• 한국추진공학회:학술대회논문집
• /
• 한국추진공학회 2003년도 제21회 추계학술대회 논문집
• /
• pp.1-5
• /
• 2003

This paper deals with dynamic instability of slender rocket-propelled flying bodies, such as launch vehicle and advances missiles subjected to aerodynamic loads and an end rocket thrust. A flying body is simplified into a uniform free-free beam subjected to an end follower thrust. Two types of aerodynamic loads are assumed in the stability analysis. Firstly, it is assumed that two concentrated aerodynamic loads act on the flying body at its nose and tail. Secondly, to take account of effect of unsteady flow due to motion of a flexible flying body, aerodynamic load is estimated by the slender body approximation. Extended Hamilton's principle is applied to the considered beam for deriving the equation of motion. Application of FEM yields standardeigen-value problem. Dynamic stability of the beam is determined by the sign of the real part of the complex eigen-values. If aerodynamic loads are concentrated loads that act on the flying body at its nose and tail, the flutter thrust decreases by about 10% in comparison with the flutter thrust of free-free beam subjected only to an end follower thrust. If aerodynamic loads are distributed along the longitudinal axis of the flying body, the flutter thrust decreases by about 70% in comparison with the flutter thrust of free-free beam under an end follower thrust. It is found that the flutter thrust is reduced considerably if the aerodynamic loads are taken into account in addition to an end rocket thrust in the stability analysis of slender rocket-propelled flying bodies.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2010년 춘계학술대회논문집
• /
• pp.195-200
• /
• 2010

Numerical investigation was conducted to study the effects of after-body configurations and nozzle lip on the PIFS(Plume Induced Flow Separation) and eat flux to the base face. Two dimensional and axi-symmetric non-equilibrium Navier-Stoke's solver with $k-{\omega}$ SST turbulence model was used to solve the launching vehicle type configuration with propulsive jet. The experimental result of Robert J. McGhee was compared with our computational results for code validation. Three types of the after-body configurations (Straight, Boat-tail, Flare type) were simulated for this study. And the nozzle lip effect was studies using the three types of base configurations same simulation conditions. As a result of numerical investigations, higher pressure ratio condition and boat-tail after-body configuration caused severe PIFS phenomenon but the flare type after-body configuration and low pressure ratio suppressed PIFS. Flare type after-body configuration and low pressure ratio case reduced heat flux to base face. The nozzle lip dispersed the heat flux widely along the base face and the nozzle lip.

• Asian-Australasian Journal of Animal Sciences
• /
• 제13권4호
• /
• pp.440-445
• /
• 2000

Thirty lactating Javanese thin-tail ewes (12 ewes had been injected, prior to mating, with 700 IU pregnant mare serum gonadotropin, and 18 ewes with saline as a control) were used to evaluate the effect of superovulation on milk production during lactation and mammary chemical indices at the end of lactation. Thirteen ewes (9 control and 4 superovulated ewes) were fed at low and the other 17 ewes (9 control and 8 superovulated ewes) were fed at high quality ration. Superovulated ewes, either fed at low or high quality ration, had dramatically higher milk yields (57%). At the end of lactation, superovulated ewes had higher mammary dry fat-free tissue, mammary DNA concentration, total mammary DNA and RNA contents than nonsuperovulated ewes. Superovulation did not affect mammary RNA and collagen concentrations, and total collagen content. Ration quality did not significantly increase milk production during lactation and mammary chemical indices at the end of lactation. The observed increase in milk production in the superovulated ewes was probably due to the increased mammary secretory cell number and their synthetic activities during lactation as a result of the increased endogenous hormonal stimulation of mammary growth and development during pregnancy.

• Journal of Ginseng Research
• /
• 제15권1호
• /
• pp.6-12
• /
• 1991

The analgesic effect of morphine was antagonized in mice pretreated with ginseng total saponin intraperitoneally, intracerebrally and intrathecally. The antagonized effects of morphine analgesia were reversed predominantly by treatment with L-3, 4-dihydroxyphenylalanine in the tail pinch test and 5-hydroxytryptophan in the tail flick test respectively. These indicate that the antagonistic action of ginseng total saponin might be due to their inhibitions of the activation of descending ihibitory systems at the cerebral site as well as spinal. In addition, any appreciable changes of brain biogenic monoamine levels were not observed in mice pretreated with ginseng total saponin at various time intervals. These results obtained suggest that a newly equilibrated state of neurologic function could be found in mice pretreated with ginseng total saponin, and modification of neurologic function in the mechanism for the antagonism of morphine analgesia by ginseng total saponin was more important than the changes of brain biogenic monoamine levels.

• Preventive Nutrition and Food Science
• /
• 제21권4호
• /
• pp.373-377
• /
• 2016

Menopausal hot flushes (HFs), which manifest as a transient increase in skin temperature, occur most frequently in postmenopausal women, and sometimes negatively influence daily life. We investigated the effect of an aqueous extract of Cynanchum wilfordii (CWW) in a rat model of menopausal HFs, where tail skin temperature (TST) is increased after the rapid estrogen decline induced by ovariectomy. Ten-week-old female rats were ovariectomized and treated with CWW for 1 week. We measured TST and rectal temperatures (RT) and investigated serum estradiol. The TST in ovariectomized (OVX) rats was significantly elevated after ovariectomy compared with control rats, whereas the RT in OVX rats was not elevated. Administration of CWW (200 mg/kg/d for 7 days, p.o.) significantly improved the skin temperature increase in OVX rats. The lower level of serum estradiol in OVX rats was significantly increased by supplying E2, but it was not affected by CWW. The present study indicates a need for future research involving treatment with high concentrations of C. wilfordii and measurement over 24 h.

• Asian-Australasian Journal of Animal Sciences
• /
• 제6권1호
• /
• pp.79-86
• /
• 1993

Twelve docked and 12 intact Najdi lambs of equal numbers of males and females were slaughtered at 40 kg shorn shrunk body weight, Lipid in all empty body fat components; namely, subcutaneous, intermuscular, intramuscular, omental, mesenteric, channel, perirenal, pericardial, tail, viscera, bone and hide, were determined. Except for ram lambs, which had a lower percentage of lipid in intermuscular partition in loin cut, sex did not influence the relative proportion of subcutaneous or intermuscular fat in each wholesale cut. The data also showed that docking did not change the distribution of lipid in intermuscular and intramuscular fat partitions in each wholesale cut. Docked lambs tended to accumulate lower proportions of the lipid in subcutaneous fat component in the cuts located along the dorsal line than intact lambs. The total amount of lipid deposited in the empty body of ewe lamb was heavier in weight than that of ram lamb. Docking had no effect on the distribution of total lipid in the empty body, except for subcutaneous fat component, being greater in docked lambs than did intact ones. Generally, the highest proportion of fat was associated with subcutaneous depot followed, in order, by intermuscular, mesenteric, tail, intramuscular and omental fat partitions.

• 한국방사성폐기물학회:학술대회논문집
• /
• 한국방사성폐기물학회 2005년도 춘계 학술대회
• /
• pp.513-517
• /
• 2005

This study examined the possibility of using striped field mice as a biological dosimeter or indicator for the environmental radio-surveillance. For this study, the external morphological characteristics and isoenzymic types of dark-striped field mice were studied after they were captured. Among the morphological external characteristics, the dark-brown coat, dark back stripe, head-to-tail length, tail length, and ear length matched the taxonomical characteristics of dark-striped field mice. The analyses on L-lactate dehydrogenase, aspartate aminotransferase, and malate dehydrogenese revealed that one species of dark-striped field mice, called Apodemus agrarius, was inhabitated throughout a wide range of Korea. On the other hand, A. agrarius and ICR mice to analyze their survival rate and frequency of micronuclei in peripheral polychromatic erythrocytes after irradiation (0, 0.5, 1, 3, 5, 7, 9 Gy). The $LD_{50/30}$ of A. agrarius and ICR mice were approximately 5 Gy and 7Gy, respectively. The results of the study reveal that wild A. agrarius have a high potential as a biological monitoring system to determine the impact of radiation effect in areas such as those within the vicinity of nuclear power plants.

• Steel and Composite Structures
• /
• 제48권5호
• /
• pp.507-530
• /
• 2023

The number of studies investigating the response of concrete-filled tubes (CFTs) under shear has been very limited in the literature. This lack of research has been traditionally reflected in international design standards as rather conservative shear strength predictions for CFTs. The dearth of research on the shear response is even more pronounced for the case of concrete-filled stainless steel tubes (CFSSTs). In line with this, the present study investigates the shear response of circular and square CFSSTs using advanced finite element (FE) analysis. A thorough review of the previous studies on the shear response of carbon steel CFTs is provided along with a summary of past experimental programmes as well as the developed and codified design methods. A comprehensive numerical study is then conducted considering a wide range of circular and square, austenitic and lean duplex CFSSTs with different concrete infills and shear span-to-depth ratios. The effect of the tail length on the shear response is investigated and the minimum required tail length for achieving full shear capacity is established. The simulations are also used to highlight the importance of the dilation of the concrete core in the shear response of concrete-filled tubes and its relationship with the utilised boundary conditions. Furthermore, the numerical results are compared in detail with the predictions of design approaches developed previously for carbon steel CFTs and their accuracy and applicability to the stainless steel counterpart are demonstrated and recommendations are made accordingly.

• Biomolecules & Therapeutics
• /
• 제7권2호
• /
• pp.198-203
• /
• 1999

Loxoprofen-Na (sodium 2-〔4-(2-oxocyclopentylmethyl)pheny)propionate dihydrate) is a potent analgesic drug. We developed loxoprofen-Na plasters to extend duration time of analgesic activity and to reduce side effect on gastrointestinal tract. Analgesic effect of Loxoprofen-Na plasters was investigated. Loxoprofen-Na plaster had good analgesic effect in rat paw pressure test, Tail-flick latency test and acetic acid-induced writhing test. Also, it had anti-inflammatory effect on carrageenan-induced rat hind paw edema. In pharmacokinetic study of Loxoprofen-Na, plasters dosage form showed that plasma drug concentration was prolonged up to 14 hours. So, we can conclude that loxoprofen-Na plasters, when applied on skin, will be a new type of drug for controlling the various local pain or inflammation.

• 한국의학물리학회:학술대회논문집
• /
• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
• /
• pp.30-30
• /
• 2006