• Fashion & Textile Research Journal
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• v.1 no.2
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• pp.119-126
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• 1999

The purpose of this study was to serve as a basis for the creation of new design. For attaining the purpose, an investigation was made into the actual condition or problems of domestic and foreign fashion design, and fashion design information was acquired from the Internet. Then, taking the acquired information as the basic data for merchandising, an attempt was made to work out an outline by using the Corel-Trace program, a widely-used computer software, and to modify it by using the Corel-Draw program. The findings of this study were as below: 1) The informations provided by domestic home-pages were largely made up of fashion news and articles on the trend of fashion, but included few of picture report. Almost all of them weren't developed into a database by item or detail. The foreign fashion design web-site were numerous in number, providing diverse information. They offered not only moving images or picture report on fashion show, leading models, photo gallery or fashion trend, but up-dated data everyday. 2) A way to create a design to meet a designer's target is recommended in this study. At first, the fashion information acquired through computer network would be handled by the Corel-Trace program. After Bitmap image would be converted into Vector image, that would be modified by the Corel-Draw program to create a design to suit a designer's target.

• Archives of Pharmacal Research
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• v.29 no.7
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• pp.598-604
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• 2006

In many conventional drug delivery systems in vogue, failure to deliver efficient drug delivery at the target site/organs; is evident as a result, less efficacious pharmacological response is elicited. Microspheres can be derived a remedial measure which can improve site-specific drug delivery to a considerable extent. As an application, Lung-targeting Ofloxacin-loaded gelatin microspheres (GLOME) were prepared by water in oil emulsion method. The Central Composite Design (CCD) was used to optimize the process of preparation, the appearance and size distribution were examined by scanning electron microscopy, the aspects such as in vitro release characteristics, stability, drug loading, loading efficiency, pharmacokinetics and tissue distribution in albino mice were studied. The experimental results showed that the microspheres in the range of $0.32-22\;{\mu}m$. The drug loading and loading efficiency were 61.05 and 91.55% respectively. The in vitro release profile of the microspheres matched the korsmeyer’s peppas release pattern, and release at 1h was 42%, while for the original drug, ofloxacin under the same conditions 90.02% released in the first half an hour. After i.v. administration (15 min), the drug concentration of microspheres group in lung in albino mice was $1048\;{\mu}g/g$, while that of controlled group was $6.77\;{\mu}g/g$. GLOME found to release the drug to a maximum extent in the target tissue, lungs.

• International conference on construction engineering and project management
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• 2013.01a
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• pp.287-293
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• 2013

The annual expenditure on diesel oil and heavy oil in the construction sector is the second largest among all industrial sectors. According to the greenhouse reduction scheme of Korean Government, construction sector targeted 7.1% reduction by 2020. Although this target is not higher than other industrial sectors, it is not easy to achieve the reduction target without radical advance in technology, which cannot be expected to happen soon, considering the conservative characteristics of construction industry. Most researches on environmental issues focus on the issues related to energy saving matters during material production stage or maintenance stage, such as heating and insulation, and few deal with the issues directly related to the energy use in the construction sites. This research regards the operation of equipment for the on-site construction processes as a system and attempts to model the energy use processes related to the activities in construction sites, and provides simulation results of earth excavation and hauling processes. The result of this research is expected to aid construction planners estimating the time-based patterns of energy use and assessing greenhouse gas emission and to help selecting more energy efficient alternatives at the planning stage.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.50 no.4
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• pp.238-246
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• 2005

Rice yield and protein content have been shown to be highly variable across paddy fields. In order to characterize this spatial variability of rice within a field, two-year experiments were conducted in 2002 and 2003 in a large-scale rice field of $6,600m^2$ In year 2004, an experiment was conducted to know if variable rate treatment (VRT) of N fertilizer, that was prescribed for site-specific management at panicle initiation stage, could reduce spatial variation in yield and protein content of rice while increasing yield compared to conventional uniform N topdressing (UN, 33kg N/ha at PIS) method. VRT nitrogen prescription for each grid was calculated based on the nitrogen (N) uptake (from panicle initiation to harvest) required for target rice protein content of $6.8\%$, natural soil N supply, and recovery of top-dressed N fertilizer. The required N uptake for target rice protein content was calculated from the equations to predict rice yield and protein content from plant growth parameters at panicle initiation stage (PIS) and N uptake from PIS to harvest. This model· equations were developed from the data obtained from the previous two-year experiments. The plant growth parameters for the calculation of the required N were predicted non-destructively by canopy reflectance measurement. Soil N supply for each grid was obtained from the experiment of year 2003, and N recovery was assumed to be $60\%$ according to the previous reports. The prescribed VRT N ranged from 0 to 110kg N/ha with an average of 57kg/ha that was higher than 33 kg/ha of UN. The results showed that VRT application successfully worked not only to reduce spatial variability of rice yield and protein content but also to increase rough rice yield by 960kg/ha. The coefficient of variation (CV) for rice yield and protein content was reduced significantly to $8.1\%$ and $7.1\%$ in VRT from $14.6\%$ and $13.0\%$ in UN, respectively. And also the average protein content of milled rice in VRT showed very similar value of target protein content of $6.8\%$. In conclusion the procedure used in this paper was believed to be reliable and promising method for reducing within-field spatial variability of rice yield and protein content. However, inexpensive, reliable, and fast estimation methods of natural N supply and plant growth and nutrition status should be prepared before this method could be practically used for site-specific crop management in large-scale rice field.

• Journal of the Korean Chemical Society
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• v.57 no.4
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• pp.493-498
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• 2013

Liposomes, which can deliver payload at target site, have been studied as drug carrier. However, conventional liposomes have limitation for drug release at target site. Therefore, we developed hydroxyapatite (HA) coated ultrasound sensitive liposomes to increase drug release at target site and to enhance stability in blood stream. Control liposome was prepared using hydrogenated soy phosphatidylcholine (HSPC) and cholesterol, and then we assessed HA coating on the surface of control liposomes using calcium acetate, phosphoric acid, and 25% ammonium solution. Doxorubicin was used as a model drug. Size of HA coated liposomes was 120 nm and encapsulation efficiency of doxorubicin in liposomes was up to 95%. Size of HA coated liposomes are not changed in 30% serum solution, however, the control liposomes was 1.4 fold increased. After ultrasound triggered drug release from liposomes, intracellular efficiency of drug released from HA coated liposomes was 3 fold increased compared to control liposomes. In this study, we developed ultrasound sensitive liposomes to enhance drug release, which will be applied in controlled drug release at disease site.

• World Technopolis Review
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• v.1 no.3
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• pp.206-225
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• 2012

The development of the Surrey Research Park by the University of Surrey is an addition to a number of existing strategies to collaborate with industry that it has developed over its 120 year history. The potential to undertake this development was based on owning a substantial land holding that the University acquired when the Borough Council for the town of Guildford invited the University to relocate from Battersea in London to its new location in 1966. Initial plans for the Park in 1979 were accelerated in 1981 in response to plans by the then government to reduce funding for Higher Education in the UK. Beyond a broad master plan for the site that was based on topography and access to the site the plans that were developed were based on a survey of 100 companies that were deemed to be in the target market for the site and a review of the other 7 science parks that were being developed in the UK in 1981. The findings from this proved to be important in developing the master plan for the site. Another important influence on the project was the objectives that were defined for the 3 stakeholders in the project of the University, the tenant companies and the planning authority relate to economic development, a competitive advantage of tenant companies, knowledge transfer, the profile for the University and the capacity to generate income proved to be a valuable framework on which to develop a master plan. These details were underpinned by five objectives which served the three stakeholders in the site. Those for the University included commercial potential, knowledge transfer and image and reputation; those for the town primarily related to economic development and the plan was to help tenants gain a competitive advantage by locating on the site. In addition a number of success indicators were defined for the project against which to measure performance and have remained as a useful set of parameters on which to base the assessment of the performance of the site. In combination with these indicators a further analysis deals with the success factors that are considered as important in influencing performance. The paper sets details the history of the park and covers the success indicators and factors and reviews these in the context of the original objectives for the site.

• Cross-Cultural Studies
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• v.23
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• pp.191-214
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• 2011

Today the company's brand sites are in tendency locating as a handy method to administrate company vision, value and image. So this study tried to examine the aspects of storytelling around Amore Pacific's brand site. To secure the discussion's centrality and concreteness, two issues are considered to be aimed in methodology. First, the menus of relevant site were examined to see if they are securing minimal narrative. This was an attempt to discuss the minimum narrativity that target text is supposed to possess, to objectify little more the term 'storytelling.' After considering the menus of relevant site through narratological ideas of Gerald Prince, the menus that satisfy the level of minimum narrative were hardly seen. Even 'OUR STORY', showing the intention of unraveling the vision and values within the company brand by stories, is not seemed to be reaching universal, objective storytelling. Second, pragmatic, reception theory were applied as another standard to judge storytelling possibilities of Amore Pacific's brand site. Roger C. Schank's script theory, being considered in the field of cognitive linguistics and cognitive psychology, became a handy tool for examining the interactions and its meaning between brand sites and its visitors. As a result, the relevant site could be seen as attempting storytelling following time sequence, through narrator kindly explaining 'visual image-event.' And it was conjecturable that, because of such function of narrator, visitors finishes storytelling in a personal shape by operating internal story based script. This study examined the level and methods of storytelling limited in online environment called as company brand site. But more studies are needed to be in progress, such as about the ways for company websites or brand sites to have an effective, continuous influence on potential consumers, narrator set-up ways suitable for character of subordinate menus, organizations of minimum narrative and so on.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1408-1413
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• 2005

Elevated expression of carcinoembryonic antigen (CEA) has been implicated in various biological aspects of neoplasia such as tumor cell adhesion, metastasis, blocking of cellular immune mechanisms, and antiapoptosis function. Thus, the CEA could be an important target for anticancer therapy. In this study, we developed Tetrahymena group 1 intron-based trans-splicing ribozymes that can specifically target and replace CEA RNA. To this end, we first determined which regions of the CEA RNA were accessible to ribozymes by employing an RNA mapping strategy that was based on a trans-splicing ribozyme library. Next, we assessed the ribozyme activities by comparing the trans-splicing activities of several ribozymes that targeted different regions of the CEA RNA, and then the ribozyme that could target the most accessible site was observed to be the most active with high fidelity in vitro. Moreover, the specific trans-splicing ribozyme was found to react with and altered the target CEA transcripts in mammalian cells with high fidelity. These results suggest that the Tetrahymena ribozyme can be utilized to replace CEA RNAs in tumors with a new RNA-harboring anticancer activity, thereby hopefully reverting the malignant phenotype.

• Journal of Environmental Science International
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• v.19 no.1
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• pp.47-59
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• 2010

This study was to examine the characteristics of wirdbirds habitat for improvement plan in green corridor. The target site, Gangseo-gu artificial green corridor was set up with the structure in which small scale of core green space with Goongsan and Yeomchang neighborhood parks in urbanized city was connected with the artificial green space with Gongamnaru, Hwanggeumnae neighborhood parks with 28~42.5 m in width. Wild birds six~eleven species; Dendrocopos spp, Paradoxornis webbiana, Parus major, Phasianus colchicus, etc. were observed in core green, but wild birds of two~five species: Columba livuia, Passer montanus, Pica pica, Hypsipetes amaurotis, etc. were observed in artificial green space. Thus wild birds of artificial and generalist species only moved in artificial green space. The artificial green space where vegetation structure was consisted of single-layer with poorness chose target species laying stress on generalist species and edge species of Parus major, P. palustris, Paradoxornis webbiana etc. for short-term and interior species of Dendrocopos major, Picus canus, etc. for long-term. The result suggested enhancement methods for target species's habitat in green corridor: to secure at least a corridor 30 meters in artificial corridor, to secure ecological pond, to offer the various shelterer and environment of prey-resources through the multi-layer structure.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.3
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• pp.405-413
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• 2011

Defense Systems Test Center in ADD supports increasingly various missile test requirements such as higher altitude event, multi target operation and low-altitude, high velocity target tracking. In this paper, we have proposed the development of instrumentation radar tracking status simulator based on virtual reality. This simulator can predict the tracking status and risk of failure using several modeling algorithms. It consists of target model, radar model, environment model and several algorithms includes the multipath interference effects. Simulation results show that the predict tracking status and signal are similar to the test results of the live flight test. This simulator predicts and analyze all of the status and critical parameters such as the optimal site location, servo response, optimal flight trajectory, LOS(Line of Sight). This simulator provides the mission plan with a powerful M&S tool to rehearse and analyze instrumentation tracking radar measurement plan for live flight test at DSTC(Defense Systems Test Center).