• Archives of Pharmacal Research
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• v.27 no.8
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• pp.863-866
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• 2004

The effect of substance P (Sub P) injected intrathecally (I.t.) on c-fos mRNA expression in vari-ous tissues was examined in the present study. We found that a single administration of Sub P(0.5 nM) caused an increase of the c-fos mRNA level in the hypothalamic-pituitary-adrenal(HPA) axis, hippocampus, and spinal cord. The time-course study showed that c-fos mRNA level was maximal at 10 min and began to decrease 30 min after the Sub P injection in all tis-sues, and the Sub P-induced increase of the c-fos mRNA level was returned to the control level 1 h after the injection. The kinetics of the c-fos mRNA expression in mice that were repeatedly injected with Sub P (every 30 min interval up to 4 times) were different in the HPA axis, hippocampus, and spinal cord. The increased c-fos mRNA level in the hypothalamus and the spinal cord induced by I.t. injected Sub P remained at a high level. In the pituitary gland, adrenal gland, and hippocampus, the increased level of c-fos mRNA expression gradually returned to the control level during the repeated substance P injections up to 4 times. Our results suggest that spinally injected Sub P-induced pain stress increases c-fos mRNA expres-sion in the spinal cord, hippocampus, and HPA axis. In mice repeatedly injected with Sub P, the kinetics of c-fos mRNA appear to be different varied from tissue to tissue.

• Journal of Life Science
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• v.8 no.5
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• pp.479-485
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• 1998

The induction of nephric duct from Xenopus presumptive ectoderm(animal cap) was studied and the high-dose ef-fect of IGF-1 was investigated. Activin A induce various organs from cultured animal cap explants and the effects are time and dose-dependent. On the induction of nephric duct, the combined-dose of activin A and retinoic acid was very efficient method in reference study. In present study, we used IGF-1 as well as activin A as a combined growth factor. The concentration ranges of growth factors were activin A l00ng/ml an IGF-1 0-500ng/m1. Explants were cultured in combined solution for 3days to the normal embryo arrives at st. 43. In general, when the explant was cultured in high concentration(l00ng/ml) of activin A, it was destroyed, however, nephric duct and other tis-sues were differentiated by adding IGF-1. In addition, eye induction by adding IGF-1 500ng/ml to activin A 1- 100 ng/ml solution was studied. The low concentration of activin A(1ng/ml) have blood-like cell inducing effect and the explant was balloon-shaped, however, the high dose combination with IGF-1 extended the range of eye inductive concentration of activin A.

• Journal of Chest Surgery
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• v.29 no.6
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• pp.632-638
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• 1996

A retrospective analysis of primary mediastinal tumors and cysts was performed on 42 patients who underwent surgical resection at our institution from january, 1985 to December, 1995. The patients consisted of 27 males and 15 females. The mean age was 40 years with a range of 10 month to 76 years. The patients were composed of thymlc tumor 12 cases (28.6 %), germ cell tumor 8 cases (19.0 %), primary cyst 7 cases (16.7 %), neurogenic tumor 6 cases (14.3 %) and other miscellanious tumor 9 cases. Overall, 3) (78.6 %) of the tumors were histologically benign, and 9 (21.4 %) were malig- nant. The noted clinical manifestations were respiratory symptoms such as chest pain, dyspnea and coughing. All of the patients with malignancy and 55 oyo of the patients with benign tumor were symptomatic on presentation. All of the patients were operated for tis ue diagnosis and curative resection. All the benign tumors ex- cept two cases of sarcoidosis were performed adequate curative resection. A few patients with malignant unresectable tumors were treated with chemotherapy or radiotherapy There were 7 (18 %) postoperative complications without mortality. In conclusion, Mediastinal tumors have long fascinated the thoracic surgeon because of their variety and unpredictability of diagnosis prior to exploration. We consider that active surgery and various combined modality can be accomplished with satisfactory result.

• Korean journal of applied entomology
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• v.39 no.1
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• pp.53-58
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• 2000

The effect of NeemAzal-T/S was tested by leaf disk method on fecundity, egg mortality, and preference of twospotted spider mite, Tetranychus urticae and its predator mite, Amblyseius womersleyi in the laboratory. Mortalities of T. urticae and A. womersleyi adults were 97.7% and 20.0%, in 100ppm treatment at 72 h after application, respectively. The mean number of eggs laid per T. urticae female adult were 0.0 and 18.5, and those of A. womersleyi were 1.6 and 2.9 at 100 ppm and 0 ppm concentrations, respectively. Hatchability of T. urticae eggs treated with 50 and 100 ppm were 52.8%, and 2.5%, respectively, and those of A. womersleyi eggs were 100% and 91.3%, respectively. Choice and no-choice tests revealed that T. urticae female preferred to alight and oviposit on untreated bean leaf disk with 13.8 to 18.2 eggs per female. In contrast, A. womersleyi female preferred on treated or untreated bean leaf equally. There was no significant differences in the number of consumption of T. urticae eggs by A. womersleyi on treated and untreated bean leaves, except 200 ppm. These results indicate that NeemAzal-TIS is highly toxic to T. urticae, and is less toxic to A. womersleyi. It may be concluded with these results that NeemAzal-T/S could be incorporated into integrated T. urticae management system.

• Journal of the Korean Chemical Society
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• v.56 no.3
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• pp.363-370
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• 2012

The purpose of the study was to classify scientific models in the seventh grade science textbooks of the 2007 revised science curriculum. The three chapters of 'three states of material', 'motion of molecule', and 'change of state and energy' were investigated. There were two types of the scientific model as 'mode of representation' and 'attribute of representation'. The mode of representation was composed of 'action model', 'analogical model', 'symbolic model', and 'theoretical model' and the attribute of representation was composed of 'static model' and 'dynamic model'. The results showed that the action model and the analogical model were used primarily in mode of representation. The dynamic model were widely used in attribute of representation. Area of matters dealt with conception of molecules and aimed for students to understand the arrangement and movement of molecule microscopically about macroscopic state in a daily life. Tis study could help to recognize the limitations of scientific models on current textbooks and offer more useful information in planning lessons and organizing textbooks for the future.

• Water for future
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• v.14 no.4
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• pp.35-52
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• 1981

This study is to evaluate the areal precipitation from the basic data groups of monthly, seasonal, and annual rainfalls over all ma in stations in Korea. The evaluating pocesses are performed through the point and regional frequency analysis from the basic data. The basic data groups are divided into two periods-the first(1916-1944) and the second (1960-1979)-which are compared with each other. In the point frequecny analysis, the variable transformation method is applied to the best fitting distribution, and the normal fittings are established by using the Chisquare test method. In the regional frequency analysis, the geomorphologic factors and hydrometeorological factors are taken into consideration when dividing into five zones and Thiessen method and the Isohyetal method are applied. The results of this study are as follows: 1)The areal precipitation values of the first period are about 70-80mm less than that of the second period for the whole of Korea. Therefore, a new precipitation value of 1180mm is considered more suitable than the value of 1159mm, which has been up till now. 2)As the annual areal precipitiation values areevaluated over the five divide zones, it tis noticed that the difference between the values of the first period and the second is the largest in spring (to the extent of 5 times that in the other seasonas). Thereform it is considered that this result is necessary for the establishment of a timely insurance plan for the water resources. 3)The application of the Isohyetal method through the division of Korea into five zones is considered to be a reasonable procedure in the analysis of areal precipitation.

• KIPS Transactions on Computer and Communication Systems
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• v.1 no.2
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• pp.61-70
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• 2012

In this study we evaluate usefulness of InSciTe Advanced, technology opportunity service offering trends information related technologies by analyzing automatically large amount of data. Before developing the service, InSciTe Advanced, we design 5 main services - Trends and Predictions, Technology Levels, Relationship Paths, Roadmaps, Competitors and Collaborators - through the interviews with expert in planning R&D strategy. And we evaluate usefulness of each service in InSciTe Advanced to examine how the information analyzed by InSciTe Advanced are useful to user from two points of view, Satisfaction of Information and Completeness of Information. Users set a high value on 5 main services in all tis aspects, but give relative low grades to completeness of Information. We will learn lessons from this study, increase kinds and amount of data, and strengthen the process about accuracy and reliability of analyzed information from the service.

• Journal of radiological science and technology
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• v.25 no.2
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• pp.57-64
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• 2002

The recent development of embodiment technology of the medical images makes most medical institutions introduce PACS(Picture Archiving and Communication System) in haste. However lots of PACS solutions, currently developed and distributed, haven't been able to serve the convenience of users and to satisfy user's demand because of economic limitations and administrator-oriented considerations in the process of development. So we have developed MIH(Medical Image History), by which we can search and refer to the patient's medical images and information with few restrictions of time and space for diagnosis and treatment. This program will contribute to the improvement in the medical environment and meet the clients' need. We'll make more effort to develop the application which insures the better quality of medical images. MIH manages the patient's image files and medical records like film chart in connection with time. This trial will contribute to the reduction of the economical loss caused by unnecessary references and improve the quality in the medical services. The demand on the development or the program which refers to the medical +ata quickly and keeps them stable will be continued by the medical institute. This will satisfy the client's demand and improve the service to the patients in that tile program will be modified from the standpoint of the users. MIH is trying to keep user-oriented policy and to apply the benefit of the analog system to the digital environment. It is necessary to lead the public to the better understanding that the systematic management and referring of the medical images is as important as the quality of the images.

• Maritime Security
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• v.4 no.1
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• pp.115-138
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• 2022

The Korean military is preparing for successful manpower reduction using advanced science and technology, in addition to carrying out the initiative of the Defense Innovation 4.0. Accordingly, studies on core technologies related to defense reform have been conducted both internally and externally in the military, and the corresponding results have also been applied. Nevertheless, compared to the development of such technologies, it is considered necessary to have more preparation for the policies related to the operation of the newly introduced equipment. As for the placement of personnel and the organization of time in service (TIS) with respect to the operation of surveillance equipment, there has been a tendency to sustain the conventional practice. Therefore, this study intends to suggest the schemes for facilitating policy improvements in the operation of manpower and security regulations in the field of information for the purpose of introducing a successful next-generation coastal guard system. To do this, the approach of this study was focused on the policies for the operation of the guard system. This is in contrast to previous studies that centered on its equipment and technologies. In addition, how to efficiently operate the guard system was also studied in view of cognitive science by deriving the most efficient time for a person to execute surveillance through the monitor based on the previous studies.

• Korean Journal of Materials Research
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• v.34 no.1
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• pp.1-11
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• 2024

This research investigated the preparation of activated carbon derived from Krabok (Irvingia malayana) seed shells to improve the quality of crude glycerol obtained during biodiesel production. The activated carbon was prepared using a dry chemical activation method with NaOH, utilizing an innovative biomass incinerator. The results revealed that the resulting KC/AC-two-step exhibited favorable physicochemical adsorption properties, with a high surface area of 758.72 m²/g and an iodine number of 611.10 mg/g. These values meet the criteria of the industrial product standard for activated carbon No. TIS 900-2004, as specified by the Ministry of Industry in Thailand. Additionally, the adsorption efficiency for methylene blue reached an impressive 99.35 %. This developed activated carbon was then used to improve the quality of crude glycerol obtained from biodiesel production. The experimental results showed that the KC/AC-two-step increased the purity of crude glycerol to 73.61 %. In comparison, commercially available activated carbon (C/AC) resulted in a higher crude glycerol purity of 81.19 %, as analyzed by the GC technique. Additionally, the metal content (Zn, Cu, Fe, Pb, Cd, and Na) in purified glycerol using KC/AC-two-step was below the standards for heavy metals permitted in food and cosmeceuticals by the Food and Drug Administration of Thailand and the European Committee for Food Contact Materials and Articles. As a result, it can be inferred that Krabok seed shells have favorable properties for producing activated carbon suitable as an adsorbent to enhance crude glycerol purity. Furthermore, the improved crude glycerol from this research has potential for various industrial applications.