• 제목/요약/키워드: TPO

검색결과 142건 처리시간 0.026초

The application of rapid SIMS analysis for the identification of surface contamination in TFT-LCD manufacturing

  • Liou, Been-Chih;Chou, Yi-Hung;Chen, Chien-Chih;Eccles, John A.
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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    • pp.665-668
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    • 2006
  • Sodium is a serious contamination in LTPS TFT process. It causes the abnormal characteristics of TFT in operation. Contaminated areas can be seen in SEM images, but EDX measurements do not have adequate sensitivity to confirm the presence of superficial sodium residues. We employed SIMS as a fast analysis method to map the non-uniform distribution of sodium on the surface. SIMS can also indicate the thickness of the contamination.

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우레팔트 접착제를 사용한 개량형 우레시트 일체식 공기단축형 기계화 시공 비노출 방수공법 (The Automatic equipments Non-Exposure waterproofing method of reduced construction hours integrated with the improved URE-Sheet and UREPALT adhesives)

  • 민성우;오창원;양재봉
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2009년도 춘계 학술논문 발표대회 산업계
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    • pp.135-141
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    • 2009
  • This technology is able to construct with hardening UREPALT adhesives and TPO URE-Sheet simultaneously using automatic equipments. the benefit of this construction method is that The layer of waterproofing is uniform and defect of construction would be reduced because of no construction joints between UREPALT adhesives and TPO URE-Sheet. Furthermore, this new method could accomplish shortening of construction period, quality control and saving of labor costs. Also the non-exposure waterproofing method would be protected from fire and safe for workers without using a torch.

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EFFECT OF DOXYCYCLINE-REGULATED ERP57 EXPRESSION ON THROMBOPOIETIN PRODUCTIVITY IN RECOMBINANT CHO CELLS

  • 황선옥;정주영;이균민
    • 한국생물공학회:학술대회논문집
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    • 한국생물공학회 2001년도 추계학술발표대회
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    • pp.457-458
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    • 2001
  • To determine the effect of ERp57 expression on thrombopoiein (TPO) productivity in recombinant Chinese hamster ovary (rCHO) cells, TPO producing rCHO cell line with doxycycline-regulated ERp57 expression \Vas developed. The Erp57 expression level could be regulated by addition of different concentrations of doxycycline to culture medium. The doxycycline concentration of I ${\mu}g/mL$ was high enough to suppress the ERp57 expression. Up to 5 ${\mu}g/mL$ doxycycline concentration used in culture medium, no observable cytotoxic effect of doxycycline was detected during culture. Overexpression of ERp57 、 vas found to increase the specific TPO productivity ($q_{Tpo}$) without growth inhibition, probably due to the chaperone-like activity of ERp57 in CHO cells.

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녹용이 Acute-Phase Reactants에 미치는 영향

  • 한용남
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1993년도 제2회 신약개발 연구발표회 초록집
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    • pp.124-124
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    • 1993
  • 녹용은 강심작용, 여성홀몬작용, 강장작용, 창상치유작용 등의 약리작용이 있는 것으로 보고되어 있는데 녹용의 상용량에서는 강장작용, 창상치유작용이 있는 것으로 알려져 있다. 녹용의 창상치유작용은 생체내 질소 평형이 음의 방향으로 되었을 때 이를 빠른 시간내에 정상적으로 회복시키는 약리효과에 기인하는 것으로 볼 수 있겠다. 본 연구에서도 흰쥐에 turpentineee oil (TPO)를 주사하여 acute-phase response를 일으켜 질소평형을 깨뜨린 실험 모델에서 녹용의 효과를 측정하였다. Acute-phase reactants중에서 $\alpha$$_2$-macroglobulin, $\alpha$$_1$-cysteine pretense inhibitor (T-kininogen), ceruloplasmin을 측정 하였는데 이 중에서 creuloplasmin의 측정이 재현성이 높았다. TPO로 급성염증을 유발시키면 2일 후에 ceruloplasmin의 혈청내 농도가 약 100% 증가하며 4일까지 지속하다가 5일째부터 감소하는데 이때 미리 녹용추출물을 투여한 군은 TPO주사 후 4일째에 50% 감소하였다. TPO로 염증을 유발하기 전에 녹용을 투여했을 때가 염증유발 후에 투여했을 때보다 녹용의 효과가 현저히 나타났다. 이러한 결과는 급성염증에 의해 깨어진 단백질 평형을 신속히 정상화시키는 효과가 있음을 나타내는 것으로 이러한 녹용의 효과를 지표로 하여 녹용의 유효성분 분리를 수행하고자 한다.

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옥상 및 인공지반 방근공사에 적용되는 TPO시트의 재생 소재 적용에 따른 인장성능 변화 연구 (Study on tensile performance change by recycled materials of TPO sheet applied to rooftop and artificial ground Rootproofings)

  • 김선도;김진성
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2018년도 춘계 학술논문 발표대회
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    • pp.103-104
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    • 2018
  • Recently, in addition to greening of roof and artificial soil, Rootproofing to prevent damage to the waterproof layer and structures by roots is recognized as an important task. Therefore, various related products and construction methods have been developed and applied in the field. However, in the case of synthetic polymer-based sheets most commonly used in domestic construction sites, Most are produced using 100% new materials that are not suitable for green trends such as resource conservation and environmental protection. Therefore, in this study, we developed TPO sheet using recycled material, which is a technology that can secure eco-friendliness by utilizing recycled resources. As a result of the evaluation of tensile performance of the TPO sheet according to the recycled material content, The tensile strength of the specimens with the recycled content of 50 ~ 70% was the highest, The elongation rate of the specimen with the recycled content of 30 ~ 40% was the best.

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The Receptor-Ligand Interaction Revealed by a Homology Modelling of the Receptor Binding Domain of Human Thrombopoietin

  • Song, Jin-Soo;Park, Heung-Rok;Hong, Hyo-Jeong;Yu, Myeong-Hee;Ryu, Seong-Eon
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 1997년도 학술발표회
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    • pp.43-43
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    • 1997
  • Platelet production in blood is regulated by a lineage specific humoral factor called thrombopoietin (TPO). The amino terminal domain of TPO (TPO-N) has a sequence homology to erythropoietin (EPO) and is responsible for the signal transduction mediated by the TPO receptor, c-mpl.(omitted)

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Enhanced Thermal Stability of a Novel Human Thrombopoietin Mutein under the Various Temperature Conditions

  • Kim, Tae-Soo;Ahn, Hye-Kyung;Lim, Seung-Wook;Hong, Yeon-Joo;Chung, Joo-Young;Koh, Yeo-Wook
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.237.2-237.2
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    • 2003
  • DWP40458 is a novel human thrombopoietin mutein with two additional N-linked glycosylation site. The thermal stability of DWP40458 in both solution and lyophilized form was studied in the temperature range of 4-50$^{\circ}C$, compared with recombinant human TPO (rhTPO). When the aggregation or degradation pattern of DWP40458 and rhTPO solution was characterized by using SDS-PAGE, gel permeation chromatography (GPC) and reverse phase HPLC, it was found that thermostability of DWP40458 was significantly different to rhTPO in the temperature at 25, 40, 40, 50$^{\circ}C$. (omitted)

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Conditions for Selection of Targeted Colonies in the Primary Cells

  • Chang, Mi-Ra;Oh, Keon-Bong;Lee, Kyung-Kwang;Han, Yong-Mahn
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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    • pp.55-55
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    • 2003
  • The random insertion of useful gene in genome has been a common method to produce transgenic animals. This method is inefficient for induction of high levels gene expression in transgenic animals. To improve this limit, we tried to develop the system which target the gene at the specific genomic region. Thus, in our experiment, the vector system to target the human thrombopoietin (TPO) gene was developed. Targeting vector including TPO, neo and DT genes was transfrcted into bovine embryonic fibroblasts (bEF) or bovine ear skin fibroblasts (bESF). First of all, we determined concentration of the geneticin (G418) for selection of transfected cell lines. Our results showed that 1200 and 900 $\mu\textrm{g}$/ml of G418 were the most proper for selection of transfscted bEF and bESF cells. In this study, lipofectamine was used as a transfection reagent. Thus, the proper ratio of DNA:lipofectamine for transfection was also required to elevate targeting efficiency in primary mammalian cells. Our result indicates that the most proper ratios of DNA:lipofectamine were 4:2 and 1:2 in bEF and bESF cells. According to the optimized these conditions, single colonies were picked following transfection and were analyzed by PCR. More than 90% of the single colonies have TPO gene. However, there were no colonies with targeted TPO at the specific genomic region. Therefore, further experiments to select the specifically targeted colonies and to find more efficient methods such as reducing selection time and shortening a size of TPO gene are required.

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동일배열 폴리프로필렌/엘라스토머/나노충전제 복합체의 전력케이블 절연체로서의 사용 가능성에 대한 문헌적 고찰 (A Review on IPP/Elastomer/Nanofiller Composites for the Possibility of Use as Power Cable Insulations)

  • 변선호
    • 한국응용과학기술학회지
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    • 제29권2호
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    • pp.184-192
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    • 2012
  • 본 논문은 절연유 불포함 재활용 가능 전력케이블 절연체에 동일배열 폴리프로필렌(IPP) 기반 열가소성 폴리올레핀 엘라스토머(TPO) 나노복합체 사용 가능성을 문헌적으로 고찰한 리뷰논문이다. 2010년 IPP 기반 나노복합 유전체는 파워 커패시터 연구에서 유전손실을 제외한 고전압 특성이 크게 향상되었다. IPP 기반 TPO 나노복합체 사용 자동차 외장부품 연구에서는 나노충전제 최대 3 wt% 함유로 전력케이블 절연체의 필수특성인 저온 충격성을 비롯한 기계적 특성향상이 보고 되었다. 특히 유전손실의 원천인 상용화제 사용의 최소화 기술이 보고되어, 3 wt% 이하 나노충전제 함유 IPP 기반 TPO의 전기적 특성조사가 필요하다.