• Nutritional Sciences
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• v.1 no.1
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• pp.70-76
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• 1998

This study was designed to investigate the relationship between body mass index (BMI) and dietary intake, and the relationship between BMI and plasma lipid levels in Korean adults. This study was conducted from January 1 to December 31 of 1997. It consisted of 3781 subjects (men 2402, women : 1379) with the majority between the ages of 40 and 59. The dietary assessment was based upon a twenty-four-hour food record. Subjects were classified into one of four reference BMI groups : underweight ($\leq 20 kg/m^2$), normal (20.1-25.0 kg/$m^2$), overweight (25.1-30.0 kg/$m^2$), and obese (>30 kg/$m^2$). The biochemical assessment included measurements of plasma total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglyceride (TG), lipoprotein (a), and plasminogen activator inhibitor-1 (PAI-1). The BMI study showed that 60.5% of the men measured were normal and 32.6% of the men were overweight and/or obese subjects. Sixty-four percent of the women were normal and 20.3% of the women measured were overweight and/o. obese subjects. With respect to the daily energy intake of the men and women subjects, the levels of daily energy intake appeared to increase as values of BMI increased. Men of the overweight group had significantly higher protein, fat and cholesterol intake than those of the normal or the underweight groups. The alcohol intake of the men in the overweight group was also significantly higher than that of the men in the underweight group. With respect to percent energy intake of macronutrients, there was no significant difference between the four BMI groups and percent energy intake for all the subjects in the study. The ratio of percent energy intake of carbohydrates : protein : fat : alcohol of the normal women group was 62 : 17 : 20 : 1, respectively. Women apparently had a higher intake of carbohydrates than men (52 : 17 : 19 : 10). With respect to the levels of plasma TC, LDL-C, TG, and HDL-C, the levels of plasma TC, LDL-C and TC appeared to increase as the values of BMI increased, while the level of HDL-C appeared to decrease as values of BMI increased. Levels of lipoprotein (a) appeared to be inversely related to the values of BMI, and levels of PAI-1 appeared to increase as values of BMI increased. The results of this study demonstrate that there is a relationship between dietary intake and BMI, and that there is a relationship between BMI and blood lipids levels.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.5
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• pp.1164-1171
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• 1999

In this study, we investigated the effects of obesity index on the risk factors of chronic diseases in obese children. The subjects were male and female children aged 9 to 12. The average obesity index was 147.7$\pm$13.8% in boys and 147.6$\pm$16.5% in girls. The average percentages of body fat was significantly higher in boys(33.9$\pm$5.7%) than in girls(30.7$\pm$4.4%). It was found that 26% of subjects had abnormal serum GOT and GPT values. Percentages of subjects at risk of cardiovascular disease(CVD) based on corresponding criteria of TG, T chol, HDL chol, and LDL chol were 28.6%, 28.6%, 45.5% and 42.7%, respectively. The risk of CVD was increased with the degree of obesity, which was not significant. The AI(atherogenic index) was higher in boys(4.6$\pm$2.3) than in girls(3.6$\pm$1.2). The serum T chol and LDL chol levels of subjects whose mother are in thirties were significantly higher than those of subjects whose mother are in fourties. The T chol levels of subjects who had mother with job were significantly higher compaired to those of subjects who had housewife mother. The results indicated the urgent need of nu tritional management for the obese children to prevent further devel opment of childhood obesity and hyperlipidemia. Based upon this study, devising method and media for the mother nutritional education as well as for the children nutritional education is required for better growth and health promotion of primary school children.

• Nutrition Research and Practice
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• v.8 no.4
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• pp.469-475
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• 2014

BACKGROUND/OBJECTIVE: The goal of the present study was to investigate the effects of moderate caloric restriction on ${\beta}$-cell function and insulin sensitivity in middle-aged obese Korean women. SUBJECTS/METHODS: Fifty-seven obese pre-menopausal Korean women participated in a 12-week calorie restriction program. Data on total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), and fasting serum levels of glucose, insulin, C-peptide, blood pressure, leptin and anthropometrics were collected. A dietary intake assessment was based on three days of food recording. Additionally, ${\beta}$-cell function [homeostasis model assessment of ${\beta}$-cell (HOMA-${\beta}$), insulinogenic index (ISI), C-peptide:glucose ratio, and area under curve insulin/glucose ($AUC_{ins/glu}$)] and insulin sensitivity [homeostasis model assessment for insulin resistance (HOMA-IR), Quantitative insulin-sensitivity check index (QUICKI) and Matsuda index (MI)] were recorded. RESULTS: When calories were reduced by an average of 422 kcal/day for 12 weeks, BMI (-2.7%), body fat mass (-10.2%), and waist circumference (-5%) all decreased significantly (P < 0.05). After calorie restriction, weight, body fat percentage, hip circumference, BP, TC, HDL-C, LDL-C, plasma glucose at fasting, insulin at fasting and 120 min, $AUC_{glu}$ and the insulin area under the curve all decreased significantly (all P < 0.05), while insulin sensitivity (HOMA-IR, QUICKI and Matsuda index) measured by OGTT improved significantly (P < 0.01). CONCLUSIONS: Moderate weight loss due to caloric restriction with reduction in insulin resistance improves glucose tolerance and insulin sensitivity in middle-aged obese women and thereby may help prevent the development of type 2 diabetes mellitus.

• 한국노년학
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• v.29 no.3
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• pp.823-835
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• 2009

This study was designed to examine the effects of 12 weeks of circuit exercise on obesity, physical fitness and metabolic syndrome index in elderly obese women. 19 elderly obese women volunteered to participate in and completed the study. Participants went through their exercise program for 30 minutes per session and 3 sessions per week for 12 weeks. Lower(p<.001) and upper extremities strength(p<.05), upper(p<.05) and lower extremities flexibility(p<.01), agility & dynamic balance(p<.001), endurance exercise capacity(p<.05) were significantly increased after 12 weeks circuit training. Also, Body weight(p<.001), BMI(p<.001) & Metabolic syndrome index as waist circumference(p<.01), systolic BP(p<.05), TG(p<.001), HDL-C(p<.01), glucose(p<.05) were significantly differenced between pre and post. It was concluded that circuit exercise program has positive effects on body composition, physical fitness and metabolic syndrome index in elderly obese women.

• Journal of the Korean Society of Food Culture
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• v.16 no.2
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• pp.89-98
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• 2001

The purpose of this study was to investigate the effects of body weight control program for obese children. The program included nutrition education, exercise and behavioral therapy for 20 weekly sessions. The results from this study were as follows. The average age of the subjects was 11.3 years, mean height and weight were 146.12cm and 59.42kg respectively. After weight control preogram, Rohrer index(Rl) was significantly decreased from 186.78 to 182.72(p<0.001). There were not significant differences in body fat percent(%) and fat weight(kg) but it showed decreased pattern. In the change of body circumferences, chest circumference was significantly increased(p<0.01) and mid-arm circumference was significantly decreased(p<0.001) after weight control program. Triglyceride(TG) level in serum was significantly decreased from 113.79 to 80.36(p<0.01) and total cholesterol and LDL-cholesterol level showed declind pattern. The food habits of obese children significantly improved(p<0.001) after weight control prgram. And there were desirable changes of food attitude, excercise and life habits. These results suggest that weight control program including nutrition education, exercise and behavioral therapy may be effective for helping obese children.

• Journal of the Korean Society of Safety
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• v.25 no.3
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• pp.45-52
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• 2010

The purpose of this study is application to flame retardant powder coating(FRPC) material consisting of ammonium polyphosphate(APP) and magnesium hydroxide($Mg(OH)_2$) as a halogen free flame retardant into thermoplastic resin(LDPE-g-MAH). For improvement of adhesion, LDPE-g-MAH was synthesized from low density polyethylene(LDPE) and maleic anhydride(MAH). The mechanical properties as melt flow index, pencil hardness, cross-hatch adhesion and impact resistance of FRPC were measured. Also, the limited oxygen index(LOI) values were measured 17.3vol%, 31.1vol% and 33.7vol% for LDPE-g-MAH, FRPC-3(APP 15wt%, $Mg(OH)_2$ 15wt%) and FRPC-5(APP 30 wt%), respectively. The thermo gravimetry/differential thermal analysis(TG/DTA) of FPRC-3 was observed endothermic peak at $340^{\circ}C$ and $450^{\circ}C$, it was confirmed predominant thermal stability though the wide temperature range by APP and $Mg(OH)_2$. It was showed V-0 grade for FRPC-3 and FRPC-4(APP 20wt%, $Mg(OH)_2$ 10wt%) that a char formation and drip suppressing effect, and combustion time reduced by UL94(vertical burning test). It was confirmed that flame retardancy was improved with the synergy effect because of char formation by APP and $Mg(OH)_2$.

• Journal of Nutrition and Health
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• v.36 no.3
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• pp.245-254
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• 2003

The aim of this study was to investigate the effects of P/S ratio of fatty acid and antioxidant (vitamin E, selenium) supplements on the serum lipid levels and hepatic antioxidant enzyme activity in rats. Female 16-week-old Sprague-Dawley rats were fed 6 different experimental diets for 4 weeks. While the peroxidizability index (PI) levels of fatty acids in the experimental diets were fixed at 81.22, the levels of P/S ratio of fatty acids were formulated at 0.38, 1.00, 4.81 (LP, MP, HP). These diets were supplemented with vitamin E (1,000 mg/kg diet) and selenium (2.5 mg/kg diet) (LP-S, MP-S, HP-S). This study showed that the serum concentrations of total-cholesterol and HDL-C increased with the increasing of the P/S ratio in the diet (p <0.05). Antioxidant supplementation significantly lowered the concentrations of triglyceride (TG) and VLDL-C of serum (p<0.05). Levels of thiobarbituric acid reactive substance (TBARS) in the liver tended to decrease with the increasing of the P/S ratio in the diet (p<0.001), but antioxidant enzyme activity in the liver was not significantly different. In addition, antioxidant supplementation significantly lowered TBARS level in the liver (p<0.05), but had no effect on antioxidant enzyme activity except for glutathione reductase (p<0.05). In conclusion, it is necessary to consider the properties of dietary fatty acids and antioxidants supplementation for the prevention of cardiovascular diseases.

• Nutrition Research and Practice
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• v.1 no.1
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• pp.14-18
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• 2007

This study investigated the effect of physical training and oxidative stress on the anti oxidative activity and on plasma lipid profile. Forty eight rats were given either a physical training or no training for 4 weeks and were then subdivided into 3 groups: before-exercise (BE); during-exercise (DE); after-exercise (AE). The antioxidative activity was evaluated with the activities of catalase in plasma and superoxide dismutase (SOD), the ratio of reduced glutathione/ oxidized glutathione (GSH/GSSG) and the level of malondialdehyde (MDA) in liver. The plasma concentrations of triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C)) were also compared. Compared to those of non-training group. catalase activities of training group were lower before exercise but higher during and after exercise. SOD activities were higher regardless of exercise. GSH/GSSG ratio was higher before exercise but was not significantly different during exercise and even lower after exercise. There were no differences between non-training group and training group in MDA levels regardless of exercise. Compared to those of non-training group, atherosclerotic index of training group was lower after exercise and there were no significant differences before and during exercise. There were no differences between non-training group and training group in HDL-C regardless of exercise. These results suggest that moderate physical training can activate antioxidant defenses and decrease the atherosclerotic index and this beneficial effect is evident under exercise-induced oxidative stress.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.1
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• pp.11-20
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• 1996

본 조사는 경기도 용인에 위치한 명지대학교의 남녀 대학생 202명의 대상으로 일반 환경과 혈철지질, 혈압, 체지방량 측정 검사를 중심으로 이루어졌으며, 조사 분석한 결과를 요약하면 다음과 같다. 1. 조사 대상자의 신체발달 상황을 보면 남자의 평균 신장과 체중 및 비체중치는 173.1cm, 65.9kg, 38.03이였고, 여자는 16.7cm, 52.4kg, 32.6로 한국인 성인의 표준치와 매우 유사한 수치였다. 체지방량 비율은 남자 16.4, 여자 24.0으로 나타 설별에 따른 차이가 뚜렸하였다. 2, 조사 대상자들의 수축기와 이완기의 혈압은 평균 $125\pm123mmHg,$ $77.2\pm11.1mmHg이고,$ 남자와 여자의 수축기 혈압은 각각 $132.3\pm1.9mmHg,$ $118.1\pm1.6mmhg로$ 정상 범위였다.확장기 혈압은 남녀 각각 $80.5\pm11.0mmHgm$ $73.9\pm102.m,Hg였으며$ 역시 정상범위에 포함되었다. 3. 혈청 지질의 검사 결과는 Tc는 남자 175.2mg/dl, 여자 183.6mg/dl로 나타났고 TG는 남자 108.4mg/dl, 여자 72.0mg/dl로 나타나 통RP적으로 유의한 차이가 있었다. (p<0.05). 또한 HDL-C는 남자 59.6mg/dl , 여자 64.3mg/dl 로 성별에 다른 유의적인 차이를 보였고 (p<0.05), LDL-C도 역시 남자 93.9mg/dl, 여자 104.8mg/dl로 나타나 통계적으로 성별에 다른 차이가 뚜렷하였다. (p<0.01). 조사결과 다른 연령층의 성인과는 달리 TG를 제외한 TC, H이-C, L이-C에 있어서 남자가 여자 보다 더 낮은 수치를 보였다. 4. 혈압에 따라 세 그룹으로 분류한 후 혈청 지질과의 관계를 보면, 수축기 혈아이 증가함에 따라 TC, TG, LDL-C은 증가하는 경향을 보였으며, HDL-C은 감소되었으나 통계적으인 유의성은 없었다. 이완기혈압의 겨우 89mmHg 이하 보다 90~94mmHg의 경우에 유의적으로 증가되었으며 (p<0.05) HDL-C은 감소하였으나 유의성은 없었다. 5. 혈정 지질과 비만도의 관계는 남녀 모두 양의 상관관계를 나타냈으나 여자보다 남자에서 뚜fut이 나타났다. 남자의 겨우 TC의 수치가 KI에 따라 110% 미만일 때 $169.7\pm31.5mg/dl,$ 110~120%일 때 $193.8\pm36.8mg/dl,$ 120% 이상 일 때 $202.2\pm29.3mg/dl로$ 비만도에 따른 유의적인 증가를 (p<0.05)보여주었으나 여자의 경우는 유의적인 차이가 없었다. TG의 수치는 남자의 경우 KI가 110%미만인 그룹은 $102.9\pm108.2mg/dl,$ 120% 이상인 그룹은 $112.2\pm40.0mg/dl로$ 비만도가 증가함에 따라 TG가 증가되었으나 유의적인 차이는 없었으며, 여자의 경우 유의적인 차이가 없었다. 남자의 경우 HDL-C은 비만도가 증가함에 따라 유의적으로 감소하는 경향을 보였으나(p<0.05) 여자의 경우는 유의적인 차이가 없었다. 6. 조사 대상자의 체지방량 측정결과 체기방률은 남자의 겨우 16.4% 여자의 겨우 24.0%로 나타나 여자의 체지방률이 남자보다 높았다. 7. 신체계측치, 혈압, 혈청 지질간의 상관관계를 살펴보면 TC, TG는 KI, BMI와 유의적인 양의 상관관계를 보였고 (p<0.01), HCL-C은 비체중, BMI, LBM, TBM와 유의적인 음의 상관관계를 보였으며, (p<0.01), KI, SBP와도 음의 상관관계를 보였다. (p<0.05), LCL-C는 KI와 유의적이인 양의 상관관계를 나타내었으며 (p<0.01) BF%, TBF, BMI와도 양의 상관관계를 나타냈었다. (p<0.05). 또한 LPH, Al는 모두 나이, 비체중, BMI, KI와 유의적인 양의 상관관계를 나타내었다. (p<0.01). 이상을 종합해 보면 본 조사 대상자들은 비만도가 높아질수록 혈청 지질 수준이 놓았으며, 이완기 혈압도 형철 지질과 상관관계를 나타났다. 대학생의 혈청 지질과 체지방에 대한 자료가 부족함을 고려할 때, 본 조사자료가 학생의 혈청지질의 체지방에 대한 기초 자료로서 이용될 것을 기대하며 보다 다각적인 연구가 이루어지기를 바라는 바이다.

• Food Science of Animal Resources
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• v.31 no.2
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• pp.250-256
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• 2011

This study was conducted to evaluate the effect of whole egg supplementation on the blood lipid profiles and cholesterol levels of C57BL/6 mice. Sixty-six mice were divided into two groups: normal-diet supplemented and high-cholesterol diet supplemented. Lyophilized whole egg powder was mixed with the two diets at 2 and 10%: normal diet only, normal diet with 2 and 10% whole egg powder, high cholesterol diet only, high cholesterol diet with 2 and 10% whole egg powder. The mixed diets were fed for 5 wk and feeding condition (body weight change, feed intake, and feed efficiency ratio (FER)), blood lipid profiles (total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein cholesterol, hepatic and fecal lipids (TG, TC)), and fecal bile acids were determined. No significant differences were found in body weight gain or FER after whole egg supplementation in both the normal and high-cholesterol diet fed groups. In the normal-diet fed mice, HDL-C increased significantly in the 2 and 10% whole-egg powder groups. In the high-cholesterol diet fed mice, administering 10% egg powder increased the atherogenic index compared to the control. Furthermore, administration of whole egg powder increased fecal bile acids dose dependently (p<0.05). These results indicate that administering 2% hen whole egg powder did not affect blood lipid profiles and was more beneficial for health by increasing HDL-C and aiding in the excretion of cholesterol by fecal bile acids than those in the control.