• 한국학교보건학회지
• /
• 제34권2호
• /
• pp.87-97
• /
• 2021

Purpose: The authors used a meta-analysis approach to investigate the effects of exercise on gender-specific triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) in obese adolescents. Methods: This study is a systematic review and meta-analysis study to confirm the effect of exercise intervention according to gender for obese adolescents. PICO were obese a adolescents, exercise intervention, comparative intervention (control and general group),TG and HDL-C. Results: The group of obese male adolescents showed a statistically significant decrease of 51.72 in TG (n=175, MD=-51.72; 95% CI -52.44 to -51.00).There was a statistically significant increase of 4.44 in HDL-C (n=175, MD=4.44; 95% CI 3.79 to 5.10) in the group of obese male adolescents. Conclusion: Triglyceride and high-density lipoprotein cholesterol were analyzed to determine the effect of exercise interventions in obese adolescents according to gender differences. The results of this study can be used as basic data for the design of future exercise intervention studies, subjects, exercise methods, and intervention periods.

• Journal of Nutrition and Health
• /
• 제38권2호
• /
• pp.144-150
• /
• 2005

The aim of this study was to analyze an association between milk consumption and serum lipid profiles in postmenopausal women in Korea. The dietary data by the Food Frequency Questionnaire were evaluated among 208 postmenopausal women who did not receive hormone therapy and their serum concentrations of triglyceride (TG), total, HDL-, and LDL-cholesterol, and alkaline phosphatase were analyzed. When the relationship between milk consumption and serum lipid profiles were analysed by linear regression, we found a negative relationship of milk consumption with ALP and a positive relationship with HDL-cholesterol. Animal calcium intake was significantly correlated with ALP and HDL-cholesterol. In addition, the serum level of HDL-cholesterol of the upper quartile (UQ) subjects who took animal calcium over 313 mg/day was significantly higher than the lower quartile (LQ) subjects who consumed milk below 101 mg/day when we compared the UQ and LQ subjects. The HDL-cholesterol level of the UQ subjects who consumed 235 ml of milk tended to be higher than the that of the LQ who consumed 53 ml. As for serum concentrations of TG, total cholesterol, and LDL-cholesterol, there was no significant difference between the UQ and LQ groups of milk consumption. Based on our study, we concluded that continual consumption of approximately one cup of milk per day was associated with low cardiovascular risks with favorable lipid profiles and ALP in postmenopausal women. (Korean J Nutrition 38(2): 144～150, 2005)

• 대한방사선기술학회지:방사선기술과학
• /
• 제31권1호
• /
• pp.33-39
• /
• 2008

복부비만은 2형 당뇨병과 고지혈증, 고혈압, 관상동맥질환 등의 심혈관계 질환의 주요 위험인자이며 특히 내장형 복부 비만인 경우 위험도가 더 크다고 알려져 있다. 이 연구에서는 2006년 4월부터 2007년 9월까지 일개 대학병원 비만 클리닉을 방문한 BMI 23 이상의 성인 여성 25명을 대상으로 하여 복부지방 CT를 실시하여 지질대사지표와의 상관성 및 내장지방 분포에 영향을 주는 요인을 분석하였다. 8시간 공복 후 채취한 정맥혈액을 이용하여 Glucose, TC, TG, HDL의 농도를 분석하였고, 안정시의 이완기 혈압과 수축기 혈압을 측정하였다. 연구결과 내장지방량은 TC와 TC/HDL과 음의 상관관계를 보였다. 통계적으로는 BMI, TAF, VSR이 통계적으로 유의한 차이가 있는 것으로 나타났다(p < .001). 내장지방량을 가장 잘 반영하는 지질대사지표는 TC와 TG, HDL인 것으로 나타났으며, 이 회기분석모델은 47%의 설명도를 가지고 있는 것으로 나타났다.

• 한국콘텐츠학회논문지
• /
• 제10권8호
• /
• pp.301-307
• /
• 2010

비만을 평가하기 위한 방법들은 다양하며 현재 임상에서 가장 많이 사용하고 있는 것은 BMI와 BIA를 이용한 %Fat방법이다. 이 연구에서는 비만과 밀접한 관련이 있는 고지혈증을 진단함에 있어 BMI와 %Fat의 예측능력에 차이가 있는지를 알아보고자 하였다. 총 224명의 성인여성을 대상으로 하여 신체계측을 시행하였고, BIA를 통해 %Fat을 측정하였다. 공복상태에서 채혈을 실시하여 TC, TG, HDL을 측정하였으며, LDL은 Friedwald의 공식을 이용하여 산출하였다. AI는 TC를 HDL로 나눈 값으로 정의하였다. 연구결과 혈중지질은 BMI와 %Fat이 증가함에 따라 HDL은 감소하고 TC, TG, LDL, AI는 증가하는 것으로 나타났다. BMI와 %Fat사이에는 r=.585의 상관관계가 있는 것으로 나타났으며 BMI가 %Fat에 비해 혈중지질과의 상관도가 더 높은 것으로 나타났다. 결론적으로 성인여성을 대상으로 BMI를 이용하여 혈중지질을 예측하고 분류하는 것에 큰 무리가 없을 것으로 판단되나, 가장 바람직한 방법은 BMI와 %Fat 기준을 혼용하여 혈중지질을 평가하는 것이라 생각되어진다.

• 동의생리병리학회지
• /
• 제22권3호
• /
• pp.607-611
• /
• 2008

Lipopolysaccharide (LPS) induces the synthesis of several inflammatory cytokine, chemokine, NO and inflammation in the liver of rats. The purpose of this study was to investigate the preventive effects of Houttuynia cordata Thunb and Oriental herbs mixture extract (HCTM) against the hepatotoxicity-inducing LPS in the lipid metabolism. HCTM of 100 mg/kg concentration was intra-peritoneally administered into rats at dose of 1.5 ml/kg for 20 days. On the day 21, 1.5 ml/kg of LPS was injected 4 hours before anesthetization. The levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), total lipid, triglyceride (TG) and HDL-cholesterol (HDL-C) were measured in serum. LPS-treatment markedly increased the levels of GOT, GPT, total lipid and TG, and decreased the level of HDL-C. However, HCTM pretreatment decreased the levels of GOT, GPT, total lipid and TG by 76.8%, 55.48%, 34.04% and 76.21% respectively, and increased the level of HDL-C by 97.84%. These results showed that HCTM had the protective effect against the hepatotoxicity-inducing LPS in the lipid metabolism, and it suggest that HCTM could be used for functional beverage.

• 한국직업건강간호학회지
• /
• 제23권2호
• /
• pp.97-105
• /
• 2014

Purpose: The purpose of this study was to identify the link between health-related physical fitness level and cardiovascular disease-related risk factors in adult male workers. Methods: We tested cardiovascular disease-related risk factors (waist circumference, SBP, DPB, fasting glucose, TC, HDL-C, TG, LDL-C) and health-related physical fitness ($VO_2max$, grip, Sit-up, Flexibility, Body fat) and divided health-related physical fitness level of the subjects into 3 groups - A (very good, n=56), B (good, n=59), and C (below-average, n=57) according to the criterion of the Health and Fitness counseling guidelines of KOSHA. The statistical techniques such as standard deviation, one-way ANOVA and multiple regression (p<.05) were used. Results: There were significant differences between group C and group B & A (p<.001) in waist circumference, DBP, Fasting glucose, HDL-C, TG, LDL-C. In TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Group C was higher than group B and A. Conclusion: On the basis of these results, we identified that improvement of health-related physical fitness level positively effects on the decrease of cardiovascular disease-related risk factors.

• 대한지역사회영양학회지
• /
• 제28권5호
• /
• pp.404-413
• /
• 2023

Objectives: This study compared serum lipid concentration according to drinking habits. Methods: We analyzed data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII). The study included 8,525 adults (3,651 males and 4,874 females), aged 30 - 59 years. Results: There were differences in age, gender, education level, smoking status, physical activity, and waist circumference between drinkers and abstainers. The serum low-density lipoprotein-cholesterol (LDL-C) level of the drinkers was lower than those of the abstainers (P < 0.05). The serum triglyceride (TG) and high-density lipoprotein-cholesterol (HDL-C) concentrations were highest in the group that consumed alcohol 'more than twice a week' relative to the other groups (P < 0.001). The LDL-C and atherogenic index (AI) levels were lowest in the 'more than twice a week' drinking group compared to the other groups (P < 0.001). The serum TG and HDL-C concentrations were the highest in the '7 glasses/time' group (P < 0.001). The serum LDL-C concentration was the lowest in the '7 glasses/time' group (P < 0.001). Notably, the higher the frequency of binge drinking (7 glasses or more), the higher the concentration of TG (P < 0.001). The serum HDL-C concentration was significantly higher in the 'no binge' and 'more than once a week' groups compared to the other groups (P < 0.001). The serum LDL-C concentration and AI score were the lowest in the 'more than once a week' group (P < 0.001). Conclusions: As the quantity and frequency of drinking increased, the serum TC concentration increased. Moreover, an increase in the serum HDL-C concentration led to a decrease in AI. The factors exacerbating cardiovascular disease increased simultaneously due to drinking. Our results suggest that for individuals with hypertriglyceridemia and patients with low HDL-cholesterolemia, separate guidelines based on the quantity and frequency of alcohol consumption are warranted.

• 정신신체의학
• /
• 제25권1호
• /
• pp.27-32
• /
• 2017

연구목적 본 연구는 우울 증상과 혈중 콜레스테롤 농도의 연관성이 성별에 따라 차이가 있는지 살펴보고자 하였다. 방법 건강검진을 받은 일반인 중 27,452명(남자 15,044명, 여성 12,408명)을 대상으로 후향적 의무기록 조사를 통하여 이루어졌다. 대상자들의 벡우울척도(Beck Depression Inventory, BDI)점수를 구하고 총콜레스테롤(Total cholesterol, TC), 중성지방(Triglyceride, TG)), 고밀도 지단백 콜레스테롤(High density lipoprotein cholesterol, HDL-C), 저밀도 지단백 콜레스테롤(Low density lipoprotein cholesterol, LDL-C)을 분석하였다. 결과 남성은 총콜레스테롤(TC)과 벡우울척도(BDI) 점수 사이에는 통계적으로 유의한 상관성을 보이지 않았다. 중성지방(TG)은 벡우울척도(BDI) 점수와 양의 상관성을 보였으며(r=0.020, p<0.01), 고밀도 지단백 콜레스테롤(HDL-C)와 저밀도 지단백 콜레스테롤(LDL-C)은 벡우울척도(BDI) 점수와 음의 상관성을 보였다(r=-0.016, p<0.01 ; r=-0.015, p<0.05) 여성의 경우도 총콜레스테롤(TC)과 벡우울척도(BDI) 점수 사이에는 통계적으로 유의한 상관성이 없었으며 중성지방(TG)은 벡우울척도(BDI)점수와 양의 상관성을 보였고(r=0.020, p<0.01) 고밀도 지단백 콜레스테롤(HDL-C)과는 음의 상관성을 보였다(r=-0.019, p<0.01). 남성과 달리 저밀도 지단백 콜레스테롤(LDL-C)은 통계적으로 유의한 상관성을 보이지 않았다. 결론 남녀 모두 중성지방(TG)이 높을수록, 고밀도 지단백 콜레스테롤(HDL-C)이 낮을수록 우울 증상의 정도가 심한 것으로 나타났으며, 남성에서만 저밀도 지단백 콜레스테롤(LDL-C)이 낮을수록 우울 증상이 심한 것으로 나타났다.

• 한국식품위생안전성학회지
• /
• 제12권1호
• /
• pp.83-95
• /
• 1997

This study showed the effect of fermented milk on the cholesterol level of Korean. 130 persons among the teachers of elementary, middle and high schools, professors and graduate school students were divided into two groups according to their cholesterol level and provided with fermented milk 300 $m\ell$ dairly from Sep.25 to No. V3. They were given blood test at 20 days and 40 days after drinking fermented milk, and surveyed about their ordinary life style and the change of fecal condition. Cholesterol, LDL and the ratio of LDL and HDL in blood were significantly decreased in both high cholesterol group and normal group while HDL cholesterol was notably increased. TG showed slightly tendency of decrease in normal group while no changed in high group. There is no significant change in cholesterol level after drinking fermented milk among groups which are divided by factors of dringking, smoking, caffeine, B.M.I. and family history. The research also showed that drinking fermented milk improved the fecal frequency and fecal condition.

• Journal of Nutrition and Health
• /
• 제29권6호
• /
• pp.642-650
• /
• 1996

ApoE 유전자의 다형성은 인체 혈중 콜레스테롤 농도의 정상분포를 설명하는 중요한 인자이다. 특히, E2 와 E4 allele들은 고지혈증환자의 혈중에 현저히 나타나며, 각 다른 인종간의 이틀의 상대빈도수가 관상 동맥 질환 유발 위험도와의 상관관계가 아주 높다. Apo E 유전자의 다형성이 혈중 지질 대사변화 에 미치는 영향에 관한 실험은 105명의 건강한 한국여성을 대상으로 시행되었다. Apo E alleles의 한국 인 상대빈도수는 E3가 0.848, E4가 0.087, 그리고 E2는 0.067이었다. 본 연구에서는 E2/2 표현형이 나 타나지 않았지만, 중국 및 일본인과 같이 E4와 E2 allele가 아주 낮았다 최고및 최저혈압, 맥박(p