• Journal of Oral Medicine and Pain
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• v.24 no.4
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• pp.467-477
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• 1999

Personality characteristics of orofacial pain patients was analyzed psychologically by means of the SCL-90-R. 36 TMD patients, 20 burning mouth syndrome(BMS) patients, 31 trigeminal neuralgia(TN) patients, 20 control I and 28 control II were subjected at Orofacial pain clinic, Department of Oral Medicine and Health Promotion Center, Pusan National University Hospital during the period from 1998 to 1999. The obtained results were as follows: 1. Mean values of T-scores on 9 basic scales in all the groups were within normal range. 2. The T-scores of SOM, O-C, ANX and HOS in TMD patient group were significantly higher than those in control I group, but there was no significant difference in all scales between TMD patient group and control II group. 3. The T-scores of SOM in BMS patient group was significantly higher than those in control I group, but there was no significant difference in all scales between BMS patient group and control II group. 4. The T-scores of SOM in TN patient group was significantly higher than those in control II group. 5. As compared with present and absent of the history of systemic diseases, there was no significant difference of the scales in TMD, BMS and TN patient groups but the T-scores of the patient groups with the history of systemic diseases tended to higher than those of the patient group without the history of systemic diseases. 6. As compared with acute and chronic groups, the T-scores of O-C, I-S, PAR, PSY in chronic BMS patient group were significantly higher than those in acute BMS patient.

• Journal of environmental and Sanitary engineering
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• v.12 no.3
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• pp.1-7
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• 1997

이 연구에서는 SBR 공법을 이용하여 질소, 인 동시제거기장에 대해 관찰하고 BOD-SS loading변화에 따른 오염물질 제거효율에 대해 검토하였다. BOD, TN 및 TP 제거율은 $20^{\circ}C$에서 95%, 74% and 81%로 나타났으며, Phosphorus luxury uptake는 호기성이 시작된후 1,2시간후에 각각 67% 및 84%를 흡수 하는 것으로 관찰 되었으며, 호기성 말기의 농도는 $0.9mg/{\ell}$ 이하를 유지하였다. 80% 및 85% 이상의 안정된 질소 제거효율을 유지하기 위해서는 BOD-SS loading 값을 0.15 및 0.08 kg-BOD/kg-SS.day 이하로 유지하여야 하는 것으로 나타났다. 또한 1회 방류수량의 변화에 따른 관찰에서, 반응조 유효용량의 30%, 40% 및 50%를 유출할 경우 TN은 각각 78%, 72% 및 58%를 TP는 각각 81%, 77% 및 66%의 제거효율을 보였다.

• Bulletin of the Korean Chemical Society
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• v.4 no.2
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• pp.76-79
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• 1983

The elution behaviors of a series of metal complexes, such as $Co(gly)_{3}$, $[Ni(en)_{3}]^{2+}$, $[Ni(phen)_3]^{2+}$, $[Fe(phen)_3]^{2+}$, $[Co(phen)_3]^3+$, $[Co(tn)_3]^3+$, $[Co(en)_3]^3+$ and $[Co(NH_3)_6]^3+$ (where gly; glycine, phen; phenanthroline, tn; trimethylenediamine, en; ethylenediamine), were studied in aqueous solution by measuring the retention volumes (v values) on SP-Sephadex C-25, cation exchange resin. It was found that the elution behaviors of metal complexes were apparently affected by salt concentrations, kinds of cations in eluent and kinds of anions in eluent, and according to the degrees of their effects coulombic forces, ion exchange capacities, the 'solvent effect' of resin backbone, hydrophobicity and hydrophilicity were applied to explain the elution mechanism.

• The Journal of Korean Society for Radiation Therapy
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• v.24 no.2
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• pp.197-203
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• 2012

Purpose: In this study, we considerate our radiation therapy process for the breast cancer patient implanted a pacemaker applying the machine movement surgery, shielding, beam selection. Materials and Methods: We perform radiation therapy to a 54 years old, breast cancer patient implanted a pacemaker. The patient underwent a surgery to move the position of a pacemaker to right side breast after consultation with cardiology department. Prescribed dose was 5,040 cGy and daily dose 180 cGy for 28 fractions. The 10 MV photon energy, field size 0/$9.5{\times}20$ cm, half beam and opposing portal irradiation are used. To find out appropriate thickness of shielding board, we carried out an experiment using a solid water phantom ($30{\times}30{\times}7$ cm), a Farmer-type chamber (TN30013, PTW, Germany) and a shielding board (Pb $28{\times}27{\times}0.1$ cm). We calculated expected absorbed dose to te pacemaker with absorb ratio and shielding ratio. In the PTP system (Eclipse, Varian, USA), we figured out how much radiation would be absorbed to the machine with and without shielding. First day of the radiation therapy, we measured head scatter to the pacemaker with MOSFET Dose Verification System (TN-RD-70-W, Medical Canada Ltd., Canada). Results: In the phantom measurement, we found out appropriate thickness was 2 mm of shielding board. In the RTP, when using 2 mm shielding the pacemaker will be absorbed 11.5~38.2 cGy and DVH is 77.3 cGy. In the first day of the therapy, 4.3 cGy was measured so 120.4 cGy was calculated during total therapy. The patient was free from any side effects, and the machine also normally functioned. Conclusion: As the report of association which have public confidence became superannuated, there is lack of data about new machine. We believe that radiation therapy to thiese kind of patients could be done successfully with co-operation, patient-suitable planning, accurate QA, frequent in-vivo dosimetry and monitoring.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.1
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• pp.17-21
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• 2018

Our previous studies have confirmed that morroniside has neuroprotective effects. However, the effects of morroniside on cardiac myocardium remain unknown. Rats were anaesthetized with 10% chloral hydrate (0.35~0.4 mL/kg) and an acute myocardial infarction (AMI) was induced by ligating the anterior descending coronary artery (LAD). Following AMI, morroniside was administered intragastrically for 3 consecutive days at doses of 45, 90 and 180 mg/kg, respectively. Lactate dehydrogenase (LDH) and cardiac troponin T (cTnT) activities in AMI rats in the serum were detected with commercial kits. The expression of IL-6, $IL-1{\beta}$ and $TNF-{\alpha}$ in myocardium was detected by Western blotting analysis. We observed a significant decline in the Q(q) wave amplitude in morroniside-treated rats after 72 h. Additionally, treatment of morroniside decreased the levels of LDH and cTnT in AMI rats. We also observed that morroniside reduced the expression of IL-6, $IL-1{\beta}$ and $TNF-{\alpha}$ in myocardium. Taken together, our findings demonstrate that morroniside had effective anti-inflammatory properties in AMI rats.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.11a
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• pp.297-298
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• 2005

We have fabricated twisted nematic (TN) liquid crystal cells doped by carbon nanotubes (CNTs) with different CNT wt. %. With a minute amount doping, multi-walled CNTs did not perturb the liquid crystal orientations at the off- and on-state. The hysteresis studies of voltage-dependent capacitance (V-C) under the influence of electric field generated by ac and dc voltage show that the residual do, which is tightly related to image sticking problem in liquid crystal displays, is greatly reduced due to ion trapping by CNTs. Also, the V-C hysteresis shows dependency of capacitance on concentration of multi-walled CNTs.

• Transactions of the Society of Information Storage Systems
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• v.9 no.1
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• pp.28-31
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• 2013

We proposed a method to fabricate label-free protein sensor with sub-wavelength nanograting structures to be used for diagnosing acute myocardial infarction. A nickel stamp for the injection molding of nanograting integrated protein sensor was fabricated by electroforming process with high fidelity. By using metallic stamp, we replicated label-free protein sensor via injection molding, which is an outstanding method for low-cost and mass production of polymer products. Finally, we performed a feasibility test, examining cardiac troponin T (cTnT) and anti-cTnT interactions. From the results, we demonstrated that the fabricated protein sensor can provide information for the early and accurate detection of cardiac diseases such as acute myocardial infarction.

• Korean Circulation Journal
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• v.48 no.11
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• pp.1014-1024
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• 2018

Background and Objectives: Intense exercise (IE) induced myocardial fibrosis (MF) showed contradictory findings in human studies, making the relationship between IE and the development of MF unclear. This study aims to demonstrate exercise induced MF is associated with cardiac damage, and inflammation is essential to the development of exercise induced MF. Methods: Sprague-Dawley rats were submitted to daily 60-minutes treadmill exercise sessions at vigorous or moderate intensity, with 8-, 12-, and 16-week durations; time-matched sedentary rats served as controls. Enzyme-linked immunosorbent assay (ELISA) was used to measure serum cardiac troponin I (cTnI) concentration. After completion of the exercise protocol rats were euthanized. Biventricular morphology, ultrastructure, and collagen deposition were then examined. Protein expression of interleukin $(IL)-1{\beta}$ and monocyte chemotactic protein (MCP)-1 was evaluated in both ventricles. Results: After IE, right but not left ventricle (LV) MF occurred. Serum cTnI levels increased and right ventricular damage was observed at the ultrastructure level in rats that were subjected to long-term IE. Leukocyte infiltration into the right ventricle (RV) rather than LV was observed after long-term IE. Long-term IE also increased protein expression of proinflammation factors including $IL-1{\beta}$ and MCP-1 in the RV. Conclusions: Right ventricular damage induced by long-term IE is pathological and the following inflammatory response is essential to the development of exercise induced MF.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.6
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• pp.511-518
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• 2022

Sepsis-associated myocardial injury, an invertible myocardial depression, is a common complication of sepsis. Neogambogic acid is an active compound in garcinia and exerts anthelmintic, anti-inflammatory, and detoxification properties. The role of neogambogic acid in sepsis-associated myocardial injury was assessed. Firstly, mice were pretreated with neogambogic acid and then subjected to lipopolysaccharide treatment to induce sepsis. Results showed that lipopolysaccharide treatment induced up-regulation of biomarkers involved in cardiac injury, including lactate dehydrogenase (LDH), creatine kinase-MB (CK-MB), and troponin I (cTnI). However, pretreatment with neogambogic acid reduced levels of LDH, CK-MB, and cTnI, and ameliorated histopathological changes in the heart tissues of septic mice. Secondly, neogambogic acid also improved cardiac function in septic mice through reduction in left ventricular end-diastolic pressure, and enhancement of ejection fraction, fractional shortening, and left ventricular systolic mean pressure. Moreover, neogambogic acid suppressed cardiac apoptosis and inflammation in septic mice and reduced cardiac fibrosis. Lastly, protein expression of p-p38, p-JNK, and p-NF-κB in septic mice was decreased by neogambogic acid. In conclusion, neogambogic acid exerted anti-apoptotic, anti-fibrotic, and anti-inflammatory effects in septic mice through the inactivation of MAPK/NF-κB pathway.

• Korean Journal of Ecology and Environment
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• v.44 no.1
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• pp.9-21
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• 2011

This study is conducted to know the change in water environment of Lake Hwajinpo from 2000 to 2008 with physico-chemical parameters; salinity, dissolved oxygen, total phosphorus and total nitrogen and others. And zooplanktons and phytoplanktons were studied from 2007 to 2008. From the water quality data of Lake Hwajinpo from 2000 to 200S; water temperature, salinity, transparency, chemical oxygen demand and dissolved oxygen ranges are $2.8{\sim}29.4^{\circ}C$, 0.23~33.2‰, $0.2{\sim}1.8\;m$, $0.2{\sim}20.2\;mg\;L^{-1}$ and $0.1{\sim}17.4\;mg\;L^{-1}$ and the average values are $18.0^{\circ}C$, 15.7‰, 0.7 m, $5.7\;mg\;L^{-1}$ and $8.0\;mg\;L^{-1}$, respectively. Total phosphorus (TP) and total nitrogen (TN) ranges are $0.024{\sim}0.869\;mg\;L^{-1}$ (average 0.091) and $0.240{\sim}5.310\;mg\;L^{-1}$ (average 1.235). Average TN/TP ratio is 16.4. The annual variations in COD, TP, TN and Chl.${\alpha}$ are compared. COD in 2000 is $4.83\;mg\;L^{-1}$ and 2008 is $1.80\;mg\;L^{-1}$ which is reduced by $0.34\;mg\;L^{-1}$ every year. TP in 2000 is $0.07\;mg\;L^{-1}$ and 2008 is $0.05\;mg\;L^{-1}$ reduced gradually. Yearly reduction in TN is $0.09\;mg\;L^{-1}$, in 2000 and 2008 the values are $1.54\;mg\;L^{-1}$ and $0.77\;mg\;L^{-1}$ respectivly. Chl.${\alpha}$ in 2000 is $46.30\;{\mu}g\;L^{-1}$ and $5.78\;{\mu}g\;L^{-1}$ in 2008; yearly reduction is $4.50\;{\mu}g\;L^{-1}$. The tropic state index (TSI) in south and north parts of Lake Hwajinpo in 2000 are 67 and 63 which are reduced to 63 and 59 in 2008 respectively. North and south part of Lake Hwajinpo have 67 species of phytoplankton under 47 families in 2007 and 2008. Dominant species in south part in 2007 are; Asterococcus superbus in May, Lyngbya sp. in September and Trachelomonas spp. in November and in 2008 Anabaena spiroides in August are abundant and varies with time. Zooplankton species in Lake Hwajinpo are 25 of 25 families. Dominant species in south part in May and August 2007 and May and November in 2008 Copepoda larvae and in September 2007 Protozoa spp. of Protozoan and Brachionus plicatilis and Brachionus urceolaris of Cladocera in August 2008. Dominant species in north part Asplanchna sp. of Cladecera in August and November 2007 and rest of the time are larvae of Copepoda. In this way, the water quality of Lake Hwajinpo is changing with slow rate in the long period specially nutrients concentration (TP, TN etc) is decreasing.