• Bulletin of the Korean Chemical Society
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• v.12 no.5
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• pp.474-477
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• 1991

The preferential transport phenomena of neutral cation-anion moieties in neutral macrocycle-facilitated emulsion liquid membrane were described in this study. Emulsion membrane systems consisting of (1) aqueous source phase containing 0.001 M M($NO_3$)$_2(M=Mn^{2+},\;Co^{2+},\;Ni^{2+},\;Cu^{2+},\;Zn^{2+},\;Sr^{2+},\;Cd^{2+},\;and\;Pb^{2+})$ (2) a toluene membrane containing 0.01 M ligand $(DBN_3O_2$, DA18C6, DT18C6, TT18C6, HT18C6) and the surfactant span 80 (sorbitan monooleate) (3% v/v) and (3) an aqueous receiving phase containing $Na_2S_2O_3$ or $NaNO_3$ were studied with respect to the disappearence of transition metal ions from the source phase as a function of time. Cation transports for various two component or three component equimolar mixture of transition metal and $Cu^{2+}$ in a emulsion membrane system incorporating macrocyclic ligand (HT18C6) as carrier were determinded. $Cu^{2+}$ was transported higher rates than the other $M^{2+}$ in the mixture solution. Equilibrium constants for cation-source phase co-anion, cation macrocycle and cation-receiving phase reagent interaction are examined as parameters for the prediction of cation transport selectivities.

• Childhood Kidney Diseases
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• v.7 no.1
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• pp.52-59
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• 2003

Purpose : The renin-angiotensin system(RAS) plays an important role in renal growth and development. We have studied the prevalence of renal anomalies and documented the association between karyotype and renal anomalies using IVP and ultrasonography. Furthermore, to investigate the impact of RAS gene polymorphism on renal anomaly in Turner syndrome, we examined the ACE I/D genotype, angiotensinogen(AGT) gene M235T, angiotensin receptor type 1(ATR) gene A1166C. Methods : Cytogenetic analysis was performed in 33 Turner syndrome patients on peripheral blood lymphocytes. Ultrasonography(US) of the kidneys and collecting system and intravenous pyelography(IVP) were perfomed in all patients. Nuclear scintigraphy{Tc 99m dimercaptosuccinic acid(DMSA) scan} was also performed for the definite renal diagnosis if indicated. And, ACE I/D genotype, angiotensinogen(AGT) gene M235T, angiotensin receptor type 1(ATR) gene A1166C were examined by PCR amplification of genomic DNA samples. Results : The prevalence of renal anolmalies in Turner syndrome was 36.4%(12/33). The Karyotype 45, X was observed in 18 of the 33 girls(54.5%), of whom 8(44.4%) had renal anomalies. Mosaic karyotypes were observed in 11(33.3%) and four(12.2%) had a non-mosaic structural aberration of the X chromosome. In this group 4(25.7%) had renal anomalies. More renal anomalies were associated with the 45, X karyotype than those with mosaic/structural abnormalities of X chromosome, but the difference was not statistically significant(P>0.05). And, there was no significant differences in the RAS gene polymorphism and allele frequencies between renal anomaly group and normal group in Turner syndrome. Conclusion : The prevalence of renal anolmalies in Turner syndrome was 36.4%. There is no significant differences in the RAS gene polymorphism and allele frequencies between the renal anomaly group and the normal group in Turner syndrome.

• International Journal of Industrial Entomology and Biomaterials
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• v.5 no.2
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• pp.195-199
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• 2002

In order to find potential anticancer agents, we extracted pheophytin in the silkworm feces from various larval stages by water, chloroform and methanol extraction. The cytotoxicity of the pheophytin extracts of various silkworm feces was measured in the CT-26 cells originated from murine metastatic colon cancer, by dye uptake assay. The cytotoxicity of those pheophytins in 2nd, 3rd and 4th instars was better than remaining larval stages. The in vitro anticoagulant and fibyinolytic activities of ethanol extract from varietal mulberry leaves, mulberry branches and silkworm feces and pheophytin extracts from silkworm feces obtained at various larval stages were evaluated in order to find effective therapeutic drugs for the treatment of myocardial and cerebral thrombosis. The fibrinolytic activity was tested using the activated partial thromboplastin time (APTT) and thrombin time (TT) was measured for blood clotting activity. With regards to the fibrinolytic system, ethanol extracts of silkworm feces were better than varietal mulberry leaves and mulberry branches. The pheophytin extracts from 7th days of 5th instar contained the highest percentage of pheophytin and good fibrinolytic activity.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.337-340
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• 2004

The exactly reproduced prosody of a TTS system is one of the key factors that affect the naturalness of synthesized speech. In general, rules about prosody had been gathered either from linguistic knowledge or by analyzing the prosodic information from natural speech. But these could not be perfect and some of them could be incorrect. So we proposed artificial neural network(ANN)s that can be trained to team the prosody of natural speech and generate it. In learning phase, let ANNs learn the pitch and energy contour of center phoneme by applying a string of phonemes in a sentence to ANNs and comparing the output pattern with target pattern and making adjustment in weighting values to get the least mean square error between them. In test phase, the estimation rates were computed. We saw that ANNs could generate the prosody of a sentence.

• Magazine of the Korean Society of Agricultural Engineers
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• v.15 no.3
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• pp.3089-3095
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• 1973

The power transmission to the traction devices may be very important for the tractor performance and therefore this system has been studied very much in the past. On the other hand, the PTO(Power-take-off) has been considered as an accessary on the tractor with a few work for its power transmission. Because of increased use of PTO operation in various kind of farming operations in recent years, the function of PTO may become such important as the traction facilities. In this study, the power transmission characteristics of PTO drive was analyzed theoretically and some experimental work was done to study on it. The results of the study are as follows: 1) The most stable condition of PTO work was obtained when the intersection angle of the two curves for driving and driven torques was about ${\pi}/2$. 2) To obtain the most stable operation it is better to use both the speed control and the full control together. 3) Six steps differential gear may not be enough to use the PTO power smoothly. It is thought that the three steps differential gear on the shaft of PTO may be necessary additionally for a smooth operation. 4) When the traction facilities and the PTO are used at the same time, the torque of crank shaft becomes Tt + Tp, and the high efficiency and good stability of word will be obtained with the small variation of driving speed. 5) When the tractor was operated with 75% of the rated horse power and 70% of maximum speed, the best thermal efficiency could be obtained. 6) The most dangerous sound for human occured at the rated speed of PTO and tus it may be necessary to control the dangerous noise.

• The Journal of the Korea Contents Association
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• v.12 no.1
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• pp.9-16
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• 2012

Though Android-based smart phones are being released in Korea, Korean TTS engine is not built on them and Google has not announced service or software developer's kit related to Korean TTS officially. Thus, application developers who want to include Korean TTS capability in their application have difficulties. In this paper, we design and implement Android OS-based Korean TTS system and service. For speed, text preprocessing and synthesis libraries are implemented using Android NDK. By using Java's thread mechanism and the AudioTrack class, the response time of TTS is minimized. For the test of implemented service, an application that reads incoming SMS is developed. The test shows that synthesized speech are generated in real-time for random sentences. By using the implemented Korean TTS service, Android application developers can transmit information easily through voice. Korean TTS service proposed and implemented in this paper overcomes shortcomings of the existing restrictive synthesis methods and provides the benefit for application developers and users.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.12
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• pp.1691-1695
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• 2006

The identification method that inflects real time ultrasound (RUT) and the potential application of marker assisted selection (MAS) for improvement of a cow population of Hanwoo (Korean Native cattle) was studied. The averages of RUT longissimus muscle area, RUT fat thickness, and RUT marbling score scanned at the 13th rib were 55.78 $cm^2$, 3.70 mm and 3.83 scores, respectively. We investigated the effects of the two SNPs (Kpn2 I and Msp I) in the leptin gene on carcass traits for Hanwoo cows by using ultrasound measurements. Genotype CC of the Kpn2 I had a significantly higher effect on back fat thickness (4.23 mm) and longissimus muscle area (57.57 $cm^2$) than genotype TT (3.14 mm, 53.93 $cm^2$, respectively, p<0.05). Genotype AA of the Msp I had a significantly higher effect only on marbling score (5.37) than genotype AB (3.57, p<0.05) and BB (3.37, p<0.05). Significant effects of SNPs in the leptin gene were found for the ultrasound measures of body composition in live cattle.

• Korean Journal of Pharmacognosy
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• v.30 no.3
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• pp.231-237
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• 1999

About forty sea weeds were screened for their inhibitory effects against prolyl endopeptidase, tyrosinase and thrombus coagulation. Out of them, methanolic extract of Ecklonia cava, Sargassum patens, Sargassum hemiphyllum, Sargassum thunbergii, Sargassum singgildianum, Hizikia fusiformis, and Ishige okamurae inhibited more than 90% of prolyl endopeptidase activity at 40 ppm. Sargassum siliquastrum and Ecklonia cava exhibited 51% and 76% of inhibitory activity against tyrosinase at 40 ppm, respectively. In APTT assay system, Sargassum singgildianum, Pterocladia capilacea and Hizikia fusiformis delayed coagulation of thrombus about two times (210, 211, and 198% over control at ca 367 ppm, respectively) and in TT assay, Lomentaria catenata, Laurencia okamurae, and Hizikia fusiformis did most effectively (216,197, and 251% at ca 367 ppm, respectively).

• Ocean Systems Engineering
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• v.14 no.2
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• pp.171-210
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• 2024

This paper focuses on the rigorous and holistic fatigue analysis of mooring chains for a deep draft semi-submersible platform in the challenging environment of the central Gulf of Mexico (GoM). Known for severe hurricanes and strong loop/eddy currents, this region significantly impacts offshore structures and their mooring systems, necessitating robust designs capable of withstanding extreme wind, wave and current conditions. Wave scatter and current bin diagrams are utilized to assess the probabilistic distribution of waves and currents, crucial for calculating mooring chain fatigue. The study evaluates the effects of Vortex Induced Motion (VIM), Out-of-Plane-Bending (OPB), and In-Plane-Bending (IPB) on mooring fatigue, alongside extreme single events such as 100-year hurricanes and loop/eddy currents including ramp-up and ramp-down phases, to ensure resilient mooring design. A detailed case study of a deep draft semi-submersible platform with 16 semi-taut moorings in 2,500 meters of water depth in the central GoM provides insights into the relative contributions of wave scatter diagram, VIMs from current bin diagram, the combined stresses of OPB/IPB/TT and extreme single events. By comparing these factors, the study aims to enhance understanding and optimize mooring system design for safety, reliability, and cost-effectiveness in offshore operations within the central GoM. The paper addresses a research gap by proposing a holistic approach that integrates findings from various contributions to advance current practices in mooring design. It presents a comprehensive framework for fatigue analysis and design optimization of mooring systems in the central GoM, emphasizing the critical importance of considering environmental conditions, OPB/IPB moments, and extreme single events to ensure the safety and reliability of mooring systems for offshore platforms.

• Journal of the Korea Society of Computer and Information
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• v.20 no.5
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• pp.53-63
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• 2015

Singing voice synthesis is the generation of a song using a computer given its lyrics and musical notes. Hidden Markov models (HMM) have been proved to be the models of choice for text to speech synthesis. HMMs have also been used for singing voice synthesis research, however, a huge database is needed for the training of HMMs for singing voice synthesis. And commercially available singing voice synthesis systems which use the piano roll music notation, needs to adopt the easy to read standard music notation which make it suitable for singing learning applications. To overcome this problem, we use a speech database for training context dependent HMMs, to be used for singing voice synthesis. Pitch and duration control methods have been devised to modify the parameters of the HMMs trained on speech, to be used as the synthesis units for the singing voice. This work describes a singing voice synthesis system which uses a MusicXML based music score editor as the front-end interface for entry of the notes and lyrics to be synthesized and a hidden Markov model based text to speech synthesis system as the back-end synthesizer. A perceptual test shows the feasibility of our proposed system.