• 제목/요약/키워드: TN cell

검색결과 207건 처리시간 0.026초

Inhibition by Imatinib of Expression of O-glycan-related Glycosyltransferases and Tumor-associated Carbohydrate Antigens in the K562 Human Leukemia Cell Line

  • Sun, Qi-Chang;Liu, Mi-Bo;Shen, Hong-Jie;Jiang, Zhi;Xu, Lan;Gao, Li-Ping;Ni, Jian-Long;Wu, Shi-Liang
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2447-2451
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    • 2013
  • Objective: To study changes of tumor associated carbohydrate antigen (TACAs) expression and mRNA levels for tumor associated glycosyltransferases, and assess subcellular localizations of N-acetyl galactosyltransferases (GalNAc-Ts) in the K562 leukemia cell line after imatinib treatment. Methods: RT-PCR was performed to analyze the expression of glycosyltransferases which synthesize O-glycan in tumor-associated carbohydrate antigens (TCTAs). The expression of Tn antigen, T antigen and sialyl T antigen on K562 cell membranes was measured by flow cytometry after treatment with different concentrations of imatinib. Co-localization of GalNAc-Ts and ER (endoplasmic reticulum) was determined by confocal laser scanning microcopy. Results: Transcript expression levels of several glycosyltransferases related to TCTAs were decreased after imatinib ($0-0.3{\mu}M$) treatment. Expression of Tn antigen and T antigen was increased while that of sialyl T antigen was decreased. Co-localization of GalNAc-Ts and ER was reduced by $0.2{\mu}M$ of imatinib. Conclusion: Imatinib inhibited the expression of O-glycan related TACAs and several related glycosyltransferases, while decreasing the co-localization of GalNAc-Ts and ER and normalizing O-glycosylation in the K562 human leukemia cell.

유전율 이방성이 음인 액정을 이용한 Fringe-field Switching Twisted Hematic 모드의 전기광학 특성 연구 (Study on Electro-optic Characteristics of Fringe-field Switching Twisted Nematic Mode using a Liquid Crystal with Negative Dielectric Anisotropy)

  • 송일섭;신성식;이종문;이승희
    • 한국전기전자재료학회논문지
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    • 제17권5호
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    • pp.530-535
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    • 2004
  • We have studied 90$^{\circ}$ twisted nematic mode switching by fringe electric field(F-TN mode) using a liquid crystal (LC) with negative dielectric anisotropy. In the device, two polarizers are parallel each other, electrodes exist only on bottom substrate, and one of rubbing direction is coincident with polarizer axis. Therefore, the cell shows a black state before a voltage is applied. With a bias voltage generating fringe-electric field, the LC twists perpendicular to fringe electric field such that the LCs are almost homogeneously aligned except near the bottom surface since the negative type of the LC is used. Consequently, the new device exhibits much wider viewing angle than that of the conventional TN mode due to in-plane switching and relatively high transmittance since the LC director above whole electrode area aligns parallel to the polarizer axis.

탄소 나노 튜브가 분산된 액정을 이용한 TN 모드의 전기 광학 특성 연구 (Electro-optic Characteristic of Twisted Nematic Mode using a Liquid Crystal Dispersed Carbon Nanotubes)

  • 백인수;전상연;이승희
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2005년도 춘계학술대회 논문집 디스플레이 광소자 분야
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    • pp.114-117
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    • 2005
  • We have fabricated twisted nematic (TN) cell doped by carbon nanotubes (CNTs). The CNTs with a minute amount of doping do not perturb the liquid crystal orientation in the off- and on-state. The hysteresis studies of voltage-dependent transmittance and capacitance under ac and dc electric field show that the amount of residual dc, which is related to image sticking problem in liquid crystal displays, is greatly reduced due to ion trapping by CNTs.

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LEO NTN 을 위한 UE 와 셀 중심간 거리 및 고도각을 사용한 핸드오버 예측 시스템 (Intra Low Earth Orbit Non-Terrestrial-Network User Equipment Handover prediction system based on cell center distance and elevation angle)

  • 김은수;조인휘
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2023년도 춘계학술발표대회
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    • pp.64-66
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    • 2023
  • Low Earth Orbit(LEO) Non-Terrestrial-Network(NTN) 은 위성을 사용하여 통신 서비스를 제공하지 못하는 도시 이외의 산간, 바다, 항공기 또는 외진 지역에 통신 서비스를 제공하는 모델이다. Terrestrial Network(TN) 핸드오버에서 사용되는 Measurement-Based Triggering(MHT)의 경우 User Equipment(UE)에서 측정된 값을 기반으로 Measurement Report를 전달한다. 그러나 NTN 환경에서의 HO triggering은 TN 과는 달리 장거리 통신을 요구하고 위성이 빠른 속도로 이동함에 따라 MHT에 사용되는 지표들을 대체할 방법이 필요하다. 이 논문에서는 측정 유효성을 대체할 수 있는 지표로 UE와 셀 중심 간의 거리 및 고도 각을 활용하여 HO triggering을 예측하는 시스템을 제안한다. 제안한 예측 시스템은 핸드오버 triggering 예측에 대해 우수한 성능을 보였으며 좋은 측정 결과를 얻을 수 있었다.

Study of Optimized Condition for Bend State in Polymer Stabilized Pi-cell with Compensation Films

  • Jeong, Seung-Yeon;Shin, Hyun-Ho;Bos, Phil;Shin, Sung-Tae
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2003년도 International Meeting on Information Display
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    • pp.589-594
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    • 2003
  • The pi-cell [1] is known as one of the candidates for a fast response time and a good viewing angle characteristics due to a self-compensated configuration and can be a replaceable mode instead of the current TN mode and the IPS mode for moving picture in future. This paper shows the optimized condition to maintain bend state instead of splay state, which is mortal demerit for good optical properties in a pi-cell, by using the polymer stabilized method [2]. The good electro-optical characteristics are also obtained by optimizing the various factors, which are monomer concentration in a LC, UV intensity, curing time, curing voltage, and curing temperature, and by using retardation film. We use a scanning electron microscope to study the structures of the polymer stabilized polymer network in a pi-cell as a key to figure out why bend state is occurred.

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스핀 코팅 공정에 따른 액정디스플레이용 폴리이미드 배향막 특성 분석 (Effect of Spin Coating Speed on Characteristics of Polyimide Alignment Layer for Liquid Crystal Display)

  • 김진아;최세훈;박홍규
    • 한국전기전자재료학회논문지
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    • 제35권1호
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    • pp.58-65
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    • 2022
  • The field of liquid crystal display (LCD) is constantly in the spotlight and the process of depositing an alignment layer in the LCD manufacturing process is very important to obtain excellent performance such as low-power driving and high-speed response to improve LCD performance. Therefore, research on liquid crystal (LC) alignment is being actively conducted. When manufacturing LCD, it is necessary to consider the effect of the alignment layer thickness as one of the factors affecting various LCD performances. In addition, previous studies confirmed the LC alignment characteristics correlate with the rotation speed in the spin coating process. Therefore, the electro-optical properties of the LCD were investigated by manufacturing a polyimide alignment layer by varying the rotation speed in the spin coating process in this study. It was confirmed that the thickness of the polyimide alignment layer was controlled according to the spin coating conditions. The average transmittances of anti-parallel LC cells at the spin coating speed of 2,500 rpm and 3,000 rpm are about 60%, which indicates that the LC cell has relatively higher performance. At the spin coating speed of 3,000 rpm, the voltage-transmittance curve of twisted nematic (TN) LC cell was below 1.5 V, which means that the TN LC cell operated at a low power. In addition, high-speed operating characteristics were confirmed with a response time of less than 30 ms. From these derived data, we confirmed that the ideal spin coating speed is 3,000 rpm. And these results provide an optimized polyimide alignment layer process when considering enhanced future LCD manufacturing.

Single Mode Transflective Liquid Crystal Display based on Single Cell Gap without Sub-pixel Separation

  • Du, Tao;Mak, Hin Yu;Xu, Peizhi;Chigrinov, Vladimir;Kwok, Hoi Sing
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.284-287
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    • 2008
  • In this paper, a new Twisted Nematic (TN) transflective liquid crystal display configuration with single cell gap for both transmissive and reflective mode and without sub-pixel separation is proposed. The Transmittance vs. Voltage Curve (TVC) and Reflectance vs. Voltage Curve (RVC) are matched.

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전사배향법을 이용한 씰의 액정배향의 효과 (Effect of Liquid Crystal alignment in the cell using transcription alignment method)

  • 서대식;김진호;최재학
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 1998년도 춘계학술대회 논문집
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    • pp.271-274
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    • 1998
  • In this paper, the monodomain alignment of nematic liquid crystal(NLC) in the cell fabricated by one side transcription alignment method on PI surface with side chain were investigated. The LC alignment produced by the transcription alignment method is attributable to a memory effect of the NLC on Pl surfaces. We observed that the pretilt angle of NLC is generated about 3.6$^{\circ}$ in a cell with one side transcription alignment on PI surface. Also, the electro-optical(EO) performance of TN-LCD with one side transcription alignment method on PI surface will be discussed.

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ATM 망에서 LB와 TJW UPC를 이용한 트래픽 쉐이핑 (Shaping Scheme Using UPC with LB and TJW in ATM Networks)

  • 윤석현
    • 한국컴퓨터정보학회논문지
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    • 제7권3호
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    • pp.143-148
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    • 2002
  • ATM망에서는 예측할 수 없는 트래픽의 변화로 셀 지연과 셀 손실이 발생할 수 있으며 고속의 셀 전송 특성으로 인해 폭주가 발생할 수 있다. 따라서 트래픽 제어는 ATM 망에서 필수적이며, 폭주현상을 줄이기 위한 여러 가지 방법들 가운데 하나가 셀 쉐이핑이다. 본 논문에서는 리키버켓과 TJW로 구성된 셀 쉐이핑 기법을 연구한다. 셀 쉐이퍼는 시간 윈도우를 가진 TJW와 토큰 풀을 가진 리키버켓, 간격제어 버퍼로 구성된다. BONeS시뮬레이터에서 ON/OFF트래픽 소스 모델을 이용하여 제안한 셀 쉐이핑 기법의 성능을 평가한 결과, 패킷화된 음성 트래픽과 고속 트래픽 소스 모두 셀 간격이 평균 비트율에 수렴하여 제어되는 것을 관찰할 수 있었다.

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반사형 TN 액정 셀의 In-Plane스위칭 (In-Plane Switiching of a Twisted-Nematic Reflective LC Cell)

  • 정미준;곽진석;이기동;김재창;윤태훈
    • 한국광학회:학술대회논문집
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    • 한국광학회 2004년도 제15회 정기총회 및 동계학술발표회
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    • pp.138-139
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    • 2004
  • In this paper, we propose a reflective In-Plane Switching twisted nematic mode with negative liquid crystal and weak surface anchoring energy (10$^{-6}$ J/m) in order to enhance reflectance and cellgap margin.

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