-parametric statistics. The results of Bootstrap were compared with arithmetic mean, geometric mean, Biweight method mean as a point estimator and distribution mean came from the appropriate probability distribution of Log-normal. In Bootstrap technique 12 data set was randomly selected in each year and 1000 samples was produced to get parameter of population. Visual Basic for Applications (VBA) of Microsoft Excel was utilized in Bootstrap. It was revealed that the Bootstrap technique can be used to explain more rigorously and robustly the achievement or violation of BOD target concentration in Total Maximum Daily Load (TMDL).

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.87-87
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• 2013

Sample concentration and purification processes are essential in the bio-analytical and pharmaceutical fields because most bio samples or media are extremely sophisticated. To concentrate and purify specific substances, passive membrane type filters have been utilized, which is driven by size or charge differences between target and others. The traditional and representative method to identify nucleic acid sequences in the complex biosample is gel electrophoresis, which has been worked by size and net charge of molecules. The adsorption phenomena have been also utilized to concentrate and purify biomolecules. This adsorption of biomolecule can be controlled under specific salts and surfaces as well as surface area. To utilize the differences of physical properties of molecules or bio-targets such as virus, bacteria, and cells, the nanotechnologies can be introduced in target concentration, purification, and isolation processes. In here, I'd like to briefly survey typical examples of nanobiotechnologies which are introduced in sample treatment. Also I specifically demonstrate two different simple techniques to concentrate and detect bacteria from the samples using multifunctional silica nanotube (SNT).

• Bulletin of the Korean Chemical Society
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• 제20권5호
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• pp.525-527
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• 1999

Many types of chemical data tend to be characterized by many measured variables on each of a few observations. In this situation, target concentration can be predicted using multivariate statistical modeling. However, it is necessary to use a few variables considering size and cost of instrumentation, for an example, for development of a portable biomedical instrument. This study presents, with a spectral data set of total hemoglobin in whole blood, the possibility that modeling using only a few variables can improve predictability compared to modeling using all of the variables. Predictability from the model using three wavelengths selected from all possible regression method was improved, compared to the model using whole spectra (whole spectra: SEP = 0.4 g/dL, 3-wavelengths: SEP=0.3 g/dL). It appears that the proper selection of variables can be more effective than using whole spectra for determining the hemoglobin concentration in whole blood.

• The Korean Journal of Pain
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• 제22권1호
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• pp.39-46
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• 2009

Background: Ketamine has an indirect sympathetic stimulation effect. We investigated heart rate variability (HRV) as a marker of cardiac autonomic function after a target controlled infusion (TCI) of ketamine with a plasma concentration of 30 or 60 ng/ml. Methods: In 20 adult volunteers, the mean of the R wave to the adjacent R wave interval (RRI), the range of RRI, the root mean square successive difference of intervals (RMSSD), the total power, the low frequency (LF, 0.04-0.15 Hz) power, the high frequency (HF, 0.15-0.4 Hz) power, the normal unit HF (nuHF), the normal unit LF (nuLF), the LF/HF ratio and the SD1 and the SD2 in the Poincare plot were measured before and after a TCI of ketamine. We observed for any psychedelic symptoms or sedation. Results: There were no differences in the mean and range of the RRI, RMSSD, total power, LF power, HF power, nuHF, nuLF, LF/HF ratio, SD1 and SD2 between before and after ketamine administration. The OAA/S score was higher and there were more psychedelic symptoms with a 60 ng/ml plasma concentration than with a 30 ng/ml plasma concentration. Conclusions: This study did not show any effect of a low plasma concentration of ketamine on the autonomic nervous system.

• 한국물환경학회지
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• 제31권3호
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• pp.286-294
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• 2015

Temporal and spatial characteristics of cyanobacterial communities at the monitoring stations for Harmful Algal Bloom Alert System (HABAS) in Nakdong River and Lake Dukdong were investigated for two years (2013 to 2014). A total of 30 cyanobacterial species from 14 genera were found at the survey stations. Microcystis sp. showed maximum cell density in the total cyanobacterial community in August, 2014 at ND-2 and in September, 2013 at ND-3 station. Lynbya limnetica and Geitlerinema sp., non-target species for alert criteria showed maximum cell density at ND-1 (August, 2013) and Dam station of Lake Dukdong (September, 2014), respectively. Total cyanobacterial cell density and the relative abundance of four target genera (Microcystis, Anabaena, Aphanizomenon and Oscillatoria spp.) for alert criteria was relatively lower in the mesotrophic Lake Dukdong than at the eutrophic riverine stations of Nakdong River, indicating cyanobacterial density and the RA of target genera is affected by the trophic state of the monitoring stations. Simulating the alert system using phycocyanin concentration as an alert criterion resulted in the longer period of alert issued compared to the period of alert issued using the current criterion of harmful cyanobacterial cell density due to the influence of phycocyanin concentration from non-target cyanobacterial species.