• Journal of Nutrition and Health
• /
• 제45권6호
• /
• pp.552-561
• /
• 2012

Metabolic syndrome is a cluster of metabolic risk factors associated with increased risk of cardiovascular diseases. Recently, the prevalence of metabolic syndrome has increased in Korea. The aim of this study was to develop a Healthy Han-sik Nutrition Education Program (HHNEP) based on commonly recognized Korean foods in order to decrease metabolic syndrome risks. The target population of the HHNEP is adults with metabolic risk factors. The initial version of the HHNEP was developed based on a review of literature and various dietary guidelines by expert committees as well as the results of a survey on the perception of common Korean dishes and foods as Han-sik. The focus group discussion conducted of nine participants from the target population. After minor modification, the final version was developed. The contents included five sections: 1) aims, 2) introduction of Korean Food Guidance System, 3) cholesterol contents in food, 4) menu planning method using Han-sik, and 5) examples of daily Han-sik menu. The Han-sik list was selected based on the results from a Han-sik perception answered by 35 Korean adults aged 30-60 years using 517 frequently consumed Korean foods from the fourth Korea National Health and Nutrition Examination Survey. The nutrition education program was developed based on scientific evidence for the prevention of metabolic syndrome and focuses on tailoring education to an individual's dietary problems. Educational method was developed by a group of expert committees based in planned behavior theory and related research results. The education method consisted of assessment of current diet, four face-to-face nutrition education sessions over 8 weeks, and evaluation after 8 and 16 weeks. Initial version of nutrition education materials and methods was tested for feasibility by a select group of nine Korean healthy adults. Successful implementation of the program would include application by nutritional professionals at the health promotion center of the hospitals, public health center, and work sites. Intervention studies are needed to evaluate the feasibility and effectiveness of this program before large-scale applications.

• 한국정보과학회논문지:소프트웨어및응용
• /
• 제31권6호
• /
• pp.716-727
• /
• 2004

컴포넌트 기반 소프트웨어 개발 (CBD) 기술은 재사용 가능한 컴포넌트를 조합하여 효율적으로 소프트웨어를 개발함으로써 개발 노력과 상품화 시간을 줄여주는 새로운 기술로 정착되고 있다. 이러한 CBD 컴포넌트는 한 도메인의 표준이나 공통적인 기능을 제공하여야 재사용성이 높아진다. 특히, 공통성 안의 미세한 가변적인 부분도 모델링하고, 이 가변성을 각 어플리케이션의 특성에 적합하게 특화 할 수 있도록 설계되어야 한다. 기존의 CBD 방법론에서도 이 중요성이 강조되고 있지만, 체계적이며 구체적인 개발 프로세스, 적용 지침 및 산출물 양식의 제공이 미흡하여, 도메인 컴포넌트의 개발은 비체계적인 프로세스와 개발자의 경험에 의존해 왔다. 본 논문은 컴포넌트 설계를 위한 체계적인 프로세스와 기법을 제안한다. 이 프로세스는 여러 단계와 활동으로 구성되며, 각 활동에 대한 세부 지침과 표준 양식도 포함하여 보다 효과적인 컴포넌트 개발을 도모한다. 제안된 기법의 실효성 검증을 위하여 금융 도메인에 적용한 사례연구를 제시하며, 다른 기법들과의 비교 평가도 다룬다. CBD의 공통 컴포넌트 개발에 제안된 프로세스와 지침의 사용함으로써 보다 재사용성과 적용성이 높은 컴포넌트가 비용 및 시간에 있어서 효율적으로 개발될 것으로 기대된다.

• 한국산학기술학회논문지
• /
• 제19권10호
• /
• pp.89-100
• /
• 2018

방위력개선사업의 선행연구는 소요가 결정된 무기체계의 효율적 획득방법 결정을 지원하기 위해 수행되는 사업단계로, 선행연구단계에서 수행되어야할 요소를 식별하기 위해 안전분석 과정에서 활용되는 FTA/FMEA 기법의 수행방안을 착안 및 테일러링을 통해 핵심검토 항목 도출을 위한 방법론을 제시하였었다. 기존의 연구에서 도출한 핵심요소를 보완하기 위해 핵심요소로부터 발생 가능한 다양한 사건들을 추가 보완 및 분석이 필요했으며 이를 위해 타 산업분야에서 안전분석을 위해 수행하는 HAZOP 기법을 활용하여 핵심요소 도출결과를 보완하였다. HAZOP/FTA/FMEA 기법을 연계하여 도출된 선행연구단계의 핵심요소에 대해 입 출력 정보 및 연관관계를 설정하여 수행절차를 분석하고 모델화하였다. 또한 선행연구 수행성과에 대해 수행성숙도를 평가하고 성숙도가 낮은 핵심요소에 대해 관련 핵심요소와의 연동정보를 바탕으로 위험도 기반 대응 매뉴얼을 생성하였다. 본 연구결과를 토대로 방위력개선사업 선행연구단계에서 핵심요소 및 수행절차, 위험관리 대응 매뉴얼 적용을 통해 사업추진간 성능 비용 일정을 충족하고 예상되는 위험을 감소시켜 효율적이고 안정적인 방위력개서사업 추진을 기대할 수 있다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제25권7호
• /
• pp.1021-1028
• /
• 2012

Peripheral blood mononuclear cells (PBMCs) discriminate microbial pathogens and induce T-cell responses of appropriate effector phenotype accordingly. Toll-like receptors (TLRs), in part, mediate this microbial recognition and differentiation while the development of T-cell effector functions critically depends on the release of Th1- or Th2- type cytokines. In the present study, buffalo PBMCs were stimulated under in vitro culture conditions by Bacillus subtilis cell wall petidoglycan, a TLR2 ligand, in a dose- and time- dependent manner. The expression of TLR2 as well as the subsequent differential induction of the Th1 and Th2 type cytokines was measured. Stimulation was analyzed across five doses of peptidoglycan ($10{\mu}g/ml$, $20{\mu}g/ml$, $30{\mu}g/ml$, $40{\mu}g/ml$ and $50{\mu}g/ml$) for 3 h, 12 h, 24 h and 36 h incubation periods. We observed the induction of TLR2 expression in a dose- and time-dependent manner and the peptidoglycan induced tolerance beyond $30{\mu}g/ml$ dose at all incubation periods. The correlation between peptidoglycan stimulation and TLR2 induction was found positive at all doses and for all incubation periods. Increased production of all the cytokines was observed at low doses for 3 h incubation, but the expression of IL-4 was relatively higher than IL-12 at the higher antigen doses, indicating tailoring towards Th2 response. At 12 h incubation, there was a pronounced decrease in IL-4 and IL-10 expression relative to IL-12 in a dose- dependent manner, indicating skewing to Th1 polarization. The expression of IL-12 was highest for all doses across all the incubation intervals at 24 h incubation, indicating Th1 polarization. The relative expression of TNF-${\alpha}$ and IFN-${\gamma}$ was also higher while that of IL-4 and IL-10 showed a decrease. For 36 h incubation, at low doses, relative increase in the expression of IL-4 and IL-10 was observed which decreased at higher doses, as did the expression of all other cytokines. The exhaustion of cytokine production at 36 h indicated that PBMCs became refractory to further stimulation. It can be concluded from this study that the cytokine response to sPGN initially was of Th2 type which skews, more pronouncedly, to Th1 type with time till the cells become refractory to further stimulation.

• 정보처리학회논문지D
• /
• 제11D권5호
• /
• pp.1105-1122
• /
• 2004

소프트웨어 품질 개선과 관련된 조직 및 기업들의 노력들은 소프트웨어 생산성과 품질을 어느 정도 향상시켰지만 근본적인 해결 방안이 되지 못하여왔다 이와 같은 결과는 인력과 기술보다는 프로세스의 제도화의 부족에서 기인한다(1). 최근에는 프로세스 또는 작업 산출물이 명시된 요구사항과 계획, 표준을 따르게 하여 프로세스와 산출물을 가시적으로 관리하는 프로세스 품질보증을 통한 품질의 향상을 시도하는 움직임이 활성화되고 있으며, 이와 관련된 표준들과 모델들이 제시되고 있다. 하지만 관련 표준들과 모델들에서 제시된 내용은 추상적이며, 이를 적용하는데 필요한 세부적인 절차나 방법, 관련 산출물 등에 대해 기술하고 있지 않다. 따라서 표준 및 모델에서 제시하는 내용을 도입하고자 하는 조직들은 관련 표준의 전체 구조 및 내용을 숙지하고 받아들이기 위한 긴 노력과 많은 공수를 들여야만 품질에 대한 해당 조직의 목적 및 목표를 충족시킬 수 있는 소프트웨어 품질보증 활동 프로세스를 확립할 수 있다. 이에 본 연구에서는 조직들이 보다 편리한 방법으로 체계적이고 견고한 품질 보증 활동 프로세스를 구축할 수 있도록 지원하기 위한 패키지를 개발하였다. 본 연구에서 개발 된 패키지는 CMM/CMMI, ISO15504, ISO12207등의 관련 표준에서 기술하고 있는 품질보증 활동과 소프트웨어 프로세스 전 주기에 대한 내용의 분석, 기존연구의 분석 및 구조화, Best Practice 평가 및 분석의 과정을 통해 소프트웨어 품질보증 활동을 체계적이고 구조적으로 지원할 수 있는 소프트웨어 품질보증 지원 패키지이다. 개발된 패키지를 활용하면, 조직들은 조직의 여건 및 특성, 그리고 프로젝트의 성격에 맞도록 필요한 조정만을 통하여 품질보증 프로세스를 확립할 수 있다. 개발 된 패키지의 효율적인 활용이 내조직의 소프트웨어 품질보증 구축에 투입되는 공수 및 어려움을 줄일 것으로 기대된다.

• Journal of Gastric Cancer
• /
• 제13권3호
• /
• pp.149-156
• /
• 2013

Purpose: Clinical stage of gastric cancer is currently assessed by computed tomography. Accurate clinical staging is important for the tailoring of therapy. This study evaluated the accuracy of clinical N staging using stomach protocol computed tomography. Materials and Methods: Between March 2004 and November 2012, 171 patients with gastric cancer underwent preoperative stomach protocol computed tomography (Jeju National University Hospital; Jeju, Korea). Their demographic and clinical characteristics were reviewed retrospectively. Two radiologists evaluated cN staging using axial and coronal computed tomography images, and cN stage was matched with pathologic results. The diagnostic accuracy of stomach protocol computed tomography for clinical N staging and clinical characteristics associated with diagnostic accuracy were evaluated. Results: The overall accuracy of stomach protocol computed tomography for cN staging was 63.2%. Computed tomography images of slice thickness 3.0 mm had a sensitivity of 60.0%; a specificity of 89.6%; an accuracy of 78.4%; and a positive predictive value of 78.0% in detecting lymph node metastases. Underestimation of cN stage was associated with larger tumor size (P<0.001), undifferentiated type (P=0.003), diffuse type (P=0.020), more advanced pathologic stage (P<0.001), and larger numbers of harvested and metastatic lymph nodes (P<0.001 each). Tumor differentiation was an independent factor affecting underestimation by computed tomography (P=0.045). Conclusions: Computed tomography with a size criterion of 8 mm is highly specific but relatively insensitive in detecting nodal metastases. Physicians should keep in mind that computed tomography may not be an appropriate tool to detect nodal metastases for choosing appropriate treatment.

• 대한두경부종양학회지
• /
• 제20권2호
• /
• pp.177-180
• /
• 2004

Objectives: To completely excise a malignant tumor which invades carotid artery walls, the resection and reconstruction of the carotid artery is essentially required. In most of the cases, interposition graft using a saphenous vein has been performed, however the vessel caliber discrepancy between a common carotid artery and the saphenous vein can result in a problem on surgical technique. We have introduced and evaluated a new titanium hemoclip tailing method to overcome vessel caliber discrepancy in interposition saphenous vein graft for carotid artery resection in the treatment of head and neck cancers. Method: After carotid artery resection, the calibers of the proximal common carotid artery and the vein were compared, and an orifice of the common carotid artery was gradually reduced to a little larger than or the same size as the orifice of the vein by using the titanium hemostatic clip. Subsequently, the common carotid artery was connected to the vein through anastomosis. The same method was also applied to the distal anastomosis site. There after, the vessels were connected through the anastomosis, and a circulation was restored by releasing a vascular clamp. Then, a titanium hemostatic clip-applied redundant portion on the outside of carotid artery was sutured by the blanket edge suture method, using 6-0 Prolene. Results: We have experienced this method in two patients with recurrent squamous cell carcinoma and neuroblostoma, respectively. The interposition saphenous vein graft of these patients was found to maintain good patency on the follow up angiography after one year, and they had no specific vascular complication, such as atherosclerosis. Conclusion: This method made it possible to simply perform the interposition saphenous vein graft (ISVG) within a short time and, therefore, was very useful for shortening the duration to block circulation.

• 복식
• /
• 제58권2호
• /
• pp.78-92
• /
• 2008

The mutual relationship between fashion and architecture and the similarities in their form and structure have been continuously debated over the decades, considering that both spheres are objects used in human life. Both spheres bring about the creation of three-dimensional space structures that are completed by the human body and material, based on a design targeted for people. The similarities between fashion and architecture in terms of form and structure have been debated by western architecture scholars focusing on the support that holds the garment's shape, the tailoring of a men's suit and also the material. The debate originates from the discussion of F. Th. Vischer, Kritische Gnge, and Gottfried Semper during the nineteenth century on the similarities between crinoline and the form of architecture and also the similarities between sewing and architecture. However, architects always regarded fashion as the inferior creative process that follows architecture in viewing the relationship between fashion and architecture. During the mid to end of the twentieth century, contrary to previous decades, the sense of fashion in architecture stood out, as an issue and a different approach was taken in discussing architecture that incorporates fashion. Accordingly, in the mid 1990's, architecture scholars such as Deborah Fausch and Mark Wigley began to conduct close observation of the mutual relationship between fashion and architecture from a more equal point of view. Notwithstanding, their point of view was still biased towards architectural standards. Commencing the Millennium, fashion has become the primary work of creation which leads style in all spheres, and under these circumstances this point of view has transferred from architecture to fashion when thinking about relationships between these spheres. The discussion on fashion and architecture form fashion's point of view is currently concentrated on the post 1990's phenomenon and illustrates the environment that is related to architecture. In general, the discussion is limited to determining a work of an individual designer as 'being architectural' when explaining the sculptural form of fashion. Therefore, this research aims to renew the discussion on twentieth century fashion design, which was neglected in any studies on observing architecture and fashion. The aim of this research is to classify the architectural paradigm of twentieth century fashion design and to observe the architectural forms of the respective eras. It is necessary to have a close observation of the architectural paradigm in twentieth century fashion design where support tools such as the crinoline was avoided and the form and functionality of the garment itself was emphasized. I will conduct this research by considering the architectural form shown in fashion as a practical three-dimensional creation that exists in space.

• 한국산학기술학회논문지
• /
• 제18권12호
• /
• pp.286-299
• /
• 2017

국내 공연예술은 공급과잉과 유통영역의 부재, 뚜렷하지 않은 비즈니스 모델 등으로 인한 침체기를 맞고 있다. 이러한 어려움을 타개하기 위해서는 무엇보다 객관적으로 제공되는 시장데이터를 활용해 마케팅의 효율성과 정확도를 높임으로써 관객개발과 충성도 확보가 필요한 시점이다. 본 연구는 이를 해결하기 위한 대안 중 하나가 보다 보편적이고 정확한 통계와 공연별 맞춤형 서비스 제공이 가능한 '빅데이터' 분석이라는 관점에서 시작되었다. 먼저 빅데이터의 특징과 분석기술, 그리고 공연예술 소비자 분석에 대한 이론적 배경과 함께 한 신용카드사가 실시한 빅데이터 분석사례를 살펴보았다. 이를 통해 빅데이터에 의한 공연예술 소비자 연구의 의미와 한계, 그리고 그러한 한계들을 극복하기 위한 대안을 제시하고자 하였다. 사례분석 결과, 공연 구매자 대상의 카드사 데이터 자체의 불완전성, 기존 이론 검증의 한계, 낮은 활용도, 소비자 성향 및 구매 동인 분석의 한계 등이 도출되었다. 또한 이러한 문제점을 극복하기 위한 대안으로 장르와 공연명 파악이 가능하고 성향이나 구매요인 등을 추출해낼 수 있는 예매처 정보, 설문조사와의 결합과 소셜 데이터와의 매쉬업을 통해 구매동기 등의 정성적 분석을 그 대안으로 제시하였다. 이 연구는 궁극적으로는 공연예술 소비자에 대한 연구가 빅데이터 시대에 어떠한 방향으로 이루어져야하며, 어떤 변화를 모색해야 할 것인가에 대한 고민의 시작점이라고 할 수 있다. 이러한 연구결과를 바탕으로 공연예술 관객개발을 위한 보다 구체화된 정성적 분석 사례들이 많이 출현하기를 기대하며, 지금의 공연예술시장의 흐름을 정확하게 대변해 주는 빅데이터 분석과 가공을 위한 솔루션들이 계속 개발되기를 바란다.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2011년도 제41회 하계 정기 학술대회 초록집
• /
• pp.146-147
• /
• 2011

Processing a large area substrate for liquid crystal display (LCD) or solar panel applications in a capacitively coupled plasma (CCP) reactor is becoming increasingly challenging because of the size of the substrate size is no longer negligible compared to the wavelength of the applied radio frequency (RF) power. The situation is even worse when the driving frequency is increased to the Very High Frequency (VHF) range. When the substrate size is still smaller than 1/8 of the wavelength, one can obtain reasonably uniform process results by utilizing with methods such as tailoring the precursor gas distribution by adjustingthrough shower head hole distribution or hole size modification, locally adjusting the distance between the substrate and the electrode, and shaping shower head holes to modulate the hollow cathode effect modifying theand plasma density distribution by shaping shower head holes to adjust the follow cathode effect. At higher frequencies, such as 40 MHz for Gen 8.5 (2.2 m${\times}$2.6 m substrate), these methods are not effective, because the substrate is large enough that first node of the standing wave appears within the substrate. In such a case, the plasma discharge cannot be sustained at the node and results in an extremely non-uniform process. At Applied Materials, we have studied several methods of modifying the standing wave pattern to adjusting improve process non-uniformity for a Gen 8.5 size CCP reactor operating in the VHF range. First, we used magnetic materials (ferrite) to modify wave propagation. We placed ferrite blocks along two opposing edges of the powered electrode. This changes the boundary condition for electro-magnetic waves, and as a result, the standing wave pattern is significantly stretched towards the ferrite lined edges. In conjunction with a phase modulation technique, we have seen improvement in process uniformity. Another method involves feeding 40 MHz from four feed points near the four corners of the electrode. The phase between each feed points are dynamically adjusted to modify the resulting interference pattern, which in turn modulate the plasma distribution in time and affect the process uniformity. We achieved process uniformity of <20% with this method. A third method involves using two frequencies. In this case 40 MHz is used in a supplementary manner to improve the performance of 13 MHz process. Even at 13 MHz, the RF electric field falls off around the corners and edges on a Gen 8.5 substrate. Although, the conventional methods mentioned above improve the uniformity, they have limitations, and they cannot compensate especially as the applied power is increased, which causes the wavelength becomes shorter. 40 MHz is used to overcome such limitations. 13 MHz is applied at the center, and 40 MHz at the four corners. By modulating the interference between the signals from the four feed points, we found that 40 MHz power is preferentially channeled towards the edges and corners. We will discuss an innovative method of controlling 40 MHz to achieve this effect.