• Title/Summary/Keyword: TRZ

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Infranuchal Infrafloccular Approach to the More Vulnerable Segments of the Facial Nerve in Microvascular Decompressions for the Hemifacial Spasm

  • Park, Heung-Sik;Chang, Dong-Kyu;Han, Young-Min
    • Journal of Korean Neurosurgical Society
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    • v.46 no.4
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    • pp.340-345
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    • 2009
  • Objective : We investigated the locations of compressing vessels in hemifacial spasm. To approach compression sites, we described and evaluated the efficacy of the infranuchal infrafloccular (INIF) approach. Methods : A retrospective review of 31 consecutive patients who underwent microvascular decompression (MVD) through INIF with a minimum follow-up of 1 year was performed. Along the intracranial facial nerve, we classified the compression sites into the transitional zone (TRZ), the central nervous system (CNS) segment and the peripheral nervous system (PNS) segment. The INIF approach was used to inspect the CNS segment and the TRZ. Subdural patch graft technique was used in order to achieve watertight dural closure. The cranioplasty was performed using polymethylmethacrylate. The outcome and procedure-related morbidities were evaluated. Results : Twenty-nine patients (93%) showed complete disappearance of spasm. In two patients, the spasm was resolved gradually in 2 and 4 weeks, respectively. Late recurrence was noted in one patient (3%). The TRZ has been identified as the only compression site in 19 cases (61.3%), both the TRZ and CNS segment in 11 (35.5%) and the CNS segment only in 1 (3.2%). There was no patient having a compressing vessel in the PNS segment. Infection as a result of cerebrospinal fluid leak occurred in one patient (3%). Delayed transient facial weakness occurred in one patient. Conclusion : The TRZ and the CNS segment were more vulnerable area to the compression of vessels. We suggest that surgical avenue with the INIF approach provides early identification of this area.

광독성, 광알러지성 물질의 안정성과 생체이용율증가 및 기전 연구

  • 김봉희;문창규
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.101-101
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    • 1993
  • 사용한 CPZ, PPZ, TFZ 및 TRZ의 약물이 UVA조사에 의해 용혈독성이 크게 나타났으며 CPZ, PPZ, TRZ에 의한 광용혈정도는 ascorbic acid에 의해 유의성 있게 감소되었다. 또한 적혈구를 가하기 전 각 약물을 미리 조사시켜 생성된 물질에 의한 광용혈현상의 광독성생성물질은 chlorpromazine과 thioridazine에서 보여졌으며, cholrpromazine의 광독성생성물질에 의한 적혈구 용혈현상만 ascorbic acid에 의해 감소되었다. UVA조사전 후의 각 약물에 대한 TA98, TA100에서의 발암성은 인정되지 않았다.

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DFT and Time-dependant DFT Investigation of eLectronic Structure, Phosphorescence and Electroluminescence Properties of Iridium (III) Quinoxaline Complexes (Iridium (III) quinoxaline 착물의 전자 구조, 인광 및 전기 발광 특성에 대한 DFT 및 시간-의존 DFT 연구)

  • Zhou, Xiao-Qing;Li, Ying;Sun, Yan-Bo;Zhang, Hong-Xing
    • Journal of the Korean Chemical Society
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    • v.55 no.3
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    • pp.354-363
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    • 2011
  • Quantum-chemistry study was explored to investigate the electronic structures, absorption and phosphorescence mechanism, as well as electroluminescence (EL) properties of three red-emitting Ir(III) complexes, $(fpmqx)_2Ir$(L) {fpmqx=2-(4-fluorophenyl)-3-methyl-quinoxaline; L=triazolylpyridine (trz) (1); L=picolinate (pic) (2) and L=acetylacetonate (acac) (3)}. The calculated results show that the HOMO distribution for 1 is mainly localized on trz moiety due to its stronger ${\pi}$-electron acceptor ability, and HOMO for 2 and 3 is the combination of Ir d- and phenyl ring ${\pi}$-orbital. The higher phosphorescence yields and differences among 1-3 are investigated in this paper. In addition, the reasons of higher EL efficiency of 2 than 1 and 3 have been rationalized.

Plan for Increasing the Analysis and Understanding Skills of Literary Works based on Systems Thinking Technique (시스템 사고 기법 기반의 문학 작품 분석 및 이해력 신장 방안)

  • Kim, Hun-Hee
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.662-669
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    • 2015
  • The purpose of this study is to explore plan for increasing the analysis and understanding skills of literary works by using systemic thinking technique. This study used a literatures analysis method. The concrete study contents are as follows; First, it is centered on presenting values of literary education through analysing fairy tales conditions in Korean textbooks in relation to national curriculum for elementary and middle school. Second, it is to explore the features of systemic thinking technique. Third, it is to draw the instruction design model and application. Main expected effects of this study are breakaway from habitual routine, developing comprehensive and logical thinking ability, expanding fancy and imagination, cultivating innovative problem solving skill, inducing interest in literature, and increasing linguistic skills. That is, it is to be effective instruction strategy to enhance creativity and to cultivate character in classroom.

Arthrobacter sp. Strain KU001 Isolated from a Thai Soil Degrades Atrazine in the Presence of Inorganic Nitrogen Sources

  • Sajjaphan, Kannika;Heepngoen, Pimpak;Sadowsky, Michael J.;Boonkerd, Nantakorn
    • Journal of Microbiology and Biotechnology
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    • v.20 no.3
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    • pp.602-608
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    • 2010
  • An atrazine-degrading bacterium, strain KU001, was obtained from a sugarcane field at the Cane and Sugar Research and Development Center at the Kasetsart University, Kamphaeng Saen Campus, Thailand. Strain KU001 had a rod-to-coccus morphological cycle during growth. Biolog carbon source analysis indicated that the isolated bacterium was Arthrobacter histidinolovorans. Sequence analysis of the PCR product indicated that the 16S rRNA gene in strain KU001 was 99% identical to the same region in Arthrobacter sp. The atrazine degradation pathway in strain KU001 consisted of the catabolic genes trzN, atzB, and atzC. Strain KU001 was able to use atrazine as a sole nitrogen source for growth, and surprisingly, atrazine degradation was not inhibited in cells grown on ammonium, nitrate, or urea, as compared with cells cultivated on growth-limiting nitrogen sources. During the atrazine degradation process, the supplementation of nitrate completely inhibited atrazine degradation activity in strain KU001, whereas ammonium and urea had no effect on atrazine degradation activity. The addition of strain KU001 to sterile or nonsterile soils resulted in the disappearance of atrazine at a rate that was 4- to 5-fold more than that achieved by the indigenous microbial community. The addition of citrate to soils resulted in enhanced atrazine degradation, where 80% of atrazine disappeared within one day following nutrient supplementation.